Gene 87100.m00138 (T.vaginalis)

87100.m00138

Species: T.vaginalis
Alias: TvagK0061, 87100.m00138
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
87100.m00138.AA Protein None 299 None Fasta, JSON
87100.m00138.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of 87100.m00138.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 87100.m00138.AA S_TKc 7-254 31 1.1e-80 275.26 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-231/231
Sequence Identity: 31% (83 aa)

YQLLCPIGEGASSTVYCAKNNDTNDNCCIKLIKKSRSENCFLDIESKVLPTLNHPNIVKFIDFLEDVDNFYLVEELCCG--ETLTHYMESGKI------L
|..| .||.|| ..||......|.  . || ||      . .  | ..|   .||||||..|. .| |..|.| |.| |   .| .|... .       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNANTIKLIDFGLSTDNNSQMRATFCGSVAFASPECINHLNYDSKSADIWSCGVICYYLATGSI
.   . ..|.|...|..|.| .|| ||||| .|| ...  .||..||||..        ||||.  . .|| .    |. ...|.||||.| | ...|  
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYP

PWKGKNIVQIMRSITTVNYTIPSTVSLPVKSIIQQCLQLDPVKRPSASKLLE-------SPFF
|.   .. .... |           | ..|..|..||| || |||.| ..|.        |.|
PFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 87100.m00138.AA CAMK 12-254 18 3.5e-80 257.91 In-house 1-425 (425) Show / Hide 
Range on Protein: 12-254
Range on HMM: 1-425/425
Sequence Identity: 18% (80 aa)

PIGEGASSTVYCAKNNDTN------------DNCCIKLIKKSRSEN-----------------------------CFLDIESKVLPT-------LNHPNI
 .|.|. ..|. ...  |.              . || |.|..  .                              ..  | ... .       |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFIDFLED-------------------VDNFYLVE---ELCCGE----TLTHYMESG---------------KILTDSAILSIMQQLLSAIQYIHYKGI
.|.... ||                    ...|.|    |.| |      |  |  .                . .| .    ...|..||..|.| ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDLKTDNIIISNA-----------------NTIKLIDFGLSTDNNS-------------------------QMRATFCGSVAFAS-PECINH------
 ||||| .|| ...                  |.||.||||...  ..                         |.  ||||. .... || .|       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------LNYDSKSADIWSCGVICYYLATGSIPWKGK-------------NIVQIMRSITTVNYT-IPSTVSL-----------------------PVKS
         |.....|.||||||.| . .|  |. |.             |. .... |.. .|. .|. .|                         .|.
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

IIQQCLQLDPVKRPSASKLLESPFF
 |...|| || ||....  |. |..
LIRKMLQVDPEKRMTIEQCLNHPWM
Pkinase 87100.m00138.AA Pkinase 7-254 29 7.7e-79 273.02 Pfam 1-293 (293) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

YQLLCPIGEGASSTVYCAKNNDTNDNCCIKLIKKSRSENCFLDI-----ESKVLPTLNHPNIVKFIDFLEDVDNFYLVEELCCGE----TLTHYME--SG
|... .||.|....|| ... .|..  ..| |||.. . ... .     | ...  |||||||...|. || |. |.| |.| |      | .|..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KIL--TDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNANTI----KLIDFGLST---DNNSQMRATFCGSVAFASPECINHLNYDSKSADIWSC
. .  ..  . ..| |.|....|.| .|| ||||| .|| |.| ..|    |..||||.      |..   ||||.  ...|| |.. .|.....|.|||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVICYYLATGSIPWKGK----------NIVQIMRSITTVNYTIPSTVS-----------------LPVKSIIQQCLQLDPVKRPSASKLLESPFF
|.|.|....|  |..|.           |..||. ..  ..  ....|                  . |..|  ||..|| |||.|  .|..|.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 87100.m00138.AA CAMKL 7-254 26 7.6e-75 238.24 In-house 1-297 (297) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-297/297
Sequence Identity: 26% (79 aa)

YQLLCPIGEGASSTVYCAKN-NDTNDNCCIKLIKKSRSE-NCFLDI---------------ESKVLPTLN---HPNIVKFIDFLEDVDN------FYLVE
|...  .|.|. ..|  |..   |.    || |.|..   ... .                | . .  ||   ||||.|. . .|. ..      .||| 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCCGET--LTHYM--ESGKI--LTDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNAN--TIKLIDFGLST------DNNSQMRATFCGSVAFA
|.|.|    | .|   . ..   .. .    . .|..||..|.| .|| |||.| .|| ... .  .||.||||.|.      ... |.  ||||| ...
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPECINH--LNYDSKSADIWSCGVICYYLATGSIPWKGKNIV---------QIMRSITTVNYTIPSTVSLPVKSIIQQCLQLDPVKRPSASKLLESPFF
.|| ..     || . .|||||||| | . .|  |... ..            .  ..  ...|.. || .....|.. || .| |||..  ... |..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 87100.m00138.AA MARK 7-254 30 1.3e-73 240.06 In-house 1-262 (262) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-262/262
Sequence Identity: 30% (79 aa)

YQLLCPIGEGASSTVYCAKNNDTNDNCCIKLIK---KSR-SENCFLDIESKVLPTLNHPNIVKFIDFLE--DVDN-FYLVEELCCGETLTHYMESG--KI
| .|  ||.|. ..|. | .  |. . .|| ..   ...  . . .  | ...  |.||||.|. .  |  .  . .||. |...|  | .|...     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNAN--TIKLIDFGLSTDN-NSQMRATFCGSVAFASPECINHLNYDSKSADIWSCGVICYYLA
|. .    | .|..||..| | |.| |||.| .|| |   .   ||.||||.|.   . |.  ||||. ....|| ..   || . .||||.||. |.. 
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

TGSIPWKGKN--IVQIMRSITTVNYTIPSTVSLPVKSIIQQCLQLDPVKRPSASKLLESPFF
.|. |..|..  ...... |.. .|.||. ||   ...||. |...| .||... ... |..
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 87100.m00138.AA Ciliate-E2 7-254 23 7.4e-67 228.42 In-house 1-365 (365) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-365/365
Sequence Identity: 23% (88 aa)

YQLLCPIGEGASSTVYCAKNNDTNDN-----------------------CCIKLIKKSRSENCFLDIESK--------------VLPTLNHPNIVKFIDF
| ..  ||.|. ..|| .|.  .. .                         .| .||.  |. .  |                 .| .||||||.|....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--DVDNFYLVEELCCGETLTHYME------------SGKILTDSAILSIMQQLLS---------------AIQYIHYKG-ISHRDLKTDNIIISNANT
 .  | .|.||| |.| | .| .|..              | .|.  |. ||.|.|.               |..|.| |. | |||.| .||..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLIDFGLSTDNNSQ---------------------------------MRATFCGSVAFASPECINHLNY--------DSKSADIWSCGVICYYLATGSI
||.||||||.... .                                 |  |.||.  . .|| .|  .|         ....||||.||| |.. .|  
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PWKGKNIVQIMRSITTVNYTIP------------------STVSLPVKSIIQQ----CLQLDPVKRPS-ASKLLESPFF
|.        .. |   .. .|                    .|. .| .|..    .|| || ||.. ....|. |.|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 87100.m00138.AA CAMK-Unique 7-254 23 2.6e-64 211.16 In-house 1-363 (363) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-363/363
Sequence Identity: 23% (85 aa)

YQLLCPIGEGASSTVYCAKNNDTNDNCCIKLIKKSRSENCFLDI---------------------ESKVLPTLNHPNIVKFIDF----LEDVD-------
| .. .||.|. . || ...  | . . .|..|| . .|  ...                     |  .. ...||||.|. |.     .| .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NFYLVEELCCGETLTHYMES--------------------GKILTD--SAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNA-------
        ..|.| |.| | .|  .. .                      ...   . ...|||.||||. | | ..| ||||| .|| ...        
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

---------NTIKLIDFGLSTDNN-SQMRA---TFCGSVAFASP--------------ECINHLNYDSKSA---DIWSCGVICYYLATGSIPWKGKNIV-
         . |||.||||... | ..|..   |.||.  ...|              | ||   ||...    ||||.||| ||...|. |  . ..  
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

-------QIMRSITTVNY-TIPS-----T--VSLPVKSIIQQCLQLDPVKRPSASKLLESPFF
        | ..|.  .| . ..     .  .|   |.....|...||..| ||. |||....
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 87100.m00138.AA Ciliate-E2-Unclassified 7-254 23 2.9e-61 209.84 In-house 1-352 (352) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-352/352
Sequence Identity: 23% (84 aa)

YQLLCPIGEGASSTVYCAKNNDTNDNCCIKLIKKSRSEN-CFL-----------DIESK--------------VLPTLNHPNIVKFIDFLEDVDNFYLVE
| ..  ||.|. ..|| .......    .| .||... . .              ...|               |  ..||.|||...  .| .|.|.| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELCCGETLTHYMES-----------------GKILTDSAIL-----SIMQQLLSAIQYIHYKG-ISHRDLKTDNIIISNAN---TIKLIDFGLSTDNN--
|.| | .|  |...                 .||.|. ...      .. |.|....|.|.|. | |||.| .||...| .    ||.||||.|  ..  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------SQMRATFCGSVAFA----SPECINHLNYDS---KSADIWSCGVICYYLATGSIPWKGKNIVQ----------------IMRSITT
               .||  ||||.  .     .||..   |||    ...||||.|||.|.. .|  | ...|  |                . . |  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

VNYTIPS--------TVSLPVKSIIQ----QCLQLDPVKRPSASKLLESPFF
 |. .|.        ..|  .| .|.    ..|. .| ||......|. |.|
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 87100.m00138.AA Ciliate-E2a 7-254 32 5.2e-60 175.33 In-house 1-275 (275) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-275/275
Sequence Identity: 32% (90 aa)

YQLLCPIGEGASSTVYCAKNNDTNDN-CCIKLIKKSRSEN---CFLDIESKVLPTLNHPNIVKFIDFLEDVDNFYLVEELCCGETLTHYMESGKILTDS-
| ..  ||.|.   || |.  .|...   .|.||| . .     ..  | . . .|.|||| |.... || .|.||| |.| | .| ...   | ..   
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-AILSIMQQLLS-AIQYIHYKGISHRDLKTDNIIIS--NANT-----IKLIDFGLSTDN--NSQ-MRATFCGSVAFAS------PECINHLNYDSKSADI
  | .||||||. ...|.| ..| ||||| .||..   ..|      ||.|||||.|.   ...  . . ||.  .        .| ..| .|| |  |.
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKC-DM

WSCGVICYYLATGSIPWKGKNIVQIMRSI--TTVNYTIPS---TVSLPVKSIIQQCLQLDPVKRPSASKLLESPFF
|||||| | | .|. | |||.  .|  ..     .. .|     .|.. | .... |. || ||..|  .|..|.|
WSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 87100.m00138.AA ULK 7-254 23 3e-59 203.17 In-house 1-324 (324) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-324/324
Sequence Identity: 23% (77 aa)

YQLLCPIGEGASS-TVYCAKNNDTND-N----C---CIKLIKKSRSEN------CFLDIESKVLPTLN---HPN--IVKFIDFLEDV--DNFYLVEELCC
|.|   .|.|.   .|| ..|..||. |    |    .| ..|. .|.      ..|. | ... .|.   |||  |||..|..|.   .|.|.. |.| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GETLTHYME---------SGKILTDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNAN------------TIKLIDFGLSTDNNS-----QMRAT
| .| .|..          .|.|. . ......|.... ...| ..| |||.| .|| |.| .            ..|. |||..   ..     ||. |
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

FC------GSVAFASPECIN----HLNYDSKSADIWSCGVICYYLATGSIP---WKGKNIV----QIMRS-------ITTVNYTIP-----STVSLPVKS
..      |.  . .|. ..    . .|... .|||| |.| |.. .|. |   |   . .    .  .        | . .  .|       .|  .|.
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

IIQQCLQLDPVKRPSASKLLESPFF
.|...|| |. .| |   ... |.|
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 87100.m00138.AA ULK 7-254 24 4.6e-59 202.55 In-house 1-329 (329) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-329/329
Sequence Identity: 24% (80 aa)

YQLLCPIGEGASSTVYCAKNNDT----NDNCCIKLIK---KSRSE--------NCFLDIESKVLPTLN--------HPNIVKFIDFLEDV--DNFYLVEE
|.|   .|.|.  .|| ..|..|    |  . .| |    .....         ..|. | |.. .|.        ||||||..|..|.   .|.|.. |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCCGETLTHYME----------SGKILTDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNAN------------TIKLIDFGLSTD-NNS----Q
.| | .| .|..           .|.|. . ......|.|.. ...| ..| |||.| .|| |.| .            ..|. |||..   .|.    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

MRATFC------GSVAFASPECIN----HLNYDSKSADIWSCGVICYYLATGSIP---WKGKNIV-QIMRS-----------ITTVNYTIP-----STVS
|  |.       |.  . .|. ..    . .|... .|||| |.| |.. .|  |   |     . ||...           | . .  .|      ..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

LPVKSIIQQCLQLDPVKRPSASKLLESPFF
  .|..|...|| |. .| |   |.. |.|
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 87100.m00138.AA STE 7-254 24 1.5e-55 190.83 In-house 1-359 (359) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-359/359
Sequence Identity: 24% (89 aa)

YQLLCPIGEGASSTVYCAKNN------DTNDN---------CCIKLIKKSRS-----------------ENC-FLDIESKVLPTLN--HPNIVKFIDFLE
....  ||.||. |||.|.|.      .|. .         . || ......                 |.   .  | |..  .|  ||||||...  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DV-------DNFYLVEELCCGETLTHYME----SGKILT----------DSAILSIMQQLLSA-IQYIHYKGISHRDLKTDNIIISNANTIKLIDFGLST
.        |. ... |.. | .|.  ..     || |.           | |  | .|.| .  .|.| ..| |||.| .|| .     .||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

DNNS------------------QMRATFCGSVAFASPECINH------LNYDSKSADIWSCGVICYYLATGSIPWKGKNIVQIMRSITTVN---------
  ..                  |.| ||.|.  . .|| |.         || | .|||| |  .  .|||  ||   .  . |  |.. .         
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTK-CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-------YTIPS-------------------TVSLPVKSIIQQCLQLDPVKRPSASKLLE--SPFF
        ..|.                    .| . |  |..||| || |||.||.||.   ||.
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 87100.m00138.AA TyrKc 7-254 23 3e-16 40.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 7-254
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YQLLCPIGEGASSTVYCAKNNDTNDNCCIKLIKKSRSENCFLDIESKVLPTL--NHPNIVKFIDFLEDV-------DNFYLVEELCCGETLTHYMESGKI
 .|.  .||||  .|| .. .    .. .| .|..  .  |.. | ...  |  .|||||...    .        .  ..| |....  | .|  . . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMR-EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-LTDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNANTIKLIDFGLSTDNNSQ---------MRATF--CGS----VAFASPECINHLNYDSKSA
 |. .  ||.. |  .  .|.| |.. |||| . |. ... .|.|  ||||| |  .           |..   .|     .   .|||||.  . .|| 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-

DIWSCGVICYYLAT-GSIPWKG-----KNIVQIMRSITTVNYTIPSTV---------SLPVKSIIQQCLQLDPVKRPSASKLLESPFF
|.|| || .. . | |  |. |     ..  .... . . ..  .            .  . .|..|| . || .||. | .    .|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 87100.m00138.AA Pkinase_Tyr 7-250 25 7.9e-15 50.85 Pfam 1-268 (270) Show / Hide 
Range on Protein: 7-250
Range on HMM: 1-268/270
Sequence Identity: 25% (68 aa)

YQLLCPIGEGASSTVYCAKNN----DTNDNCCIKLIKKSRSENC-----FLDIESKVLPTL-NHPNIVKFIDFLE-DVDN--FYLVEELCCGETLTHYME
 ...  .||||  .|| .. .    .|.  . .| .| . ..       |.  | |.. .| .|||||...     . .    |.| |....  | .|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

S----GKILTDSAILSIMQQLLSAIQYIHYKGISHRDLKTDNIIISNANTIKLIDFGLSTDN-----N-SQMRATFCGSVAFASPECINHLNYDSKSADI
.    .. || . .|.. .|  .. .| . |.. |||| . |. ... |..|  ||||. |         .   .    .   .|||||.  . .|| |.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKS-DV

WSCGVICYYLAT-GSIP-WKGKNIVQIMRSITTVNYTIPSTV--SLPVKSIIQQCLQLDPVKRPSASKLLE
|| || .. . | | .| ..|    .... |.  .|  |     . .. ....|| . || .||. | ..|
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHE