Gene 83396.m00075 (T.vaginalis)

83396.m00075

Species: T.vaginalis
Alias: 83396.m00075, TvagK0991
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
83396.m00075.AA Protein None 350 None Fasta, JSON
83396.m00075.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 83396.m00075.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83396.m00075.AA Ciliate-E2-Unclassified 18-267 17 6.4e-20 65.8 In-house 1-352 (352) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-352/352
Sequence Identity: 17% (61 aa)

YSFVKELTSGALNGSWKAVNKNNQNFY-----AIKSILKTSFQTPE-----QNAKFLNEIY-------------ILKQVNNKYIASLVDLIDDSNAYHVV
| ..| . .|. .  .|...|... .|     ..|.. . . |  .     ...| .|..              ||.. .. .|  ...   | .    |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TELPEGVCLREYIETNGP-----------------LSEKSVK-----DIIAK-LFYIAYYTREQLGFKYCNINAENIYVDSNG---TMTKYLLGS-----
.|. ||  |..||. ..                  ..|. .|     ...|  |  . |. ... .. . .|  ||| .|.||         .|.     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----------------ESSISSSANNPKIIP-FLAPEFLSTQKFHPN----SDTWCFGCITFFSLTTRIPFLGATPEA----------------TIKAI
                 .  ... . .|  .|  .||| |  |.        .| |..|.| .. |. . || . . |                  .. |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LTS------HET--IPDTVSEPGKQFIE----RCLIKNPLMRLNLNDLYSVSFL
.        ..   ||...|. .| ||.    ..| |||  |......    ..
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 83396.m00075.AA S_TKc 18-267 20 3.2e-16 61.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-231/231
Sequence Identity: 20% (57 aa)

YSFVKELTSGALNGSWKAVNKNNQNFYAIKSILKTSFQTPEQNAKFLNEIYILKQVNNKYIASLVDLIDDSNAYHVVTELPEG--VCLREYIETNGP---
| ..... .||    .|...|. .  .||| |            ....|| |||. . ..|  | | ..| . ...|.|. .|    |..||. .|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LSEKSVKDIIAKLFYIAYYTREQLGFKYCNINAENIYVDSNGTMTKYLLGSESSISSSANNPKII---------------PFLAPEFLSTQKFHP-N
   ..|  .. ... ..    |  .. |. .. .  ||| .|.                    . ||.                ..||| |   .. .  
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--------------------HIKICDFGLARQLTTFCGTPWYMAPEVL---GYGKCK

SDTWCFGCITFFSLTTRIPFLGATPEATIKAILTSHETIPDTVSEPGKQFIERCLIKNPLMRLNLNDLYS-------VSFL
.| | .||| .  |. . ||   ......| |.          |...|.||..|| |.|  |.   ..           ..
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83396.m00075.AA Pkinase 18-122 25 7.3e-12 43.03 Pfam 1-114 (293) Show / Hide 
Range on Protein: 18-122
Range on HMM: 1-114/293
Sequence Identity: 25% (29 aa)

YSFVKELTSGALNGSWKAVNKNNQNFYAIKSILKTSFQTPEQNAKFL-NEIYILKQVNNKYIASLVDLIDDSNAYHVVTELPEGV----CLREYIE--TN
| ... . ||.    .|...|...  .|.| | | .    .. .... .||.|.| .| ..|  | |   |.. ...|.|. ||      | .||.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPL--SEKSVKDII
|..  ||. .|...
GCFYFSEWECKFYM
Kinase 83396.m00075.AA CAMK 34-122 13 1.6e-11 32.67 In-house 12-185 (425) Show / Hide 
Range on Protein: 34-122
Range on HMM: 12-185/425
Sequence Identity: 13% (23 aa)

KAVNKNNQ------------NFYAIKSILKTSFQ-------------------------TPEQNAKFLNEIYILKQ-------VNNKYIASLVDLIDDSN
....||..              .||| | |.  .                         .|.  .....|| |.|.       .. . | .| . ..|..
LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPH

A-------------------YHVVT---ELPEGVCL----REYIETNGP---------------LSEKSVKDII
                    .. |.   |. .| .|     .||  .|.               ..|. .. ..
YFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYF
Kinase 83396.m00075.AA AGC 197-267 17 4.1e-11 23.48 In-house 287-395 (395) Show / Hide 
Range on Protein: 197-267
Range on HMM: 287-395/395
Sequence Identity: 17% (19 aa)

WC--FGCITFFSLTTRIPFLGATPE----------ATIKAIL------TSHETIP----------DTVSEPGKQFIERCLIKNPLMRLN----------L
|.  .||. .  || . || | .|.           . . |.      .  ...|          . .|.  | .|...| |.|  ||            
WSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGA

NDLYSVSFL
... .  . 
EEIKNHPWF
Kinase 83396.m00075.AA SNRK 181-267 29 4.3e-11 32.3 In-house 167-254 (254) Show / Hide 
Range on Protein: 181-267
Range on HMM: 167-254/254
Sequence Identity: 29% (26 aa)

APEFLSTQKFH-PNSDTWCFGCITFFSLTTRIPFLGATPEATIKAILTSHETIPDTVSEPGKQFIERCLIKNPLMRLNLNDLYSVSFL
||| |   ..  |  | |  | | .  .  . ||  |    |.  |.    |.|| ||.  .. |.. |...|  |  |... | |..
APEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFQEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV
Kinase 83396.m00075.AA Ciliate-E2a 18-130 27 4.6e-11 28.84 In-house 1-117 (275) Show / Hide 
Range on Protein: 18-130
Range on HMM: 1-117/275
Sequence Identity: 27% (32 aa)

YSFVKELTSGALNGSWKAVNKNNQNFYAIKSILKTSFQTPEQNAKFLNEIYILKQVNNKYIASLVDLIDDSNAYHVVTELPEGVCLREYIETNG-PLSE-
|.|.|.. .|. .   .|  |..   .|.| . |   |. .....| ||| |..|.... |  | .   | | |  |.|. ||  | ..|  ..   .| 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

KSVKDIIAKLFY--IAY
. ..||. .|..  ..|
QEICDIMQQLLWQGLHY
Kinase 83396.m00075.AA CAMK 178-267 15 5.8e-11 30.82 In-house 284-425 (425) Show / Hide 
Range on Protein: 178-267
Range on HMM: 284-425/425
Sequence Identity: 15% (22 aa)

PFLA-PEFLST-------------QKFH-PNSDTWCFGCITFFSLTTRIPFLGA-------------TPEATIKAILTSHET-IPDT-------------
.. | || |.              .. . | .| |  |.|... |. . || |              ... . . |..   . .|.              
EYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWW

----------VSEPGKQFIERCLIKNPLMRLNLNDLYSVSFL
          ||.  |..| ..| ..|  |... .  .  ..
DDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 83396.m00075.AA Ciliate-E2 178-267 17 1.7e-10 32.26 In-house 252-365 (365) Show / Hide 
Range on Protein: 178-267
Range on HMM: 252-365/365
Sequence Identity: 17% (21 aa)

PFLAPEFLSTQK---------FHPNSDTWCFGCITFFSLTTRIPFLGATPEATIKA-ILTSHET--------------IPDTVSEPGKQFIER----CLI
...||| |. .|             .| |..|.| .. |. . ||     .  ||   .   .               ... .|. .|..| .    .| 
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQ

KNPLMRLN-LNDLYSVSFL
|.|  |..  ...    ..
KDPEKRITGWEQILNHPWF
Kinase 83396.m00075.AA PLK1 179-267 26 3.6e-10 29.36 In-house 165-253 (253) Show / Hide 
Range on Protein: 179-267
Range on HMM: 165-253/253
Sequence Identity: 26% (24 aa)

FLAPEFLSTQKFHPNSDTWCFGCITFFSLTTRIPFLGATPEATIKAILTSHETIPDTVSEPGKQFIERCLIKNPLMRLNLNDLYSVSFL
..||| |. .      | |  ||| .  |  . ||   . . | . |     .||. .|.| .|.|.. | ..|  | . . . .  |.
YIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase 83396.m00075.AA MARK 34-116 25 5e-10 29.16 In-house 17-104 (262) Show / Hide 
Range on Protein: 34-116
Range on HMM: 17-104/262
Sequence Identity: 25% (22 aa)

KAVNKNNQNFYAIKSILKTSFQTPEQNAKFLNEIYILKQVNNKYIASLVDLID--DSNA-YHVVTELPEGVCLREYIETN--GPLSEK
.|..|. .  .||| . |.. . |..  ..  || |.|... ..| .| . |.  ...   ... |. .|  |..||.    |.|.|.
LACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEE
Kinase 83396.m00075.AA Pkinase 177-267 22 8.3e-10 35.75 Pfam 175-293 (293) Show / Hide 
Range on Protein: 177-267
Range on HMM: 175-293/293
Sequence Identity: 22% (27 aa)

IPFLAPEFLS-TQKFHPNSDTWCFGCITFFSLTTRIPFLGA------TPEATIKAILT----SHETIPDTVS-----------------EPGKQFIERCL
....||| .   |.  | .| | .||| .  |. | || |.      .. . |. |.     ...  ....|                 |..|.||..||
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

IKNPLMRLNLNDLYSVSFL
 |.|  |..  ..    ..
CKDPKKRPTAEQILQHPWF
Kinase 83396.m00075.AA STE 194-267 18 1.2e-08 26.83 In-house 249-359 (359) Show / Hide 
Range on Protein: 194-267
Range on HMM: 249-359/359
Sequence Identity: 18% (21 aa)

SDTWCFGCITFFSLTTRIPFLGATPEATIKAIL----------------TSHETIPD-------------------TVSEPGKQFIERCLIKNPLMRLNL
.| |..||     .| . |.   .|   . .|.                  . ..||                    .|.. |.||..||.|.|  | . 
CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA

NDLYS--VSFL
..| .   .|.
SQLLKSEHPFI
Kinase 83396.m00075.AA TyrKc 18-267 14 3e-08 -89.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-267
Range on HMM: 1-280/280
Sequence Identity: 14% (45 aa)

YSFVKELTSGALNGSWKAVNKNNQNFYAIKSILKTSFQTPEQNAKFLNEIYILKQV--NNKYIASLVDLIDDS-------NAYHVVTELPEGVCLREYIE
 .. |.| .||    .|.. |      |.|.. . .       . |..|. |....  ... |  |.  . ..         . .|.|. .. .|..|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TNGPLSEKSVKDIIAKLFYIAY-------YTREQLGFKYC--NINAENIYVDSNGT-------MTKYLLGS------ESSISS----SANNPKIIPFLAP
 ..|          ..| ....       |  ..   ..    . | |. |..|.|       .....         .. ...    ... .  |  .||
KHRPK------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EFLSTQKFHPNSDTWCFGCITF--FSLTTRIPFLG-----ATPEATIKAILTS-HETIPDT--------VSEPGKQFIERCLIKNPLMRLNLNDLYSVSF
| . . || . || | ||   .  |..    |  |      ...  |. . .     .|.          ..   | ...|   .| .| . ...  ...
ECINYGKFTTKSDVWSFGVCMWEIFTY-GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC

L
.
F
Kinase 83396.m00075.AA Ciliate-E2 18-130 18 3.2e-08 24.32 In-house 1-175 (365) Show / Hide 
Range on Protein: 18-130
Range on HMM: 1-175/365
Sequence Identity: 18% (33 aa)

YSFVKELTSGALN-----GSWKAVN------------------KNNQNFYAIKSILKTSFQTPEQNAKFLNEIY----------ILKQVNNKYIASLVDL
| |.| . .|.         ||  .                  |.....||.|.. |   .  .|  . ..||           ||.|.|...|  ... 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ID--DSNAYHVVTELPEGVCLREYIETN-----------GPLSEKSVKDIIAKLFY----------------IAY
    | | .  |.|. .|  |..||. |           ....|| .|.|......                . |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEY
Kinase 83396.m00075.AA CAMK-Unique 192-267 20 5.5e-07 18.89 In-house 272-363 (363) Show / Hide 
Range on Protein: 192-267
Range on HMM: 272-363/363
Sequence Identity: 20% (19 aa)

PNSDTWCFGCITFFSLTTRIPFLGATPE--------ATIKAILTSHET---------IPDTVSEPGKQFIERCLIKNPLMRLNLNDLYSVSFL
| ||.|  | |... |. . || ... .         ....|. ...          .|| .|. .|.|...|.   |  |.... |......
PASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECIC-KGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase 83396.m00075.AA CAMK-Unique 34-125 15 1.5e-05 14.08 In-house 17-166 (363) Show / Hide 
Range on Protein: 34-125
Range on HMM: 17-166/363
Sequence Identity: 15% (23 aa)

KAVNKNNQNFYAIKSILKTSFQTPEQNA-----------------KFLNEIYILKQVNNKYIASLVDL----IDDSN---------------AYHVVTEL
.. .. .   .|.|.. |   .   | .                 |. .|. |.| |.   |  |.|       |..               ... |.|.
ECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEY

PEGVCLREYIET--------------------NGPLSE--KSVKDIIAKL
 .| .| ..|                      .|..||    .  |...|
CQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCL
Kinase 83396.m00075.AA STE 18-78 17 7.9e-05 13.13 In-house 1-92 (359) Show / Hide 
Range on Protein: 18-78
Range on HMM: 1-92/359
Sequence Identity: 17% (16 aa)

YSFVKELTSGALNGSWKAVNKN---------------NQNFYAIKSILKTSFQT--------------PEQNAKFLNEIYILKQVN--NKYI
. ..... .||     ||.|..               .....||| . . . ..              .|.  ..|.|| |.|. |   ..|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNI
Kinase 83396.m00075.AA MARK 178-267 27 0.00022 10.43 In-house 170-262 (262) Show / Hide 
Range on Protein: 178-267
Range on HMM: 170-262/262
Sequence Identity: 27% (26 aa)

PFLAPEFLSTQKFH-PNSDTWCFGCITFFSLTTRIPFLGAT--PEATIKAILTSHETIPDTVSEPGKQFIERCLIKNPLMRLNLNDLYSVSFL
|. ||| .. ..   |  |.|  | . .| .. . || |.|   .   | ||. . .||. ||   ...| | |  || .|  . .. . ...
PYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 83396.m00075.AA PLK1 18-97 22 0.001493 7.25 In-house 1-80 (253) Show / Hide 
Range on Protein: 18-97
Range on HMM: 1-80/253
Sequence Identity: 22% (18 aa)

YSFVKELTSGALNGSWKAVNKNNQNFYAIKSILKTSFQTPEQNAKFLNEIYILKQVNNKYIASLVDLIDDSNAYHVVTEL
|   . |  |     .   .|. .. .| | . |. .  ..|  |   || | .|.. . |  . .  .|..  ..| ||
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLEL
Kinase 83396.m00075.AA AGC 37-81 15 0.015036 0.81 In-house 26-96 (395) Show / Hide 
Range on Protein: 37-81
Range on HMM: 26-96/395
Sequence Identity: 15% (11 aa)

NKNNQNFYAIKSILKTS--------FQTPEQNAK-------FLNEIYILKQVN----------NKYIAS-L
.| .. .||.| . |           .   ...        . .|  ||...|          . .| . |
KKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKIL