Gene 81132.m00069 (T.vaginalis)

81132.m00069

Species: T.vaginalis
Alias: 81132.m00069, TvagK0829
External Links:
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
81132.m00069.AA Protein None 984 None Fasta, JSON
81132.m00069.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 81132.m00069.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 81132.m00069.AA S_TKc 12-274 16 2.8e-12 3.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-274
Range on HMM: 1-231/231
Sequence Identity: 16% (47 aa)

VKQIRTVGCY---KIFSGVHKTTNERVSLWIVDQDLLKAKFPDKSMRNTFLDNEIASIQAIRKIRHPHVIKVMEYLDKKPEIGFASETIDD-----MDYL
 . .|..|     | . ..|| |...| . |..                 . .||.  .     .||...|  .. .   .. .  | .|      .||.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI

DTNN-------MHPLDASYISYQIAETLSFINAEAHVLHLGLCPQAVMVDKELNVHLMKFEFATPIINAENIEPTPQLLADAKSKNSNNYI-----RPPE
. ..       ... .| .. |||.. | ..    ...|  | |. ...|.  .. .  | .|. .                     . ..     ..||
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------------------TTFCGTPWYMAPE

FLRNYELSP-TSDVFVFGLFLYKCFTGKDLYSSGDPQQILNNLYSYTSNMTGVPEEFKYILQQCLSEQPVQRPVFSRILE-------DPAF
 |     ..  .|.  .|  || ...|. ...  ..|......          ..|.| ....||   | .||    .|.       .| |
VL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81132.m00069.AA SCY1 118-274 15 3.1e-12 38.75 In-house 131-337 (337) Show / Hide 
Range on Protein: 118-274
Range on HMM: 131-337/337
Sequence Identity: 15% (33 aa)

YQIAETLSFINAEAHVLHLGLCPQAVMVDKELNVHLMK---------FEFATPIINAEN-IEPTPQLLA-------------DAK----SKNSNNYIRPP
.|| . ||| . ..|..|...||....|.|     ..          ..| ..| |... ... |.                | |    .... ..  |.
FQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPE

EFLRN------------YELSPTSDVFVFGLFLYKCFTGKDLYSSGDPQQI----------LNNLYSYTSNMTGVPEEFKYI----LQQCLSEQPVQRPV
... .             .... ||.| .|.  .....||..  . . ...          .| . .  . .. .|.| ..      .  |.  | .|| 
YIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQIT-CNSNPYSTFHRYMEQWNAMSH--CWWDHIPKELQEHLGHCYCHLLHQDPTCRPD

FSRILEDPAF
....|... |
PQQFLQHCYF
Kinase 81132.m00069.AA TKL 189-270 19 3.8e-09 29.09 In-house 241-362 (364) Show / Hide 
Range on Protein: 189-270
Range on HMM: 241-362/364
Sequence Identity: 19% (24 aa)

PPEFLR----------------NYELSPTSDVFVFGLFLYKCFTGKDLYS--SGDPQQ---------ILNNLYSYTSNM-------------TGVPEEFK
.|| ||                ..| |. .||. ||. |. ..|..  |.    .|..         ... . ..   .             . .|...|
APEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMK

YILQQCLSEQPVQRPVFSRILE
 ..|.| .. | .|| |..||.
KLMQDCWDHDPEKRPSFQEILK
Kinase 81132.m00069.AA SCY1 21-82 20 1.8e-07 22.05 In-house 1-61 (337) Show / Hide 
Range on Protein: 21-82
Range on HMM: 1-61/337
Sequence Identity: 20% (13 aa)

YKIFSGVHKTTNERVSLWIVDQD--LLKAKFPDKSMRNTFLDNEIASIQAIRKIRHPHVIKVME
.||..|. |.|....|....|      ..|.. .... .||.... . .   ..|||..... .
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLK---RLRHPNILQYIH
Kinase 81132.m00069.AA Ciliate-E2-Unclassified 113-274 15 2.2e-07 21.7 In-house 140-352 (352) Show / Hide 
Range on Protein: 113-274
Range on HMM: 140-352/352
Sequence Identity: 15% (33 aa)

AS-----YISYQIAETLSFINAEAHVLHLGLCPQAVMVDKEL---NVHLMKFEFATPIINAENIEPTPQ-----LLADAKS---KNSNNYIR---PPEFL
|.     .. .|| . |...  . ...|  . |. ...|..    .. .  | ..  ... .|.. | |      . . ..     ..||.    .|| |
AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVL

RNYELSPT----SDVFVFGLFLYKCFTGKDLYSS--------------------GDPQQILNN-LYSYTSNM----TGVPEEFKYILQ----QCLSEQPV
.. . . .    .|.. .|  || . .|.  ...                       |.|... ..   ..      ....| | ...    ..|  .| 
QGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPN

QRPVFSRILEDPAF
.|. |. ||. | |
KRITFEQILNHPWF
Kinase 81132.m00069.AA Ciliate-A3 203-273 31 3.2e-07 19.94 In-house 163-237 (237) Show / Hide 
Range on Protein: 203-273
Range on HMM: 163-237/237
Sequence Identity: 31% (24 aa)

DVFVFGLFLYKCFTGKDLYSSGDPQQILNNLYSYTSNMTGVPEEFKY-----ILQQCLSEQPVQRPVFSRILEDPA
||. ||| ||. || | ..  || .||.|.|  |   .  .  . ..     .. .|| ..| .|| | .|  .  
DVWSFGLILYEMFTCKQIF-KGDQKQIFNQLIHYNNKIDQLLFQERFQDVSKLVIRCLQKDPKKRPDFKQIQTELI
Kinase 81132.m00069.AA TBCK 242-274 30 2.8e-05 14.74 In-house 314-346 (346) Show / Hide 
Range on Protein: 242-274
Range on HMM: 314-346/346
Sequence Identity: 30% (10 aa)

GVPEEFKYILQQCLSEQPVQRPVFSRILEDPAF
. .|. . |. .||.  |  ||     .|.| |
QMCEWLIQIIRKCLQMCPMKRPSPTELMEHPMF
Kinase 81132.m00069.AA MLK 244-272 37 3.4e-05 12.85 In-house 252-280 (280) Show / Hide 
Range on Protein: 244-272
Range on HMM: 252-280/280
Sequence Identity: 37% (11 aa)

PEEFKYILQQCLSEQPVQRPVFSRILEDP
|| .. ..| |    | .|| || ||.  
PEPWAKLMQDCWNQDPHKRPKFSEILQQL
Kinase 81132.m00069.AA TKL-Unique 244-272 37 0.000144 12.23 In-house 262-290 (290) Show / Hide 
Range on Protein: 244-272
Range on HMM: 262-290/290
Sequence Identity: 37% (11 aa)

PEEFKYILQQCLSEQPVQRPVFSRILEDP
|.|.. ..|||   .|.||| |. |..  
PKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 81132.m00069.AA TK 189-272 20 0.000238 9.65 In-house 353-486 (486) Show / Hide 
Range on Protein: 189-272
Range on HMM: 353-486/486
Sequence Identity: 20% (28 aa)

PPEFLR---------NYELSPTSDVFVFGLFLYKCFT-GKDLYSSGDP----------QQILNNL---------------YSYTSNM-TGVP--------
.|| |.         .   .. |||. || ... .|| |.  |  | .          |.....|               | .      . |        
APECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH

------EEFKYILQQCLSEQPVQRPVFSRILEDP
      ||.  ..||| ...| .|| || ..|  
PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 81132.m00069.AA TyrKc 57-272 14 0.000256 -152.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 57-272
Range on HMM: 1-280/280
Sequence Identity: 14% (44 aa)

TFLDNEIAS-------------------------------IQAIRKI--RHPHVIK--------------------VMEYLDKKPEIGFASETIDDMDYL
  |. .. .                               ..  .|.  .||....                    |||| ..     .  .. ..    
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK----

DTNNMHPLDASYISYQIAETLSFINAEAHVLHLGLCPQAVMVDKELNVHLMKFEFATPIINAENIEPTPQL------LADAKSKN-----SNNYIR----
      . |  ....|||.  ...    .. |  |    ..|....                       .       |. .         |  |.|    
----LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENH-----------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEH

------------PPEFLRNYELSPTSDVFVFGLFLYKCFT-GKDLYSS-----GDPQQILNNLYSY--TSNMTG--------VPEEFKYILQQCLSEQPV
            .|| .. .. .. |||. ||  ..  || |.  |.       ..|...... .      .           |.|   | .||  |.| 
KGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

QRPVFSRILEDP
.|| || | |. 
DRPTFSEIHECF
Kinase 81132.m00069.AA LZK 244-272 44 0.000296 10.16 In-house 213-241 (241) Show / Hide 
Range on Protein: 244-272
Range on HMM: 213-241/241
Sequence Identity: 44% (13 aa)

PEEFKYILQQCLSEQPVQRPVFSRILEDP
|| ||  ..||.|  |  || |..||   
PEGFKLLMKQCWSQKPRNRPSFRQILMHW
Kinase 81132.m00069.AA Dicty4 202-226 30 0.00058 9.3 In-house 198-223 (277) Show / Hide 
Range on Protein: 202-226
Range on HMM: 198-223/277
Sequence Identity: 30% (8 aa)

SDVFVFGLFLYKCFTGKDLYS-SGDP
.||. ||. |. ..|....|.  ..|
ADVYSFGIVLWEILTRQEPYQKHHMP
Kinase 81132.m00069.AA Dicty4 243-276 26 0.002232 7.32 In-house 244-277 (277) Show / Hide 
Range on Protein: 243-276
Range on HMM: 244-277/277
Sequence Identity: 26% (9 aa)

VPEEFKYILQQCLSEQPVQRPVFSRILEDPAFNS
.|  .|  .| |... | .|| |. |..    ..
CPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 81132.m00069.AA TKL-Unique 188-218 39 0.117226 1.84 In-house 193-225 (290) Show / Hide 
Range on Protein: 188-218
Range on HMM: 193-225/290
Sequence Identity: 39% (13 aa)

RPPEFLRN--YELSPTSDVFVFGLFLYKCFTGK
..|| ||.  .  |  |||. ||  |. ..|.|
MAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRK