Gene 86673.m00347 (T.vaginalis)

86673.m00347

Species: T.vaginalis
Alias: TvagK0797, 86673.m00347
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: LKB

Sequence

Name Sequence Type Origin Length Description Download
86673.m00347.AA Protein None 376 None Fasta, JSON
86673.m00347.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 86673.m00347.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 86673.m00347.AA S_TKc 33-290 28 2.1e-73 251.09 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-231/231
Sequence Identity: 28% (79 aa)

YLFLKKIGNGAFSNVYLAIDQNTKEKYAIKKFKLSELQHIENGVSQLEREISLMRRYSHNNILKLFEVLHNTEKDIVYLVIEYANC--GSLFDLINQPIP
| .|.||| |||. ||.... .|....|||. |            ...|||.....  | || ||..| ..   | .|.| ||..   |.|||.| .  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

------LQDNYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSDGRAILADFGVGHSFQSTEMVVGSPAYQAPEALTDGDCGIQSSSPAKEDVWSLGV
      .    ......||..||.|.|..| .| |.||.|||. .  .  ..|||.   .     ..|.| | ||| |        . ...| |.||.|.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGC

TLFQTEYQQIPYDGETVFEIIRNIKSTTLQYPEGANPEIEQVMRMMLAVDPVKRATVDELLK-------SPFF
.|.   . . |..  ........|.           ||  . .| .| .|| || |. |.|.        |.|
ILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 86673.m00347.AA Pkinase 33-290 25 2.3e-70 244.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-293/293
Sequence Identity: 25% (77 aa)

YLFLKKIGNGAFSNVYLAIDQNTKEKYAIKKFKLSELQHIENGVSQLEREISLMRRYSHNNILKLFEVLHNTEKDIVYLVIEYANCG----SLFDLIN--
| ...||| |.|. ||......| ...|.|..|...  . ..    . .||..|.| .| ||..|... ..  || .|.| ||...|    .|||.|   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

QPIPL--QDNYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSDGRA----ILADFGV-----GHSFQSTEMVVGSPAYQAPEALTDGDCGIQSSSPA
.  ..  ... ..... |||..|.|.|..| .| |.||.||||...|       ..|||.       . . .  ..|.| | ||| .       ..  . 
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQYYGP

KEDVWSLGVTLFQTEYQQIPYDGE------TVFEIIRNIKSTTLQYPEGAN---------------------PEIEQVMRMMLAVDPVKRATVDELLKSP
| |.||.|..|..    . |..|.      .  ..|..|... | ...                        .|  .... .|..|| || | ...|..|
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

FF
.|
WF
Kinase 86673.m00347.AA CAMK 38-290 20 2.5e-64 205.9 In-house 1-425 (425) Show / Hide 
Range on Protein: 38-290
Range on HMM: 1-425/425
Sequence Identity: 20% (86 aa)

KIGNGAFSNVYLAIDQNTK------------EKYAIKKFKLSELQ------------------------HIENGVSQLEREISLMRR-------YSHNNI
..| |.|. |.|.|. ||.            .|.|||  . . |.                        . ..   ...|||..|..        .| ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKLFEVLHN-----------TEKD-------IVYLVI---EYANCG----SLFDLINQP---------------IPLQDNYVCSIFHQILEALQYLHNNG
.||.||  .           | ..        .|.|    ||.  |     ||| | .                  ..   .. .|.||..|..|.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

MVHQDIKPSNILIKSD-----------------GRAILADFGVGHSFQS---------------------------TEMVVGSPAYQA-PEALTD-GDCG
 || |.|| |||. ..                 .   ..|||    |..                            . ..|.|.| | || |   | | 
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

IQSS--------SPAKEDVWSLGVTLFQTEYQQIPYDGE-------------TVFEIIRNIKSTTLQYPEGANP------------------------EI
 | .         . | |.||.|| |.       |..|.             .  |. ..|..   ..|.   .                        | 
MQ-NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

EQVMRMMLAVDPVKRATVDELLKSPFF
 .  | || ||| ||.|... |. |..
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 86673.m00347.AA CAMKL 33-290 28 4e-63 200.23 In-house 1-297 (297) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-297/297
Sequence Identity: 28% (85 aa)

YLFLKKIGNGAFSNVYLAID-QNTKEKYAIKKFKLSELQHIENGVSQ-----------LEREISLMRRYS---HNNILKLFEVLHNTEK----DIVYLVI
| ..| .| |.|. | ||.. ..|.||.|||  . . .. ...  .            ..|||..|.. .   | || ||.||. . |.    . .||| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYANCGS--LFDLI--NQP--IPLQDNYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSDG--RAILADFGVG-----H---SFQSTEMVVGSPAYQ
||.  |.  ||| |  .     ... .  . .| ||..|..|.|..| || |||| |||. ..|   . ..||| .     .   . |  ..  |||.|.
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEALTDGDCGIQSSSPAKEDVWSLGVTLFQTEYQQIPYDGET--------VFEIIRNIKSTTLQYPEGANP-EIEQVMRMMLAVDPVKRATVDELLKSP
||| . ..    ..    | |.||.||.|.   . . | |..|        . .  . |...  ..|    . . ..  | || |.| ||.|...... |
APEIFQGN---NKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHP

FF
..
WM
Kinase 86673.m00347.AA CAMKK 33-290 20 6e-62 195.22 In-house 1-396 (396) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-396/396
Sequence Identity: 20% (81 aa)

YLFLKKIGNGAFSNVYLAIDQNT-KEKYAIKKFKL----SELQH----------------------IENGVSQLEREISLMRRYSHNNILKLFEVLHNTE
| ..|.||.|.|  | ||.. .. . .|||| |.       |.                       . |. .....||. |..  | || ||.||. ...
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

KDIVYLV-IEYANCGSLFDLI--NQ-----------------------PIPLQDNY---------------------VCSIFHQILEALQYLH-NNG---
 | .|.| .||.. |.....   .|                       .  .. ..                       ..| ... .|.||| ...   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------MVHQDIKPSNILIKSDG---RAILADFGVGHSF-QSTEM--------------VVGSPAYQAPEALTDGDCGI-----------
                ..| ||||.||||...|   .. .||||| |.| ....                .| ||..|||...... .            
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-QSSSPAKEDVWSLGVTLFQTEYQQIPYDGETVFEIIR---NIKSTTLQYPE-------------GANPEIEQVMRMMLAVDPVKRATVDELLKSPFF
  .. .|  |.|.|||||.   . ..|. ... ... .    ||   ...||               ...   .   ||  .| || |...... |..
IYCGKAA--DIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIKVHPWV
Kinase 86673.m00347.AA Ciliate-E2 33-290 21 1.1e-57 196.62 In-house 1-365 (365) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-365/365
Sequence Identity: 21% (84 aa)

YLFLKKIGNGAFSNVYLAIDQNTKEKYA----------------IKKFKLSELQHIENGVSQLEREISLMR----------------RYSHNNILKLFEV
| |.||||.|.|. ||.. . ......|                 |...    . ..|.. |...||..||                . .|.||.|..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LHNTEKDIVYLVIEYANCGSLFDLIN------------QPIPLQDNYVCSIFHQILE---------------ALQYLHNNG-MVHQDIKPSNILIKSDGR
  .. .. .||| ||.. |.|||.|.            .  .. .. .. |. |||.               ||.|||...  .| ||||.|||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

AILADFGV------------------------GHSFQSTEM-----------VVGSPAYQAPEALTDGD---------CGIQSSSPAKEDVWSLGVTLFQ
  ..|||                           | ... |           ..|.| |.||| |  ..          . ..      |.|||||.|..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKC------DIWSLGVILYE

TEYQQIPYDGETVFEIIRNIKSTTLQYP----------------EGANPEIE--QVMRM----MLAVDPVKRAT-VDELLKSPFF
  . . |.        ...||   ...|                .  . . |  . ..     || .|| || |  ...|. |.|
MLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 86673.m00347.AA Ciliate-E2a 33-290 30 2.1e-56 164.55 In-house 1-275 (275) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-275/275
Sequence Identity: 30% (87 aa)

YLFLKKIGNGAFSNVYLAIDQNTKEKYAIKKFKLSELQHIENGVSQLEREISLMRRYSHNNILKLFEVLHNTEKDIVYLVIEYANCGSLFDLINQPI-PL
| |.||||.|.|  ||||   .|....|.|||.   .. ...|  ....||..||. .| ||.||.||  .  ..  ||| || . |.|.| |.|     
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYED--ENNYYLVMEYCEGGELYDKIKQCKRFF

QD-NYVCSIFHQIL-EALQYLHNNGMVHQDIKPSNILIK---SDG----RAILADFGVGHSF---QS--TEMVVGSPAYQAPEALTDGD------CGIQS
.  ...|.|  |.| ..|.|.|... .| |.|| |||.|   ...      ...||| .  .   .       .|.| | ||| |   .      .. . 
EEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC

SSPAKEDVWSLGVTLFQTEYQQIPYDGETVFEIIRNIKSTTLQYPEGA-----NPEIEQVMRMMLAVDPVKRATVDELLKSPFF
      |.||.|| ..   . . |..|.|. ||. ..|   ...           |  . |. || .|| || |  ..|..|.|
------DMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 86673.m00347.AA CAMK-Unique 33-290 21 2.3e-51 167.72 In-house 1-363 (363) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-363/363
Sequence Identity: 21% (77 aa)

YLFLKKIGNGAFSNVYLAIDQNTKEKYAIKKFKLSELQHIENGV----------------SQLEREISLMRRYSHNNILKLFEV---LHNTEKD------
| ... ||.|.|. || ..|. |. |.|.|..|.   . . . .                 .|.||...... .|.||.||...   .  ..|       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------IVYLVIEYANCGSLFDLINQ--------------------PIPLQD--NYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSDGR-----
          |.| ||...| |||.|..                     ...    . .|.|. ..|.|. |.|... || |.|. ||.... .      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------AILADFGVGHSFQSTEMV------VGSPAYQAP-------------EALTDGDCGIQSSSPAKEDVWSLGVTLFQTEYQQIPYDGETVF
             |.|||    ... .|       .|.| | ||             ... ...|  | .|||  | |||||...       | |.|.  
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPA-SDIWSLGVIMYYMLCGCPPFDCECED

--------EIIRNIKSTTL-QYPEGANPE-------IEQVMRMMLAVDPVKRATVDELLKSPFF
        ||...|..  .  ... ..           ..    . |||..| .  |||.....
RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 86673.m00347.AA ULK 33-290 23 2.2e-50 173.68 In-house 1-324 (324) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-324/324
Sequence Identity: 23% (77 aa)

YLFLKKIGNGAFS-NVYLAIDQNT---KEKYAIKKFKLSELQHIENGVS------QLEREISLMRRYS---HNN--ILKLFEVLHNTEKDIVYLVIEYAN
|   ...| |.|   || .....|   ....|.|.  ..... ..|         .|..||..|.      |.|  | ||.... ..  . .|.. || |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

CGSLFDLINQPIP---------LQDNYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSD------------GRAILADFGVGHSFQS-----TEM--
.| |...|..  .         |  . . ..|.||......||... .| ||||.||||. .            |.. .|||| . ....     . .  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

------VVGSPAYQAPEALT-DGDCGIQSSSPAKEDVWSLGVTLFQTEYQQIP---YDGETVF----EIIRN-------IKSTTLQYP-----EGANPEI
      ..|.| | ||. |   |  . .  . .| |.||||. ...  | . |   .  .. .    . |.|       || . .|.|         ||.
CVNEKRIKGTPLYMAPQILQGQG--EQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPEC

EQVMRMMLAVDPVKRATVDELLKSPFF
..  | || .|. .| . .|... |.|
KDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 86673.m00347.AA Ciliate-E2-Unclassified 33-290 21 4.2e-50 171.98 In-house 1-352 (352) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-352/352
Sequence Identity: 21% (77 aa)

YLFLKKIGNGAFSNVYLAIDQNTKEKY----AIKKFKLSELQHIENGVSQLERE-ISLMRR----------------YSHNNILKLFEVLHNTEKDIVYL
| ..|.||.|.|. ||.... ..| .|     .||..    . |.|   .. .| . ....                ..|...... .. . . |. .|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VIEYANCGSLFDLINQPIP-----------------LQDNYVC-----SIFHQILEALQYLHNNG-MVHQDIKPSNILIKSDG---RAILADFGVGH---
| ||.. |.|.. |..                    .... ..      .| |||..|.||| ..  .| ||||.|||....|   .  ..|||      
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

----------------SFQSTEMVVGSPAYQ----APEALTDGDCGIQSSSPAKEDVWSLGVTLFQTEYQQIPYDGETVFE----------------IIR
                ..| .  ..|.| |.    ||| |     . ...   | |.||||| |..  ... |.....  .                ...
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKA--YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

NIKSTTLQYPE--------GANPEIEQVMR----MMLAVDPVKRATVDELLKSPFF
|||   .|.|.        . .|| .   .     || ..| || | ...|. |.|
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 86673.m00347.AA STE 33-290 23 9.3e-50 171.63 In-house 1-359 (359) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-359/359
Sequence Identity: 23% (85 aa)

YLFLKKIGNGAFSNVYLAIDQ------NTKEK---------YAIKKFKLSELQHIENG--------------VSQLEREISLMRRYS--HNNILKLFEV-
. ...|||.|||  ||.|..        |.|.         .|||. .|.. .  .                . |...||..|....  | || | .   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

LHNTEK----DIVYLVIEYANCGSLFDLIN------QPIPLQ--------DNYVCSIFHQILEA-LQYLHNNGMVHQDIKPSNILIKSDGRAILADFGVG
... ..    | .... || . ||| |.|.      .| ...         . .. | .|||.. |.|||... .| ||||.|||.     . |.|||| 
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

HSFQS--------------------TEMVVGSPAYQAPEALTDGDCGIQ-SSSPAKEDVWSLGVTL---FQTEYQQIP-YDGETVFEIIRNI--------
 ....                    .  .||.| . ||| .. ...|   .   .| |.|||| |.      ..     .. .  |.|..|.        
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQ

------KSTTLQY-----------------PEGANPEIEQVMRMMLAVDPVKRATVDELLK--SPFF
      .. .|.                  |.   ||  . ..  |  || ||.|...|||   ||.
LCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 86673.m00347.AA ULK 33-290 25 5.3e-48 165.66 In-house 1-329 (329) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-329/329
Sequence Identity: 25% (83 aa)

YLFLKKIGNGAFSNVYLAIDQNTK----EKYAIKKFKLSELQHIENGVS------QLEREISLMRRYS----HNN----ILKLFEVLHNTEKDIVYLVIE
|   ...| |.|  || .....||    ||.|.|.  ..... ..|         .|..|| .|..      |.|    | ||.... ..  . .|.. |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YANCGSLFDLINQPIP----------LQDNYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSD------------GRAILADFGVGHSFQS------
| | | |...|..  .          |  . . ..|.|||.....|| .. .| ||||.||||. .            |.. .|||| . ....      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-TEMVV------GSPAYQAPEALT-DGDCGIQSSSPAKEDVWSLGVTLFQTEYQQIP---YDGETVF-----EIIRN-------IKSTTLQYP-----EG
 .   |      |.| | ||. |   | .  .... .  |.||||. ...  | . |   .  .. .     . |.|       ||.. ||.|       
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKC--DIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

ANPEIEQVMRMMLAVDPVKRATVDELLKSPFF
  ||...  | || .|. .| . .||.. |.|
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 86673.m00347.AA TyrKc 33-290 23 3.8e-16 38.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-290
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

YLFLKKIGNGAFSNVYLAIDQNTKEKYAIKKFKLSELQHIENGVSQLEREISLMRRY--SHNNILKLFEVLHNTEK-----DIVYLVIEYANCGSLFDLI
  ..||.|.|||  ||...     .. |.|. | .        .  . ||...|...  .| ||..|. |    .      . ...| ||.  |.| | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

NQPIP-LQDNYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSDGRAILADFGVGHSFQST-------EMVV-----GSP-----AYQAPEALTDGDC
  . | |.    .|. .|| .  .||| .. .| |.   |.|.......  .|||      .        .. .     |.         |||.. .| .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

GIQSSSPAKEDVWSLGVTLF-QTEYQQIPYDG-----ETVFEIIRNIKST-TLQYPEG--------ANPEIEQVMRMMLAVDPVKRATVDELLKSPFF
 ..|      |||| ||...    | | || |      . .|.|...|.   .  |.         . .|. |.|..  . || .| |  |.    .|
TTKS------DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 86673.m00347.AA Pkinase_Tyr 33-179 28 1.6e-09 32.89 Pfam 1-156 (270) Show / Hide 
Range on Protein: 33-179
Range on HMM: 1-156/270
Sequence Identity: 28% (45 aa)

YLFLKKIGNGAFSNVYLAIDQ----NTKEKYAIKKFKLSELQHIENGVSQLEREISLMRRY-SHNNILKLFEVLH-NTE-KDIVYLVIEYANCGSLFDLI
  |.||.| ||| .||...      ||| . |.|.       | .|    . ||...|. . .| ||..|  |     | .  .|.| ||. .|.| |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

NQ----PIPLQDNYVCSIFHQILEALQYLHNNGMVHQDIKPSNILIKSDGRAILADFG
 .    . ||     ... .|| ....||......| |.   |.|..... .  .|||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 86673.m00347.AA Pkinase_Tyr 198-227 36 3.698087 1.16 Pfam 182-205 (270) Show / Hide 
Range on Protein: 198-227
Range on HMM: 182-205/270
Sequence Identity: 36% (11 aa)

APEALTDGDCGIQSSSPAKEDVWSLGVTLF
|||.. .| . ..|      |||| ||...
APECINYGKFTTKS------DVWSFGVLMW