83973.m00063

Species: T.vaginalis
Alias: 83973.m00063, TvagK0031
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
83973.m00063.AA Protein None 393 None Fasta, JSON
83973.m00063.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 83973.m00063.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83973.m00063.AA CAMK 21-268 25 9.20000000001e-118 381.22 In-house 1-425 (425) Show / Hide
Range on Protein: 21-268
Range on HMM: 1-425/425
Sequence Identity: 25% (109 aa)

SVGEGAFSIVKLVLNQKTK------------QYYACKVVPRDRLL-------------------------ASSLEERFEVEIRIDQQ-------LHHPGI
  |.|.|..|||. . .|.            | .|.|......|                            . ..... ||.| ..       |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQIVDLLKD-------------------KNNYYVVM---EFCPNG----DLFQFIVDN---------------GRLTEDVGAFYMQQILEALKYVHSLGI
... .   |                   ....| ||   |.|..|    |||..||..               ||.||.  ..|..||..|..| ||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENLLLDAN-----------------NNLKISDFGLSRYVDT------------------------NGLVNTPCGSPCYAS-PECLSG------
.||||||||.||| |                 ||.||.|||.....|                         . . .|.||.|.|.. || |.|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------SAYEGCSSDVWSCGVILYAALTGQLPWTKR-------------NQQQLFEQIKRGEYT-IPNM-----------------------LSDECRD
         | | ..|.||||||||. |.| .|.                |...|||.|..|.|. .| .                       .|.||.|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

FISRLMTVSTSKRMTIDEALKHPWM
.|.....|  .|||||...|.||||
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 83973.m00063.AA AMPK 16-268 42 2e-109 325.98 In-house 1-254 (254) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-254/254
Sequence Identity: 42% (109 aa)

YIFKGSVGEGAFSIVKLVLNQKTKQYYACKVVPRDRLLASSLEERFEVEIRIDQQLHHPGIVQIVDLL-KDKNNYYVVMEFCPNGDLFQFIVDNGRLTED
|| .   |||.|  ||.   . |... | |.  ....  ..  || . ||.| . . || |.|  . . . .   ..|||. ..|.|| .|| .|||.|.
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

VGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNNLKISDFGLSRYVDTNGLVNTPCGSPCYASPECLSGSAYEGCSSDVWSCGVILYAALTGQLPW
  . ..|||. .. |.| ..|.||||||||||||.|.|.|| ||||| .   . .  | |||||||.||  ||  |.|   |.||||||||| | | || 
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPF

TKRNQQQLFEQIKRGEYTIPNMLSDECRDFISRLMTVSTSKRMTIDEALKHPWM
   |. .|.  || |||.||  ||.|..| |... .|   ||.||..  .||| 
DDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase 83973.m00063.AA CAMKL 16-268 33 1.9e-106 340.77 In-house 1-297 (297) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-297/297
Sequence Identity: 33% (101 aa)

YIFKGSVGEGAFSIVKLVLN-QKTKQYYACKVVPRDRLLASSLEERFEV------------EIRIDQQLH---HPGIVQIVDLLKDKNN------YYVVM
|..    |.|.|. ||| .. . |.. .| |.. ....      ..               ||.| ..|.   || |... . . ....      .| ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EFCPNGD--LFQFIVDN----GRLTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANN--NLKISDFGLSRYVDT-----NGLVNTPCGSPCYA
| |..|.  ||..|| .    ||..|.   .| .||..|..| ||.||.|||.||||.||| |.  |.||.|||.| . .      . . .| ||||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPECLSG--SAYEGCSSDVWSCGVILYAALTGQLPWTKR--------NQQQLFEQIKRGEYTIP--NMLSDECRDFISRLMTVSTSKRMTIDEALKHPWM
.|| ..|    |.|   |.||||||||| ..|.||.           |.  |...|..| | .|  . .| .|||.|.....|  .||.||.. ..||||
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





S_TKc 83973.m00063.AA S_TKc 16-268 38 5.8e-103 349.28 SMART 1-231 (231) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-231/231
Sequence Identity: 38% (102 aa)

YIFKGSVGEGAFSIVKLVLNQKTKQYYACKVVPRDRLLASSLEERFEVEIRIDQQLHHPGIVQIVDLLKDKNNYYVVMEFCPN--GDLFQFIVDNGR---
| .   .|.|||. |... . ||....|.|...          |... ||.| .. ||| ||.. |   | ...|.|||.|..  ||||..|...||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNNLKISDFGLSRYVDTNGLVNTPCGSPCYASPECLSGSAYEGCSSDVWSCGVILYAA
   ..| . .|||.||..||.| ||.|| ||||||||.|||   ..||.||||.| .      .| ||.| | .|| |    | .|..|.||||.|||  
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGQLPWTKRNQQQLFEQIKRGEYTIPNMLSDECRDFISRLMTVSTSKRMTIDEALK-------HPWM
|.|. |.   ..|..|..|.          |.|..|||......  .||.|. |||.       |||.
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 83973.m00063.AA MARK 16-268 36 1.8e-93 305.89 In-house 1-262 (262) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-262/262
Sequence Identity: 36% (95 aa)

YIFKGSVGEGAFSIVKLVLNQKTKQYYACKVVPRDRLLASSLEERFEVEIRIDQQLHHPGIVQIVDLLK--DKNN-YYVVMEFCPNGDLFQFIVDN--GR
| ..   |.|... |||.....|.. .| |.... .|      . .. ||.| ..|.|| |..  .     ....  |..|| ...|.|...|.    ||
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANN--NLKISDFGLSRYVDTNGLVNTPCGSPCYASPECLSGSAYEGCSSDVWSCGVILYAAL
|.|.    . .||..|..| || .|.|||.||||.|.|.|.  | ||.|||.|. . .. . || ||.| |..|| ...  |.|   |.||.||.||. .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGQLPWTKRN--QQQLFEQIKRGEYTIPNMLSDECRDFISRLMTVSTSKRMTIDEALKHPWM
.|..|.   .  . .|...| ||.|.|| ..|.|||..|.||.||  ..|.||.| .|||||
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 83973.m00063.AA Pkinase 16-268 33 5e-88 303.55 Pfam 1-293 (293) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-293/293
Sequence Identity: 33% (98 aa)

YIFKGSVGEGAFSIVKLVLNQKTKQYYACKVVPRDRLLASSLEERFEV--EIRIDQQLHHPGIVQIVDLLKDKNNYYVVMEFCPNG----DLFQFIV--D
| ... .|.|.|. |..  ...| . .|.|.....    |. ...     ||.| . |.|| ||.. |   ||...|.|||.|..|    ||| .|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

NGRL--TEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNNL----KISDFGLSRY--VDTNGLVNTPCGSPCYASPECLSGSAYEGCSSDVWS
.|..  .|..  ||| |||..|.| || || ||||||||.|.| |...    ||.||||..      |.  .|.||.| |..|| . |. | | ..|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

CGVILYAALTGQLPWTKR------NQQQLFEQIKRGEYTIPNMLS---------------------DECRDFISRLMTVSTSKRMTIDEALKHPWM
||.|||  |.|..|.  .      .|.|....|.....  .   .                     .||.|||... ..  .|| |....|.|||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 83973.m00063.AA RAD53 16-268 33 3.7e-87 259.59 In-house 1-305 (305) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-305/305
Sequence Identity: 33% (103 aa)

YIFKGSVGEGAFSIVKLVLNQKTKQYYACKVVPRDR-----LLASSLEERFEVEIRIDQQLHHPGIVQIVDLLKDK-NNYYVVMEFCPNGDLFQFIVDNG
|.. . .| |.|..|||... || | .| | .   .       ... ..... |..| . |.|| |..| |   ..  .|| |.|.  .|.|| .||.|.
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

R----LTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANN------------------NLKISDFGLSRYVDTNGLVNTPCGSPCYASPECLSG
|    ..|| . .|  |...|.|| |..||.|||||||| |.....                   .||.|||||. |.   . .| ||.| |  || . .
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

S---------------AYEGCSSDVWSCGVILYAALTGQLPWT-KRNQ----QQLFEQIKR-GEYTI----PNMLSDECRDFISRLMTVSTSKRMTIDEA
.               .| . . |.|| |.|||  |.| .|    . |     |||||||. | |          |.| .|.|... .|   || |||||
KGHNCYHENEERQVQVGY-TKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEA

LKHPWM
| ||||
LNHPWM

Kinase 83973.m00063.AA QIK 16-268 33 6.1e-81 275.21 In-house 1-272 (272) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-272/272
Sequence Identity: 33% (91 aa)

YIFKGSVGEGAFSIVKLVLNQKTKQYYACKVVPRDRLLASSLEERFEVEIRIDQQLHHPGIVQIVDLLKDKNNYYVVMEFCPNGDLFQFIVDNGR-----
|     .| | | .|||  .  ||.  | |.. . .| .. |. . . |. |  .| || |.   . .  ..  |.|.|.|.||..|  .. .||     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNNLKISDFGLSRYVDTNGLVNTPCGSPCYASPECLSGSAYEGCSS
               ..|.. ..  .||. | .| |...|.||||| ||.|||.| | || |||.| .  .  | .| |||| || || . |  |.|  .
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPKV

DVWSCGVILYAALTGQLPWTKRNQQQLFEQIKRGEYTIPNMLSDECRDFISRLMTVSTSKRMTIDEALKHPWM
|.|| ||.||.  .| ||    . |.| . .  | . ||  .| .| ..| . ..|  ..|.||.  ..|.||
DIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase 83973.m00063.AA ULK 16-268 28 1.4e-80 273.99 In-house 1-324 (324) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-324/324
Sequence Identity: 28% (92 aa)

YIFKGSVGEGAFS-IVKLVLNQKT---KQYYACKVVPRDRLLASSLE-------ERFEVEIRIDQQLH---HPG--IVQIVDLLKDK--NNYYVVMEFCP
|. .   |.|.|   |    |.||   .||.|||..... .  ...|       . .. ||.| ..|.   ||   ||.  | ....  ||.| .||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGDLFQFIVDN---------GRLTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNN------------LKISDFGLSRYVDTNG----LVNT
 |||.|.|  |         .||.|.    ...||....|. |. .| |||.||.|.|.  ..             |||.|||... || |.    .  |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

PC------GSPCYASPECLS----GSAYEGCSSDVWSCGVILYAALTGQLP---WTKRNQQ----QLFEQ-------IKRGEYTIP-----NMLSDECRD
 .      |.| | .|. |.    .  |    .|.|| |.|.|  |.|. |   | ...|.    .| ..       ||     .|     . .|.||.|
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

FISRLMTVSTSKRMTIDEALKHPWM
.|.|....  ..|....| ..|||.
LIRRMLQYDEKDRISWEEIFNHPWF

Kinase 83973.m00063.AA ULK 16-268 27 7.5e-80 271.6 In-house 1-329 (329) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-329/329
Sequence Identity: 27% (91 aa)

YIFKGSVGEGAFSIVKLVLNQKTK----QYYACKVVPRDRLLASSLEER-------FEVEIRIDQQLH--------HPGIVQIVDLLKDK--NNYYVVME
|. .   |.|.|  |    |.|||    ...|||..... .  .. |         .. ||.| ..|.        || ||.  | ....  ||.| .||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCPNGDLFQFIVDNGRLTEDV----------GAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNN------------LKISDFGLSRYVDTN----G
.|. |||.|.|  |..|.||.             ...|||...|. |. .| |||.||.| |.. ..             |||.|||... || .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

LVNTPC------GSPCYASPECLS----GSAYEGCSSDVWSCGVILYAALTGQLP---WTKRNQQ-----QLFEQ-------IKRGEYTIP-----NMLS
.  |        |.| | .|. |.    .  |    .|.|| |.|.|  |.|. |   | .. |.     .|...       ||     .|     . .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

DECRDFISRLMTVSTSKRMTIDEALKHPWM
.||.|.|.|....  ..|....| ..|||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF

Kinase 83973.m00063.AA Ciliate-E2 16-268 26 2.5e-79 269.83 In-house 1-365 (365) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-365/365
Sequence Identity: 26% (99 aa)

YIFKGSVGEGAFSIVKLV---LNQK--------------------TKQYYACKVVPRDRLLASSLEERFEVEIRIDQ-----------QLHHPGIVQIVD
|.|    |.|.|..|...   ..||                    ....|| |..  . . . . |..   ||.. .           || || |.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

LLK--DKNNYYVVMEFCPNGDLFQFIVDN-----------GRLTEDVGAFYMQQILE---------------ALKYVHSLG-IAHRDLKPENLLLDANNN
  .  |.||.| |||.|  ||||..| .|           ...||   ...|.|||.               ||.| || . | |||.||||.|.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

LKISDFGLSRYVDTN--------------------------------GLVNTPCGSPCYASPECLSGSAYEG--------CSSDVWSCGVILYAALTGQL
.||.|||||...|..                                 ..|| ||.| | .|| |.|  |..         ..|.||.|||||  |.|..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWTKRNQQQLFEQIKRGEYTIPNM------------------LSDECRDFISR----LMTVSTSKRMT-IDEALKHPWM
|.        ..||| ... .|.                   .|.|| |.|..    .. .  .||.| ....|.|||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 83973.m00063.AA CAMK-Unique 16-268 24 3e-78 257.89 In-house 1-363 (363) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-363/363
Sequence Identity: 24% (89 aa)

YIFKGSVGEGAFSIVKLVLNQKTKQYYACKVVPR-----DRLLA------------SSLEERFEVEIRIDQQLHHPGIVQIVDL----LKDKN-------
|..  ..|.|.|..|. .....|.  .|||.|       .....            . ..  .. |..|.. . || |....|       |..       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NYYVVMEFCPNGDLFQFIVD--------------------NGRLTE--DVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDAN-------
        ..| |||.|. ||||. |..                    .|...|     .|.||..|.|..| ||..| |||||.||...  .       
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---------NNLKISDFGLSRYVDTNGLVN---TPCGSPCYASP--------------ECLSGSAYEGCSS---DVWSCGVILYAALTGQLPWTKRNQQ-
         ...|..||||......|       | ||.|||..|              | . .. | . .|   | ||.|||.|  |.| .| .  .   
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------QLFEQIKRGEY--------TIPNMLSDECRDFISRLMTVSTSKRMTIDEALKHPWM
        .|| |. |.|         .|   |.|  ||. ..|||  ..| .. |.|.|.| 
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase 83973.m00063.AA TyrKc 16-268 25 8.7e-16 32.51 SMART 1-280 (280) Show / Hide
Range on Protein: 16-268
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

YIFKGSVGEGAFSIVKL-VLNQKTKQYYACKVVPRDRLLASSLEERFEVEIRIDQQL--HHPGIVQIVDLLKDK-------NNYYVVMEFCPNGDLFQFI
  ..   ||||| .| . ...    .  | |..  |       .| |  |.||  .|  ||| ||...    ..         ...|||..|.||| ...
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

VDNGR-LTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNNLKISDFGLSRYVDTN------GLVNTP----CG---SPC-YASPECLSGSAY
 .... |. .    .. || .   | || .. ||||   | |...|.  |||||||||...        . . ..    .|    |    .|||.  . .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

EGCSSDVWSCGVILYAALT-GQLPWTK-----RNQQQLFEQIKRGEYTIPNML---------SDECRDFISRLMTVSTSKRMTIDEALKHPWM
    ||||| || ..  .| || |.        . |...|..|.|..  .            .||  . ...      ..| |  |   |  .
-TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 83973.m00063.AA Pkinase_Tyr 87-164 36 1.5e-08 29.56 Pfam 80-161 (270) Show / Hide
Range on Protein: 87-164
Range on HMM: 80-161/270
Sequence Identity: 36% (30 aa)

NNYYVVMEFCPNGDLFQFIVD----NGRLTEDVGAFYMQQILEALKYVHSLGIAHRDLKPENLLLDANNNLKISDFGLSRYV
|..|.|||..|.|||  .  .    ...||      . .|| ... | .| .. ||||   | |.. ||  ||.||||.|..
NQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI

Kinase 83973.m00063.AA Pkinase_Tyr 195-230 33 0.653283 3.71 Pfam 195-233 (270) Show / Hide
Range on Protein: 195-230
Range on HMM: 195-233/270
Sequence Identity: 33% (13 aa)

SDVWSCGVILYAALT-GQLP-WTKRNQQQLFEQI-KRGE
||||| || ..  .| |. | .     ....|.| ..|.
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY