Gene 94444.m00155 (T.vaginalis)

94444.m00155

Species: T.vaginalis
Alias: 94444.m00155, TvagK0565
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
94444.m00155.AA Protein None 218 None Fasta, JSON
94444.m00155.kin_dom Protein Kinase Domain None 192 None Fasta, JSON

Protein domain

Protein domains of 94444.m00155.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94444.m00155.AA CAMKL 27-218 34 2e-61 194.7 In-house 1-232 (297) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-232/297
Sequence Identity: 34% (79 aa)

YKVLQVIGSGGFAIIVQAYDTKH-KREVAIKIISRSAAAKNDYLLY------------LEQELRLCTRFN---HPNIV--YEILYEPDT------IMIVM
|......| |.|.    | .... ...|||||| .. . .... .             ...| ..  ..|   ||||.  ||... |..      | .||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYIPKGD---LHFIANNSF---HISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENY--NSKIIDFGLS-----C-ENPNH-LVTICGTENYM
||.. |.   ...| ..      .. .   ..   |. ..||.||.||.|||||..|||||||   | ||||||.|     |  .|.. | | ||. .||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEILIN-SESYNGKKADIWSFGVLLYALMNG
||||.    ..|.|.|.|||| ||.|||.. |
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCG
Kinase 94444.m00155.AA CAMK 32-218 20 9.7e-58 184.29 In-house 1-330 (425) Show / Hide 
Range on Protein: 32-218
Range on HMM: 1-330/425
Sequence Identity: 20% (68 aa)

VIGSGGFAIIVQAYDTKHK------------REVAIKIISRSAAAK------------------------NDYLLY-LEQELRLCTR-------FNHPNI
..|.|.|..   ..... .            ..||||||... . .                        ... .  ...|.... .        .||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VYEILYE-----------------------PDTIMIVM---EYIPKG----D-LHFIANN--------------SFHISCKLKIQIAEGILNGLNYLHSR
.   |||                       .. . .||   ||.. |    | . .|  .              ..... .   ..   |. ...|.||.
IK--LYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

GICHRDIKLDNILLDEN-----------------YNSKIIDFGLSCE-NPNH-------------------------LVTICGTENYMA-PEILINS---
.|.|||.|..|||||.|                 .| ||||||.... .|..                         . | |||  ||| ||.|  .   
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------ESYNGKKADIWSFGVLLYALMNG
         . | |.|.|.|| ||.||..  |
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCG
Pkinase 94444.m00155.AA Pkinase 27-218 36 6.2e-57 200.26 Pfam 1-208 (293) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-208/293
Sequence Identity: 36% (76 aa)

YKVLQVIGSGGFAIIVQAYDTKHKREVAIKIISRSAAAK--NDYLLYLEQELRLCTRFNHPNIV--YEILYEPDTIMIVMEYIPKG----DLH-FIA-NN
|.....||||.|.   .... .  ..||.|||... . .  . ... | .|...  |.||||||  |.. ...| | .|||| ..|    ||. .|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

SFHI--SCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENYNS----KIIDFGLSC---ENPNHLVTICGTENYMAPEILINSESYNGKKADIWS
.  .  | .  . ..  || ||.|.||.||.|||.|..|||.|.|..     ||.||||..   . .|.. |.||| .|||||..  . .| |.|.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIR-GGQYYGPKVDMWS

FGVLLYALMNG
.|..|| ...|
CGCILYEMLCG
Kinase 94444.m00155.AA Ciliate-E2-Unclassified 27-218 26 8.4e-52 177.96 In-house 1-266 (352) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-266/352
Sequence Identity: 26% (72 aa)

YKVLQVIGSGGFAIIVQAYDTKHKREV-AIKIISRSAAAKNDYLLY----LEQELRLCTR------------------FNHPNIVYEILYE--PDTIMIV
||....||.|||... .... |.| .. |.|... .   |  . ..    . ...... .                  ..||.||... ..   ..| ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYIPKGDLHFIANNSFH-----------------ISCKLKI-----QIAEGILNGLNYLHSRG-ICHRDIKLDNILLDENY---NSKIIDFGLSC---E
|||.. |||... ... .                 ....  .     ...  ||.||.|||. . |.|||||..|||.|.|    . ||||||.|    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

N---------------PNHLVTICGTENYM----APEILINSESYNG--KKADIWSFGVLLYALMNG
|               .... |.||| |||    |||.| . . ..   .|.||||.||.||... |
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG
Kinase 94444.m00155.AA TKL 33-216 23 2.7e-50 173.39 In-house 1-283 (364) Show / Hide 
Range on Protein: 33-216
Range on HMM: 1-283/364
Sequence Identity: 23% (69 aa)

IGSGGFAIIVQAYDTKHK--------REVAIKIISRSAAAKND------------------------YLLYLEQELRLCTRFNHPNIVYEIL---YEPDT
||||||... ...   .         ..||.|....    ...                        .   .|.|.... |..|||||  .    ..|..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------IMIVMEYIPKGD-LHFIANNSFHISCKLKIQIAEGILNGLNYLHS--------RGICHRDIKLDNILLDENYN--------------S
            ..|||||.|.|. ||..          .....| .|  |.|||||        ..| |||.| .|||.|||..               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KIIDFGLSCENPNH----------------------LVTICGTENYMAPEILINSESYNG--------------KKADIWSFGVLLYALM
|| ||||| .. ..                      . |.||| ..||||.| ... |.               .|.|..|||..|. ..
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEIL
Kinase 94444.m00155.AA Ciliate-E2 27-218 27 7.3e-49 165.86 In-house 1-292 (365) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-292/365
Sequence Identity: 27% (81 aa)

YKVLQVIGSGGFAIIVQAYDTKHKREVAIKIISRSA---------AA---------KNDYLLYLEQELRLCTRFN----------------HPNIV--YE
||....||.|.|... .. . | ....|||||             ..         |.. . ...||.... . |                ||||.  ||
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

ILY--EPDTIMIVMEYIPKGDLHF-IANN---SFHI-------SCKLKIQIAEGILN---------------GLNYLHSRG-ICHRDIKLDNILLDENYN
  .    ..| .||||.  |||   | ||   ..|.       ..|  ..| . ||.               .|.||||.. |.|||||..|||.     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

SKIIDFGL------------------SCENPN-----------------HLVTICGTENYMAPEILINSESY-------NGKKADIWSFGVLLYALMNG
 |||||||                   . . .                    ||||| .||||||| . . .        ..|.||||.||.|| .. |
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG
Kinase 94444.m00155.AA LISK 32-212 29 8.7e-44 140.03 In-house 1-229 (296) Show / Hide 
Range on Protein: 32-212
Range on HMM: 1-229/296
Sequence Identity: 29% (68 aa)

VIGSGGFAIIVQAYDTKHK---REVAIKIISR--SAAAKNDYLLYLEQELRLCTRFNHPNIV--YEILYE-PDTIMIVMEYIPKGDLH-FIANNSF---H
.||.|.|. ... .   |.   ...||| |.|    . ...|. ....|. .  .. |||||  . ..|.  . ..|| |||  |||| .......   .
EIGKGFFGKVYKGT---HRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIP

ISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDEN----YNSKIIDFGLS----CEN---------------------------------PNHLV
.. .... || .|  |. ||||..|.||| |  |.|..||    .. |..|||.     |||                                 ..   
LPWPQRVKIALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TICGTENYMAPEILINSESYNGKKADIWSFGVLL
|||||.. ||||.|.  .||.  ..|. |||..|
TICGTPYWMAPEMLLG-QSYD-ESCDVFSFGIVL
Kinase 94444.m00155.AA ULK 27-218 25 6.1e-43 148.98 In-house 1-248 (324) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-248/324
Sequence Identity: 25% (64 aa)

YKVLQVIGSGGFA-IIVQAY--DTKH-KREVAIKIISRSAAAKNDYL-------LYLEQELRLCTRFN---HPN--IV--YEILYEP--DTIMIVMEYIP
| . ...|.| |.    ...  .|.. .  ||.|.|...   |. ..         |..| ..   ..   |||  ||  |......  . | |.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

KGDLHFIANNSFH---------ISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENYNSK------------IIDFGLSCE-NP-----NHLVT
 |||  . ..  .         .| .  ||.   |.||. .||...| |||||..|||. ..  ..            | |||..   .      . . |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

IC------GTENYMAPEILINS--ESYNG-KKADIWSFGVLLYALMNG
..      ||  ||||.|| .   .   . .|.||||.|...| .  |
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG
Kinase 94444.m00155.AA ULK 27-218 25 4.7e-42 144.62 In-house 1-252 (329) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-252/329
Sequence Identity: 25% (65 aa)

YKVLQVIGSGGFAIIVQAYDTKHK----REVAIKIISRSAAAKNDYLLY-------LEQELRLCTRFN--------HPNIV--YEILYEP--DTIMIVME
| . ...|.| |.   .... | |      ||.|.|...   .. .. .       |..| ..  . .        |||||  |......  . | |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YIPKGDLHFIAN----------NSFHISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENYNSK------------IIDFGLSCE-NPN-----
| . |||  . .          .  ..| .  ||.   ||||. .||...| |||||..|||....  ..            | |||..   . .     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

HLVTIC------GTENYMAPEILINS--ESYNG-KKADIWSFGVLLYALMNG
 ..|        ||  ||||.|| .   .   . .|.||||.|...| .  |
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG
Kinase 94444.m00155.AA MARK 132-218 53 1.1e-40 130.85 In-house 113-202 (262) Show / Hide 
Range on Protein: 132-218
Range on HMM: 113-202/262
Sequence Identity: 53% (49 aa)

ILNGLNYLHSRGICHRDIKLDNILLDENY--NSKIIDFGLSCEN-PNH-LVTICGTENYMAPEILINSESYNGKKADIWSFGVLLYALMNG
|. ..||.||..|.|||||..|||.|||   | ||||||.| .  |.  | | |||  ||||||. ... |.|.|.|||| ||.||..  |
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIF-LKKPYDGPKVDIWSLGVVLYFMVCG
Kinase 94444.m00155.AA QIK 27-218 32 8.2e-39 135.27 In-house 1-214 (272) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-214/272
Sequence Identity: 32% (71 aa)

YKVLQVIGSGGFAIIVQAYDTKHKREVAIKIISRSAAAKNDYLLYLEQELRLCTRFNHPNIV--YEILYEPDTIMIVMEYIPKGDLHFIANNSFH-----
| . . || | ||..  |     | .|||||| .|.  . ..|  .. |  .  . .||.|.  |...   | . ||.|| . |..    ..  .     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDE-ENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------ISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENYNSKIIDFGLS--CENPNHLVTICGTENYMAPEILINSESYNGKK
               .. .   ..   |. .  |.|.|.| |||.|  |||||.| | ||.|||.|   ..   | | ||.  | |||..   | |.| |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKE-YDGPK

ADIWSFGVLLYALMNG
.|||| ||.||.|  |
VDIWSMGVVLYVLVCG
Kinase 94444.m00155.AA S_TKc 27-218 28 3.2e-36 127.59 SMART 1-220 (231) Show / Hide 
Range on Protein: 27-218
Range on HMM: 1-220/231
Sequence Identity: 28% (70 aa)

YKVLQVIGSGGFAIIVQAYDTKHKREVAIKIISRSAAAKNDYLLYLEQELRLCTRFNHPNIV--YEILYEPDTIMIVMEYIPK--GDLHFIANNSFH---
|..|..||.|.|.   .....| .|.||||||.            ...|.... . .|||||  |.. .. | . .||||..   |||. .  .  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENYNSKIIDFGLSCENPNHLVTICGTENYMAPEILINSESYNGKKADIWSFGVLLYALM
   ..      ..  |...|.|.||.||.|||.| .||||||  . ||.||||...      |.||| .|||||.|    .|...|.|.||.|..|| ..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

N-----------------------------------------G
                                           
CGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQ
Kinase 94444.m00155.AA Pkinase_Tyr 27-170 28 1e-15 53.82 Pfam 1-158 (270) Show / Hide 
Range on Protein: 27-170
Range on HMM: 1-158/270
Sequence Identity: 28% (46 aa)

YKVLQVIGSGGFAIIVQAYDT----KHKREVAIKIISRSAAAK-NDYLLYLEQELRLCTRF-NHPNIV--YEILY-EPDT--IMIVMEYIPKGDLH-FIA
 . ....|.| |  ..... .    ..| .||.|..  .|  . | ..  . .|... . . .|||||  | . . . .   |.||||| |.|||. .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

NN---SFHISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENYNSKIIDFGLS
..     ... | ..|..  | .|..||.|... |||.   |.|..||   || ||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 94444.m00155.AA MARK 27-111 27 4.6e-14 42.52 In-house 1-90 (262) Show / Hide 
Range on Protein: 27-111
Range on HMM: 1-90/262
Sequence Identity: 27% (25 aa)

YKVLQVIGSGGFAIIVQAYDTKHKREVAIKIISRSAAAKNDYLLYLEQELRLCTRFNHPNIV--YEILY--EPDT-IMIVMEYIPKGDLH
||.|..|| |..|    | ... .|.|||||. .    ..  .  .. |...  . .||||.  ...    .. . | ..|||...|.|.
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELY
Kinase 94444.m00155.AA TyrKc 27-216 20 1.4e-13 -2.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 27-216
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

YKVLQVIGSGGFAIIVQAYDTKHKREVAIKIISRSAAAKNDYLLYLEQELRLCTRF--NHPNIV--YEILYEP-------DTIMIVMEYIPKGDLH-FIA
 . ....|.| | .....  .   ..||.| .  .|      .  . .|.|. ...  .|||||  | .  ..       . .|||||| |.|||. .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NNSFHISCKLKIQIAEGILNGLNYLHSRGICHRDIKLDNILLDENYNSKIIDFGLSCENPNH-------LVTIC----GTE-----NYMAPEILINSESY
..  ... | .....  | .| .||||... |||.   |.|..||.  || ||||| .  ..        .       |.        |||| .     |
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI----NY

N--GKKADIWSFGVLLY------------------------------------AL-------------------------------------M
.    | |.|||||...                                    .                                      .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 94444.m00155.AA Pkinase_Tyr 187-213 44 0.039148 7.85 Pfam 181-205 (270) Show / Hide 
Range on Protein: 187-213
Range on HMM: 181-205/270
Sequence Identity: 44% (12 aa)

MAPEILINSESYNGKKADIWSFGVLLY
|||| . ...     | |.||||||..
MAPECINYGK--FTTKSDVWSFGVLMW