TVAG_114390

Species: T.vaginalis
Alias: TVAG_114390, TvagK1043
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Unique

Sequence

Name Sequence Type Origin Length Description Download
TVAG_114390.AA Protein None 760 None Fasta, JSON
TVAG_114390.kin_dom Protein Kinase Domain None 246 None Fasta, JSON

Protein domain

Protein domains of TVAG_114390.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc TVAG_114390.AA S_TKc 14-248 13 4.7e-07 -73.49 SMART 1-231 (231) Show / Hide
Range on Protein: 14-248
Range on HMM: 1-231/231
Sequence Identity: 13% (38 aa)

VSTGDIL-------VREVTYKPKNEKRILKIYNTRQFQLKQFDRFAIMLDIFHNCKHPFMENIIDFSSKDEKGEQDIAIVIPYKQM--KNLYEEIHINKN
   ....       |. .. |  ...  .|| .         ...   ..| .. .||.  ...|.        ... .|  |      .|.. |. .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGR

D-----IPTDMKALIIYSISCFLSSLHKAG--------GSLPLLDSHGIFFDDNHVLVT----SSSLDPTDDVFGIYPWCSIEKMEKLSSQSSDIFALGA
      .|  . . ..| | | |  .|. |          . |||.        |. ..    .  |   . . |   ... | . . .  ..|. ..| 
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENI-LLDE--------HIKICDFGLARQL---TTFCGTPWYMAPEVL-GYGKCKCDWWSCGC

IAYEMEYKRYPLHDSRDKNEYMRLIKAGERPELDDTPVNRLIFQSMSDQPK---SADEICK--------SLL
| ||| . . | .   . .. ...|.        . ..  .| . .   |.   .| |. .          .
ILYEMLCGYPPFP---QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase TVAG_114390.AA Ciliate-D1 181-199 42 9.3e-05 16.64 In-house 1-19 (19) Show / Hide
Range on Protein: 181-199
Range on HMM: 1-19/19
Sequence Identity: 42% (8 aa)

DIFALGAIAYEMEYKRYPL
||...| | ||| ....| 
DIWSFGCILYEMLFGQPPF

Kinase TVAG_114390.AA SgK495 180-216 43 0.000674 8.23 In-house 98-133 (171) Show / Hide
Range on Protein: 180-216
Range on HMM: 98-133/171
Sequence Identity: 43% (16 aa)

SDIFALGAIAYEMEYKRYPLHDSRDKNEYMRLIKAGE
||..||| . . | |  .|  ||  . |  | ||| |
SDMWALGVVLFTMLYGQFPFYDSIPQ-ELFRKIKAAE

Sel1 TVAG_114390.AA Sel1 325-355 20 0.518416 6.5 Pfam 1-43 (43) Show / Hide
Range on Protein: 325-355
Range on HMM: 1-43/43
Sequence Identity: 20% (9 aa)

PAAQYLLSSFL---ENE--------D-PKR-SRELLAKSAHNGY
| ||| |  ..   . .        | ... ..... |.| .|.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_114390.AA Sel1 388-423 25 1e-06 25.27 Pfam 1-43 (43) Show / Hide
Range on Protein: 388-423
Range on HMM: 1-43/43
Sequence Identity: 25% (11 aa)

VLGMANYG--QMTLIGA--G-CKP-D-EEE-AMKYLLKAVSLGD
. .. |.|  .| . |   | ... |  |. |.... ||  .|.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_114390.AA Sel1 368-387 13 0.759213 5.95 Pfam 23-43 (43) Show / Hide
Range on Protein: 368-387
Range on HMM: 23-43/43
Sequence Identity: 13% (3 aa)

Q-NKNVDE-ARQLFKASADMND
| . . .. |..... .|....
QDD-DYEKEAFYWYQKAAEQGH

Sel1 TVAG_114390.AA Sel1 424-455 13 1.467378 5.0 Pfam 1-43 (43) Show / Hide
Range on Protein: 424-455
Range on HMM: 1-43/43
Sequence Identity: 13% (6 aa)

STSQFIVGSRFM--EQGK----N---D---E-GMKLLLLSGAQGN
. .|. .| ...  ..|.        |   . ..... .. .||.
P-AQYNLG-MYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_114390.AA Sel1 492-528 29 7.1e-09 32.6 Pfam 1-43 (43) Show / Hide
Range on Protein: 492-528
Range on HMM: 1-43/43
Sequence Identity: 29% (13 aa)

PSALVRAA--QILMTGE-GG-VEK-D-EKE-AVELYKKGAEKGV
| |  . .  .....|. || |.. |  .. |...|.| ||.| 
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_114390.AA Sel1 529-564 18 0.00398 13.52 Pfam 1-43 (43) Show / Hide
Range on Protein: 529-564
Range on HMM: 1-43/43
Sequence Identity: 18% (8 aa)

PNACIEYA--NCLINGI--A-VEK-D-RNK-GLSILKLWAEHKY
| |. ...   .. .|.    |.. |  .| ..  ... ||. .
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 TVAG_114390.AA Sel1 569-598 23 6.795416 2.79 Pfam 11-43 (43) Show / Hide
Range on Protein: 569-598
Range on HMM: 11-43/43
Sequence Identity: 23% (8 aa)

MYLYGV-SI-LKE-NKDDKD-ALEFVKKAAHFQY
||..|      .. . |..  |... .|||   .
MYYHGQFGGCVPQDD-DYEKEAFYWYQKAAEQGH

Sel1 TVAG_114390.AA Sel1 694-729 13 0.160533 8.19 Pfam 1-43 (43) Show / Hide
Range on Protein: 694-729
Range on HMM: 1-43/43
Sequence Identity: 13% (6 aa)

KEAIFAMGMMM--MEGN--K-LEK-N-LTD-GAKLVIESARLGL
  | ...||..  ..|      .. . .   ....   .|..| 
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH