91714.m00091

Species: T.vaginalis
Alias: 91714.m00091, TvagK1016
External Links:
Annotation:

Classification

Group: PKL
Family: RIO
Subfamily: RIO2

Sequence

Name Sequence Type Origin Length Description Download
91714.m00091.AA Protein None 351 None Fasta, JSON
91714.m00091.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of 91714.m00091.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91714.m00091.AA RIO2 70-274 37 4e-63 214.1 In-house 1-211 (260) Show / Hide
Range on Protein: 70-274
Range on HMM: 1-211/260
Sequence Identity: 37% (79 aa)

YQLTKQGYDFLALHALVKRNTLSNIGPLVGQGKEADVYVAYDNEGKPVIIKFHRIGRVSFRKAKDTREYLSGKHTSSWLYLSRLSAQREFLNMQGLAHLG
| ||  |||.|||  |  |     .|  .| ||| |.|   . .| ..|.|||| || ||.  |  | |.  .|  ||.|||||||  |.  |. |   .
YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN

FPVPQAIDHNRHCVVMSHIDGTLLNNVQKLEDPEKVFNEIIDTTVNLLKIGIVHADLTQFNIIVKDDLS------ICIIDFPQCLRYTDPEAEEKFNHDL
||||. || ||| |||. | |  . . .. ..| .|. .     | |   | .| |   ||....| .       . .|||||.     ..|.  |  | 
FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPYVYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCGFIMIDFPQMVSTQHQNAQWYFDRDV

NELREFFHNRM
   . ||  |.
DCIHRFFMKRF

Kinase 91714.m00091.AA RIO 70-270 28 5.6e-49 166.09 In-house 1-230 (276) Show / Hide
Range on Protein: 70-270
Range on HMM: 1-230/276
Sequence Identity: 28% (65 aa)

YQLTKQGYDFLALHALVKRNTLSNIGPLVGQGKEADVYVAYDNEGK-----------PVIIKFHRIGRVSFRKAKDTRE---YLSGKHT-SSWLYLSRLS
| .|  .|. ...  .| |  .  .|  .| |||.|.| ... .|.           ...||.|| || ||.  |  |    |.   |  ..|.|..||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW

AQREFLNMQGLAHLGFPVPQAIDHNRHCVVMSHIDG-------TLLNNVQKLEDPEKVFNEIIDTTVNLLKIG-IVHADLTQFNIIVKDDLS------IC
|  |. ||  |   |||.|  || .|| .||. | .         . .  ..|.. .|. . .   . |  ..  ||.|.  ||....|..       . 
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFY

IIDFPQCLRYTDPEAEEKFNHDLNELREFF
.|||||.   . | |.. |  |    . ||
MIDFPQMVEHDHPHALWYFRRDCKCVNMFF

Kinase 91714.m00091.AA RIO1 105-274 31 7.4e-48 149.71 Pfam 1-189 (200) Show / Hide
Range on Protein: 105-274
Range on HMM: 1-189/200
Sequence Identity: 31% (60 aa)

DVYVAYD-NEGK-PVIIKFHRIGRVSFRKAKDTREYLSG----KHTSSWLYLSRLSAQREFLNMQGLAHLGFPVPQAIDHNRHCVVMSHID---GTLLNN
.||.||.  .|| ....|..|.|. .|.| |  |.|       .| ..|.|..|..| .|| |.. ..  |.|.|..||.|||..||. |.   |  . .
NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR

VQKLE--------DPEKVFNEIID-TTVNLL-KIGIVHADLTQFNIIVKDDLSICIIDFPQCLRYTDPEAEEKFNHDLNELREFFHNRM
.  .|        ..| .. |||. .   .. . |.||.|| ..||.| ||  . |||.||      | |.| .  | . . .||  ..
LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKG

RIO 91714.m00091.AA RIO 63-289 22 1.2e-45 158.94 SMART 1-253 (253) Show / Hide
Range on Protein: 63-289
Range on HMM: 1-253/253
Sequence Identity: 22% (58 aa)

QGKPYDGYQLTKQGYDFLALHALVKRNTLSNIG--PLVGQGKEADVYVA----YDNEGKPVIIKFHRIGRVSFRKAKDTRE-YLSGK---HTSSWLYLSR
  . |..|... .... ..| ..|.|.....|.   ... ||||.||.|    .| .|... .|..|... .|.. .  .. . . |   |...|....|
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKMVR

LSAQREFLNMQGLAHLGFPVPQAIDHNRHCVVMSHIDG-----TLLNNVQKL-EDPE---KVFNEIIDTTVNLLKIG-IVHADLTQFNIIVK-----DDL
|.| .|| |.| ..  |.|.|..|. .|| .||. |..       |..|..  ....   .... |..  . . ... .||||| ..|....     .| 
LWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDENDC

SICIIDFPQCLRYTDPEAEEKFNHDLNELREFFHNRMDITVE--HLPTFAEFKD
 . |||..|.   . |...| .  | .  . ||  |. ....      | ....
KVWIIDWSQSVECDHPMWLEFLERDIWNIINFFR-RKGVDCDDIYREIFERITG

Rio2_N 91714.m00091.AA Rio2_N 8-88 55 3.4e-40 137.99 Pfam 1-84 (84) Show / Hide
Range on Protein: 8-88
Range on HMM: 1-84/84
Sequence Identity: 55% (47 aa)

LKYIEEDVWRVLTAVELGQRNHELVAGELIASIAGLR--GTIHHDIDYLLRHKLISH-QGKPYDGYQLTKQGYDFLALHALVKR
..|.... .||||||| | ||||.|  |||..|..||  | .|. .. |..|||||| |.|.||||.||  |||.||||..|||
MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR

Kinase 91714.m00091.AA S_TKc 92-343 13 0.000772 -120.62 SMART 1-231 (231) Show / Hide
Range on Protein: 92-343
Range on HMM: 1-231/231
Sequence Identity: 13% (40 aa)

SNIGPLVGQGKEADVYVAYDNE-GKPVIIKFHRIGRVSFRKAKDTREYLSGKHTSSWLYLSRLSAQREFLNMQ----GLAHLGFPVPQAIDHNRHCVVMS
  |. ..|.|  . || ..... |. | ||  .                              ...||   ..     . .|          .. ..|| 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------EHIRREIQILKKHHPNIVKLYDVFQD----DHLYMVME

HIDG---TLLNNVQK---------LEDPE--KVFNEIIDTTVNLLKIGIVHADLTQFNIIVKDDLSICIIDF-----------------PQCLRYTDPEA
..||   .|.   .|         .   .  ... .|..    . . ||.| ||   || . .   | |.||                 |  |       
YCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQLTTFCGTPWYMAPEVL-------

EEKFNH-------------DLNELREFFHNRMDITVEHLPTFAEFKDDIVPVDIIGKGKPQEEEEDENEDEDKKIMAKVSK---ENRKKNKPVRS--KES
  ....              .   .  |.  |. . ...                              .| | .. |  .   |.|     .     . 
--GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

KSMSRL
|..  .
KCHPWF