Gene 86673.m00362 (T.vaginalis)

86673.m00362

Species: T.vaginalis
Alias: 86673.m00362, TvagK0681
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
86673.m00362.AA Protein None 386 None Fasta, JSON
86673.m00362.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 86673.m00362.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86673.m00362.AA Ciliate-E2 6-259 19 1.3e-44 151.03 In-house 1-365 (365) Show / Hide 
Range on Protein: 6-259
Range on HMM: 1-365/365
Sequence Identity: 19% (72 aa)

YIIEETLNKKPGSSVYLVNNKDDKD-----------------EKFIVKKYNKDLLTKEETERLQKEMKILV----------------KLKCSNIIRYYQY
|.. . . .   .|||..... ..                  ||. .|.|..  . | . | . .| .|.                 .|.. |||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

KQ--SPGHVSVLMEYANNGTLEDFLENRRENN-------VRMKTDNIIDIFTQLC---------------IGMKYLHDRK-IVHRNLIPSVIFLTSQNIV
 |  .  ..   |||.. |.|.|...|.. .         ...   |..|..|..                ...||| .. |.||.. |. |..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIGGLESFK-----PLENTDSLISSLILPEED------------------------NLDYIAPEIQRGEK---------YTAKSDIWSLGCLLYEMCSLK
||  .   |       ..|. .  . ....                          .. | |||| .|.|         |. |.||||||..||||.. |
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

K---VNLLNCDLTRAPK--------------IGSSFPKELSDLVEA----MVNSNPEKRPS-INEILNKDII
     . ..|..   ..              .  . ..|  ||       | . .||||.. ...|||  ..
PPFQQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86673.m00362.AA Ciliate-E2-Unclassified 6-206 19 4.4e-35 119.14 In-house 1-264 (352) Show / Hide 
Range on Protein: 6-206
Range on HMM: 1-264/352
Sequence Identity: 19% (52 aa)

YIIEETLNKKPGSSVYLVNNKDDKDEK------FIVKKYN-KDLLTK-------EETERLQ--------KEMK-ILVKLKCSNIIRYYQYKQSPGHVSVL
|.| .....   ..||.. .|..| ..        ...|. |  ..|       .| ....        |.|. ||. ... .|.... ..|.  ..   
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYANNGTLEDFLE-------------NRRENNVRMKTDNII-----DIFTQLCIGMKYLHDRK-IVHRNLIPSVIFLTSQN---IVKIGGLESFKPLE-
|||...|.|.....             ...... .    ...     ..| |.. | .|||  . |.||.. |. |......    .|| .. ..| .. 
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----------NTDSLISSLILPEEDNLDYI----APEIQRGEKYT----AKSDIWSLGCLLYEMC
          ... ... ..     .. |.    |||. .|..|      |.||||||..||||.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEML
Kinase 86673.m00362.AA S_TKc 6-259 24 4.6e-33 117.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-259
Range on HMM: 1-231/231
Sequence Identity: 24% (66 aa)

YIIEETLNKKPGSSVYLVNNKDDKDEKFIVKKYNKDLLTKEETERLQKEMKILVKLKCSNIIRYYQYKQSPGHVSVLMEYANN--GTLEDFLENRRENNV
| | ... |   ..||.. .|.  .... .|. .         |....|..|| | .. ||...| . |. .|. . |||...  |.| |....|. .  
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

R--MKTDNIIDIFTQLCIGMKYLHDRKIVHRNLIPSVIFLTSQNIVKIGGLESFKPLENTDSLISSLILPEEDNLDYIAPEIQRGEKYTA-KSDIWSLGC
|  .    .  .. |.| ...|.|...|.|| | |. |.|..   .||.   . . |   .... .        ..|.|||.    .|.  |.|.||.||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGT--------PWYMAPEVL---GYGKCKCDWWSCGC

LLYEMCSLKKVNLLNCDLTRAPKIGSSFPKELSDLVEAMVNSNPEKRPSINEILN-------KDII
.||||.. .       . .   |||   ..|. |... . . .|||||.. |.|.          .
ILYEMLCGYPPFP--QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86673.m00362.AA STE 6-259 17 1.8e-30 104.84 In-house 1-359 (359) Show / Hide 
Range on Protein: 6-259
Range on HMM: 1-359/359
Sequence Identity: 17% (67 aa)

YIIEETLNKKPGSSVYLVNNKD-----DKDEK---------FIVKKYNKD-------------LLTK--EETERLQKEMKILVKLK--CSNIIRYYQYKQ
. . | . |  . .||.  |..     ...|.         . .|. |..             | .|  || ....||.||. |..  . ||..|| .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SPG-------HVSVLMEYANNGTLEDFLENR----RENN------VRMKTDNIIDIFTQLCIG-MKYLHDRKIVHRNLIPSVIFLTSQNIVKIGGLESFK
  |       .. . ||| ..|.|.|.....    ...|       |.. . |. |  |.. | ..|||. .|.|| . |. |.|     ||.      .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

PLEN--------------------TDSLISSLILPEEDNLDYIAPEIQRG------EKYTAKSDIWSLGCLL-------YEMCSLK--KVNLLNCDL---
 |..                    ..... .          . |||. ..       .|..|.|||||||..       .... ..  .. ..  .    
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP---------WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

-----------TRAPKIGS-------------------SFPKELSDLVEAMVNSNPEKRPSINEILN--KDII
              |.. .                   .. .|. | ..   . .|.|||. .. |.     |
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 86673.m00362.AA TKL 35-257 16 1.5e-27 96.32 In-house 31-364 (364) Show / Hide 
Range on Protein: 35-257
Range on HMM: 31-364/364
Sequence Identity: 16% (57 aa)

VKKYNKDLLTKEET-------------------------ERLQKEMKILVKLKCSNIIRYYQYKQSPGH-------------VSVLMEYANNGTLEDFLE
|||....   ...                          ... .|.... .|.. ||.... | ..|..                 |||. .|.|...| 
VKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH

NRRENNVRMKTDNIIDIFTQLCIGMKYLHDRK--------IVHRNLIPSVIFLTSQNI--------------VKIG--GLESFKPLENTDSLISSL----
           . ....  . . || ||| ..        |.||.| .. |.. . .               .||.  ||  |.  .. .. ...     
----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMES

--------ILPEED-NLDYIAPEIQRGE----------------KYTAKSDIWSLGCLLYEMCSLKKVN------------------LLNCDLTRAPKIG
         .  .  .. . |||. ||.                .|. |.|..| | .|.|... ...                    ..||  . | | 
AEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIP

------------SSFPKELSDLVEAMVNSNPEKRPSINEILNKD
            ...|.....| .   ...|||||| .||| . 
PIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 86673.m00362.AA NEK4 20-209 30 2e-26 91.97 In-house 15-199 (257) Show / Hide 
Range on Protein: 20-209
Range on HMM: 15-199/257
Sequence Identity: 30% (59 aa)

VYLVNNKDDKDEKFIVKKYNKDLL--TKEETERLQKEMKILVKLKCSNIIRYYQ-YKQSPG-HVSVLMEYANNGTLEDFLENRRENNVRMKTDNIIDIFT
|.|| .. ||  ....|| .  |.   ..|.    .| ..| .||  ||. |   ..   |    . | . . | |  .   ..  |  ..   ... | 
VWLVRHRRDK-KQYVMKKMF--LKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDL--YRKLKQQKNQFLEEYQVVEWFV

QLCIGMKYLHDRKIVHRNLIPSVIFLTSQNIVKIGGLESFKPLENTDSLISSLILPEEDNLDYIAPEIQRGEKYTAKSDIWSLGCLLYEMCSLK
|  ... |.|...|.|| |    |||| .||.||| .   . |.|   . . .|        |. ||.     |  ||||||||| .|||  ||
QIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMI----GTPYYMSPECFGNRPYDYKSDIWSLGCCVYEMITLK
Kinase 86673.m00362.AA NEK 18-150 31 2.3e-25 86.55 In-house 13-165 (286) Show / Hide 
Range on Protein: 18-150
Range on HMM: 13-165/286
Sequence Identity: 31% (48 aa)

SSVYLVNNKDDKDE----KFIVKKYNKDLLTKEETERLQ-KEMKILVKLKCSNIIRYYQYKQSPG--HVSVLMEYAN-NGTLEDF---LENRRENNVRMK
..||.|  | |...    ... || | . .. .|.. .| .| .|| .||. ||..||   .  .  .    |||.. .|.|...   ...... .  . 
GKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFE

TDNIIDIFTQLCIGMKYLHDR-----KIVHRNLIPSVIFLTSQNI----VKIG
 . | |.|.|.|...||.|||     ||.|| . |. ||||..|.    ||||
EEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIG
Kinase 86673.m00362.AA ULK 25-150 24 2.9e-21 72.23 In-house 21-180 (324) Show / Hide 
Range on Protein: 25-150
Range on HMM: 21-180/324
Sequence Identity: 24% (39 aa)

NKDDK--DEKFIVKKYNKDLLTKEETE--------RLQKEMKILVKLK---CSN--IIRYYQYKQSPGH--VSVLMEYANNGTLEDFLENRRE-----NN
||...  .... .|. .|. . | . |         |..| .|. |||   . |  |...| ..... |  .   ||| | |.||........     ..
NKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEK

VRMKTDNIIDIFTQLCIGMKYLHDRKIVHRNLIPSVIFLTS------------QNIVKIG
 |   . .| .| |.| |.|.||...|.|| . |. | ..             ....||.
KRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIA
Kinase 86673.m00362.AA ULK 25-150 24 8.3e-21 69.42 In-house 20-184 (329) Show / Hide 
Range on Protein: 25-150
Range on HMM: 20-184/329
Sequence Identity: 24% (41 aa)

NKDDK---DEKFIVKKYNKDLLTKEETER--------LQKEMKILVKLK--------CSNIIRYYQYKQSPGH--VSVLMEYANNGTLEDFLENRRE---
||..|   .||...|.  |. . ... |.        |..| ||. |||        . ||...| ..... |  .   ||| | |.||........   
NKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPE

---NNVRMKTDNIIDIFTQLCIGMKYLHDRKIVHRNLIPSVIFLTS------------QNIVKIG
   .. |   . .| .| |.. |.|.||...|.|| . |. | ..             ....||.
DTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIA
Kinase 86673.m00362.AA Pkinase 18-132 21 4e-20 72.25 Pfam 13-132 (293) Show / Hide 
Range on Protein: 18-132
Range on HMM: 13-132/293
Sequence Identity: 21% (27 aa)

SSVYLVNNKDDKDEKFIVKKYNKDLLTKEETERLQK--EMKILVKLKCSNIIRYYQYKQSPGHVSVLMEYANNG----TLEDFLENRRENNVRM--KTDN
..||.  .|.. . .. ||. .|.   ... ... .  | .|. .|.. ||.|.| . ....|. . |||...|     | |...   ... ..    . 
GCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--WRHGCFYFSEWE

IIDIFTQLCIGMKYLHDRKIVHR
......|.. |..|.|...|.||
CKFYMYQILRGLEYCHSMGIIHR
Kinase 86673.m00362.AA NEK1 45-150 28 9.8e-20 65.25 In-house 39-163 (276) Show / Hide 
Range on Protein: 45-150
Range on HMM: 39-163/276
Sequence Identity: 28% (35 aa)

KEETERLQKEMKILVKLKCSNIIRYYQYKQSPGH--VSVLMEYANNGTLEDFLENRRENNVRMKTDNIIDIFTQLCIGMKYLHDRKIVHRNLIPSVIFLT
..|.|.  .| .|| |.|  ||..|.   .  |.      |||...| |    ....  ..    | | . |.|.|..... ||||| || . .. ||||
EKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKLFSEDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLT

--SQN---------------IVKIG
  .                 .||.|
ISKNGMGSGSGSGSSNDSIPLVKLG
Kinase 86673.m00362.AA NEK8 178-211 55 8e-19 50.25 In-house 188-221 (278) Show / Hide 
Range on Protein: 178-211
Range on HMM: 188-221/278
Sequence Identity: 55% (19 aa)

YIAPEIQRGEKYTAKSDIWSLGCLLYEMCSLKKV
|. ||.  | .| .|||.|.||| |||||.||..
YMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRA
Kinase 86673.m00362.AA NEK8 83-150 27 2.3e-16 43.1 In-house 79-162 (278) Show / Hide 
Range on Protein: 83-150
Range on HMM: 79-162/278
Sequence Identity: 27% (23 aa)

MEYANNGTLEDFLENRRE-NNVRMK--------------TDNIIDIFTQLCIGMKYLHDRKIVHRNLIPSVIFLTSQ-NIVKIG
||||. |||....  ..      ..                 |.. |.| |..  ..|.  |.|| | .  ||.|   ..||||
MEYADGGTLYQMIQHQQNKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMTRHRMVVKIG
Kinase 86673.m00362.AA NEK 178-210 57 2.6e-16 54.26 In-house 190-224 (286) Show / Hide 
Range on Protein: 178-210
Range on HMM: 190-224/286
Sequence Identity: 57% (20 aa)

YIAPEIQRGEKYTAKSDIWSLGCLLYEMCSL--KK
|..||. ....|. |||||||||.|||||.|  |.
YMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKH
Kinase 86673.m00362.AA Pkinase 176-259 22 1.2e-14 52.93 Pfam 175-293 (293) Show / Hide 
Range on Protein: 176-259
Range on HMM: 175-293/293
Sequence Identity: 22% (27 aa)

LDYIAPEIQR-GEKYTAKSDIWSLGCLLYEMCSLKKVNLLNC------------DLTRAPKIGSSFP-----------------------KELSDLVEAM
..|.|||. | |..|. |.|.||.||.||||.. ..    ..            .... |.. ...|                       .|. |... .
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

VNSNPEKRPSINEILNKDII
 . .|.|||.. .||. . .
LCKDPKKRPTAEQILQHPWF
Kinase 86673.m00362.AA ULK 178-259 25 1.4e-14 47.37 In-house 217-329 (329) Show / Hide 
Range on Protein: 178-259
Range on HMM: 217-329/329
Sequence Identity: 25% (29 aa)

YIAPEIQR----GEKYT-AKSDIWSLGCLLYEMCSLKKV-----NLLN-----CDLTRAPKIG-------SSFP---------KELSDLVEAMVNSNPEK
| ||.|      ...|. .|.|||||||..|||   |       | ..       .   |...         ||         .|. ||   |   ....
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKD

RPSINEILNKDII
| |. |..|  ..
RISWEELFNHPWF
Kinase 86673.m00362.AA Pkinase_Tyr 35-134 29 1.3e-13 46.75 Pfam 33-137 (270) Show / Hide 
Range on Protein: 35-134
Range on HMM: 33-137/270
Sequence Identity: 29% (31 aa)

VKKYNKDLLTKEE--TERLQKEMKILVKL-KCSNIIRYY--QY-KQSPGHVSVLMEYANNGTLEDFLENRRENNVRMKTDNIIDIFTQLCIGMKYLHDRK
||.  |.  ..|.   | . .|.||. .| .. ||.|.|   . .. |... . |||. .| | |.| ..||.. . ..  .... .| . || ||....
VKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN

IVHRNL
..|| |
CIHRDL
Kinase 86673.m00362.AA TyrKc 10-259 21 2.6e-13 -7.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-259
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

ETLNKKPGS----SVYLVNNKDDKDEKFIVKKYNKDLLTKEETERLQKEMKILVKL--KCSNIIRYYQYKQSP-------GHVSVLMEYANNGTLEDFLE
 ||.|| |.     ||.   |    ..  ||. ..|       | . .|..|. ||  .  ||.| | .  ..       . . ..|||. .| | |.| 
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NRRENNVRMKTDNIIDIFTQLCIGMKYLHDRKIVHRNLIPSVIFLTSQNIVKIG--GLESFKPLE-----NTDSLIS----SLI--LPEEDNLDYIAPEI
..|..    ...  ... .| . || |||.....|| |    . ......|||.  ||  .   .     ..|   .    .    ||    .   ||| 
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP----IRWMAPEC

QRGEKYTAKSDIWSLGCLLYEMCS-------------LKKVNLLNCDLTR-APKIGSS--------FPKELSDLVEAMVNSNPEKRPSINEILNKDII
 .  |.| |||.|| | ...|...             ..   ....  ..  ...  .         |.|. .. .   . .||.||. .||  ....
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 86673.m00362.AA ULK 178-259 23 2.7e-13 43.6 In-house 213-324 (324) Show / Hide 
Range on Protein: 178-259
Range on HMM: 213-324/324
Sequence Identity: 23% (27 aa)

YIAPEIQR----GEKYT-AKSDIWSLGCLLYEMCSLKKV---NLLNCDL------------------TRAPKIG---SSFP--KELSDLVEAMVNSNPEK
| ||.|.     ...|. .|.|||||||..|||   |     .  | .                   ..  ..    .. .  .|. ||   |   ....
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKD

RPSINEILNKDII
| |. ||.|  ..
RISWEEIFNHPWF
Kinase 86673.m00362.AA NEK 222-259 37 2.8e-11 36.39 In-house 247-286 (286) Show / Hide 
Range on Protein: 222-259
Range on HMM: 247-286/286
Sequence Identity: 37% (15 aa)

PKIGSS--FPKELSDLVEAMVNSNPEKRPSINEILNKDII
|.| |   . ..|..|.. | . .||.|||.|.||.. .|
PPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 86673.m00362.AA NEK1 178-209 62 4.6e-11 34.78 In-house 187-218 (276) Show / Hide 
Range on Protein: 178-209
Range on HMM: 187-218/276
Sequence Identity: 62% (20 aa)

YIAPEIQRGEKYTAKSDIWSLGCLLYEMCSLK
|. |||     |. ||||||||| ||| | ||
YLSPEICQNKPYNNKSDIWSLGCVLYELCTLK
Kinase 86673.m00362.AA NEK1 222-259 42 8.9e-10 30.26 In-house 239-276 (276) Show / Hide 
Range on Protein: 222-259
Range on HMM: 239-276/276
Sequence Identity: 42% (16 aa)

PKIGSSFPKELSDLVEAMVNSNPEKRPSINEILNKDII
|.| . . .||. ||  | . ||. |||.| || . .|
PPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase 86673.m00362.AA NEK4 224-259 33 6e-06 17.56 In-house 222-257 (257) Show / Hide 
Range on Protein: 224-259
Range on HMM: 222-257/257
Sequence Identity: 33% (12 aa)

IGSSFPKELSDLVEAMVNSNPEKRPSINEILNKDII
.   . ..| .||  | .  |.||||| .|. .  |
MPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 86673.m00362.AA Ciliate-E2-Unclassified 229-259 28 2.2e-05 14.67 In-house 318-352 (352) Show / Hide 
Range on Protein: 229-259
Range on HMM: 318-352/352
Sequence Identity: 28% (10 aa)

PKELSDLVE----AMVNSNPEKRPSINEILNKDII
..|  |...     | . ||.||.....|||  ..
SPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86673.m00362.AA Pkinase_Tyr 180-208 46 3e-05 18.42 Pfam 182-210 (270) Show / Hide 
Range on Protein: 180-208
Range on HMM: 182-210/270
Sequence Identity: 46% (14 aa)

APE-IQRGEKYTAKSDIWSLGCLLYEMCSL
||| |. |. .| |||.|| | |..|....
APECINYGK-FTTKSDVWSFGVLMWEIFTY
Kinase 86673.m00362.AA NEK8 224-259 27 0.002172 5.4 In-house 243-278 (278) Show / Hide 
Range on Protein: 224-259
Range on HMM: 243-278/278
Sequence Identity: 27% (10 aa)

IGSSFPKELSDLVEAMVNSNPEKRPSINEILNKDII
|..   .|.  ||..     ||.|||  .|.    .
ISDHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC