Gene 94095.m00106 (T.vaginalis)

94095.m00106

Species: T.vaginalis
Alias: TvagK0334, 94095.m00106
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94095.m00106.AA Protein None 904 None Fasta, JSON
94095.m00106.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 94095.m00106.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94095.m00106.AA TKL 32-276 25 2.5e-81 276.49 In-house 1-364 (364) Show / Hide 
Range on Protein: 32-276
Range on HMM: 1-364/364
Sequence Identity: 25% (96 aa)

IGKGGYAEVWLVSYKGTE--------KQMALKQLFSD--------------------------ISSKQVHHFAREIATMAKANHPYFVKFMG------F-
||.||..||.   ..|.         | .| |.. |.                           .|.   .. .||  | . .||  |.|||      . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-SPYRP------MSLLTEYMPNGS-LYRFIRQDPKGKILNGTRRTIIAMGIASAMATLHSMS--------IIHRDLKSMNILLDSEFY------------
   ..|      . . .||.|.|| |....            .|  .|..||..|. ||||         |||||||| |||.|. .             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PRICDFGIARFNQNDE--------------------KLTMRLGTPHWMAPESLYGE----------------GYGFPVDVYSFAMVLYELLTFKLPWA
  . |||||..||.....                    .. .. ||| ||||| | |.                 |   .|||||..||.|.|| ..|..
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

GMDALAVT---------RAVVIEKKRPILP-------------KCPAPLKNLICRCWDQDPNQRPTFAEIYRLF
...   .            |. ...|| .|              || ..|.|. .|||.||..||.| ||   .
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase 94095.m00106.AA Pkinase 26-276 27 1.2e-70 245.79 Pfam 1-293 (293) Show / Hide 
Range on Protein: 26-276
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

YVKIKTIGKGGYAEVWLVSYKGTEKQMALKQLF-SDISSKQVHHFAR--EIATMAKANHPYFVKFMGFS-PYRPMSLLTEYMPNG----SLYRFIRQDPK
|.....||.|....|..   |||.|. |.|..  ....|..  . .|  ||. |.. |||. |.. ..    . . . .||...|    .|...|. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKILNGTRRTIIAM--GIASAMATLHSMSIIHRDLKSMNILLDSEFYP----RICDFGIARF--NQNDEKLTMRLGTPHWMAPESLY-GEGYGFPVDVYS
|... .. .... .   |..... .|||.|||||||. |||.|.. ..    .|||||.|..  . |.. .| . |||..|||| .  |..|| .||..|
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FAMVLYELLTFKLPWAGM------DALAVTRAVVI-EKKRPILPKCP-------------------APLKNLICRCWDQDPNQRPTFAEIYRL--F
.  .|||.|. ..|. |       | ... . .   . ....  .|.                    ..| .|..|...||..|||...|     |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 94095.m00106.AA MLK 29-276 29 7.3e-70 238.42 In-house 4-291 (291) Show / Hide 
Range on Protein: 29-276
Range on HMM: 4-291/291
Sequence Identity: 29% (85 aa)

IKTIGKGGYAEVWLVSYKGTE---KQMALKQLFSDI-----S---SKQVHHFAREIATMAKAN-HPYFVKFMGFSPYRPMS--LLTEYMPNGSLYRFIRQ
 . ||.|.. .||.  .....   |  |.|. ...|     .   ....  ..|. . . . | ||....|.| .   |    ...||...||||.... 
HEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHG

-DPKGK----------ILNGTRRTIIAMGIASAMATLHSMS---IIHRDLKSMNILLDS------EFYPRICDFGIARFNQNDEK-LTMRLGTPHWMAPE
 ..|.           .        .|. .|..|. ||||    |||||||| |||.|       .   .|||||..|. .. ..  . . ||. |||||
ARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPE

SL---YGEGYGFPVDVYSFAMVLYELLTFKLPWA-GMDALAVTRAVVIEKKR-PILPKCPAPLKNLICRCWDQDPNQRPTFAEIYRLF
 .    .| |   .||.|...||.|.|| ..| . ..|..|.   |. ...| || . ||...|.|. .||.|||..||.|..|   .
VIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 94095.m00106.AA TKL-Unique 28-276 34 9.8e-68 231.34 In-house 1-290 (290) Show / Hide 
Range on Protein: 28-276
Range on HMM: 1-290/290
Sequence Identity: 34% (100 aa)

KIKTIGKGGYAEVWLVSYKGTEKQMALKQLF--SDISSKQVHHFAREIATMAKAN-HPYFVKFMGFSP----YRP-MSLLTEYMPNGSLYRFIRQ-----
 ...|| |||..|  . ..|...  |.||..  .|.|.. .  | .|. .| | . ||  |..||..     | | |.. .||.| ||||  . |     
FWNKIGEGGYGQVYKGKWRGYPV--AIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

--DPKGKILNGTRRTIIAMGIASAMATLHSMS--IIHRDLKSMNILLDSE-----FYPRICDFGIARFNQ--NDEKLTMR--------LGTPHWMAPESL
   .. . ||  .|  .|  ||..| .||. .  |||||||| |.|.|..     .  .|||||...||   |......         .|.. ||||| |
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

YG--EGYGFPVDVYSFAMVLYELLTFKL------PWAGMDALAVTRAVVI--EKKRPIL-PKCPAPLKNLICRCWDQDPNQRPTFAEIYRLF
 .  . |   .|||||..||.|..| |.      |  |||  ..  .|    |..|| . . ||  ...|| .||..|| |||.| ||.   
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
S_TKc 94095.m00106.AA S_TKc 26-278 28 4.7e-63 216.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 26-278
Range on HMM: 1-231/231
Sequence Identity: 28% (76 aa)

YVKIKTIGKGGYAEVWLVSYKGTEKQMALKQLFSDISSKQVHHFAREIATMAKANHPYFVKFMGFSPYRPMSLLTEYMPN--GSLYRFIRQDPKGK----
| ....||||....|...  |.| ...|.|..          |. |||. . | .||. ||. ..     . . .||...  |.|...|.. ....    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

ILNGTRRTIIAMGIASAMATLHSMSIIHRDLKSMNILLDSEFYPRICDFGIARFNQNDEKLTMRLGTPHWMAPESLYGEGYGF-PVDVYSFAMVLYELLT
.   . | ...  |..|.. .||. |||||||  |||||.     |||||.||.       |   |||..|||| |   |||. ..|..|.  .|||.|.
FPE-HARFYMYQ-ICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

FKLPWAGMDALAVTRAVVIEKKRPILPKCPAPLKNLICRCWDQDPNQRPTFAEIYR-------LFAT
 . |.   .  .. . ..           . ..|..|..|.. ||..|||  |. .           
GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94095.m00106.AA Dicty4 26-272 35 1.6e-57 190.51 In-house 1-269 (277) Show / Hide 
Range on Protein: 26-272
Range on HMM: 1-269/277
Sequence Identity: 35% (95 aa)

YVKIKTIGKGGYAEVWLVSYKGTEKQMALKQL---FSDISSKQVHHFAREIATMAKANHPYFVKFMGFSP---YRP--MSLLTEYMPNGSLYRFIRQ---
... . ||||...|| . . .|  |. | | |     . ...    |..|.. |.|  ||  ..||| .      |  |.  ||||| |.||. ..    
INIEQRIGKGSFGEVYKGTWRG--KEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

-DPKGKILNGTRRTI---IAMGIASAMATLHS--MSIIHRDLKSMNILLDSEFYPRICDFGIARFNQNDEKLTM----RLGTPHWMAPESLYGEGYGFPV
   . . |  ....    .|  .|  |. ||.    |||||||| |.| |  .   .||||...  . .| ..       ||| ||||| . ...|   .
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFAMVLYELLTFKLPWA--GMDALAVTRAVVIEKKRPILPK-CPAPLKNLICRCWDQDPNQRPTFAEI
|||||..||.|.|| . | .  .|.   . |||. .| ||..|. ||...| || .||| ||..||.|.||
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEI
Kinase 94095.m00106.AA Dicty5 69-280 39 5.9e-53 180.61 In-house 43-260 (260) Show / Hide 
Range on Protein: 69-280
Range on HMM: 43-260/260
Sequence Identity: 39% (86 aa)

FAREIATMAKAN--HPYFVKFMGFSPYRPMS--LLTEYMPNGSLYRFIRQDPK--GKILNGTRRTIIAMGIASAMATLHSMSIIHRDLKSMNILLDSEFY
| ||.. |      || |... |   |       .|||  ||||    ..  |  |. .    .  .|..|| .|  ||||.||||||||||.|.  .. 
FYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWK

PRICDFGIARFNQNDEKLTMRLGTPHWMAPESLYGEGYGFPVDVYSFAMVLYELLTFKLPWAGMDALAVTRAVVIEK-KRPILPK-CPAPLKNLICRCWD
  | |||. ||  |  . || .||. |||.|   | .|  ..|||||. ||.|..| | |   .       .| . |  || .|| ||    |||  || 
IKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNI--PVMVMKGERPTIPKDCPTEISNLIKKCWQ

QDPNQRPTFAEIYRLFATGK
| | .||.| ||   |    
QKPHNRPSFKEICKYFESII
Kinase 94095.m00106.AA Dicty4-Unclassified 27-276 34 1.1e-52 178.69 In-house 1-263 (263) Show / Hide 
Range on Protein: 27-276
Range on HMM: 1-263/263
Sequence Identity: 34% (91 aa)

VKI-KTIGKGGYAEVWLVSYKGTEKQMALKQLFSDISSKQ---VHHFAREIATMAKANHPYFVKFMGFSPYRP------MSLLTEYMPNGSLYRFIR---
..| . ||||  ..|     ||  |  | | . .   .     .  | .|.. .    ||  ||  | .   |      |   .| |. | |   |    
IQIDQFIGKGHFSKVHKGNWKG--KDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSKP

-QDPKGKILNGTRRTIIAMGIASAMATLHSMSIIHRDLKSMNILLDSEFYPRICDFGIARFNQNDEKLTMRLGTPHWMAPESLYGEGYGFPVDVYSFAMV
    .   |. |    .|. ||  |. ||.  .||||.|| |||.|  |  .| ||||.|   .   .|   ||| | .|| | .| |    ||||.||.
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LYELLTFKLPWAGMD-ALAVTRAVVIEKKRPILPK-CPAPLKNLICRCWDQDPNQRPTFAEIYRLF
||||.|   |. .    . . | |   | || .|  |.  .| ||  ||  ||| |||. .|    
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 94095.m00106.AA DRK 27-278 35 3.3e-51 171.68 In-house 1-258 (258) Show / Hide 
Range on Protein: 27-278
Range on HMM: 1-258/258
Sequence Identity: 35% (95 aa)

VKIKT-IGKGGYAEVWLVSYKGTEKQMALKQLFSD-IS-SKQVHHFAREIATMAKANHPYFVKFMGFSPYRPMSLL--TEYMPNGSLYRFIRQDPKGKIL
.||   ||.|.|.||.. .  ||  | | | || . |   . .  |.|||  | .  ||  . ||| .   | . .  .|||| ||||. |  |.. . .
IKIGNRIGRGNYGEVFRGTWRGT--QVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMG-TCNNPPDICICMEYMPRGSLYN-ILHDESIE-M

NGTRRTIIAMGIASAMATLHSMS--IIHRDLKSMNILLDSEFYPRICDFGIAR----FNQNDEKLTMRLGTPHWMAPESLYGEGYGFPVDVYSFAMVLYE
   ..  ... .|  |  ||.    |||||||| | | |  .   . ||| .       |     ||  ||| | ||| |  ..|    |||||| || |
DWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVLRNQRYTEKADVYSFAIVLWE

LLTFKLPWAGMDALAVTRAVVIEKKRPILPK-CPAPLKNLICRCWDQDPNQRPTFAEIYRLFAT
..| . | .||  . | ..|  .. ||. |. ||..   |. .||. || .||.. |.      
CVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 94095.m00106.AA Pkinase_Tyr 26-276 29 4.6e-51 173.55 Pfam 1-270 (270) Show / Hide 
Range on Protein: 26-276
Range on HMM: 1-270/270
Sequence Identity: 29% (80 aa)

YVKIKTIGKGGYAEVWLVSYK----GTEKQMALKQLFSDISSKQ---VHHFAREIATMAKA-NHPYFVKFMGFSP--YRP--MSLLTEYMPNGSLYRFIR
 ...|..|.| . ||..  .|    .|. . | | |  . ....      | ||...| .  .||  |...|      .|  . . .||||.|.|. . |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

QD-PKGKILNGTRRTIIAMGIASAMATLHSMSIIHRDLKSMNILLDSEFYPRICDFGIARFNQNDEKL-TMRLGTP---HWMAPESLYGEGYGFPVDVYS
.  . .. |.  .   ... ||..|. |.|. .|||||   |.|.....  .||||| ||  .||.   ..| |..    |||||..    .    ||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FAMVLYELLTF-KLP-WAGMDALAVTRAVVIEKKRPILPK-CPAPLKNLICRCWDQDPNQRPTFAEIYRLF
|  ...|..|. . | ..||.   | ...  .  |   |. ||... .|...||..||..||||.||.. .
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 94095.m00106.AA LRRK 26-278 25 6.9e-51 175.37 In-house 1-351 (351) Show / Hide 
Range on Protein: 26-278
Range on HMM: 1-351/351
Sequence Identity: 25% (92 aa)

YVKIKTIGKGGYA-EVWLVSYKGTEKQ------------------------------MALKQLFSD---------------------------------I
 .. . ||.||.. .|    |... ..                               | |..  |                                  
LKIEEQIGRGGFGTFV----YRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHED

SSKQVHHFAREIATMAKANHPYFVKFMGFSPYRPMSLLTEYMPNGSLYRFIRQDPKGKI----LNGTRRTI--IAMGIASAMATLHSMS--IIHRDLKSM
...  . | .|.. | . |||. |. .||.  .|. . .||.|.|.||.|..   . ..     . .. ..  ||. ||..|. ||| .  |||||||| 
CCRAFREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSP

NILL---D---------SEFYPRICDFGIAR-FNQNDEK-LTMR-LGTPHWMAPESLYGE---GYGFPVDVYSFAMVLYELLTFK-LPWAGMDALA----
||||   .          .    |.|||| | | | . . .... .|.| ||||| . ..    |  .||.|||.|.|.|||| . .|  ..|  .    
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQW

--VTRAVVIEKKRPILP-K-CPA-----PLKNLICRCWDQDPNQRPTFAEIYRLFAT
    .  .||. || .|   ||       ...||  ||..||..||.| .|     .
MEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 94095.m00106.AA HH498 69-276 30 1.5e-50 158.26 In-house 49-284 (284) Show / Hide 
Range on Protein: 69-276
Range on HMM: 49-284/284
Sequence Identity: 30% (71 aa)

FAREIATMAKANHPYFVKFMGFSPYRPMSLL--TEYMPNGSLYRFI---------------RQDPKGKILNGTRRTIIAMGIASAMATLHS---MSIIHR
| ||.  | . |||. |.|.. .   |  ..  |.|  ||||..                  |     |.    . .|.. .|  |  ||.     ||||
FCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHR

DLKSMNILLDSEFYPRICDFGIARFNQ--NDEKLTMRLGTPHWMAPESLY-GEGYGFPVDVYSFAMVLYELLTFKLPWAGMDALAVTRAVVIEKKRPILP
|| | |||.. .    . |||. || .   |. .|   | . |||||    .  |   |||.|.||...|..| ..| .     |    .   . || .|
DLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIP

KC-----PAPLKNLICRCWDQDPNQRPTFAEIYRLF
       |..  ||| .||.. |. ||.|..| .. 
QTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 94095.m00106.AA STE 26-271 23 8.2e-46 158.51 In-house 1-350 (359) Show / Hide 
Range on Protein: 26-271
Range on HMM: 1-350/359
Sequence Identity: 23% (83 aa)

YVKIKTIGKGGYAEVWLVSYK------GTEKQ---------MALKQLF----------------SDISSKQVHHFAREIATMAKAN--HPYFVKFMGFSP
. .|. ||||.. .| .  ..       | ..         || ||.                 ... ....  . .|| .| | |  ||. ||. |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YRP--------MSLLTEYMPNGSLYRFIRQD-PKGKILN----------GTRRTIIAMGIASA-MATLHSMSIIHRDLKSMNILLDSEFYPRICDFGIAR
.            .  |||..|||  .|..   .|| ||           .   .|.  |  . .. |||. |||||.|. ||||       .||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FNQN-----------------DEKLTMRLGTPHWMAPESLYG------EGYGFPVDVYSFAMVLYELLTFKLPWAGMDAL----AVTRAVVIE-------
  ..                 ..| .   ||| ||||| . .       ||.. .|..|.  .. |..| | ||. |  .    . ..  ...       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---KKRPILP--------------------KCPAPLKNLICRCWDQDPNQRPTFAE
   .. | ||                    |.  ..|. | .| . |||.|||  .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 94095.m00106.AA TyrKc 26-276 27 2.9e-41 144.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 26-276
Range on HMM: 1-280/280
Sequence Identity: 27% (81 aa)

YVKIKTIGKGGYAEVWLVSYKGTEKQMALKQLFSDISSKQVHHFAREIATMAKA--NHPYFVKFMGFSPY--------RPMSLLTEYMPNGSLYRFIRQD
 ...|..| | . ||..  .|    | | | | .|     .  | ||.  | |   .||  |.. |             |. ...||||.|.|  ..|  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

PKGKILNGTRRTIIAMGIASAMATLHSMSIIHRDLKSMNILLDSEFYPRICDFGIARFNQND-------EKLTMRL--GTP-----HWMAPESLYGEG-Y
 .   |.      ..  ||. |. |||. .|||||   |.|.....  .|.||| .|.  .|       .  ...   |.       |||||..  .| .
RPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKF

GFPVDVYSFAMVLYELLTF-KLPWAG-----MDALAVTRAVVIEKKRPILPK--------CPAPLKNLICRCWDQDPNQRPTFAEIYRLF
 .  ||.||  ...|..|. . |. |     |..  | . |   . .|. |         ||. . ... .||. ||..||||.||...|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF