Gene 83948.m00059 (T.vaginalis)

83948.m00059

Species: T.vaginalis
Alias: TvagK0167, 83948.m00059
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
83948.m00059.AA Protein None 310 None Fasta, JSON
83948.m00059.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of 83948.m00059.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 83948.m00059.AA S_TKc 12-268 28 1.5e-71 244.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-268
Range on HMM: 1-231/231
Sequence Identity: 28% (75 aa)

YISNGPIGKGGFGSCYLITSTRYNQQFACKVIDSANHSSEENTNSFHREVSALIHLDHPNIIQIYDVFEEQQQKFIILEYCSG--GNLKDLIDKYHG---
|    .||||.||..|. . .. ....|.|.|.          ... ||.. | . .||||...||||.. .  ....|||.|  |.|.|.|.|. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IKGDLLIQYSMQIIDALKFCHFNGYSHNDIKPANVFITSHGQLKLADFGLTEHNVLDTCKYVGSFDYMAPEVIQKIPHDPMKSDIWSLGVTLYQLAS
   .       |  ||..||..|| .|  | |.||.|.....  ..|..||||  .       ..|. .||||||.   .... |.|.||.|..|| ...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GELPFGATNGSELLYEIKMGYEKIHGIDQAFSALIKMCLSRNPLKRPSITHVQSCVKKIKENDYS
|. ||      ...... .        .. .  .|. || ..| |||..  .     .||   . 
GYPPFP---QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 83948.m00059.AA Pkinase 12-259 25 9.4e-63 219.59 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-259
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

YISNGPIGKGGFGSCYLITSTRYNQQFACKVIDSANHSSEENTNSFH-REVSALIHLDHPNIIQIYDVFEEQQQKFIILEYCSGG----NLKDLID--KY
|   ..||.|.||..|. .   .....|.|.|.  . .|... . .. .|.. . .|.||||...||.||. .   ...||| ||     |.|.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HGI--KGDLLIQYSMQIIDALKFCHFNGYSHNDIKPANVFITSHGQL----KLADFGL-----TEHNVLDTCKYVGSFDYMAPEVIQKIPHDPMKSDIWS
 ..    . .. |  ||. .|..|| .|  | |.||.|..| ..|..    |..||||     . .|.  .  ..|. .|||||||.. .... |.|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGVTLYQLASGELPFGAT------NGSELLYEIKM---GYEKIHGID-------------------QAFSALIKMCLSRNPLKRPSITHVQSC--V
.|..||....|..||         .  .....|..    ..    ..                   ...  .|| || ..| |||.....     .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83948.m00059.AA CAMK 17-253 18 9.3e-59 187.63 In-house 1-417 (425) Show / Hide 
Range on Protein: 17-253
Range on HMM: 1-417/425
Sequence Identity: 18% (77 aa)

PIGKGGFGSCYLITSTRYN------------QQFACKVIDSANHSS-------------------------EENTNSFHREVSALIH-------LDHPNI
 .|.|.||  .| . .. .            |..|.|.||   ...                         ...  .. ||.. . .       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQIYDVFEE-------------------QQQKFIIL---EYCSGG----NLKDLIDKYHG---------------IKGDLLIQYSMQIIDALKFCHFNGY
|..|.|.|                    ... ....   ||||||     | | | .  .               .. .   .|  ||..|...|| .. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHNDIKPANVFITSH-----------------GQLKLADFGLT-----EHNVL---------------------DTCKYVGSFDYMA-PEVIQK------
 | |.|| |. ....                 ...|..|||.       .| .                         ..|.  ||| |||...      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------IPHDPMKSDIWSLGVTLYQLASGELPFGATNGSELLY-------------EIKMGYEK-IHG----------------IDQA--------FSA
       .| .. |.|.||.|| || . .|..|| . ...| .               |. |    ..                 | .            
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIKMCLSRNPLKRPSIT
||. .| ..| ||..|.
LIRKMLQVDPEKRMTIE
Kinase 83948.m00059.AA ULK 12-249 27 2.1e-55 190.39 In-house 1-312 (324) Show / Hide 
Range on Protein: 12-249
Range on HMM: 1-312/324
Sequence Identity: 27% (85 aa)

YISNGPIGKGGFG-SCYLITSTRY---NQQFACKVID--SANHSSEENT-----NSFHREVSALIHLD---HPN--IIQIYDVFEEQ--QQKFIILEYCS
|. |  .||| ||   |  .  .    ||..|||.||  . | .. |..     ... .|.. .  |.   |||  |.. ||.||..     .||.||| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGNLKDLIDKYHG---------IKGDLLIQYSMQIIDALKFCHFNGYSHNDIKPANVFITS------------HGQLKLADFGLTEH--------NVLDT
||.|...| |...         .  .  ||. .||. ..|. | ... | ||||.|  |.             .|.||.||||.  |        ... |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

CK----YVGSFDYMAPEVIQ----KIPHDPMKSDIWSLGVTLYQLASGELPFGATNGSELL------------YEIKMGYEKI--H------GIDQAFSA
|.    ..|.  ||||...|    ..|..  |.||||||. .|..  |. || .   ...             ..|.. ...|          | . .  
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LIKMCLSRNPLKR
||. .| ... .|
LIRRMLQYDEKDR
Kinase 83948.m00059.AA CAMKL 12-252 30 2.3e-55 175.09 In-house 1-288 (297) Show / Hide 
Range on Protein: 12-252
Range on HMM: 1-288/297
Sequence Identity: 30% (89 aa)

YISNGPIGKGGFGSCYLITSTRY-NQQFACKVIDSANHSSEENTNSF------------HREVSALIHLD---HPNIIQIYDVFEEQQQ------KFIIL
|.    .|||.||   | | .|. ... | |.||    . ......              ||.. . .|.   |||||..|.|.| ..        ....
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCSGGN--LKDLIDKYHG----IKGDLLIQYSMQIIDALKFCHFNGYSHNDIKPANVFITSHG--QLKLADFGLT---------EHNVLDTCKYVGSFD
||||||.  | | |.|  .    .. .   .|  ||..|...|| .|  | |||| |. ....|  ..|..|||.          . . |.|.   ||  
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF--CGSPP

YMAPEVIQK--IPHDPMKSDIWSLGVTLYQLASGELPFGATN-------GSELLYEIKMGYEKIHG----IDQAFSALIKMCLSRNPLKRPSI
|||||..|.   |.|  | ||||.||.|| .  |.||| . .          .||...|.  .       ..     ||.  | .|| |||.|
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI
Kinase 83948.m00059.AA ULK 12-221 29 6.5e-54 185.43 In-house 1-269 (329) Show / Hide 
Range on Protein: 12-221
Range on HMM: 1-269/329
Sequence Identity: 29% (79 aa)

YISNGPIGKGGFGSCYLITSTRY----NQQFACKVIDSA--NHSSEEN-----TNSFHREVSALIHLD--------HPNIIQIYDVFEEQ--QQKFIILE
|. |  .||| ||  |  .  .     |...|||.||.   | .. |.      ... .|.  .  |.        ||||.. ||.||..     .||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCSGGNLKDLIDKYHG----------IKGDLLIQYSMQIIDALKFCHFNGYSHNDIKPANVFITSH------------GQLKLADFGLTEH---N-----
|| ||.|...| |...          .  .  ||. .||. ..|. | ... | ||||.|. |. .            |.||.||||.  |   .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

VLDTCK----YVGSFDYMAPEVIQ----KIPHDPMKSDIWSLGVTLYQLASGELPFGATNGSELL-YEIK
.. ||.    . |.  ||||...|    ..|..  |.||||||. .|..  |. || |   ...  . |.
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQ
Kinase 83948.m00059.AA AGC 12-250 18 1.2e-53 136.01 In-house 1-374 (395) Show / Hide 
Range on Protein: 12-250
Range on HMM: 1-374/395
Sequence Identity: 18% (69 aa)

YISNGPIGKGGFGSCYLITST------RYNQQFACKVIDSAN--------HSSEENTNS-------FHREVSALIHLD----------HPNIIQ-IYDVF
.    .||||.|| .||            ....|.||.. .              .| .       . .|   | ...          ||.|..  .  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

EEQQQ--KFIILEYCS---------GG-NLKDLI--D-KYHGIKGDLLIQYSMQ-------IIDALKFCHF-NGYSHND-IKPANVFITSHGQLKLADFG
. ..    ....||..         ||  |   .  . |.     .    |  .       |. || . |  .|. | | .|| |. ....| .||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LTEHNVLD-----------------------------------------------------TCKYVG--SFDYMAPEVIQKIPHDPMKSDIWS--LGVTL
|   .. |                                                     |   .|  . .|||||..    ...   |.||  ||. .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKA-CDWWSFGLGCLM

YQLASGELPFGATN---------GSELLYEIKM-------GYEKI-----------HGIDQAFSALIKMCLSRNPLKRP
|.. .|  || . |           . ...  |         .|.             ...    |||..| ..| ||.
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRL
Kinase 83948.m00059.AA Ciliate-E2 12-252 20 2e-48 164.35 In-house 1-356 (365) Show / Hide 
Range on Protein: 12-252
Range on HMM: 1-356/365
Sequence Identity: 20% (77 aa)

YISNGPIGKGGFGSCYLITSTRYNQQFACKVIDSAN------------------HSSEENTNSFHREVSALI----------------HLDHPNIIQIYD
|. .  ||.|.||| |. .  . ..||| |.||  .                    .. . ... .| . .                 .|.|||||..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

VFE--EQQQKFIILEYCSGGNLKDLID------------KYHGIKGDLLIQYSMQIID---------------ALKFCHFNG-YSHNDIKPANVFITSHG
.|.   ..  ....|||.||.|.|.|             . . ..    .... ||..               ||...| ..   | |||| |...    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

QLKLADFGLTEHNVLD--------TCK--------------------------YVGSFDYMAPEVIQKIP--------HDPMKSDIWSLGVTLYQLASGE
 .|..||||   .  |         ||                          ..|.  |||||.... .        .   |.|||||||.||.. .|.
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

LPFGATNGSELLYEIKMG----YE----------------KIHGIDQAFSALIKM----CLSRNPLKRPS-I
.||         .....     .                 . . ..|    |||     .| ..| ||.. .
PPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGW
Kinase 83948.m00059.AA Ciliate-E2-Unclassified 12-252 21 1.6e-47 162.91 In-house 1-343 (352) Show / Hide 
Range on Protein: 12-252
Range on HMM: 1-343/352
Sequence Identity: 21% (74 aa)

YISNGPIGKGGFGSCYLITSTRYNQQF-----ACKVIDSANHS-------------SEENTNSFHREVS-------ALIHLDHPNIIQIYDVFEEQQQKF
|. .  ||.||||. |.      . |.     ..|... . ..              ... . .| . .        |....||.|.  ...|. .|  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQR-KYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

IILEYCSGGNLKDLIDKYHG-----------------IKGDLLI-----QYSMQIIDALKFCHFNG-YSHNDIKPANVFITSHG---QLKLADFGL----
|..||| ||.|.. | |...                 .     .     .|  ||...|...| ..   | |||| |..... |   ..|..|||.    
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

------TEHN------VLDTCKY---VGSFDYM----APEVIQKIPHDPM---KSDIWSLGVTLYQLASGELPFGATNGSE---------------LLYE
      . .|      ... ...   .|.  ||    ||||.|.  .| .   |.||||||| ||..  |..||...|  .                ||.
QQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

IKMGY------EKI----HGIDQAFSALIK----MCLSRNPLKRPSI
...        ..     .....    .|.     .|  || ||...
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITF
Kinase 83948.m00059.AA STE 13-251 20 1.6e-45 157.58 In-house 1-347 (359) Show / Hide 
Range on Protein: 13-251
Range on HMM: 1-347/359
Sequence Identity: 20% (74 aa)

ISN-GPIGKGGFGSCYLITST------RYNQQ---------FACKVIDSANHSS--------------EENTNSFHREVSALIHLD--HPNIIQIYDVFE
  . . ||||.||. |.          . ...         .| |...  | ..              .|. ... .|.. . ...  ||||.. |. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EQ-------QQKFIILEYCSGGNLKDLIDKYHGIKG--------------DLLIQYSMQIIDA-LKFCHFNGYSHNDIKPANVFITSHGQLKLADFGLTE
         .. .|..||..|| | |.|....|...              .... .  ||. . |.. | ... | ||||||...      ||.|||.  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

HNVLD--------------TCK-----YVGSFDYMAPEVIQK------IPHDPMKSDIWSLGVTLYQLASGELPFGATNGSELLYEIKMGY---------
  . .              |..      ||.  .|||||||.       ..|  |.|||||| |.  .| |. |.   .  . ...| ..|         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----EKIHGID-----------------------QAFSALIKMCLSRNPLKRPS
    ...  .                        . |   |. || ..| |||.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT
Kinase 83948.m00059.AA NEK 12-259 29 2.1e-42 147.17 In-house 1-286 (286) Show / Hide 
Range on Protein: 12-259
Range on HMM: 1-286/286
Sequence Identity: 29% (86 aa)

YISNGPIGKGGFGSCYLITSTRYNQQ-----FACKVIDSANHSSEENTNSFH-REVSALIHLDHPNIIQIYDVFEEQQ--QKFIILEYCS-GGNLKDL--
|     ||.| ||..|.. ... ...     .. | |.  .. ||...      ||  | .|.||||.  || |.|.|  . .|. |||  ||.| ..  
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN-MGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

-IDKYH----GIKGDLLIQYSMQIIDALKFCHFN-----GYSHNDIKPANVFITSHGQ----LKLADFGL---TEHN--VLDTCKYVGSFDYMAPEVIQK
 | |.      .  .    .  |.. |||..| .        | ||||.|.|.|. .     .|. |||.    .|.   . |  .||   ||.|||.| 
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYT-TQVGTPYYMSPEVCQN

IPHDPMKSDIWSLGVTLYQLASG--ELPFGAT--NGSELLYEIKMGYEKIHGIDQA--F----SALIKMCLSRNPLKRPSITH--VQSCV
 | .  ||||||||. ||....   . || |.  |  .| . |. | ..   | .   .    . || ..| ..| .|||..    ....
KPYN-NKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKG-PQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase 83948.m00059.AA TKL 18-259 16 4.6e-39 136.1 In-house 1-364 (364) Show / Hide 
Range on Protein: 18-259
Range on HMM: 1-364/364
Sequence Identity: 16% (60 aa)

IGKGGFGSCYLITSTRYN--------QQFACKVIDSAN----------------------HSSEENTNSFHREVSALIHLD--HPNIIQIYDVFEEQQQ-
||.||||  |  .    .        .  | |.. | |                      .. |   . |..|. .....   ||||.|.. .  . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KFIILEYCSGGN-LKDLIDKYHGIKGDLLIQYSMQIIDALKFCHFNG--------YSHNDIKPANVFITSHGQ--------------L
             .|. |||.||. | .|.        ..... ...|  .. . | ..          | |.|..|... ....              .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KLADFGLTEHNVLD----------------------TCKYVGSFDYMAPEVIQKIPHDP---------------MKSDIWSLGVTLYQLASGELPFGATN
|..||||   .  .                      |.. .|.. .|||||... . ..                |.|..| |. |. ......|.   .
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

GSELL------YEIKMGYEKI------------------HGIDQAFSALIKMCLSRNPLKRPSITHVQSCV
 .. .       ...| ..|                   . ... .. |...| . .| |||| . . .  
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 83948.m00059.AA TyrKc 12-259 22 2.9e-16 40.37 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-259
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YISNGPIGKGGFGSCYLITSTRYNQQFACKVIDSANHSSEENTNSFHREVSALIHL--DHPNIIQIYDVFEEQ-------QQKFIILEYCSGGNLKDLID
   .  .| | ||  |. | .   .| | |.. .           |.|| . . .|  .||||...| |  .|       .. .|..||...|.||| . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KYHG-IKGDLLIQYSMQIIDALKFCHFNGYSHNDIKPANVFITSHGQLKLADFGLTEHNVLD----------------TCKYVGSFDYMAPEVIQKIPHD
|... .. . |.... || .   . | ... | |.   |. ... .. | .||||.     |                 .|..     ||||.|     .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----N

PM----KSDIWSLGVTLYQLAS-GELPFGA-----TNGSELLYEIKMGY--EKIHG--------IDQAFSALIKMCLSRNPLKRPSITHVQSCV
      |||.|| ||... . . |. |         . .|..  .| ||  .. .           ..   ..|.|  ..| .||. . . .| 
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 83948.m00059.AA Pkinase_Tyr 47-157 26 1.7e-11 39.59 Pfam 38-158 (270) Show / Hide 
Range on Protein: 47-157
Range on HMM: 38-158/270
Sequence Identity: 26% (32 aa)

NHSSEEN--TNSFHREVSALIHL-DHPNIIQIYDVFEEQQQK---FIILEYCSGGNLKDLIDKY----HGIKGDLLIQYSMQIIDALKFCHFNGYSHNDI
.....|.    .| ||.. . .| .||||.. | |  .|..    .|..||. .|.|.|   |     . ..   |.|...|| ... . . ... | |.
EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL

KPANVFITSHGQLKLADFGLT
   |. .|. .. | .||||.
AARNCLVTENNVVKICDFGLA
Kinase 83948.m00059.AA Pkinase_Tyr 188-224 35 0.131305 6.07 Pfam 194-233 (270) Show / Hide 
Range on Protein: 188-224
Range on HMM: 194-233/270
Sequence Identity: 35% (14 aa)

KSDIWSLGVTLYQLAS-GELP-FGATNGSELLYEI-KMGY
|||.|| ||... . . || | .     .|..  | . ||
KSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGY
Kinase 83948.m00059.AA Pkinase_Tyr 237-259 26 1.669365 2.33 Pfam 248-270 (270) Show / Hide 
Range on Protein: 237-259
Range on HMM: 248-270/270
Sequence Identity: 26% (6 aa)

LIKMCLSRNPLKRPSITHVQSCV
|.|.|   .| .||. . .... 
LMKQCWHYDPEDRPTFSEIHEQL