87912.m00115

Species: T.vaginalis
Alias: 87912.m00115, TvagK0539
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
87912.m00115.AA Protein None 321 None Fasta, JSON
87912.m00115.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 87912.m00115.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 87912.m00115.AA CAMK 27-271 19 6.9e-79 253.68 In-house 1-421 (425) Show / Hide
Range on Protein: 27-271
Range on HMM: 1-421/425
Sequence Identity: 19% (81 aa)

VIGEGASSVVVVVRHSKTK------------DLFACKIISR----------------KNQENYTF---------IYRLETEIRVLER-------IRHPGI
..|.|. ..|  ..| .|.              .|.|||..                .. ..              ... ||... .       ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKIQDILYI-------------------DDLICIIM---EYGRRG----MLYDYVINRGH---------------LPEWEATKILVSLLNTLEYLHSINV
.|. ..                      |. ....|   ||   |     |.||.. .|.               ..|.|| ..   ..  ..|.|| |.
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKLDNIVLTQD-----------------FQPKLVDFGLSYQALSDDDNY----------------------RRTFCGTLEYVA-PESFEH------
.|||||..|| |...                 .. |..|||.. .  ....|.                       .|||||.||.| || ..       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------KNYDGRKADIWSLGICYYSMLTCQYPWKG--------------TDRGIMKAILAGEVE-IPEQ-----------------------LSDRTKE
       | |.|.|.|.||.|.  | ||.  .|. |              .|. ... |..|. . .|..                       .|.  | 
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

VLKLLLTPDPEKRPTAREMLE
 .. .|..|||||.|. . |.
LIRKMLQVDPEKRMTIEQCLN

S_TKc 87912.m00115.AA S_TKc 22-273 33 1.2e-77 265.21 SMART 1-231 (231) Show / Hide
Range on Protein: 22-273
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLFACKIISRKNQENYTFIYRLETEIRVLERIRHPGIVKIQDILYIDDLICIIMEYGRR--GMLYDYVINRGH---
|  . .||.|| ..|  .|| ||. ..|.|||.           ... ||..|.. .|| |||. |. .  | ....|||     | |.||  .||.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LPEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDFQPKLVDFGLSYQALSDDDNYRRTFCGTLEYVAPESFEHKNYDGRKADIWSLGICYY
   .|| .| ...  ... |||.|| .. ||||| .|| |..  . |. ||||. |         .|||||..|.||| .    |...|.|.||.|.. |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

SMLTCQYPWKGTDRGIMKAILAGEVEIPEQLSDRTKEVLKLLLTPDPEKRPTAREMLE---------LM
 ||. . |.  ..  ..| |.          |.  |. .. .|. |||||||| | |.          .
EMLCGYPPFP-QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 87912.m00115.AA AGC 22-268 22 2.4e-73 188.12 In-house 1-378 (395) Show / Hide
Range on Protein: 22-268
Range on HMM: 1-378/395
Sequence Identity: 22% (87 aa)

YVPIHVIGEGASSVVVVVRHS------KTKDLFACKIISRKN--------QENYTFIYR-------LETEIRVLERIR----------HPGIVK-IQDIL
.  . |||.|. . |  ||.        |....|.|... |         .. .| .         .  | ..||...          || |||      
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YIDDL--ICIIMEYGR---------RG-MLYDYVI---NRGHLPEWEATKILVS-------LLNTLEYLHS-INVAHRD-LKLDNIVLTQDFQPKLVDFG
  .|   ....|||            | .|. .     ..|...| .|  ..         ..  ||||||  .. ||| ||..||.|..|   ||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSYQALSDDDN-------------------------------------------------YRRTFCG--TLEYVAPESFEHKNYDGRKADIWS--LGICY
|. .  .|...                                                    ||||  | ||.||| .      |. .|.||  ||.. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YSMLTCQYPWKGTDR-----------GIMKAILAG------EVEIP----------EQLSDRTKEVLKLLLTPDPEKRPTARE
| ||| . |  | ..            ... |. |      .|..|          ...|.  |  .| ||..|||||.....
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGG

Pkinase 87912.m00115.AA Pkinase 22-273 28 3.6e-71 247.55 Pfam 1-293 (293) Show / Hide
Range on Protein: 22-273
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLFACKIISRKNQENYTFIYRLE-TEIRVLERIRHPGIVKIQDILYIDDLICIIMEYGRRG----MLYDYVI--NR
|. . .||.|....|   .| .| ...|.|||......    ....  .||... |..|| ||.. |. . .| |...||| . |     |.||.   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHL--PEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDFQP----KLVDFGLSYQA-LSDDDNYRRTFCGTLEYVAPESFEHKNYDGRKADIWS
| .  .|||. ...  .|  |||.|| .. |||||..|| . .. ..    |. ||||. |. .  .     |||||..|.|||   . .|.|.|.|.||
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGICYYSMLTCQYPWKGT-------DRGIMKAILAGEVEIPEQLS---------------------DRTKEVLKLLLTPDPEKRPTAREMLEL--M
.|.  | ||. . |..|        .. ... |. .... ... .                     .  |...| .|..||.|||||.. |.   .
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 87912.m00115.AA CAMKL 22-271 27 3.7e-71 226.28 In-house 1-293 (297) Show / Hide
Range on Protein: 22-271
Range on HMM: 1-293/297
Sequence Identity: 27% (80 aa)

YVPIHVIGEGASSVVVVVRH-SKTKDLFACKIISRKNQENYTFIYR------------LETEIRVLERIR---HPGIVKIQDILYIDDL------ICIIM
|  . ..|.|. ..|   .| . |.   | ||| .|   | ... .            .. ||. .....   || |.|. .... ..       |...|
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYGRRGM--LYDYVINRGH----LPEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDF--QPKLVDFGLS--YQAL-SDDDNYRRTFCGTLEYV
||   |   |.||....||    .||.|| ..   ..  ..|.|| ...|||.|..|| |...   . |..|||.|  |.     ...  .||||...| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

APESFEH--KNYDGRKADIWSLGICYYSMLTCQYPWKGTD---------RGIMKAILAGEVE-IPEQLSDRTKEVLKLLLTPDPEKRPTAREMLE
||| |.   | |||.|.||||.|.  | |.. ..|... .         .   | .   . . |. ..| . .  .. .|...||||||. . ..
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMN

Kinase 87912.m00115.AA MARK 22-271 34 8e-67 217.51 In-house 1-258 (262) Show / Hide
Range on Protein: 22-271
Range on HMM: 1-258/262
Sequence Identity: 34% (91 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLFACKIISR--KNQ-ENYTFIYRLETEIRVLERIRHPGIVKIQDILYIDDL---ICIIMEYGRRGMLYDYVINR-
|  . .||.|. ..| ...| .|.  .| ||. .  .|  ..   ..|   ||... .. || |.|  ..   |.    |..||||  .| ||||.... 
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMR---EIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHP

-GHLPEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDF--QPKLVDFGLSYQALSDDDNYRRTFCGTLEYVAPESFEHKNYDGRKADIWSLGIC
 |.|.| || .|   ..  ..|.||.|..|||.|..|| . ..   . |. |||.| .  .  ..   |||||..| ||| |. | |||.|.||||||. 
NGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPP--GQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVV

YYSMLTCQYPWKGTD---RGIMKAILAGEVEIPEQLSDRTKEVLKLLLTPDPEKRPTAREMLE
 | |.. ..|..|..     ..| ||.|. .||  .|.  .  ...|||..||.|||. | ..
LYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMK

Kinase 87912.m00115.AA Ciliate-E2 22-268 23 2.2e-58 199.04 In-house 1-358 (365) Show / Hide
Range on Protein: 22-268
Range on HMM: 1-358/365
Sequence Identity: 23% (86 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLFA--------------------CKIISRKNQENYTFIYRLETEIR-------------VLERIRHPGIVKIQDI
|  | .||.|. ..|  ... |.. .||                     . . .... .  .| . . ..|             .||.. || |.|. . 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LY--IDDLICIIMEYGRRGMLYDYVINR-----------GHLPEWEATKILVSLLN---------------TLEYLHSIN-VAHRDLKLDNIVLTQDFQP
 .   |. | ..|||   | |.|| .|.           . . | |. .|   .|.                |||||| | . |||.|..||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLVDFGLSYQALSDDDNYR------------------------------RTFCGTLEYVAPESFEHKNYDG--------RKADIWSLGICYYSMLTCQYP
|..||||| ..  | .|..                              .|.|||..|.||| .. |.||.         |.||||||.. | ||. ..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

WKGTDRGIMKAILAGEVEIP------------------EQLSDRTKEVLKL----LLTPDPEKRPT-ARE
.       .. |. .....|                  ...|. .|  .|     .|  |||||.| . .
F-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ

Kinase 87912.m00115.AA Ciliate-E2-Unclassified 22-268 22 1.2e-55 191.22 In-house 1-345 (352) Show / Hide
Range on Protein: 22-268
Range on HMM: 1-345/352
Sequence Identity: 22% (77 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLF-----ACKIISRK-NQENYTFIYRLETEIRVLER----------------IRHPGIVKIQDILYI--DDLICI
|  |..||.|. ..|  ..|.|.| ..     ..||...| .| ..     .  .... ..                . || .... .. .   .. |.|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMEYGRRGMLYDYVINRGH-----------------LPEWEAT-----KILVSLLNTLEYLHSIN-VAHRDLKLDNIVLTQD---FQPKLVDFGLSYQAL
.||| . | | .|  .|..                 ..| .|      ...  .|. |||||. | . |||.|..||.....   ...|. |||.|..  
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

SD--------------DDNYRRTFCGTLEYV----APESFEHKNYDGR---KADIWSLGICYYSMLTCQYPWKGTDRG-----------------IMKAI
..              ...   |||||..|     ||| .. .|||..   |.||||||.. | ||. .|| .....                  . . |
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LAGEVEIPE--------QLSDRTKEVLK----LLLTPDPEKRPTARE
.......|.        ..|.  |. ..     .|  .|.||.|. .
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQ

Kinase 87912.m00115.AA MELK 22-275 32 1.9e-48 163.56 In-house 1-254 (254) Show / Hide
Range on Protein: 22-275
Range on HMM: 1-254/254
Sequence Identity: 32% (82 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLFACKIISRKNQENYTFIYRLETEIRVLERIRHPGIVKIQDILYIDDLICIIMEYGRRGMLYDYVINRGHLPEWE
|   . || |  . | .  |  | .  | ||. ...  .   . |..||.  |  .||  | ..  ..  .| | ..|||   | ..||.| .  | | |
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHD--LPRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEE

ATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDFQPKLVDFGLSYQALSDDDNY-RRTFCGTLEYVAPESFEHKNYDGRKADIWSLGICYYSMLTCQY
. ...  ..  . |.||   |||||| .|.....|.. ||.||||  ..    | .   | || . | |||  . |.| |  ||.||.||  | ..    
TRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PWKGTDRGIM-KAILAGEVEIPEQLSDRTKEVLKLLLTPDPEKRPTAREMLELMYQ
|.      || | |. |  | |. ||  .|..|. .|  ||.||   ...|.  . 
PFDDDNMMIMYKKIMSGCYEEPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase 87912.m00115.AA RSK 25-275 29 5.5e-48 165.74 In-house 1-278 (278) Show / Hide
Range on Protein: 25-275
Range on HMM: 1-278/278
Sequence Identity: 29% (81 aa)

IHVI---GEGASSVVVVVRHSKTKDLFACKIISRKNQENYTF-IYRLETEIRVLERIR-HPGIVKIQDILYIDDLICIIMEYGRRGMLYDYVINRGH---
. |    | |. ...  ..|..|. ..| |.....   .    . .  ||...|||.. || ||.  .    .. . .|||| | | |..   ...|   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQ---DFQPKLVDFGLSYQALSDDDNYRRTFCGTLEYVAPESFE---HKN-YDGRKADIWSLG
. | ||  ..  .  ..|.||.  . |||||..||....   .   ||.|||.. |.  |. .   |||.|.||.|||      ... .| . .|.||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHD-KACDWWSLG

ICYYSMLTCQYPWKG----TDRGIMKAILAGE--VEIP--EQLSDRTKEVLKLLLTPDPEKRPT-----AREMLELMYQ
.  | ||| . | .|    .   ||| |. |.  ...|  . ||.  |. .. .|. ||.||..     | | .. .. 
VLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 87912.m00115.AA STE 22-271 22 2.6e-47 163.5 In-house 1-353 (359) Show / Hide
Range on Protein: 22-271
Range on HMM: 1-353/359
Sequence Identity: 22% (82 aa)

YVPIHVIGEGASSVVVVVRHSK---------------TKDLFACKIISRKNQEN--------------YTFIYRLETEIRVLERIR--HPGIVKIQDILY
.  | .||.||. .|.  .. |               |....| |... .|..|               . . ... ||... . .  || |||  .  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ID-------DLICIIMEYGRRGMLYDYVINR--------------GHLPEWEATKILVSLLNT-LEYLHSINVAHRDLKLDNIVLTQDFQPKLVDFGLSY
 .       | ..|.|||   | | | . ..              ...|| .  .|....|   |.|||| .. |||.| .|| |      ||.|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QALS---------------DDDNYRRTFCGTLEYVAPESFEH-----KNYDGRKADIWSLGICYYSMLTCQYPW-KGTDRGIMKAIL-------------
|  .               . .  | ||.||  . |||  .      ..  ..|.||||||..   |.| ..|| ....   | .|.             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---AGEVEIPE-------------------QLSDRTKEVLKLLLTPDPEKRPTAREMLE
    .   .|.                   ..|.  |. ... |. ||.||||| ..|.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLK

Kinase 87912.m00115.AA QIK 22-263 31 9.2e-47 161.67 In-house 1-260 (272) Show / Hide
Range on Protein: 22-263
Range on HMM: 1-260/272
Sequence Identity: 31% (82 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLFACKIISRKNQENYTFIYRLETEIRVLERIRHPGIVKIQDILYIDDLICIIMEYGRRGMLYDYVINRGH-----
|     || |   || . ||  ||   | |||  | | . . . ... |. .. ...|| |.|  ...  || . |..||   | ..||... |.     
YDIERTIGKGNFAVVKLARHRITKTKVAIKIID-KSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LPEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDFQPKLVDFGLSYQALSDDDNYRRTFCGTLEYVAPESFEHKNYDGR
               ..| || ..   ..   .|.|. |..|||||  || | ..   |..|||.|   ..  .    |.||.  | ||| || |.||| 
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFS--NWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGP

KADIWSLGICYYSMLTCQYPWKG-TDRGIMKAILAGEVEIPEQLSDRTKEVLKLLLTPDPEKR
|.||||.|.  |.. .   |  | |.    . .| | . ||  .|    .  .  |. |||.|
KVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHR

Kinase 87912.m00115.AA TyrKc 22-273 23 1.1e-14 14.61 SMART 1-280 (280) Show / Hide
Range on Protein: 22-273
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

YVPIHVIGEGASSVVVVVRHSKTKDLFACKIISRKNQENYTFIYRLETEIRVLERI--RHPGIVKIQDILYID-------DLICIIMEYGRRGMLYDYVI
 . ....||||  .|.  . .      | | .          .  .  |.|.. ..  .|| ||..  .   .       . ..|.|||   | | ||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NRGH-LPEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDFQPKLVDFGLSYQALSD------DDNYRRTF--CGT----LEYVAPESFEHKNYD
.... |.  .  .. .   .  ||||| |. ||||   |. .. ... |  |||||    .|      .| || .   .|     .   |||.. .. . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GRKADIWSLGICYYSMLT-CQYPWKG------TDRGIMKAILAG-EVEIPEQ--------LSDRTKEVLKLLLTPDPEKRPTAREMLELM
  | |.|| |.| . ..| .| |. |      ... ... . .|   ..|.          .|   .. |     |||.||| .|  |..
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 87912.m00115.AA Pkinase_Tyr 70-180 29 0.003456 11.42 Pfam 53-171 (270) Show / Hide
Range on Protein: 70-180
Range on HMM: 53-171/270
Sequence Identity: 29% (35 aa)

EIRVLERI-RHPGIVKIQDILY-IDDL--ICIIMEYGRRGMLYDYVIN----RGHLPEWEATKILVSLLNTLEYLHSINVAHRDLKLDNIVLTQDFQPKL
|....  . .|| ||.   . .  ..   |.|.|||   | |.||  .    ...|.  .  .. .   . .|||.|.|  ||||   |. .| ... | 
EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKI

VDFGLSYQALSDDDNY-RRT
 ||||.     .||.| | .
CDFGLARDI-YNDDYYYRKR

Kinase 87912.m00115.AA Pkinase_Tyr 258-273 50 0.288926 4.91 Pfam 255-270 (270) Show / Hide
Range on Protein: 258-273
Range on HMM: 255-270/270
Sequence Identity: 50% (8 aa)

PDPEKRPTAREMLELM
.|||.||| .| .| .
YDPEDRPTFSEIHEQL