Gene GL50803_102034 (G.lamblia)

GL50803_102034

Species: G.lamblia
Alias: GL50803_102034, GK295
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_102034.AA Protein None 978 None Fasta, JSON
GL50803_102034.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of GL50803_102034.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_102034.AA NEK 229-262 30 4.2e-07 21.5 In-house 251-286 (286) Show / Hide 
Range on Protein: 229-262
Range on HMM: 251-286/286
Sequence Identity: 30% (11 aa)

SS--YSSQLVDMISSCLSSDPSRRPKAAELSSYSLA
|   ||..| ..||..|  ||. || . .. . .. 
SHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_102034.AA STE 198-262 19 4.3e-07 21.24 In-house 251-359 (359) Show / Hide 
Range on Protein: 198-262
Range on HMM: 251-359/359
Sequence Identity: 19% (21 aa)

IWALGCLA-------WSFADPQSFYSKEQLA----------------ADP---EVHLS----------------SYSSQLVDMISSCLSSDPSRRPKAAE
|| |||..         ..| . ..   . .                 .|   . |||                ..|. . | |. ||  ||. ||.| .
IWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ

LSS--YSLA
| .   .  
LLKSEHPFI
Kinase GL50803_102034.AA NEK8 229-262 29 1e-06 15.04 In-house 245-278 (278) Show / Hide 
Range on Protein: 229-262
Range on HMM: 245-278/278
Sequence Identity: 29% (10 aa)

SSYSSQLVDMISSCLSSDPSRRPKAAELSSYSLA
. ||. .  ....||. || .|| |... .. | 
DHYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC
S_TKc GL50803_102034.AA S_TKc 9-269 17 6e-06 -90.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-269
Range on HMM: 1-231/231
Sequence Identity: 17% (50 aa)

YKDSRFIRETDSYSIFSAVRISDDVHVSILRLPVKPEHATTIIAALEKYRSVVIEKHSVLLDCYDACYMPADDLLLLELEPGFHETAADLLLRVKD--AQ
|.  | | .    . . .. .... .| | ...   ||.   |. |.|       .|  .  .||...   .  . .|. .|   .  |.. . .    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---EHIRREIQILKK-------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

FQVPEDAIWEIVSQLAQAISYCYNP-------------LNNLEPSMWSFIHPARII-----RIETGHIKLFNPHIMTTFFSTENCASFASFTPPECRHSA
|. ||  .. .. |...|. || .              |..             |.     |.             |||  |        . .||     
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE----------HIKICDFGLARQL------------TTFCGT------PWYMAPEVL---

QGTATE-PAAIWALGCLAWSFADPQS-FYSKEQLAADPEVHLSSYSSQLVDMISSCLSSDPSRRPKAAELSSYSLAIKANARL
    .  .. .|..||. . ..  .  |.  .|.  .  .     |... |.|. ||  ||..|| | |.  . ..||.   .
--GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_102034.AA NAK 229-260 34 1.2e-05 14.78 In-house 268-299 (299) Show / Hide 
Range on Protein: 229-260
Range on HMM: 268-299/299
Sequence Identity: 34% (11 aa)

SSYSSQLVDMISSCLSSDPSRRPKAAELSSYS
| ||.|. | |. .|  ||..||. ...... 
SRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase GL50803_102034.AA FRAY 237-262 46 1.5e-05 12.87 In-house 252-277 (277) Show / Hide 
Range on Protein: 237-262
Range on HMM: 252-277/277
Sequence Identity: 46% (12 aa)

DMISSCLSSDPSRRPKAAELSSYSLA
.||..||  |||.|| |.||  ..  
KMIEKCLQKDPSKRPTASELLKHKFF
Kinase GL50803_102034.AA NEK10 231-265 31 1.8e-05 13.76 In-house 245-279 (279) Show / Hide 
Range on Protein: 231-265
Range on HMM: 245-279/279
Sequence Identity: 31% (11 aa)

YSSQLVDMISSCLSSDPSRRPKAAELSSYSLAIKA
.| .. ..|..||  ||. ||   . ||    |. 
WSDDVRFTITRCLTPDPEARPDIVKVSSVLRMIQD
Kinase GL50803_102034.AA YSK 229-262 35 4.9e-05 10.7 In-house 224-257 (257) Show / Hide 
Range on Protein: 229-262
Range on HMM: 224-257/257
Sequence Identity: 35% (12 aa)

SSYSSQLVDMISSCLSSDPSRRPKAAELSSYSLA
.|||  . . .  ||  ||. || | || ...  
RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase GL50803_102034.AA STE20 229-256 35 0.000165 12.73 In-house 255-282 (288) Show / Hide 
Range on Protein: 229-256
Range on HMM: 255-282/288
Sequence Identity: 35% (10 aa)

SSYSSQLVDMISSCLSSDPSRRPKAAEL
...|... |....||  ||. || | .|
HKWSPEFHDFVDKCLQKDPEKRPTASQL
Kinase GL50803_102034.AA STE7 224-262 27 0.000231 12.21 In-house 251-288 (288) Show / Hide 
Range on Protein: 224-262
Range on HMM: 251-288/288
Sequence Identity: 27% (11 aa)

PEVHLSSYSSQLVDMISSCLSSDPSRRPKAAELSS-YSLA
|. .  ..|  ..| .. || .||. |||  .|    .  
PRLP--KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI
Kinase GL50803_102034.AA STE-Unique 229-262 23 0.000297 10.36 In-house 583-616 (616) Show / Hide 
Range on Protein: 229-262
Range on HMM: 583-616/616
Sequence Identity: 23% (8 aa)

SSYSSQLVDMISSCLSSDPSRRPKAAELSSYSLA
.... .... | .||. .|. ||.|..|    . 
PKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase GL50803_102034.AA NEK 97-128 23 0.214445 1.15 In-house 93-130 (286) Show / Hide 
Range on Protein: 97-128
Range on HMM: 93-130/286
Sequence Identity: 23% (9 aa)

DLLLR---VKDAQ---FQVPEDAIWEIVSQLAQAISYC
||  .    |  .      .|. ||..  |.. |. |.
DLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYM
Ank GL50803_102034.AA Ank 386-411 30 3.580635 4.88 Pfam 1-25 (33) Show / Hide 
Range on Protein: 386-411
Range on HMM: 1-25/33
Sequence Identity: 30% (8 aa)

AERTSLMNAAAAGNVELVREFLHEAG
  .| |. |.  |..| |...|  .|
DGFTPLHLACRCGHTEVVKMLLQ-HG
Ank GL50803_102034.AA Ank 416-448 36 3e-06 26.67 Pfam 1-33 (33) Show / Hide 
Range on Protein: 416-448
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

YGKTALMLAAEGGHYECVRLLLIEAGYVDLENK
.| |.|.||.. ||.|.|..||     |.. ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_102034.AA Ank 536-556 38 3.091708 5.11 Pfam 1-21 (33) Show / Hide 
Range on Protein: 536-556
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

DGTTLLMLLVEANCKEGVEAL
|| | |.| .. ...| |. |
DGFTPLHLACRCGHTEVVKML
Ank GL50803_102034.AA Ank 768-800 27 4.227043 4.62 Pfam 1-33 (33) Show / Hide 
Range on Protein: 768-800
Range on HMM: 1-33/33
Sequence Identity: 27% (9 aa)

TEATPLISAALNSNETELRLLLKHDSDFLRNDF
   |||  |... ..  ...||.|  |    | 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_102034.AA Ank 846-868 30 0.961271 6.94 Pfam 1-23 (33) Show / Hide 
Range on Protein: 846-868
Range on HMM: 1-23/33
Sequence Identity: 30% (7 aa)

NGMTALGAAASVGNVHCLMLLLG
.|.|.|  |.. |.. .. .||.
DGFTPLHLACRCGHTEVVKMLLQ
Ank GL50803_102034.AA Ank 876-897 36 3.8e-05 22.83 Pfam 1-22 (33) Show / Hide 
Range on Protein: 876-897
Range on HMM: 1-22/33
Sequence Identity: 36% (8 aa)

NGMTALMYAAKHGRRECLRLLL
.|.|.|..|...|. |....||
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_102034.AA Ank 906-927 45 0.000121 21.01 Pfam 1-22 (33) Show / Hide 
Range on Protein: 906-927
Range on HMM: 1-22/33
Sequence Identity: 45% (10 aa)

DGETALILAAKHGHAACVELLM
||.|.| ||...||. .|..|.
DGFTPLHLACRCGHTEVVKMLL