Gene 89882.m00073 (T.vaginalis)

89882.m00073

Species: T.vaginalis
Alias: 89882.m00073, TvagK0937
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: PKR-like

Sequence

Name Sequence Type Origin Length Description Download
89882.m00073.AA Protein None 364 None Fasta, JSON
89882.m00073.kin_dom Protein Kinase Domain None 273 None Fasta, JSON

Protein domain

Protein domains of 89882.m00073.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89882.m00073.AA PEK 186-358 22 7.9e-41 139.55 In-house 358-655 (655) Show / Hide 
Range on Protein: 186-358
Range on HMM: 358-655/655
Sequence Identity: 22% (66 aa)

FYIQMELCSKMPVSKLCQ-----------------------------------------------SIEPISVLAKARDVAEGLAYIHQMGIVHRDIKPSN
.|||||.|.|   . . .                                               ...   ..  .|...|||.|||..|..|||.||||
LYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSN

ILIGMDGE-----PKIADFGISI-----------------------NTDSINEIAMESS-----------------------------------TELYAS
|.. .||       ||.|||...                       ..|. ...  ...                                   | ||.|
IFLDCDGQHHQMQVKIGDFGLATNHEMLSQSQKNYNQQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMWSNNYHIQPTSMFYCEHCHHTGGVGTCLYMS

PEHYDST-----KISDKSDIYSLGLTMFDLFVRPKTKM-EHIKTMVNLRK-NRVFPDDFP------DIPKLKELICHMIEEEPEDRPSAEEVI--DFL
|| .. .     .   |.|.||||.  | ......| | | .||. .||. .  ||.|||      . ||....| .|.   |..||||..    .|.
PEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFTTMMERVKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Pkinase 89882.m00073.AA Pkinase 86-358 20 5.2e-40 142.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 86-358
Range on HMM: 1-293/293
Sequence Identity: 20% (66 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKITIDYDPEECD-SLFN--ETKIMAKINHKNVVRYYAPWVEFDISDSNILPIEYSEDHKGKISKRKGGKI
|.|..|||.|   .||   |  . .|.|||.|  . . ...| ....  | .||...||.|.||.|  . .                             
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-----------------------------

HCSFYIQMELCSKM----PVSKLCQ-----SI--EPISVLAKARDVAEGLAYIHQMGIVHRDIKPSNILIGMDGEP----KIADFGISIN--TDSINEIA
. . |. ||.| .       . . .     ..  ..  .   .. ...||.|.|.|||.|||.||.||||  .|..    ||.|||..    . .     
KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT

MESSTELYASPEHYD-STKISDKSDIYSLGLTMFDLFV-----RPK----TKMEHIKTMVNLRKNRVFPDDFPDI--------------------PKLKE
    |  |..||    ..... |.|..|.|.... ..      . .    . ..... ... .. ..  | . ..                    . .|.
TFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKD

LICHMIEEEPEDRPSAEEVIDF--L
.|. ...  |..||.||..     .
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89882.m00073.AA TKL 92-358 18 3.4e-36 126.56 In-house 1-364 (364) Show / Hide 
Range on Protein: 92-358
Range on HMM: 1-364/364
Sequence Identity: 18% (73 aa)

IGEGLNCEVYSVLHLVDK--------HIYAVKKITIDY-----------------------DPEEC---DSLFNETKIMAKINHKNVVRYYA-----PW-
||.|  .|||   .               ||||. ...                       ||| .   . . .|...| ...| |.|....     |. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------VEFDISDSNILPIEYSEDHKGKISKRKGGKIHCS---FYIQMELCSKMP-VSKLCQSIEPISVLAK-ARDVAEGLAYIHQMG--------IVHR
      |                                .   ..| ||.|..    . |      .... . |.|.| |..| |.|.        |.||
CVCMHPV-------------------------------GPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHR

DIKPSNILIGMDGE--------------PKIADFGISINTDSINE-------------------IAMESS-TELYASPEHYDST----------------
|.|..|||.  ...              .||.|||.| . .  ..                     |    |  . .||  . .                
DLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGF

KISDKSDIYSLGLTMFDLFV--RPKT--KMEHIK---------TMVNLRKNRVFPD----------DFPDIPK-LKELICHMIEEEPEDRPSAEEVIDFL
. | |.|.|| |. .. ..   ||    ... ..          || ....|  ..          . ||.|. .|.|. .  ...||.|||..|... |
EYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
S_TKc 89882.m00073.AA S_TKc 86-362 21 1.4e-34 122.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 86-362
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKITIDYDPEECDSLFNETKIMAKINHKNVVRYYAPWVEFDISDSNILPIEYSEDHKGKISKRKGGKIHCS
|.||.|||.|   .|| . |  ...|.|.|.|         ... .| .|. | .|.|.|..|  ...                               .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD------------------------------DH

FYIQMELCSK--MPVSKLCQS---------IEPISVLAKARDVAEGLAYIHQMGIVHRDIKPSNILIGMDGEPKIADFGISINTDSINEIAMESSTELYA
.|. ||.|.     . .. ..         . .  .   .. ....|.|.|..||.|||.||.|||.    . ||.|||..              |  | 
LYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYM

SPEHYDSTKISD-KSDIYSLGLTMFDLFV-RPKTKMEHIKTMVNLRKNRVFPDDFPDIPKLKELICHMIEEEPEDRPSAEEVID-----FLSEII
.||     . .  |.|..|.| ... ... .|     ....| .. .           | .|..|... . .||.||.| |.        . . .
APEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89882.m00073.AA GCN2 187-353 24 1e-29 100.97 In-house 283-504 (511) Show / Hide 
Range on Protein: 187-353
Range on HMM: 283-504/511
Sequence Identity: 24% (55 aa)

YIQMELCSKMPVSKLCQSIEPISVLA----KARDVAEGLAYIHQMGIVHRDIKPSNILIGMDGEPKIADFGISIN-------------------------
||||| |..  .. .  .  ...  .     .|.. |||.|||..|..|||.|||||..  .|  ||.|||...|                         
YIQMEYCEGKTLRQYIDNHGWCMDHDELWRYFRQILEGLNYIHSQGMIHRDLKPSNIFLDCCGNVKIGDFGLATNNKMESQINRKQQKQQQQASSHWAIQ

--------TDSINEIAMESS-------------TELYASPEHYDSTKISDKSDIYSL-GLTMFDLFVR-PKTKMEHIKTMVNLRKNRVFPDDFP-----D
        . ..   . ...             | .| .||   . .  .| |.||| |.  | .. .   |.|| ...  .|| .  ||.||.     .
NEICQDDQFNQQQSQFSQWDQQDEQVHHTGKVGTPFYMCPEQQ-KSHYNQKVDMYSLGGIIFFEMWYPPFCTQMERVQILKQLR-SCEFPQDFDKKVDNH

IPKLKELICHMIEEEPEDRPSAEE
 .. ...|  ..   |  ||||..
HKDQQDMIRWCLNHDPQKRPSAQQ
Kinase 89882.m00073.AA PKR 86-358 28 3.2e-27 94.47 In-house 1-272 (272) Show / Hide 
Range on Protein: 86-358
Range on HMM: 1-272/272
Sequence Identity: 28% (80 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKITIDYDPEECDSLFNETKIMAKINHKNVVRYYAPWVEFDISDSNI-LPIEYSEDHKGKISKRKGGKIHC
.. .|.|| |    |.   | .|   |..|.  . |  |  .    | . .||..| |.|.| . |  ||         .| |.      .     | .|
FKDIEEIGSGGFGQVFKAKHRIDGKRYVIKR--VKYNNEKAE---HEVQALAKLDHVNIVHYHSCWDGFDYDPEHSDDSLESSDYDPENMKDTSRYKTRC

SFYIQMELCSKMPVSKLCQS-----IEPISVLAKARDVAEGLAYIHQMGIVHRDIKPSNILIGMDGEPKIADFGISINTDSINE-IAMESSTELYASPEH
 | |||| | |  . .  .      .. . .|     . .|  |||  ...|||.||||| .  . . || |||.    .           |  | ||| 
LF-IQMEFCDKGTLEQWMRNRRQEKVDKVLILDLYEQIVKGVDYIHSKKLIHRDLKPSNIFLVDERHIKIGDFGLVTALKNDGKSRTRRKGTLQYMSPEQ

YDSTKISDKSDIYSLGLTMFDLFVRPKTKMEHIKTMVNLRKNRVFPDDFPDIPKLKELICHMIEEEPEDRPSAEEVIDFL
  | .     ||| ||| . .|     |..|.||   .||.  .  | | .  | | |.  .. . |.|||   |..  |
IFSQHYGKEVDIYALGLILAELLHVCFTEFEKIKFFEDLRDGDFSNDIFDN--KEKTLLQKLLSKKPKDRPNTSEILRTL
Kinase 89882.m00073.AA Ciliate-E2 219-356 21 2.2e-26 87.58 In-house 171-361 (365) Show / Hide 
Range on Protein: 219-356
Range on HMM: 171-361/365
Sequence Identity: 21% (44 aa)

EGLAYIHQMG-IVHRDIKPSNILIGMDGEPKIADFGISINTD---------SINEIAMESS------------------------TELYASPEHYDSTK-
..| |.|. . |.||||||.|||.     .||.|||.| . |         ..... |. .                        |  | .|| . . | 
LALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKY

--------ISDKSDIYSLGLTMFDLFVR--PKTKMEHIKTMVNLRKNRVFPDDFPDI--------------------PKLKELICH----MIEEEPEDRP
         . |.||.||| ... .     |            ....   . |||                      .. | ||      |.. .|| |.
DNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI

S-AEEVID
. .|....
TGWEQILN
Kinase 89882.m00073.AA STE 214-353 24 8.3e-23 77.45 In-house 157-350 (359) Show / Hide 
Range on Protein: 214-353
Range on HMM: 157-350/359
Sequence Identity: 24% (48 aa)

ARDVAEG-LAYIHQMGIVHRDIKPSNILIGMDGEPKIADFGISI-NTDSINEI----------AMESS------TELYASPEHYDS------TKISDKSD
.|.. .| |.|.|...|.||||||.|||.      |..|||..   |||. .|           | .       |  . .||  .        . . |.|
CRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCD

IYSLGLTMFDLFV--RPKTKMEHIKTMVNLRKNR-------------VFPDDFPDI---------------------PKLKELICHMIEEEPEDRPSAEE
|.|||.|.  .     |  .| . . | .  .|                |  .||                      |..|. | .  . .|..||.|..
IWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 89882.m00073.AA WEE 187-298 26 5e-21 67.33 In-house 81-227 (297) Show / Hide 
Range on Protein: 187-298
Range on HMM: 81-227/297
Sequence Identity: 26% (39 aa)

YIQMELCSK-------MPVSKL-CQS-IEPISVLAKARDVAEGLAYIHQM-GIVHRDIKPSNILIGMDG--------------------EPKIADFGISI
|||||.| .          . . ..  .. . .    .|...||..||.. |.|| ||||.||.|....                      ||.||| ..
YIQMEYCNGGSNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVT

NTDS---INEIAMESSTELYASPE--H-YDSTKISDKSDIYSLGLTMF
...|   . . . |.  . | .||  . | .   . |.||.|||.|..
DMNSNNNNPHQEQEGDSR-YMAPEILQGYYHYTHLYKADIFSLGITIY
Kinase 89882.m00073.AA PEK 270-360 32 3.8e-19 59.48 In-house 651-758 (758) Show / Hide 
Range on Protein: 270-360
Range on HMM: 651-758/758
Sequence Identity: 32% (35 aa)

TELYASPEHYDST----------------KISDKSDIYSLGLTMFDLFVR-PKTKMEHIKTMVNLRKNRVFPDDFPD-IPKLKELICHMIEEEPEDRPSA
| ||.|||.   .                  . | |||||||  | |..    | || |.|| .|| | ..| .| .  |.  |.|  |.  .|. ||.|
THLYMSPEQCHHQSVFGTGTYTNPEQKKTWYNHKVDIYSLGLIFFELIHPGFSTQMERIRTMCDLR-NGQWPKWFTQKYPQEYEFIQQMMSMNPDERPTA

EEVIDFLSE
 ...  .. 
DQISMHDFF
Kinase 89882.m00073.AA STE20 219-255 56 2.9e-17 59.88 In-house 128-164 (288) Show / Hide 
Range on Protein: 219-255
Range on HMM: 128-164/288
Sequence Identity: 56% (21 aa)

EGLAYIHQMGIVHRDIKPSNILIGMDGEPKIADFGIS
.||.|.|...|.|||||  |||...||| |.|||| .
QGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVC
Kinase 89882.m00073.AA PEK 86-156 25 9.4e-17 54.19 In-house 1-88 (655) Show / Hide 
Range on Protein: 86-156
Range on HMM: 1-88/655
Sequence Identity: 25% (22 aa)

YQILEKIGEGLN-CEVYSVLHLVDKHIYAVKKITIDYDP----------------EECDSLFNETKIMAKINHKNVVRYYAPWVEFDI
.. ....| |   . || | . .|.. ||.|.|....                  . |.. . | | .|. ||.|.|||.. | | ..
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNHPNIVRYHNAWIEKPE
Kinase 89882.m00073.AA STE20 86-148 31 6.3e-14 47.56 In-house 1-70 (288) Show / Hide 
Range on Protein: 86-148
Range on HMM: 1-70/288
Sequence Identity: 31% (22 aa)

YQILEKIGEGLNCEVYSVLHLVDKHI----YAVKKITIDYDP---EECDSLFNETKIMAKINHKNVVRYY
|..|||||.|  ..|| . |   . .    .|.||. .. .    .| .....|  ||.. .|.|.|.||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYY
Kinase 89882.m00073.AA TyrKc 86-358 19 8.7e-14 0.23 SMART 1-280 (280) Show / Hide 
Range on Protein: 86-358
Range on HMM: 1-280/280
Sequence Identity: 19% (61 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKITIDYDPEECDSLFNETKIMAKI--NHKNVVRYYAPWVEFD----ISDSNILPI----------EYSED
 . ..|.|||  .|||           |||..  |        . .| .|| |.  .|.|.|| |.  .  .    ...  .. .          .|  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYG-VCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HKGKISKRKGGKIHCSFYIQMELCSKMPVSKLCQSIEPISVLAKARDVAEGLAYIHQMGIVHRDIKPSNILIGMDGEPKIADFGISINTDSI-------N
|..|                               . .   |  . ..|.| .|.|.....|||.   |.|.| ..  ||.||| | . ..         
HRPK-------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKD

EIAMES--STE--L---YASPEHYDSTKISDKSDIYSLGLTMFDLF---VRPKTK-----MEHIKTMVNLRKNRVFPDDFP--------DIPKLKELICH
 . . .  ..   |     .||  .  | . |||..| | .|. .|     |        |. .  . .... .  |              ... ...  
YYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQ

MIEEEPEDRPSAEEVIDFL
  .|.|||||. .|.....
CWHEDPEDRPTFSEIHECF
Kinase 89882.m00073.AA STE 86-148 23 7.2e-13 41.88 In-house 1-96 (359) Show / Hide 
Range on Protein: 86-148
Range on HMM: 1-96/359
Sequence Identity: 23% (23 aa)

YQILEKIGEGLNCEVYSVLHLV---------------DKHIYAVKKITIDYD----------------PEECDSLFNETKIMAKIN--HKNVVRYY
....||||.|   .||  ..                  . |.|.|.. .. .                .|| ... .| ||| | |  |.|.|.||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYY
Kinase 89882.m00073.AA WEE 86-153 31 8.4e-12 35.94 In-house 1-76 (297) Show / Hide 
Range on Protein: 86-153
Range on HMM: 1-76/297
Sequence Identity: 31% (24 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKI-TIDYDPEECDSLFNETKIMAKIN-------HKNVVRYYAPWVE
.|...|||||   ||| . . .|. |||.||.  .  .. | .. ..| .. ...        |...||||  | |
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEE
Kinase 89882.m00073.AA HRI 86-153 39 4.9e-11 34.33 In-house 1-69 (613) Show / Hide 
Range on Protein: 86-153
Range on HMM: 1-69/613
Sequence Identity: 39% (27 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKITIDYDPE-ECDSLFNETKIMAKINHKNVVRYYAPWVE
.  .| ||.|    || | |  ||  ||.||| |      .| ..  | |..|  .| |.|||   |.|
FEQKEIIGKGGYGRVYKVRHKLDKQHYAIKKIKIKKRTKCSCMKMQREVKVLACLQHHNIVRYHQAWIE
Kinase 89882.m00073.AA HRI 219-253 56 2.2e-10 31.98 In-house 444-482 (613) Show / Hide 
Range on Protein: 219-253
Range on HMM: 444-482/613
Sequence Identity: 56% (22 aa)

EGLAYIHQMGIVHRDIKPSNI-LIGMDG---EPKIADFG
||. ||| |.|||||.|| || | . |      || |||
EGMFYIHNMFIVHRDVKPRNIFLHDPDQGHPQVKIGDFG
Kinase 89882.m00073.AA PEK 218-253 35 7.4e-10 27.84 In-house 452-511 (758) Show / Hide 
Range on Protein: 218-253
Range on HMM: 452-511/758
Sequence Identity: 35% (21 aa)

AEGLAYIHQMGIVHRDIKPSNILIGMDGE------------------------PKIADFG
.||. ||| .|. ||| |||||   ||.                          || |||
CEGVNYIHSKGMIHRDLKPSNIFFSMDSQHHQQSSFSNISSSFEENSDGGHQIIKIGDFG
Kinase 89882.m00073.AA HRI 270-322 37 1.9e-09 28.59 In-house 523-575 (613) Show / Hide 
Range on Protein: 270-322
Range on HMM: 523-575/613
Sequence Identity: 37% (20 aa)

TELYASPEHYDSTKISDKSDIYSLGLTMFDLFVRPKTKMEHIKTMVNLRKNRV
|..|||||  | ..   ||| ||.|. .| ||    | ||  . .  .|  ..
TCTYASPEQLDGSQYDNKSDMYSMGVILFELFQPFGTEMERAEVLTGVRTGQI
Kinase 89882.m00073.AA GCN2 86-179 24 2.8e-08 24.65 In-house 1-110 (511) Show / Hide 
Range on Protein: 86-179
Range on HMM: 1-110/511
Sequence Identity: 24% (27 aa)

YQILEKIGEGLNCEVYS-VLHLVDKHIYAVKKITIDYDPE--ECD-SLFNETKIMAKINHKNVVRYYAPWVE------------FDISDSNILPIEYSED
 .... .| |   .|.. |   .|  .||.||. |... .  .|  . . | |  .. .| .|||||. |.|            .| .. |  .   || 
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRLHHQHVVRYYQAWIEKCDEPMVTDTNNDDDTNNNYHSDDESEC

HKGKISKRKG
 .|.... |.
FSGQYEMPKS
Kinase 89882.m00073.AA Ciliate-E2 86-148 18 4.2e-07 20.42 In-house 1-98 (365) Show / Hide 
Range on Protein: 86-148
Range on HMM: 1-98/365
Sequence Identity: 18% (18 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKITIDY--------------------DPEECDSLFNETKIMAKIN----------------HKNVVRYY
| ...|||.|    || . .  ... .| |.|. ..                     . .  ....| .|| .||                |.|....|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY
Kinase 89882.m00073.AA PEK 86-166 21 1e-06 17.06 In-house 1-109 (758) Show / Hide 
Range on Protein: 86-166
Range on HMM: 1-109/758
Sequence Identity: 21% (23 aa)

YQILEKIGEGLNCEVYSVLHLVDKHIYAVKKITIDY--------DPEECDSLFNETKIMAKINHKNVVRYYAPWVEFD--------------------IS
.   ...| |    |. .   || . ||.|.|| .           .  .    | .  |. .| | |||.  | | .                      
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAMLDHHNIVRYFNAWLETPELLPPNNKMRSTSFSTVNGKQI

DSNILPIEY
|||.  ..|
DSNNDNDIY
Kinase 89882.m00073.AA Pkinase_Tyr 86-149 29 4e-06 21.56 Pfam 1-71 (270) Show / Hide 
Range on Protein: 86-149
Range on HMM: 1-71/270
Sequence Identity: 29% (21 aa)

YQILEKIGEGLNCEVYSVLHL----VDKHIYAVKKITIDYDPEE--CDSLFNETKIMAKI-NHKNVVRYYA
 ....|.|||   |||          .|   |||..  ....|.   .....| ||| .. .|.|.||.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYG
Kinase 89882.m00073.AA Pkinase_Tyr 214-255 30 4e-06 21.46 Pfam 117-158 (270) Show / Hide 
Range on Protein: 214-255
Range on HMM: 117-158/270
Sequence Identity: 30% (13 aa)

ARDVAEGLAYIHQMGIVHRDIKPSNILIGMDGEPKIADFGIS
....|.|..| ......|||.   |.|.. ..  ||.||| .
CWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 89882.m00073.AA WEE 333-353 42 0.001192 8.2 In-house 270-290 (297) Show / Hide 
Range on Protein: 333-353
Range on HMM: 270-290/297
Sequence Identity: 42% (9 aa)

LKELICHMIEEEPEDRPSAEE
||.||  |... || ||....
LKQLIKWMMHPDPEQRPTCQQ
Kinase 89882.m00073.AA Pkinase_Tyr 342-358 41 0.09539 6.54 Pfam 254-270 (270) Show / Hide 
Range on Protein: 342-358
Range on HMM: 254-270/270
Sequence Identity: 41% (7 aa)

EEEPEDRPSAEEVIDFL
...|||||. .|.. .|
HYDPEDRPTFSEIHEQL
Kinase 89882.m00073.AA STE20 331-353 26 0.108847 2.31 In-house 259-281 (288) Show / Hide 
Range on Protein: 331-353
Range on HMM: 259-281/288
Sequence Identity: 26% (6 aa)

PKLKELICHMIEEEPEDRPSAEE
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PEFHDFVDKCLQKDPEKRPTASQ