Gene 90655.m00128 (T.vaginalis)

90655.m00128

Species: T.vaginalis
Alias: TvagK0409, 90655.m00128
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
90655.m00128.AA Protein None 459 None Fasta, JSON
90655.m00128.kin_dom Protein Kinase Domain None 285 None Fasta, JSON

Protein domain

Protein domains of 90655.m00128.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90655.m00128.AA AGC 101-385 26 1.9e-130 339.17 In-house 1-395 (395) Show / Hide 
Range on Protein: 101-385
Range on HMM: 1-395/395
Sequence Identity: 26% (113 aa)

YNFITLIGRGGFADVWLVTDK------KTEQPYAMKIIRKSD-VIVSD--QITATRNE------------RDILAIAH----------NPWIVQ-LQCSF
..|...||.|.|  |.|| .|       |.. ||||...|.. ..  .  ..  | .|            |.||. ..          .|.||. | .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDEH--LYLILEFVQ---------GG-DLMNALI---KVGTFVPKVARFFTAE-------IVLAVNSVHK-LGFIHSD-LKPDNILIASTGHIKLTDFG
||..|  ||...|...         || .|.  |    | |.|  ..|||..||       ||||. . |. .|.|| | |||.|||. . |||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

IASA-------------------------------YGKSDADYDELLRETQDLMLDNDNPIVPSQTQRHH-------------HRNSIIG--TVDYIAPE
 .                                                        . . |.. ||.                ... |  | .|.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTN----------------------K-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPE

VLRGDPPNVKNDWWS--LGVILYEMLYGFTPFSSDS----------KNETVFRII------NWKKSL------RIPASKPVPVSALDLLRHLLC-DIENR
.|     .   ||||  ||...||||.| .||..|.          ..|.  .|.      |||  .       .|. . . . | ||...||| | |.|
IL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR

YG----------YEEIIHHAFF
 |          .|||  | .|
LGCGGNDFGDKGAEEIKNHPWF
Kinase 90655.m00128.AA NDR 101-385 36 1e-122 380.54 In-house 1-350 (350) Show / Hide 
Range on Protein: 101-385
Range on HMM: 1-350/350
Sequence Identity: 36% (128 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAH--NPWIVQLQCSFQDDEHLYLILEFVQGGDLMN---ALIKVGT
. .|..||.|.|  ||||  |.|.. |||||.|||...  .|..  |.||||.|.|.  |||.| | .||||. .|||. |.. |||.|     |.| ..
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FVPKVARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFGIASA------------------------------YGKSDADYDELLRETQD
|   .|||  ||.|.|..||||.|.|| |.||||.|| . ||||||||| .                                |....    .  .....
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

LMLDNDNP-----------------IVPSQTQRH-HHRNSIIGTVDYIAPEVLRG-DPPNVKNDWWSLGVILYEMLYGFTPFSSDSKNETVFRIINWKKS
 . .|..                    .|  |.  .  .|..|| ||.||||. .    |   ||||||.|.|||| |..|| ||. .||  .|.|||. 
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----RIPASKPVPVSALDLLRHLLC-DIENRYG-----YEEIIHHAFF
.      .|.  .. . | ||.| |.| | ..| |      .||  | ||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase 90655.m00128.AA S_TKc 101-385 31 6.8e-90 305.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 101-385
Range on HMM: 1-231/231
Sequence Identity: 31% (94 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAHNPWIVQLQCSFQDDEHLYLILEFVQG--GDLMNALIKVGT---
| .. .||.|.|. |.....||| . .|.|||.            .|.|..||   | |.||.|  .||| .|||...|.. |  |||.  . | |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FVPKVARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFGIASAYGKSDADYDELLRETQDLMLDNDNPIVPSQTQRHHHRNSIIGTV
   | . .|||....|..|..  |..|.|| ||||.|||. .  |||..|||.|  .                                    ....|| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------TTFCGTP

DYIAPEVLRGDPPNV-KNDWWSLGVILYEMLYGFTPFSSDSKNETVFRIINWKKSLRIPASKPVPVSALDLLRHLLC-DIENRYGYEEIIH-------HA
.|.|||||   . .  | ||||.|.||||||.| .||.     ...|..|              . .|.|..|..|. | |.|..  |. .       | 
WYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

FF
.|
WF
Kinase 90655.m00128.AA MAST 101-385 30 2.6e-86 263.62 In-house 1-337 (337) Show / Hide 
Range on Protein: 101-385
Range on HMM: 1-337/337
Sequence Identity: 30% (104 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAHNPWIVQLQCSFQD--DEHLYLILEFVQGGDLMNALIKVG-TFV
..|| .|..|..  |.||  ||| . .|||.|...| |   |.   . ||.||... ||..| . .|||   ...|....|...|||    |  .| .. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

PKVARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFGIASA----------YG---------------KSDADYDELL------------
   |.. .||.||..   |. | .| ||||||.|| |.||||||||| .             |               ... .| ..             
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

---RETQDLMLDNDNPIVPSQTQRHHHRNSIIGTVDYIAPEVLRGDP-PNVKNDWWSLGVILYEMLYGFTPFSSDSKNE-TVFRIINWKKSLRIPAS---
    . . .  .  |.. |   ..    ....|| |||||||. | .  .   ||||.|.|.|| | | .||  |. .| .   ||| .. .  |     
QIQQQQEQPQCQQQNEMRPHNIHQ---NKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDP

---KPVPVSALDLLRHLL-CDIENRYGYE---EIIHHAFF
    ...  | || . ||  .   | |     ||  |.||
NDDDCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase 90655.m00128.AA DMPK 101-244 40 4.4e-85 209.96 In-house 1-145 (270) Show / Hide 
Range on Protein: 101-244
Range on HMM: 1-145/270
Sequence Identity: 40% (58 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAHNPWIVQLQCSFQDDEHLYLILEFVQGGDLMNALIKVG-TFVPK
. ....|||| |. | .|  |.|.. ||||.. | . .   .    . ||||....  .||.||.. |||...||.. |.  |||| . . . .  . ..
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

VARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFG
 ||| .||.|||..|.|..|..| | ||||.|. ..||||| |||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFG
Kinase 90655.m00128.AA MAST 101-385 31 1.4e-81 262.68 In-house 1-334 (334) Show / Hide 
Range on Protein: 101-385
Range on HMM: 1-334/334
Sequence Identity: 31% (108 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAHNPWIVQLQCSFQDDEHLYLILEFVQGGDLMNALIKVGTFVPKV
..|| .|..|..  |.||  ||| . .|||.|.||| |   ..   . ||.|||.. ||..| . .||| ...|....|...|||.   |  .|.|    
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFGIASA----------YG---------------KSDADYDELL---------------
|.. .||.||..   |. | .| ||||||.|| |.||||||||| .             |               |.. || ..                
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

RETQDLMLDNDNPIVPSQTQRHHHRNSIIGTVDYIAPEVLRGDP-PNVKNDWWSLGVILYEMLYGFTPFSSDSKNETVFRIINWKKS-LRIPAS------
 . . .  .  | . | . ..    ....|| |||||||. | .  .   ||||.|.|.|| | | .||  |. .|.   |.| .     .|        
QQQEQPQCQQQN-MRPHNIHQ---NKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDD

KPVPVSALDLLRHLL-CDIENRYGYE----EIIHHAFF
.  .. | || . || .| . | |      |.  | ||
EAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 90655.m00128.AA RSK 104-385 33 2.8e-76 259.75 In-house 1-278 (278) Show / Hide 
Range on Protein: 104-385
Range on HMM: 1-278/278
Sequence Identity: 33% (104 aa)

ITLIGRGGFADVWLVTDK---KTEQPYAMKIIRKSDVIVSDQ-ITATRNERDILAIAH-NPWIVQLQCSFQDDEHLYLILEFVQGGDLMNALIKVGT---
. . |.||.  | |.  .   .|.| ||||...|. .....  .  |. ||.||.     | ||.|  .||....||||.|.. ||.|   | | ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FVPKVARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIAS---TGHIKLTDFGIASAYGKSDADYDELLRETQDLMLDNDNPIVPSQTQRHHHRNSIIGTV
|  . |.|  |||||||   |..|.|| ||||.||| ..    ||||||||| .                            .....|. .   . ..|.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------RCDHNQWTM---TFCYTI

DYIAPEVLR-GDPPNV----KNDWWSLGVILYEMLYGFTPFSS---DSKNETVFRIINWKKSLRIPASKPVPVSALDLLRHLLC-DIENRYG-----YEE
.|.|||.|. .. ...      |||||||..|||| |..|| .   ....|.  || . | ||..|. . .   | ||.|..|. | ..|.|      ||
EYMAPEMLKRAN-QQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEE

IIHHAFF
|  |..|
IKQHPWF
Kinase 90655.m00128.AA AktR 101-385 31 5.3e-74 252.16 In-house 1-268 (268) Show / Hide 
Range on Protein: 101-385
Range on HMM: 1-268/268
Sequence Identity: 31% (93 aa)

YNFITLIGRGGFADVWLVTDK-KTEQPYAMKIIRKSDVIVSDQITATRNERDILA-IAHNPWIVQLQCSFQDDEHLYLILEFVQGGDLMNALIKVGTFVP
. .. ..|.|.|..| ||..| .. . ||||.|.|.. |   |. .|..||.|.. .. .| ||.|  .||..|.|..|.|...||.| . | | ..|  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

KVARFFTAEIVLAVNSVHKL-GFIHSDLKPDNILIASTGHIKLTDFGIASAYGKSDADYDELLRETQDLMLDNDNPIVPSQTQRHH--HRNSIIGTVDYI
..|||. |.|.||.   |.    |  ||||.|||. . ||.|.|||| .                               | ..|   . .|. ||. |.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-----------------------------LQFMMHYDEKAYSFCGTPEYM

APEVLRG-DPPNVKNDWWSLGVILYEMLYGFTPFSSDSKNETVFRIINWKKSLRIPASKPVPVSALDLLR-HLLCDIEN------RYGYEEIIHHAFF
|||...  .. |   |||..|. .|||..| .|| ....|. ...|..    ...| ....   . ||.   |||.  |      . | |||  | .|
APEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 90655.m00128.AA Pkinase 101-385 27 1.8e-65 228.62 Pfam 1-293 (293) Show / Hide 
Range on Protein: 101-385
Range on HMM: 1-293/293
Sequence Identity: 27% (89 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATR-NERDILAIAHNPWIVQLQCSFQDDEHLYLILEFVQGG----DLMNALI--KV
| ..  ||.|.|. |.. ..|.|.. .|.|||.|..   . ..|..| .|  |..  . | ||.| ..|.|. |.|...|...||    ||.  .   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GTF--VPKVARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHI----KLTDFGIASAYGKSDADYDELLRETQDLMLDNDNPIVPSQTQRHHHRNS
|.|   .....|.  .|. ...  |. |.|| ||||.|||| ..|||    |..|||.|  .                             . . .  ..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------------------Y-NNS-MTT

IIGTVDYIAPEVLR-GDPPNVKNDWWSLGVILYEMLYGFTPFSSD------SKNETVFRIINWKKSLRIPASKPVP-----------------VSALDLL
. || .|.||||.| | .   | |.||.|.|||||| | .||...      .... ..||   . .  .| . ...                  ...|..
FCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

RHLLC-DIENRYGYEEIIHHAFF
. .|| | . |.. |.| .| .|
KWCLCKDPKKRPTAEQILQHPWF
Kinase 90655.m00128.AA CRIK 101-248 43 3.9e-57 180.52 In-house 1-149 (272) Show / Hide 
Range on Protein: 101-248
Range on HMM: 1-149/272
Sequence Identity: 43% (65 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAHNPWIVQLQCSFQDDEHLYLILEFVQGGDLMNALIKVG-TFVPK
.   .|||.| |..| .|  | |   ||||...|. |  ..|.     ||||....  ||. |||  |||...|||. |.  ||||   .   .  |   
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

VARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFGIASA
 |||. || ..|| |.|. |..| | ||.||||  |||||| ||| | .
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSAAK
Kinase 90655.m00128.AA ROCK 101-244 45 1.6e-52 177.08 In-house 1-143 (263) Show / Hide 
Range on Protein: 101-244
Range on HMM: 1-143/263
Sequence Identity: 45% (66 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAHNPWIVQLQCSFQDDEHLYLILEFVQGGDLMNALIKVGTFVPKV
...| .|||| | .| || .|.... ||||.. | ..|          ||||.| |  .|||||.. |||| .||...... ||||.| |.       | 
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVN-LMSNYDVPEKW

ARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFG
|||.|.|.|||....| .|||| | ||||.|. . ||.|| |||
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFG
Kinase 90655.m00128.AA DMPK 289-385 44 8e-50 120.78 In-house 162-270 (270) Show / Hide 
Range on Protein: 289-385
Range on HMM: 162-270/270
Sequence Identity: 44% (49 aa)

IGTVDYIAPEVLRGDPPN------VKNDWWSLGVILYEMLYGFTPFSSDSKNETVFRIINW-KKSLRIPASKP--VPVSALDLLRHLLCDIENRYG---Y
.|| |||.||||.    .      .  ||||.||..|||||| |||. ||  ||   | |  | .|  |.. .  |...| ||.. |||| |.| |   |
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

EEIIHHAFF
|..  | ||
EDFKCHPFF
Kinase 90655.m00128.AA GEK 101-244 42 9.4e-49 161.58 In-house 1-145 (269) Show / Hide 
Range on Protein: 101-244
Range on HMM: 1-145/269
Sequence Identity: 42% (62 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIAHNPWIVQLQCSFQDDEHLYLILEFVQGGDLMNALIKVGTFVPK-
.. . .|||| |..|  |  |.|.| |||||. | ...    ..  | |||.|    . || .|   |||...|||....  ||||.  | | .  .|. 
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

VARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFG
.|||. ||.|.|..|||.|...| |.||||.|.   |||.| |||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFG
Kinase 90655.m00128.AA CRIK 289-385 37 1e-31 98.1 In-house 162-272 (272) Show / Hide 
Range on Protein: 289-385
Range on HMM: 162-272/272
Sequence Identity: 37% (42 aa)

IGTVDYIAPEVLR---GD-----PPNVKNDWWSLGVILYEMLYGFTPFSSDSKNETVFRIIN------WKKSLRIPASKPVPVSALDLLRHLLCDIENRY
.|| ||.|||||    |.        |  ||||.|.| ||| .| |||. |.  .|   |.|       .. |  |.. .| . ..||.. |||.   | 
VGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDPKVSPNYRDLIQSLLCNQSKRL

GYEEIIHHAFF
.|| .  | ||
KYEQLCCHPFF
Kinase 90655.m00128.AA GEK 289-385 41 5.2e-26 83.94 In-house 162-269 (269) Show / Hide 
Range on Protein: 289-385
Range on HMM: 162-269/269
Sequence Identity: 41% (45 aa)

IGTVDYIAPEVLR----GDPPNVKN-DWWSLGVILYEMLYGFTPFSSDSKNETVFRIINWKKSLRIPASKP---VPVSALDLLRHLLCDIENRY---GYE
.|| |||.||.|.    |     .. |||||||..|||||| ||| ..|  ||  .|.|.|  . .|. .    |. .| ||.|.|.|  |.|    | .
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

EIIHHAFF
.  .|.||
DFKKHPFF
Kinase 90655.m00128.AA ROCK 289-385 41 6.2e-24 78.14 In-house 160-263 (263) Show / Hide 
Range on Protein: 289-385
Range on HMM: 160-263/263
Sequence Identity: 41% (43 aa)

IGTVDYIAPEVLRGDPPNVK----NDWWSLGVILYEMLYGFTPFSSDSKNETVFRIINWKKSLRIPASKPVPVSALDLLRHLLCDIENR---YGYEEIIH
.|| |||.||||.    . .     |||| || .|||| | |||  ||   |  .|.. | ||. |    .   | ||..  | | |.|   .| ..| .
VGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIKQ

HAFF
| ||
HKFF
Kinase 90655.m00128.AA TyrKc 101-384 20 4.2e-09 -75.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 101-384
Range on HMM: 1-280/280
Sequence Identity: 20% (65 aa)

YNFITLIGRGGFADVWLVTDKKTEQPYAMKIIRKSDVIVSDQITATRNERDILAIA--HNPWIVQLQCSFQDD-------EHLYLILEFVQGGDLMNALI
  ..  .|.| |  |.. | |   .. | | ....       . . ..|  |.     |.| ||.|     ..       | |....|.. .||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KVGT-FVPKVARFFTAEIVLAVNSVHKLGFIHSDLKPDNILIASTGHIKLTDFGIASAYGKSDADYDELLRETQDLMLDNDNPIVPSQTQRHH-HRNSI-
| .  . .|    |   |    .  |. ..|| ||   |.|... ...| .||| . . .  |.                    . ... |.  |...  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG------------------ESKDYYRKKEHKGGKT

IGTVDYIAPEVLRGDPPNVKNDWWSLGVILYEML-YGFTPFSSD----SKNETVFRIINWKKSLRIPAS-----KPVPVSALDLLRHLLC-----DIENR
   .   |||...    . | | || || ..|.. || .| . .     .|. |.. .   . ...|..         | . | .  .       | |.|
MLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDR

YGYEEIIHHAF
   .|| |. |
PTFSEI-HECF
Kinase 90655.m00128.AA S_TK_X 386-444 18 0.000203 14.05 SMART 1-79 (79) Show / Hide 
Range on Protein: 386-444
Range on HMM: 1-79/79
Sequence Identity: 18% (16 aa)

NGFDFENILQ----NKTPVKPICS----DPLDTAHFD-HFDVTKLDLRANGLLTKLANY------------------AFLGFTYKP
 |.|......     . | || ..    .| ||  ||  |.  . .        . ..                    |.||||. 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF