Gene 83472.m00442 (T.vaginalis)

83472.m00442

Species: T.vaginalis
Alias: 83472.m00442, TvagK0029
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag4

Sequence

Name Sequence Type Origin Length Description Download
83472.m00442.AA Protein None 496 None Fasta, JSON
83472.m00442.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 83472.m00442.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83472.m00442.AA AMPK 11-262 47 7.79999999999e-133 396.66 In-house 1-254 (254) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-254/254
Sequence Identity: 47% (121 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIKKDSFKDNPQLQPKIQREIALMRLFDHPHILKLLDIL-ESPRHLYIGLEYASHGELFTYVVENKQISE
|..  ..| |.  |.|...|. |.  |||||. |.  ||  . . .||||| ...|| |||| .| ... |.|. ... .||.| |||| |.| .. ..|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQ-DMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQE

QAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYNIKIADFGFARFTKKNVA-ETSCGSPHYVAPEVIGGEVYDGRCADVWSCGVILYALLTGNLP
. | ||| ||| |.||.| ..| ||||||||.|||...||||.|||     |..    |.|||| | |||.| |  | |.. |.|||||||||.| | ||
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

FDDPSIRNLLAKVRRGVFTMPD-VSDPLKDLISKMLTKDPKQRITIRQIKEHPAF
|||.....| .|.. |... |. .|.  ||||..||..|| .|||| .|..|| |
FDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 83472.m00442.AA CAMKL 11-262 41 1.6e-131 422.09 In-house 1-297 (297) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-297/297
Sequence Identity: 41% (123 aa)

YMLVRNLGSGSTSKIKLAIH-QETKMPVAIKIIKKDSFKDNPQLQPK-----------IQREIALMRLFD---HPHILKLLDILESPRH------LYIGL
| ... || || .| |||.| . |.  ||||||.|.  ...|. . .           |.|||..|....   ||.| ||....| |.|      .|. .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASHGE--LFTYVVENKQ----ISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKY--NIKIADFGFARF-TK-----KNVAETSCGSPHYV
||.| ||  || |.|...     ..|  | |.||||. ...|.||.||.|||.||||||||..   ||||.||||. . ..      .  .|.||||.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APEVIGG--EVYDGRCADVWSCGVILYALLTGNLPFDDP--------SIRNLLAKVRRGVFTMP---DVSDPLKDLISKMLTKDPKQRITIRQIKEHPAF
|||.. |  . |||. .|.|||||||||...|.|||||.         | .|. |...| . .|   .|| ...|||.|||...|..|.|| ||..|| .
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 83472.m00442.AA CAMK 16-262 28 9.1e-123 397.64 In-house 1-425 (425) Show / Hide 
Range on Protein: 16-262
Range on HMM: 1-425/425
Sequence Identity: 28% (122 aa)

NLGSGSTSKIKLAIHQETK------------MPVAIKIIKKDSFKD------------------------NPQLQPKIQREIALMRL-------FDHPHI
 ||.|| .| ||.|| .|.              ||||||.|.  ||                        .|. . ...|||..|..        |||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKLLDILESPRH-------------------LYIGL---EYASHGEL----FTYVVENKQ---------------ISEQAAMRFFRQIIYGLEYLHSLGI
.||... |.|..                   .|. .   ||.| |||    | |.||...               ..|. | |.||||. ...|.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

CHRDLKPENILLDDK-----------------YNIKIADFGFARFTKKNV-------------------------AETSCGSPHYVA-PEVIGG------
.|||||||||||||.                 .||||.|||||.. ...                           .|.||.|.|.| |||. |      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EVYDGRCADVWSCGVILYALLTGNLPFDDP-------------SIRNLLAKVRRGVFTMPD-------------------------VSDPLKD
       . |.|. .|.||||||||..|.| .||...             ....|. |...| ...|.                         ||.  ||
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISKMLTKDPKQRITIRQIKEHPAF
||.|||..||..|.|| |...|| .
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 83472.m00442.AA BRSK 11-262 53 6.30000000001e-119 401.41 In-house 1-254 (254) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-254/254
Sequence Identity: 53% (135 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIKKDSFKDNPQLQPKIQREIALMRLFDHPHILKLLDILESPRHLYIGLEYASHGELFTYVVENKQISEQ
| | . || | | ..|| .|  |   |||||| |    . . .  |. ||||.|.| ||||..|. |. |  . ||  ||. | |||| | |.      .
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

AAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYNIKIADFGFARFTKKN-VAETSCGSPHYVAPEVIGGEVYDGRCADVWSCGVILYALLTGNLPF
 | .|||||| .|.. ||  |||||||||| |||.| |||||||| |    |    .||||||||  |||| || |||| ||||||||||||||.| |||
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVKDMMLHTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF

DDPSIRNLLAKVRRGVFTMPD-VSDPLKDLISKMLTKDPKQRITIRQIKEHPAF
||  .|.|| ||.|||| ||  .     ||  .|.. ||..||.. .|..|| .
DDDNLRQLLEKVKRGVFHMPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY
Kinase 83472.m00442.AA MARK 11-262 40 1.1e-109 359.65 In-house 1-262 (262) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-262/262
Sequence Identity: 40% (106 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIKKDSFKDNPQLQPKIQREIALMRLFDHPHILKLLDILE--SPRH-LYIGLEYASHGELFTYVVEN--K
|.... .| || .| |||.|. |.  |||||..| .  |. .... ..|||..|.. |||.| ||... |   ..| .|. .|||| |||. |...    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKN-VMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

QISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKY--NIKIADFGFARFTKKNV-AETSCGSPHYVAPEVIGGEVYDGRCADVWSCGVILYAL
 ..|  | |.||||.....|.|| .|.|||.||||||.|..   ||||.||||..  . .   .| ||.| | |||.. .. |||. .|.||.||.||..
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM

LTGNLPFDDPS--IRNLLAKVRRGVFT-MPDVSDPLKDLISKMLTKDPKQRITIRQIKEHPAF
..|..|||. .  . .|  |..||...  . ||. ...||...|| .|..|.|| .| .|| .
VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 83472.m00442.AA S_TKc 11-262 37 4e-106 359.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-231/231
Sequence Identity: 37% (101 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIKKDSFKDNPQLQPKIQREIALMRLFDHPHILKLLDILESPRHLYIGLEYASH--GELFTYVVENKQ--
| ..| .|.|. .| ....| .|.  |||||||            .|.|||....  .||.| ||.|. ..  |||. .||...  |.||.| ....   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----ISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYNIKIADFGFARFTKKNVAETSCGSPHYVAPEVIGGEVYDGRCADVWSCGVILYAL
    ..|  | ....||. .|||.||.||.||||||||||||.  .|||.|||.||.       | ||.|.|.||||.    |... .|.||||.||| .
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LTGNLPFDDPSIRNLLAKVRRGVFTMPDVSDPLKDLISKMLTKDPKQRITIRQIKE-------HPAF
|.|  ||.   .  .. |..         |...||.|.|.|.|||..|.|. .. .       || |
LCGYPPFP--QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83472.m00442.AA CAMK1 11-263 38 3.7e-102 297.75 In-house 1-276 (276) Show / Hide 
Range on Protein: 11-263
Range on HMM: 1-276/276
Sequence Identity: 38% (107 aa)

YMLVRNLGSGSTSKIKLAIHQET---KMPVAIKIIK-KDSFKD---NPQLQPKIQREIALMRLF---DHPHILKLLDILESPRHLYIGLEYASHGELFTY
| .   .|.|. |. .|..| ||   . ..|||.|. |.. |      . | ....||. |. .   |||.| |. .. ||..|.|. .|. . ||||  
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQ-K-QEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDR

VVENKQISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYN---IK--IADFGFARFTKKN--VAETSCGSPHYVAPEVIGG---EVYDGRCA
.||... .|. | .  .||.  .||.||.||.||||||||.|. ||..   ||  ||||| ..... .  . .| ||.| ||||||. .   . ||  | 
IVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKAC-

DVWSCGVILYALLTGNLPFDDPS-IRNLLAKVRRGVFTMP-----DVSDP-LKDLISKMLTKDPKQRITIRQIKEHPAFI
|.||.|||.| ||.|  || | . . .|..|. .. ...|     ..||   ||.|..||..|||.|.|. |. .|| .|
DMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHP-WI
Kinase 83472.m00442.AA GIN4 57-262 53 6.5e-98 313.35 In-house 81-293 (293) Show / Hide 
Range on Protein: 57-262
Range on HMM: 81-293/293
Sequence Identity: 53% (114 aa)

IQREIALMRLFDHPHILKLLDILESPRHLYIGLEYASHGELFTYVVENKQISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYN-IKIADFG
| ||| .|.| .|| ...| |. |    ||. ||||  |||| |.|.  .. |. |...||||| |. | |...||||||||||.||| ||| |||||||
IEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVDHGPLPEREAIHYFRQIIIGVSYCHAFNICHRDLKPENLLLDHKYNRIKIADFG

FARF-TKKNVAETSCGSPHYVAPEVIGGEVYDGRCADVWSCGVILYALLTGNLPFDDP--SIRNLLAKVRRGVFTMPDV---SDPLKDLISKMLTKDPKQ
 |   |. .. ||||||||| |||.. |  |.|  .|||||||||.||||| ||||.    ||.|| || .| . ||.    |   .|||.|.|. ||..
MAALETDNKLLETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGNIRKLLLKVQKGKYEMPSDDEISREAQDLIRKILVVDPEK

RITIRQIKEHPAF
||..|.| .||  
RIKTRDILKHPLI
Kinase 83472.m00442.AA Pkinase 11-262 35 2.8e-95 327.63 Pfam 1-293 (293) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-293/293
Sequence Identity: 35% (106 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIKKDSFKDNPQ-----LQPKIQREIALMRLFDHPHILKLLDILESPRHLYIGLEYASHG----ELFTYV
| ..| .|||| .. ....|. |   ||.|||||.. |.. .     |     .||..|. ..||.|..|.|. |...|.|. .||. .|    .||.|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

V--ENKQI--SEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYNI----KIADFGFARF--TKKNVAETSCGSPHYVAPEVIGGEVYDGRCAD
   ... .  ||. . ....||. ||||.|| ||.||||||||||.|....|    ||.|||.|..  . .|.. | ||.|.|.||||| |  |.|. .|
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVD

VWSCGVILYALLTGNLPFDDP----SIRNLLAKVRRGVFTMPDVS-------------------------DPLKDLISKMLTKDPKQRITIRQIKEHPAF
.||||.||| .|.|..||..     . .. .....|   . .. .                         ...||.|...|.||||.|.|..||..|| |
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83472.m00442.AA QIK 11-262 41 1.2e-93 317.48 In-house 1-272 (272) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-272/272
Sequence Identity: 41% (115 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIKKDSFKDNPQLQPKIQREIALMRLFDHPHILKLLDILESPRHLYIGLEYASHGELFTYVVENKQ----
| . | .| |    .||| |  ||  |||||| |    |   || |. ||...| . .|||| ||....|. . .||  ||.| ||.| |.... .    
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQL-DEENLQ-KCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVK

----------------ISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYNIKIADFGFARFTKKNV-AETSCGSPHYVAPEVIGGEVYDGRC
                ..|..| | | ||. . .|.|...| ||||| ||||||   |||||||||  . |.    .| |||| | |||.  |. |||  
MVNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

ADVWSCGVILYALLTGNLPFDDPSIRNLLAKVRRGVFTMP-DVSDPLKDLISKMLTKDPKQRITIRQIKEHPAF
.|.|| ||.||.| .| |||| ... || ..|  | | .|  .|  . .|| .||. ||..|.|| ||..|.  
VDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 83472.m00442.AA Ciliate-E2-Unclassified 11-262 26 8.5e-85 288.02 In-house 1-352 (352) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-352/352
Sequence Identity: 26% (94 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPV-----AIKIIKKDSFKDNPQLQPKIQREIALMRL------------------FDHPHILKLLDILESPRHLYI
| ... .|.|. .|.....| ..|  .     ..||..... . . .   ... .......                  ..||.|.|.... ..  ..||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

GLEYASHGELFTYVVENKQ-----------------ISEQAAM-----RFFRQIIYGLEYLHSLG-ICHRDLKPENILLDDKY---NIKIADFGFAR---
 .||. .|.|. |  ..|.                 ..||.|      ..|.||. ||||||. . |.|||.||||||.|..    .|||.|||...   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------------FTKKNVAETSCGSPHYV----APEVIGGEVYDGR---CADVWSCGVILYALLTGNLPFDDPSIRN----------------LLAKV
              ..|.. . | ||.| |     ||||..|. ||..   ..|.||.|||||..|.|..||.|..                   |. . 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

RRG---VFTMP------DVSDPLKDLIS----KMLTKDPKQRITIRQIKEHPAF
  .   .. .|      ..|.  ||.|.    ||| |.|..|||. ||..|| |
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 83472.m00442.AA ULK 11-262 29 5.8e-84 285.25 In-house 1-324 (324) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-324/324
Sequence Identity: 29% (97 aa)

YMLVRNLGSGSTS-KIKLAIHQET---KMPVAIKIIKKDSFKDNPQLQP------KIQREIALMRLFD---HPH--ILKLLDILESP--RHLYIGLEYAS
| | . ||.||   |   .....|   .  ||.|.| |.........|.      ....|| .|. ..   ||.  | ||.|..|..   ..|| .||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

HGELFTYVVENKQ---------ISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYN------------IKIADFGFARFTKKN-VAETSC--
.| |..|  .||          .||| |  ||.||. |. .||. .| |||.||.|||. ..              .||||||||..  .|  ... |  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GSPHYVAPEVIG----GEVYDGRCADVWSCGVILYALLTGNLP----FDDPSIR--NLLAK-------VRRGVFTMPD------VSDPLKDL
        |.| | ||...     .. |.   .|.|| |.|.| .|.|  |    | |  ..  .|. .       ..   .  |.      .|. .|||
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDL

ISKMLTKDPKQRITIRQIKEHPAF
|..||..|.|.||.. .| .|| |
IRRMLQYDEKDRISWEEIFNHPWF
Kinase 83472.m00442.AA TyrKc 11-262 24 1.8e-19 71.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 11-262
Range on HMM: 1-280/280
Sequence Identity: 24% (71 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIKKDSFKDNPQLQPKIQREIALMRLF--DHPHILKLLDILESP-------RHLYIGLEYASHGELFTYV
  | . ||.|   .. ...     ..||.| .|.|.       .  . ||. .|. .  .||.|..|. .  ..         |.| .||..|| |  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

VENKQ-ISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYNIKIADFGFARFTKKN------VAETSC----GSP-----HYVAPEVIGGEVY
 ...  .. .    |  ||  | ||||| .. ||||   |.|..... .||.||| .|. .            .     |.         |||.|   ..
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DGRCADVWSCGVILYALLT-GNLPFDD-----PSIRNLLAKVRRG--VFTMPD--------VSDPLKDLISKMLTKDPKQRITIRQIKEHPAF
     |||| || .. ..| |  |  .      | . ....|..|     .|.         .| . .....    ||..| | ..|  |  |
TTKS-DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 83472.m00442.AA Pkinase_Tyr 11-158 27 3.2e-19 65.74 Pfam 1-159 (270) Show / Hide 
Range on Protein: 11-158
Range on HMM: 1-159/270
Sequence Identity: 27% (45 aa)

YMLVRNLGSGSTSKIKLAIHQ----ETKMPVAIKIIKKDSFKDNPQL--QPKIQREIALMRLF-DHPHILKLLDILE-SPRH--LYIGLEYASHGELFTY
  . . ||.|.  ......      .||.|||.|..|    .  ..   . .  ||...|. . .||.|..|. .     ..  .|| .||. || | .|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

VVE----NKQISEQAAMRFFRQIIYGLEYLHSLGICHRDLKPENILLDDKYNIKIADFGFAR
  .    ..... .    . .||  |.|||.| .. ||||   |.|....  .||.||| ||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 83472.m00442.AA GIN4 11-47 42 5.2e-07 17.99 In-house 1-38 (293) Show / Hide 
Range on Protein: 11-47
Range on HMM: 1-38/293
Sequence Identity: 42% (16 aa)

YMLVRNLGSGSTSKIKLAIHQETKMPVAIKIIK-KDSF
. | . || ||| |..|| ..||    |.|.|  |  |
WKLGETLGFGSTGKVQLAKNMETGQRAAVKVISKKKIF