Gene 90756.m00167 (T.vaginalis)

90756.m00167

Species: T.vaginalis
Alias: TvagK0885, 90756.m00167
External Links:
Annotation:

Classification

Group: Other
Family: WEE
Subfamily: WEE-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
90756.m00167.AA Protein None 191 None Fasta, JSON
90756.m00167.kin_dom Protein Kinase Domain None 187 None Fasta, JSON

Protein domain

Protein domains of 90756.m00167.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90756.m00167.AA WEE 3-178 25 5.6e-37 121.61 In-house 81-297 (297) Show / Hide 
Range on Protein: 3-178
Range on HMM: 81-297/297
Sequence Identity: 25% (55 aa)

YLQMELAEFGS-----IR---PRYLK-LPTQEIWKVFAHIISAVAYIHSK-SYMHLDISPSNILQCSHP-----------------IVGNIYKLADFGTT
|.|||. . ||     .    ... . || ..||... .|. ....|||. . .|.|| |.||. ...                     ...|..|||  
YIQMEYCNGGSNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFN-MMCKIGDFGHV

LPVD----NFKEDFEGAGPYVSPETLQ-YPNTEYPVSSPTDIFSLGVVLLEMVTRKYAPRAFPAYGDLRSG-------KYD----FSKIPKEF-SFISQM
  ..    |.... || ..| .||.|| | .  .  ..  |||||| ...|.....  |.  ..  ..|.|       .      . .|..|. ..| .|
TDMNSNNNNPHQEQEGDSRYMAPEILQGYYHYTHLYKA--DIFSLGITIYELACNMDLPKNGDWWHQIRQGDLSFDKNQIPFPEFDNIISQELKQLIKWM

LAPNPMERPTAEQLLKLDGV
. |.|  |||..|||. . .
MHPDPEQRPTCQQLLQHPVL
Kinase 90756.m00167.AA Ciliate-E2 3-174 20 5.9e-25 82.58 In-house 110-361 (365) Show / Hide 
Range on Protein: 3-174
Range on HMM: 110-361/365
Sequence Identity: 20% (54 aa)

YLQMELAEFGSIRP---------------RYLKLPTQEIWKVFAHIIS---------------AVAYIHSKS-YMHLDISPSNILQCSHPIVGNIYKLAD
|| ||... |. .                  ...  .|| .....|..               |. |.|||   .| || |.|||           |..|
YLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKIID

FGTTLPVDNFKEDFE----------------------------------GAGPYVSPETLQYPN-----TEYPVSSPTDIFSLGVVLLEMVTRKYAPRAF
||.   .|.. ..                                    |  .|..|| |.. .     .. . .   ||.||||.| ||.. |.     
FGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

PAYGDLRSGKYDFS-------------------KIPKE-FSFISQ----MLAPNPMERPT-AEQLLK
  .     .|.||.                   |...|   .|..    ||  .| .|.| .||.|.
--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN
Kinase 90756.m00167.AA Pkinase 3-178 20 2e-21 76.81 Pfam 76-293 (293) Show / Hide 
Range on Protein: 3-178
Range on HMM: 76-293/293
Sequence Identity: 20% (46 aa)

YLQMELAEFG----SIRPRYLK------L--PTQEIWKVFAHIISAVAYIHSKSYMHLDISPSNILQCSHPIVGNIYKLADFGTT----LPVDNFKEDFE
|. ||..| |    .   .|..      .  . .|. ...  |.....|.||.. .| |. |.|||  ... .. . |..|||      .  .    .| 
YMVMEYCEGGLYVMDLF-DYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC

GAGPYVSPETLQYPNTEYPVSSPTDIFSLGVVLLEMVTRKYAPRAFPAYGD--------------LRSGKYDFSKI-----------------------P
|  .|..|| ..   .  . ... |..|.|..| ||....     .| .|.               ......|.                         .
GTPWYMAPEVIR---GGQYYGPKVDMWSCGCILYEMLCGR-----PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSE

KEFSFISQMLAPNPMERPTAEQLLKLDGV
   .||. .|...| .||||||.|. . .
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 90756.m00167.AA TKL 6-176 15 7.4e-14 46.28 In-house 117-364 (364) Show / Hide 
Range on Protein: 6-176
Range on HMM: 117-364/364
Sequence Identity: 15% (40 aa)

MELAEFGSIRPRYLKLPTQEIWKVFAHIISAVAYIHS--------KSYMHLDISPSNILQCSH----------PIVGNIYKLADFGTTLPVDNFKEDFEG
||... || . ...    . . .    | ....| ||        .   | |. ..|||  ..          |.     |..|||.   ... ...  .
MEYCPGGSLLHYLH---WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDT

-------------------AG---PYVSPETLQ----YPN--------TEYPVSSPTDIFSLGVVLLEMVTRKYAPRAFPAYG--------DLRSGKYDF
                    .    . .|| |.    |..         ... |  .|..| |.|| |..||.   . .| .         .  .. .| 
MTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDK

S---KIP------------KEF-----SFISQMLAPNPMERPTAEQLLKLD
.    ||            . .     . . .  ...| .||.....||  
GLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 90756.m00167.AA DRAK 33-118 36 1.2e-13 38.2 In-house 108-190 (259) Show / Hide 
Range on Protein: 33-118
Range on HMM: 108-190/259
Sequence Identity: 36% (32 aa)

IISAVAYIHSKSYMHLDISPSNILQCSHPIVGNIYKLADFGTTLPVDNFKE--DFEGAGPYVSPETLQYPNTEYPVSSPTDIFSLGVV
|  .| | |...  |||  | |||  |  . . | |. |||    . |  |  .  |   || || |.|     |..  ||. | ||.
ILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDI-KICDFGMSRYICNGEEVREIMGTPDYVAPEILNY----DPITMATDMWSIGVL
Kinase 90756.m00167.AA CAMK2 33-178 30 5.7e-13 40.05 In-house 107-259 (259) Show / Hide 
Range on Protein: 33-178
Range on HMM: 107-259/259
Sequence Identity: 30% (49 aa)

IISAVAYIHSKSYMHLDISPSNILQCSHPIVGNIYKLADFGTTLPVDNFKE---DFEGAGPYVSPETLQYPNTEYPVSSPTDIFSLGVVLLEMVTRKYAP
|. .|...|..  .| |. | |.|  |  . |   ||||||  . |.. ..    | |   |.||| |.      | . | ||.  ||.|  ..   | |
ILESVNHCHQNGIVHRDLKPENLLLASK-CKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLR----KDPYGKPVDIWACGVILYILLVG-YPP

----RAFPAYGDLRSGKYDFSK------IPKEFSFISQMLAPNPMERPTAEQLLKLDGV
         |  .. | ||.         |   . | |||. ||  | ||.. ||   .
FWDEDQHRLYQQIKAGAYDYPSPEWDTVTPEAKNLINQMLTINPKKRITADEALKHPWI
Kinase 90756.m00167.AA CAMK 28-119 21 1.1e-12 36.47 In-house 183-324 (425) Show / Hide 
Range on Protein: 28-119
Range on HMM: 183-324/425
Sequence Identity: 21% (30 aa)

KVFAHIISAVAYIHSKSYMHLDISPSNILQCSHPIVG-------------NIYKLADFGTT--LPV------------------------DNFKEDFEGA
..|  |.|||.|.||.  .|.|. | ||| ...                 |  |..|||    ..                         .   ..| | 
RYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGT

GPYVS-PETLQYPNT----------EYPVSSPTDIFSLGVVL
 .|.. || |..  .          . ... ..|. |.||.|
PEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase 90756.m00167.AA PEK 110-178 29 1.3e-12 39.56 In-house 575-655 (655) Show / Hide 
Range on Protein: 110-178
Range on HMM: 575-655/655
Sequence Identity: 29% (24 aa)

TDIFSLGVVLLEMVTR--KYA-PRAFPAYGDLRS------GKYD----FSKIPKEFSFISQMLAPNPMERPTAEQLLKLDGV
.|..|||....||  .   .  .|. .   |||.      |...     .| ||. .||..|| ..| .||.|.|.|. . .
VDMYSLGIIFFEMWYPFFTTMMERVKT-LTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase 90756.m00167.AA PEK 137-178 44 4.5e-11 31.98 In-house 714-758 (758) Show / Hide 
Range on Protein: 137-178
Range on HMM: 714-758/758
Sequence Identity: 44% (20 aa)

DLRSGKY--DFSK-IPKEFSFISQMLAPNPMERPTAEQLLKLDGV
|||.|..  .| .  |.|  ||.||. .||.||||| |... | .
DLRNGQWPKWFTQKYPQEYEFIQQMMSMNPDERPTADQISMHDFF
Kinase 90756.m00167.AA Ciliate-E2-Unclassified 3-127 24 6.4e-11 34.14 In-house 97-268 (352) Show / Hide 
Range on Protein: 3-127
Range on HMM: 97-268/352
Sequence Identity: 24% (43 aa)

YLQMELAEFGSIRPRYLK--------------------LPTQEIW-----KVFAHIISAVAYIHSKS-YMHLDISPSNILQCSHPIVGN----IYKLADF
|. ||..| |. .    |                    .. |..      . ||.|...  |.|.|    | || |.|||     .  |      |..||
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL-----FDNNGKNYYIKIIDF

GTTL---PVDNFKEDFE----------------GAGPYV----SPETLQYPNTEYPVSSPTDIFSLGVVLLEMVTRKY
|        .|.. ..                 |   |     .|| ||  | . . .   ||.||||.| ||.. .|
GISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY
Kinase 90756.m00167.AA S_TKc 3-189 18 2.1e-10 -24.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 3-189
Range on HMM: 1-231/231
Sequence Identity: 18% (48 aa)

Y--------------------------------------------------------------LQMELAEF--GSIRPRYLK---------LPTQEIWKV
|                                                              . ||...   |. . .  |         .|  .....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

FAHIISAVAYIHSKSYMHLDISPSNILQCSHPIVGNIYKLADFGTTLPVDNFKEDFEGAGPYVSPETLQYPNTEYPVSS-PTDIFSLGVVLLEMVTRKYA
.. |..|..|.||.  .| |. |.||| ..        |..|||    .      | |   |..|| |       . .  . |. |.|..| ||..  | 
MYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL-------GYGKCKCDWWSCGCILYEMLC-GYP

PRAFPAYGDLRSGKYDFSKIPKEFS-FISQMLAPNPMERPTAEQLLK--LDGVQRELNLLHPYV
|     .  ..  .      ..|.  ||...|  .| .|||| ..|.  .|        .||..
PFP-QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWD------IKCHPWF
Kinase 90756.m00167.AA NEK 25-73 29 1.1e-08 27.12 In-house 115-168 (286) Show / Hide 
Range on Protein: 25-73
Range on HMM: 115-168/286
Sequence Identity: 29% (16 aa)

EIWKVFAHIISAVAYIHSK-----SYMHLDISPSNILQCSHPIVGNIYKLADFG
.||..|.....|. |.|..       .| || |.||   .  .  .. |. |||
QIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFG
Kinase 90756.m00167.AA PEK 19-56 34 2.4e-08 24.38 In-house 422-459 (655) Show / Hide 
Range on Protein: 19-56
Range on HMM: 422-459/655
Sequence Identity: 34% (13 aa)

LKLPTQEIWKVFAHIISAVAYIHSKSYMHLDISPSNIL
........|. |. |.....||||.  .| |. ||||.
MFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIF
Kinase 90756.m00167.AA NEK 153-178 38 8e-06 16.92 In-house 261-286 (286) Show / Hide 
Range on Protein: 153-178
Range on HMM: 261-286/286
Sequence Identity: 38% (10 aa)

SFISQMLAPNPMERPTAEQLLKLDGV
..||||| ..| .||...|.|..  .
NLISQMLQKDPEQRPSCNQILEMPFI
Kinase 90756.m00167.AA CAMK 153-174 40 2.3e-05 12.48 In-house 400-421 (425) Show / Hide 
Range on Protein: 153-174
Range on HMM: 400-421/425
Sequence Identity: 40% (9 aa)

SFISQMLAPNPMERPTAEQLLK
..|..|| ..| .|.|.|| |.
DLIRKMLQVDPEKRMTIEQCLN
Kinase 90756.m00167.AA PEK 33-55 56 0.001521 6.34 In-house 451-473 (758) Show / Hide 
Range on Protein: 33-55
Range on HMM: 451-473/758
Sequence Identity: 56% (13 aa)

IISAVAYIHSKSYMHLDISPSNI
|...| |||||  .| |  ||||
ICEGVNYIHSKGMIHRDLKPSNI
Kinase 90756.m00167.AA Ciliate-E2-Unclassified 154-178 37 0.010268 5.27 In-house 324-352 (352) Show / Hide 
Range on Protein: 154-178
Range on HMM: 324-352/352
Sequence Identity: 37% (11 aa)

FIS----QMLAPNPMERPTAEQLLKLDGV
||.    .||  || .|.|.||.|.    
FINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 90756.m00167.AA PEK 110-122 46 0.078298 0.51 In-house 685-697 (758) Show / Hide 
Range on Protein: 110-122
Range on HMM: 685-697/758
Sequence Identity: 46% (6 aa)

TDIFSLGVVLLEM
.||.||| .. |.
VDIYSLGLIFFEL