Gene 93444.m00137 (T.vaginalis)

93444.m00137

Species: T.vaginalis
Alias: 93444.m00137, TvagK0107
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
93444.m00137.AA Protein None 438 None Fasta, JSON
93444.m00137.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 93444.m00137.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93444.m00137.AA CAMKL 12-265 36 4.4e-103 329.81 In-house 1-297 (297) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-297/297
Sequence Identity: 36% (110 aa)

YTFLGSLGQGSFATVFRARH-NPTGKFVAVKQFPKAKLQ-DPDDRAAFIN-----------EINIHKIAD---HPLIATCYEVVENSDS------YFLSM
|...  ||.|||..|  |.|   ||. ||.|   | |.. ||  .. ...           ||.|.|  .   || |   |||.|...       ..| |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EIVENDS--LLNFI--NIHNG--LTEIVARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNG--NIRLIDFGLSKKIHA----TNAMMNTICGSPAY
| ... .  |...|  . | .  ..|  ||..|.|||  ..|.|.   ..|||.|.|||||| ||  || .||||.| ..      .. ...| ||||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

AAPELVQG--IPYT-KSVDIWSIGVILFAMVAGYLPFDDDNI-------HAQLHRIVTREPEYPD---TLSPILVDLLKRLLCKDPSLRITINELKIHPW
.|||..||   ||  . |||||.||||.||| ||||||||..       .  |.... .  .||.    .|  . ||....| ..|. |.|| ... |||
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPW

V
.
M
Kinase 93444.m00137.AA AGC 12-265 23 7.1e-101 260.94 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-395/395
Sequence Identity: 23% (93 aa)

YTFLGSLGQGSFATVFRARHN------PTGKFVAVKQFPKAK-LQDPD--DRAAFINE------------INIHKIAD----------HPLIAT-CYEVV
. ||  .|.||| .|. .|..       |||. |.|   |..  .. .  . .  ..|             || . ..          || |    .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ENSDS--YFLSMEIVE---------ND-SLLNFIN---IHNGLTEIVARKIFCQ-------IVMVLDYLHNTLNVIHRD-LKAENILLDLNGNIRLIDFG
.. |    .. || ..          .  |.  .        ..| .|| ....       ||. |.|||. ...|||| || |||||| .|.|.| |||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKK---------------------------------------------------IHATNAMMNTICG--SPAYAAPELVQGIPYTKSVDIWS--IGVIL
|.|.                                                   .   ... .|.||  .| | ||| .    |.|..|.||   |...
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

FAMVAGYLPFDDDN----------IHAQLHRIV------TREPEYP----------DTLSPILVDLLKRLLCKDPSLRIT----------INELKIHPWV
. |..|| || .||           .   ..|       . ....|          . .|| ..||.|.||||||. |..          ..|.| ||| 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 93444.m00137.AA CAMK 17-265 23 1.8e-100 324.49 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-265
Range on HMM: 1-425/425
Sequence Identity: 23% (102 aa)

SLGQGSFATVFRARHNPTG------------KFVAVKQFPKAKLQD-------------------------PDDRAAFINEINIHKI-------ADHPLI
 ||.|||..|....|  |.            . ||.|  .| ||.|                         | ||. . .||.|.|         ||| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ATCYEVVE------------NSDS--------YFLSM---EIVEND----SLLNFINIHNG---------------LTEIVARKIFCQIVMVLDYLHNTL
  .||| |            . .         ... |   | ...      |...|  | .               .||  ||..| ||.  ..|.|.  
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

NVIHRDLKAENILLDLN-----------------GNIRLIDFGLSKKIHA-----------------------TNAMMNTICGSPAYAA-PELVQG----
 ..||||| |||||| |                 .|| .||||...|.                         .. .|.| ||.|.|.| ||...|    
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------IPYTKSVDIWSIGVILFAMVAGYLPFDDD-------------NIHAQLHRIVTREPEYPDT------------------------LSPIL
           .|....|.||.||||..|. ||.||..|             |..  ...| . . ..|.                         .|.  
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

VDLLKRLLCKDPSLRITINELKIHPWV
 ||....|..||. |.|| . . |||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 93444.m00137.AA S_TKc 12-265 32 8e-94 318.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

YTFLGSLGQGSFATVFRARHNPTGKFVAVKQFPKAKLQDPDDRAAFINEINIHKIADHPLIATCYEVVENSDSYFLSMEIVEN--DSLLNFINIHNG---
|..|  .|.|.|..|...||. ||. ||.|. .            ...||.|.|  .|| | ..|.| .. |.... || ...   .|. .|  ...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTEIVARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNGNIRLIDFGLSKKIHATNAMMNTICGSPAYAAPELVQGIPYTK-SVDIWSIGVILF
   ..| .||....||.  |.|.|.  ..|||||| ||||||   .| ..||||....       .|.||.| | |||..   .|.| ..|.||.|.||.
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

AMVAGYLPFDDDNIHAQLHRIVTREPEYPDTLSPILVDLLKRLLCKDPSLRITINELKI-------HPWV
 |..|| ||.  .... ...|.          || . |.....|.|||. |.|. |.         |||.
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93444.m00137.AA AMPK 12-265 42 8.3e-91 269.82 In-house 1-254 (254) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-254/254
Sequence Identity: 42% (109 aa)

YTFLGSLGQGSFATVFRARHNPTGKFVAVKQFPKAKLQDPDDRAAFINEINIHKIADHPLIATCYEVV-ENSDSYFLSMEIVENDSLLNFINIHNGLTEI
|     .| |.|  |  . |  ||. ||.|   | |..| |.     .|| | |.  || |   |||. |  .  |. || | .  |  .|  |. |.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

VARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNGNIRLIDFGLSKKIHATNAMMNTICGSPAYAAPELVQGIPYT-KSVDIWSIGVILFAMVAGYL
 |.. | ||.  ..|.|. ... ||||| ||.||| | || . ||||| ..   . .  | |||| |||||...| .|    ||||| ||||.||. |||
EACRFFQQIISGVEYCHR-HMIVHRDLKPENLLLDHNKNIKIVDFGLS-NMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYL

PFDDDNIHAQLHRIVTREPEYPDTLSPILVDLLKRLLCKDPSLRITINELKIHPWV
||||.|. .   .|.  |.. |. |||   ||.|..|..||  ||||.... ||| 
PFDDENTPTLYKKIKNGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 93444.m00137.AA Pkinase 12-265 31 2.1e-87 301.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

YTFLGSLGQGSFATVFRARHNPTGKFVAVKQFPKAKLQDPDDRAAFI-NEINIHKIADHPLIATCYEVVENSDSYFLSMEIVEND----SLLNFIN--IH
|.... .|.|||..|....|  ||| ||||...| .  .  |....  .|| |.|  .|| | ..|...|..|.. . || .|..    .|  .|    |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NGL--TEIVARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNGNI----RLIDFGLSKKI-HATNAMMNTICGSPAYAAPELVQ-GIPYTKSVDIWS
...  .| ...... ||.  |.|.|.  ..|||||| ||||.| ||.|    ...||||.|.. .  |  |.|.||.| |.|||... | .|...||.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGVILFAMVAGYLPFDDD------NIHAQLHRIVTREPEYPDTLS---------------------PILVDLLKRLLCKDPSLRITINELKIHPWV
.|.||. |. |..||...      .  . . ||  ......   .                     . . |..|..|||||. |.|. ... |||.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93444.m00137.AA MARK 12-265 40 2.1e-87 285.73 In-house 1-262 (262) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-262/262
Sequence Identity: 40% (107 aa)

YTFLGSLGQGSFATVFRARHNPTGKFVAVKQFPKAKLQDPDDRAAFINEINIHKIADHPLIATCYEVVE--NSDS-YFLSMEIVENDSLLNFINIH--NG
| .|  .|.||.|.|  |.| .||. ||.|  .| ||.||  .  .  ||.|.|  ||| |  ...|.|  ..    .| || ... .|...|  |    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LTEIVARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNG--NIRLIDFGLSKKIHATNAMMNTICGSPAYAAPELVQGIPYT-KSVDIWSIGVILFA
|.|  ||.|| |||  . |.|.   ..|||.|.||||.| ||  || .||||.| .|  .. . || ||.|.|.|||.... ||. . ||||| ||.|..
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICI-PPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYF

MVAGYLPFDDDN--IHAQLHRIVTREPEYPDTLSPILVDLLKRLLCKDPSLRITINELKIHPWV
|| ||.|||.|.  .     .|.. ....|. .|. . .|..|||  .|. |.|| |.  |||.
MVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 93444.m00137.AA Ciliate-E2 12-265 24 1.7e-74 253.81 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

YTFLGSLGQGSFATVFRARHNPTGKFVA-----------------VKQFPKAKLQDPDDRAAFINEINIHK----------------IADHPLIATCYEV
| |.  .|||.|..|.....  ..| .|                  ...   | . ...  .. .||.| .                . .|| |  .||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VE--NSDSYFLSMEIVENDSLLNFINIH-----------NGLTEIVARKIFCQIV---------------MVLDYLHNTLNVIHRDLKAENILLDLNGNI
 .  . ....| || ..  .|. .|...           . .||  ...|. ||.                 | |||.  |.||||.| ||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

RLIDFGLSKKIHATNA-------------------------------MMNTICGSPAYAAPELVQGIP---------YTKSVDIWSIGVILFAMVAGYLP
 .||||||||..  |                                | |||||.| | ||| ..| .         |....||||.||||. |. |..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FDDDNIHAQLHRIVTREPEYP------------------DTLSPILVDLLKR----LLCKDPSLRIT-INELKIHPWV
|        .  |   . ..|                  . .|.   ||.|.    .|.|||. ||| ..... ||| 
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 93444.m00137.AA Ciliate-E2-Unclassified 12-265 27 8e-73 248.25 In-house 1-352 (352) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

YTFLGSLGQGSFATVFRARHNPTGKFV-----AVKQFPKAKLQDPDDRAAFINE---INIHK---------IAD-------HPLIATCYEVVENSDSYFL
|...  .|||.|..|....|. .. ..     . |.  ....|       ..||   .|..|         |..       ||.|  .... .. .  ..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

SMEIVENDSLLNFINIHNG-----------------LTEIVAR-----KIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNG---NIRLIDFGLSKKIH
 || .|. .|...|.. ..                 .||  |.     ..| ||.  |.|||  .|.||||.| ||||.| ||   .|..||||.|||. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

AT---------------NAMMNTICGSPAYA----APELVQGIPYT----KSVDIWSIGVILFAMVAGYLPFDDDNIHA---------------QLHRIV
                 . ||.|.||.| |     |||. ||  |     ...|||| ||||..|. ||.||.| |                  ||... 
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

-TREPEYP--------DTLSPILVDLLK----RLLCKDPSLRITINELKIHPWV
  .....|        ...||   |...    ..| |.|. |||..... ||| 
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 93444.m00137.AA AktR 12-265 32 1.3e-71 244.27 In-house 1-268 (268) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-268/268
Sequence Identity: 32% (86 aa)

YTFLGSLGQGSFATVFRARHN-PTGKFVAVKQFPKAKLQDPDDRAAFINEINIHK-IADHPLIATCYEVVENSDSYFLSMEIVENDSLLNFINIHNGLTE
....  ||.| |..|. ....  ..|..| |   | |...   . . |.| || . ...|| |   ..  .. .  |. ||....  |.. ..  . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

IVARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNGNIRLIDFGLSK--KIHATNAMMNTICGSPAYAAPELVQG-IPYTKSVDIWSIGVILFAMVA
 .||..|.||.  |.|||...|.| |||| ||||||..|.....||||||  .. . . . ...||.|.| ||| ..   ...||||.|..|. .. ||.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GYLPFDDDNIHAQLHRIVTRE---PEYPDTLSPILVDLLK-RLLCKDPSLRIT-----INELKIHPWV
|. ||...|    ...| . .   ..||  .|. . ||.. .||||.|  |..     . |.| ||| 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 93444.m00137.AA ULK 12-265 26 3.1e-69 236.31 In-house 1-324 (324) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-324/324
Sequence Identity: 26% (88 aa)

YTFLGSLGQGSFA-TVFRARHNPT---GKFVAVKQFPKAKLQD-PDDRA------AFINEINIHKIAD---HPL--IATCYEVVENSDS--YFLSMEIVE
|     ||.|||. .|...|.. |   ...||.|. .| |... . ..        ..|||.| |. .   ||   |   |.. |.|..  ... ||  .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NDSLLNFINIHNGLTEIV----------ARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNGN------------IRLIDFGLSKKIHATN---AMM
   | ..|. ...|.| .          |...| ||.  . .||.  |.||||.| .|||.  .              . . |||..|..   |    |.
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMC

NTIC------GSPAYAAPELVQ----GIPYT-KSVDIWSIGVILFAMVAGYLP----FDDDNI-HAQLHR--------IVTREPEYPD-----TLSPILV
 |..      |.| | ||...|    ..||. . .||||.|.|.. |. |. |    | |... ...| .        | ..  ..|.      .|| . 
QTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLLKRLLCKDPSLRITINELKIHPWV
||..|.|..|.. ||.. |.  |||.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 93444.m00137.AA ULK 12-265 27 8.3e-69 234.91 In-house 1-329 (329) Show / Hide 
Range on Protein: 12-265
Range on HMM: 1-329/329
Sequence Identity: 27% (90 aa)

YTFLGSLGQGSFATVFRARHNPT----GKFVAVKQFPKAK-LQDPDDRA------AFINEINIHKIAD--------HPLIATCYEVVENSDS--YFLSME
|     ||.|||..|...|.. |    .. ||.|. .| |  |.....        ..||| | |  .        || |   |.. |.|..  ... ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

IVENDSLLNFINIHNGLTEIV----------ARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLN------------GNIRLIDFGLSKKIHAT---N
  .   | ..|. ...|.| .          |...|.||.  . .||   |.||||.| .|||.. .            | . . |||..|..      .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK-HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

AMMNTIC------GSPAYAAPELVQ----GIPYT-KSVDIWSIGVILFAMVAGYLPFDDDNIHAQLHRIVTRE---------------PEYP-----DTL
.|| |        |.| | ||...|    ..||. . .||||.|.|.. |. |. ||    .  | ..|....               ...|     ...
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQI

SPILVDLLKRLLCKDPSLRITINELKIHPWV
|| . ||..|.|..|.. ||.. ||  |||.
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 93444.m00137.AA TyrKc 12-269 22 1.9e-14 10.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-269
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YTFLGSLGQGSFATVFRARHNPTGKFVAVKQFPKAKLQDPDDRAAFINEINIHKIA--DHPLIATCYEVVENS-------DSYFLSMEIVENDSLLNFIN
 |..  || | | .|.... .     ||||   . .      |..|..|..| .    .|| |  .| |.  .       . ... || ... .|.... 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

IHNG-LTEIVARKIFCQIVMVLDYLHNTLNVIHRDLKAENILLDLNGNIRLIDFGLSKKIHAT------NAMMNT----ICG--SP-AYAAPELVQGIPY
 | . |.     ..  ||    .|||   |.||||| | |.|.. |. ..  |||||..|.          .  .     .    |    |||  .   .
KHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TKSVDIWSIGVILFAMVA-GYLPFDDD----NIHAQLHRIVTRE--PEYPDT--------LSPILVDLLKRLLCKDPSLRITINELKIHPWVHQSI
|   |.|| || .. .   |  |  ..       ..... | .   .. |.          .. . .. |.    ||. | | .|.      |. .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase 93444.m00137.AA Pkinase_Tyr 12-63 29 5e-05 17.64 Pfam 1-56 (270) Show / Hide 
Range on Protein: 12-63
Range on HMM: 1-56/270
Sequence Identity: 29% (17 aa)

YTFLGSLGQGSFATVFRARHN----PTGKFVAVKQFPKAKLQDPD-DRAAFINEINI
 ||.  ||.|.| .|.... .     |.  ||||   | .  ...  |..|..|..|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKI
Kinase 93444.m00137.AA Pkinase_Tyr 131-161 48 0.011054 9.71 Pfam 131-161 (270) Show / Hide 
Range on Protein: 131-161
Range on HMM: 131-161/270
Sequence Identity: 48% (15 aa)

NVIHRDLKAENILLDLNGNIRLIDFGLSKKI
| ||||| | |.|.. |. ..  ||||.. |
NCIHRDLAARNCLVTENNVVKICDFGLARDI