Gene TVAG_463460 (T.vaginalis)

TVAG_463460

Species: T.vaginalis
Alias: TvagK1073, TVAG_463460
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
TVAG_463460.AA Protein None 336 None Fasta, JSON
TVAG_463460.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of TVAG_463460.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase TVAG_463460.AA S_TKc 13-256 17 1.6e-10 -22.59 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-256
Range on HMM: 1-231/231
Sequence Identity: 17% (49 aa)

YTFIGSITTGILAGCWKAFNKKSQETFCIRSIPKAAISAADQYSKFSNQLTLLKQLDNKYIATFIELIEDAKTYHIVTELPEG--MSLHDYITKNGP---
|...  |  |  . ..|. .||... . |  |.           .. . . .||. . ..| .... ..| . ...|.|. .|   .|.||| |.|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---MPEKLVIEMIARLFYIIHYIMHYIPLNY-----DNVYIDGTGH-------LTRYIYPVDDFLSDQNNLGRLSFNPPEMISSKKPHINT-MS--WLMA
   .||  .  ... ..  . | .|     .     .|. .|   |       | | .             | . . .||..     . ..  .  |   
RFPFPE-HARFYMYQICCALEY-CHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCG

SVAYYAMNSKLPFSGSSEEEMTKSILSSRIEIPTSISPEAQIFFEKGFVKNPLMRSSVVDLFV-------TDFL
 . |  .  . ||.   ...| | |.          ||||  | .| ..|.|  | .. ...          ..
CILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase TVAG_463460.AA Pkinase 13-117 19 4.8e-10 36.6 Pfam 1-114 (293) Show / Hide 
Range on Protein: 13-117
Range on HMM: 1-114/293
Sequence Identity: 19% (22 aa)

YTFIGSITTGILAGCWKAFNKKSQETFCIRSIPKAAISAADQYSKFS-NQLTLLKQLDNKYIATFIELIEDAKTYHIVTELPEGM----SLHDYIT--KN
|.... |  |  . ..|. .|........  |.|  ..   .....  . . ..| |. ..| ....  || . ...|.|. ||     .|.|||.  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPM--PEKLVIEMI
|..  .|. .. ..
GCFYFSEWECKFYM
Kinase TVAG_463460.AA Ciliate-E2 13-127 15 2.4e-09 28.25 In-house 1-176 (365) Show / Hide 
Range on Protein: 13-127
Range on HMM: 1-176/365
Sequence Identity: 15% (28 aa)

YTFIGSITTGILA-----GCWKAFN------------------KKSQETFCIRSIPKAAISAADQYSKFSNQLT----------LLKQLDNKYIATFIEL
| ||  | .|  .       ||  .                  |  .  . . .. |  | .  |  .  ...           .|.||....|  ..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IE--DAKTYHIVTELPEGMSLHDYITKN-----------GPMPEKLVIEMIARLFY---------------IIHYI
 .  | ... .|.|. .|..| ||| .|           ... || ...... ...                ..|.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYL
Kinase TVAG_463460.AA CAMKL 64-111 28 4.5e-08 21.69 In-house 65-127 (297) Show / Hide 
Range on Protein: 64-111
Range on HMM: 65-127/297
Sequence Identity: 28% (18 aa)

LLKQLD---NKYIATFIELIEDAKT------YHIVTELPEGMS--LHDYITKN----GPMPEK
..|.|.    . |  . | ||. ..      ...|.|. .| .  |.||| |.    |.|||.
IMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEH
Kinase TVAG_463460.AA CAMK 29-117 11 1e-06 16.8 In-house 12-185 (425) Show / Hide 
Range on Protein: 29-117
Range on HMM: 12-185/425
Sequence Identity: 11% (20 aa)

KAFNKKSQ------------ETFCIRSIPKAAIS-------------------------AADQYSKFSNQLTLLKQ-------LDNKYIATFIELIEDAK
....|...            . . |  |.|  ..                          .    .. . . ..|.       || . |  ..| .||..
LCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNIIKLYEVYEDPH

T-------------------YHIVT---ELPEGM----SLHDYITKNGP---------------MPEKLVIEMI
                    ...|.   |. .|      | |||...|.               ..|. .  ..
YFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYF
Kinase TVAG_463460.AA ULK 29-121 21 2e-06 18.6 In-house 17-135 (329) Show / Hide 
Range on Protein: 29-121
Range on HMM: 17-135/329
Sequence Identity: 21% (25 aa)

KAFNKKS----QETFCIRSIPKAAISAADQYSK-------FSNQLTLLKQLD--------NKYIATFIELIEDA--KTYHIVTELPEGMSLHDYITKNGP
|..|||.    .| . .  |.|  ..   . .        . |   ..|.|.        ...|  ...  |..  . . |..|. .|  | .|| ||..
KGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKK

MPEKL-----VIEMIARLF
.||.        |..|. |
LPEDTEEKKRLSEQEAIQF
Kinase TVAG_463460.AA Ciliate-E2a 64-127 28 2e-06 15.06 In-house 52-118 (275) Show / Hide 
Range on Protein: 64-127
Range on HMM: 52-118/275
Sequence Identity: 28% (19 aa)

LLKQLDNKYIATFIELIEDAKTYHIVTELPEGMSLHDYITKNGPMPEK--LVIEMIARLFY-IIHYI
...|||.. |  ..|  || ..| .|.|. || .| |.| ... . |.   . ...  |..  .||.
IMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYM
Kinase TVAG_463460.AA ASK 220-256 37 3e-06 16.45 In-house 218-254 (254) Show / Hide 
Range on Protein: 220-256
Range on HMM: 218-254/254
Sequence Identity: 37% (14 aa)

EIPTSISPEAQIFFEKGFVKNPLMRSSVVDLFVTDFL
|||...| |.. |  . |  .|  |.|  ||   .||
EIPEELSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase TVAG_463460.AA PLK1 13-98 26 4e-06 15.76 In-house 1-86 (253) Show / Hide 
Range on Protein: 13-98
Range on HMM: 1-86/253
Sequence Identity: 26% (23 aa)

YTFIGSITTGILAGCWKAFNKKSQETFCIRSIPKAAISAADQYSKFSNQLTLLKQLDNKYIATFIELIEDAKTYHIVTELPEGMSL
|.    .  |  | |.   .|. .| |  . .||. .    |  | .  ... .||. . |  | .  || .  .|| || .  ||
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSL
Kinase TVAG_463460.AA MARK 64-112 25 5.6e-05 12.41 In-house 52-105 (262) Show / Hide 
Range on Protein: 64-112
Range on HMM: 52-105/262
Sequence Identity: 25% (14 aa)

LLKQLDNKYIATFIELIE--DAKT-YHIVTELPEGMSLHDYITKN--GPMPEKL
..|.|| ..|  . . ||  . ..  ... |. .| .|.||| .   |...|..
IMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRLHEEE
Kinase TVAG_463460.AA Ciliate-E2-Unclassified 191-256 18 9.1e-05 12.49 In-house 259-352 (352) Show / Hide 
Range on Protein: 191-256
Range on HMM: 259-352/352
Sequence Identity: 18% (17 aa)

VAYYAMNSKLPFSGSSEEE----------------MTKSILSSRIEIPT--------SISPEAQIFFE----KGFVKNPLMRSSVVDLFVTDFL
..|. .  ..||.. ..|.                . . |.   |..|          .||||. | .    | ..|||  | .  ...   ..
ILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase TVAG_463460.AA STE 221-256 28 9.5e-05 12.84 In-house 322-359 (359) Show / Hide 
Range on Protein: 221-256
Range on HMM: 322-359/359
Sequence Identity: 28% (11 aa)

IPTSISPEAQIFFEKGFVKNPLMRSSVVDLFV--TDFL
.|.. ||| . | .| ..|.|  | .. .|      |.
YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase TVAG_463460.AA Ciliate-E2-Unclassified 13-118 15 0.000143 11.8 In-house 1-150 (352) Show / Hide 
Range on Protein: 13-118
Range on HMM: 1-150/352
Sequence Identity: 15% (23 aa)

YTFIGSITTGILAGCWKAFNKKSQETFCIRSIPKAAISAADQYSKF----------SNQLT-------------LLKQLDNKYIATFIELIEDAKTYHIV
|..|  | .|  .  .|. .|| .  . .  . | ... .... ..           |..              .|..... .|  ...  .| ..  ||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TELPEGMSLHDYITKNGP-----------------MPEKLVI-----EMIA
.|. || .|..||.|..                   .|. ..      ..|
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFA
Kinase TVAG_463460.AA MARK 199-256 23 0.000146 11.02 In-house 203-262 (262) Show / Hide 
Range on Protein: 199-256
Range on HMM: 203-262/262
Sequence Identity: 23% (14 aa)

KLPFSGSS--EEEMTKSILSSRIEIPTSISPEAQIFFEKGFVKNPLMRSSVVDLFVTDFL
..|| |..  ..|. | ||. . .||. .|.|.. .  . .. || .| .. ..    ..
YFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase TVAG_463460.AA STE 13-117 12 0.003576 7.2 In-house 1-157 (359) Show / Hide 
Range on Protein: 13-117
Range on HMM: 1-157/359
Sequence Identity: 12% (20 aa)

YTFIGSITTGILAGCWKAFNK------KSQET---------FCIRSIPKAAISA--------------ADQYSKFSNQLTLLKQLD--NKYIATFIELIE
...|. |  |      || |.      |..|.         . |  ...   ..               ..  .. . . ..|...   ..| ...   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DA-------KTYHIVTELPEGMSLHDYITKN--------------GPMPEKLVIEMI
.         . .|. |. .| || | | ..              ...||.... ..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYIC
Kinase TVAG_463460.AA PLK1 186-256 21 0.007238 4.96 In-house 183-253 (253) Show / Hide 
Range on Protein: 186-256
Range on HMM: 183-253/253
Sequence Identity: 21% (15 aa)

WLMASVAYYAMNSKLPFSGSSEEEMTKSILSSRIEIPTSISPEAQIFFEKGFVKNPLMRSSVVDLFVTDFL
| .  . |  .  . ||  .. .|  . |      ||..||. |. . .|   ..|  |  .  .   .|.
WSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase TVAG_463460.AA Pkinase 191-256 11 0.017644 9.85 Pfam 201-293 (293) Show / Hide 
Range on Protein: 191-256
Range on HMM: 201-293/293
Sequence Identity: 11% (11 aa)

VAYYAMNSKLPFSGS------SEEEMTKSILSSRIEIPTSIS---------------------PEAQIFFEKGFVKNPLMRSSVVDLFVTDFL
. |. .. ..||.|.      .. .| . |.. ... . . .                     .|.. | .. . |.|  | .  ...  ...
ILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF