GL50803_104150

Species: G.lamblia
Alias: GL50803_104150, GK066
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: PLK
Subfamily: PLK1

Sequence

Name Sequence Type Origin Length Description Download
GL50803_104150.AA Protein None 678 None Fasta, JSON
GL50803_104150.kin_dom Protein Kinase Domain None 288 None Fasta, JSON

Protein domain

Protein domains of GL50803_104150.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_104150.AA S_TKc 22-309 28 4.7e-82 279.84 SMART 1-231 (231) Show / Hide
Range on Protein: 22-309
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNG--GTLTDLIRRRKH---
|. ....|||.|. ||  ......  .|.|| .          ...  |. |..   ||||.. . || |  ..|...| |.|  |.| |.|..|..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVIYSHIMKRKASGRGPDPNLDED
   ..| .|||. . |..|| |.|.. |||||.| .||.| |   .|..||||| .         |.||||.... ||.                     
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---------------------

CVNLCHQLLPAYSGQGHSF-SADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLD-------
               |... ..|.||.||... |..|.|||.  ......|.|.            |...|.||...|. ||.|| |. |.|        
---------------GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HSWL
| |.
HPWF

Kinase GL50803_104150.AA CAMK 27-309 19 6.6e-81 260.29 In-house 1-425 (425) Show / Hide
Range on Protein: 27-309
Range on HMM: 1-425/425
Sequence Identity: 19% (85 aa)

LLGKGGFAYVYEFHDVNSD------------SSYACKITPRSALQK-------------------------KKYYDKFVTEVTIHRGLV-------HPNI
 ||.|.|. |..  . |.               .|.|| ... |..                          |  ...  |. |.. |        ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CRVLNVFKD-------------------QMNYYIIL---EKCNGG----TLTDLIRRRKH---------------LTETEARFFSKRILNALWYLHDLYI
.. . |. |                   ....|...   | | ||     | | |.....               .|| |||.. . |. |. |.|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKTSNIFLMED-----------------FDVKVGDFGLAVKCET-----------------------PEELHWTMCGTPNFLP-SEVIYSHIMKRK
.|||.|  || | ..                 ...|. |||.| |..                        . .. .|.|||| . .  ||. .  .. .
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

ASGRGPDPNLDEDCVNLCHQLLPAYSGQGHSFSADMWSFGCLVFSMIYGRPPFEAA-------------DIKTTYKRIVRCDFSFPGS------------
  . .                  .   .......|||| |.. . |  |.|||..              ... ....| .....|| .            
Q-N-A-T----------------DEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPE

----ISVS------EDLKNFIKGLLTPDPRKRFTVKECLDHSWL
    || .      .. |..|...|..|| ||.|...||.| |.
WWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Pkinase GL50803_104150.AA Pkinase 22-309 28 4.3e-80 277.19 Pfam 1-293 (293) Show / Hide
Range on Protein: 22-309
Range on HMM: 1-293/293
Sequence Identity: 28% (94 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFV-TEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGG----TLTDLIR--RR
|. |. .|.|.|. ||. |....   .|.|| ...   ..| . ..  .|. |.. | ||||.| . .| |  ..|...| |.||     | |.|.  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KHL--TETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDV----KVGDFGLAVKC-ETPEELHWTMCGTPNFLPSEVIYSHIMKRKASGRGPD
. .  .| |..|. . || .| |.|.  |||||.| .||.. .. ..    |..||||| .  . . .  .| ||||.... |||               
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--------------

PNLDEDCVNLCHQLLPAYSGQGHSFSADMWSFGCLVFSMIYGRPPFEAA------DIKTTYKRIVRCDFSFPGSISVS-------------------EDL
                  .||... ..||||.||... |. |||||  .      | .  ..|| .....|. . . |                   |..
------------------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC

KNFIKGLLTPDPRKRFTVKECLDHSWL
| |||..|..|| || | ...| | |.
KDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase GL50803_104150.AA PLK 22-186 46 8.8e-77 249.58 In-house 1-166 (258) Show / Hide
Range on Protein: 22-186
Range on HMM: 1-166/258
Sequence Identity: 46% (77 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRR-KHLTET
|. |..||||||| .||. |. ..  || |. |.| .||.. ..|   |. ||| | |||| .  ..| |. | || || |....| ....|| |.|||.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNF
|.|..   | ..| |||.  |||||.| .|.|| ..  ||.||||||...| ..| . |||||||.
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNY

Kinase GL50803_104150.AA PLK-Unclassified 22-185 45 1.9e-67 230.42 In-house 1-171 (264) Show / Hide
Range on Protein: 22-185
Range on HMM: 1-171/264
Sequence Identity: 45% (77 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRR-------
|. |..||||||| .|.. .. .   || || | | |.|.. . |   |  ||  | |.|| . . .| |. | || || |..||| ..|.||       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

KHLTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPN
| |||.|.....  |..|| |||.  ||||| |  |||| ..  || .|||||.| |  .|   | |||||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPN

Kinase GL50803_104150.AA PLK1 22-192 45 2.3e-62 203.68 In-house 1-171 (253) Show / Hide
Range on Protein: 22-192
Range on HMM: 1-171/253
Sequence Identity: 45% (77 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRRKHLTETE
|. |. |||||||  ||..|.. .  .| |. |.| | |..  ||   |..||| | |..| .. . | |. | ||.|| |.   | .| .||| .|| |
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLMELHKRRKAITEPE

ARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVI
.|.. . |...  |||.. |||||.|  |.|| ....||.|||||| |||   |   |.|||||..  ||.
CRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVL

Kinase GL50803_104150.AA PLK2 22-192 43 2.5e-56 179.79 In-house 1-175 (257) Show / Hide
Range on Protein: 22-192
Range on HMM: 1-175/257
Sequence Identity: 43% (76 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNG----GTLTDLIRRRKHL
|. ||||||||||  ||  |  . . || || |.|   | .   |   |. .|| | |..| .    | |. | ||.|| |        .      |.||
YCRGKLLGKGGFARCYEMTDMDTHYVYAVKIVPHSRVAKPHQREKMEREIELHRQLRHRHIVQFHHHFEDRDNIYILLEYCSRQVPLKSMAHMWKVRHHL

TETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVI
|| | |.. . |.  | |||.  ||||| | .| |. .   ||.|||||| . | .|. | |||||||..  ||.
TEPEVRYYMRQIVSGLRYLHQQCIIHRDLKLGNFFINDNMEVKIGDFGLAARLEPEEHCHRTMCGTPNYIAPEVL

Kinase GL50803_104150.AA SAK 22-192 39 6.9e-44 147.2 In-house 1-172 (254) Show / Hide
Range on Protein: 22-192
Range on HMM: 1-172/254
Sequence Identity: 39% (68 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGLVHPNICRVLNVFKDQMNYYIILEKCNGGTLTDLIRRR-KHLTET
|. ..|||||||| ||  . .      | |.  . ..||    ..   || ||  | || |  . | |.|.   |..|| |  | .   ...| .  ||.
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVI
||| | ..|.  . |||   |.|||.  ||| |  | ..|. ||||| . . |.| |.|||||||..  |..
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIA

Kinase GL50803_104150.AA CAMKL 22-186 29 3e-43 135.77 In-house 1-199 (297) Show / Hide
Range on Protein: 22-186
Range on HMM: 1-199/297
Sequence Identity: 29% (58 aa)

YRPGKLLGKGGFAYVYEFHD-VNSDSSYACKITPRSALQKKKYYDKF------------VTEVTIHRGLV---HPNICRVLNVFKDQMN------YYIIL
|| || ||||.|. |   ..  .    .| ||  .. .... . .|               |. |.. |    ||||.. . |. .. .      .|...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EKCNGGT--LTDLIRRRKH----LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFD--VKVGDFGLAVKCET----PEELHWTMCGTPNF
| | ||   | | |....|    ..| |||.. . |. |. |.|.. |.|||||  || | |. .  .|. |||.. ...     |...  | ||.|..
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

Kinase GL50803_104150.AA CAMK-Unique 22-192 23 3.1e-40 130.41 In-house 1-261 (363) Show / Hide
Range on Protein: 22-192
Range on HMM: 1-261/363
Sequence Identity: 23% (61 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYD-----------------KFVTEVTIHRGLVHPNICRVLNV----FKDQM-------
|. ....|.|.|  ||| .|      .|||.    . . ||..                  |.  |. | . . |||| ... .    | |         
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NYYIILEKCNGGTLTDLIRR--------------------RKHLTE--TEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFD-----
        ..||..| |.||.| |.| .                    . |..|  ....| . ..| |. |.|.. |.|||.|  || . . |.     
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-----------VKVGDFGLAVKCETPEELH--WTMCGTPNFLPS--------------EVI
           .|. ||||... .. .. |   |||||| ..                |||
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVI

Kinase GL50803_104150.AA Ciliate-E2 22-192 23 1.2e-38 130.22 In-house 1-259 (365) Show / Hide
Range on Protein: 22-192
Range on HMM: 1-259/365
Sequence Identity: 23% (63 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYA----------------CKITPRSALQKKKYYDKFV-TEVTIHRGLV----------------HPNICRVLNV
|   |..|.|.|. ||.  . . .  .|                .||      ..||.  ...  |  | | .                 ||||..   .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FK--DQMNYYIILEKCNGGTLTDLIRRRKH-----------LTETEARFFSKRILN---------------ALWYLHDLY-IIHRDIKTSNIFLMEDFDV
|.  |. |.|...| |.||.| |.|. .|.           .|| |.....| ||.               || |||    ||||||| .||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVGDFGLAVKCETP-------------------------------EELHWTMCGTPNFLPSEVI
|. ||||. |. ..                               .....| ||||.... |..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEIL

Kinase GL50803_104150.AA ULK 22-167 31 9.5e-38 131.54 In-house 1-185 (324) Show / Hide
Range on Protein: 22-167
Range on HMM: 1-185/324
Sequence Identity: 31% (58 aa)

YRPGKLLGKGGFA-YVYEFHDVNS---DSSYACKITPRSALQKKKYY-------DKFVTEVTIHRGLV---HPN--ICRVLNVFKDQ--MNYYIILEKCN
|   . |||| |. .||.  ....   .  .|||. ... ..|||.        ...  |. | . |    |||  |.. . .|...   |.|||.| ||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGTLTDLIRRRKH---------LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFD------------VKVGDFGLA
||.| ..| ..|.         |.| ||. | | |.|.. .||.  ||||||| .|| . ...             .|..|||.|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA

Kinase GL50803_104150.AA PLK 228-309 40 1.6e-34 109.91 In-house 177-258 (258) Show / Hide
Range on Protein: 228-309
Range on HMM: 177-258/258
Sequence Identity: 40% (33 aa)

QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL
||||. .|.||.|| .  .. |.||||..|.|.|||||. ...||| .. .|  .|..|. .| ..|..|.| .. |.| ..
QGHSYEVDCWSLGCIMYTLLIGKPPFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF

Kinase GL50803_104150.AA PLK-Unclassified 228-309 39 4e-31 109.74 In-house 183-264 (264) Show / Hide
Range on Protein: 228-309
Range on HMM: 183-264/264
Sequence Identity: 39% (32 aa)

QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL
||||.  |.||||| .  .. |.||||. |.|.|||.|   ..|||  . .|  .|..|.  |...| .|.|  . ..|...
QGHSYEVDCWSFGCILYTLLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY

Kinase GL50803_104150.AA CAMKL 232-309 26 4.2e-24 73.67 In-house 215-297 (297) Show / Hide
Range on Protein: 232-309
Range on HMM: 215-297/297
Sequence Identity: 26% (23 aa)

FSADMWSFGCLVFSMIYGRPPFEAA--------DIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL
. .|.|| | . . |..|. ||...        .| . |..| .. . .|  ..|| |....|...|...| ||.|... . | |.
PKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM

Kinase GL50803_104150.AA Ciliate-E2 227-309 25 9.8e-24 78.34 In-house 270-365 (365) Show / Hide
Range on Protein: 227-309
Range on HMM: 270-365/365
Sequence Identity: 25% (27 aa)

GQGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFP----------------GSISVSEDLKNFIKG----LLTPDPRKRFT-VKECLD
..|.....|.||.|.. . |..|.|||        .. |  |...||                   ..|.. |..||     .|  || ||.|  ...|.
QKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN

HSWL
| |.
HPWF

Kinase GL50803_104150.AA CAMK-Unique 234-309 27 1.5e-22 71.06 In-house 274-363 (363) Show / Hide
Range on Protein: 234-309
Range on HMM: 274-363/363
Sequence Identity: 27% (25 aa)

ADMWSFGCLVFSMIYGRPPFEAADIK--------TTYKRIVRCDF-SFPG---SIS--VSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL
.| || | . ..|. |.|||......         ....|  .|. .|.    ...  .|. .|.|.|...| || .| . || |.|.|.
SDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI

Kinase GL50803_104150.AA PLK1 228-309 35 4.3e-22 69.18 In-house 174-253 (253) Show / Hide
Range on Protein: 228-309
Range on HMM: 174-253/253
Sequence Identity: 35% (29 aa)

QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL
.||||  |.|| ||... ...|.||||.  .| ||.|| ..... |   ..|.  ...|. .| ||| .| |... |   ..
KGHSFEVDIWSIGCIMYILLFGQPPFETKCLKETYSRIKKNEYRIP--SHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF

Kinase GL50803_104150.AA PLK2 228-309 35 1.2e-20 62.91 In-house 178-257 (257) Show / Hide
Range on Protein: 228-309
Range on HMM: 178-257/257
Sequence Identity: 35% (29 aa)

QGHSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL
||||. .| |. ||  . |  ||||||.|. | ||..|    . .| . | .   .  |  .| |||. |    . ..|   
QGHSCESDIWALGCIMYTMLCGRPPFETANLKETYRCIRHNHYHMPTHLSPP--ARHLIARMLSPDPEDRPSLDHIIRHDFF

Kinase GL50803_104150.AA ULK 227-309 24 2.1e-19 65.58 In-house 221-324 (324) Show / Hide
Range on Protein: 227-309
Range on HMM: 221-324/324
Sequence Identity: 24% (26 aa)

GQG----HS-FSADMWSFGCLVFSMIYGRPPFEAADIKTTYK------------RIVRCD--FSFP---GSISVSEDLKNFIKGLLTPDPRKRFTVKECL
|||    .. . .|.||.||. . |.||..||..  . ..|.             |  ..  . ||    .. .|...|..|...|. |...|..  | .
GQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIF

DHSWL
.| |.
NHPWF

Kinase GL50803_104150.AA SAK 230-309 27 2.2e-17 55.54 In-house 177-254 (254) Show / Hide
Range on Protein: 230-309
Range on HMM: 177-254/254
Sequence Identity: 27% (22 aa)

HSFSADMWSFGCLVFSMIYGRPPFEAADIKTTYKRIVRCDFSFPGSISVSEDLKNFIKGLLTPDPRKRFTVKECLDHSWL
|   .|.|| ||... .. |||||.   .|.|  ...  ..  |  .|.  . .  |. .|  .|  | |..  |.| ..
HGLQSDVWSLGCMLYTLLIGRPPFDTDAVKNTLNKVMMAEYIMPAHLSM--EAQDLIHKMLRKNPHERITLSTVLCHPFM

Kinase GL50803_104150.AA TyrKc 22-309 20 2.6e-10 -55.96 SMART 1-280 (280) Show / Hide
Range on Protein: 22-309
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

YRPGKLLGKGGFAYVYEFHDVNSDSSYACKITPRSALQKKKYYDKFVTEVTIHRGL--VHPNICRVLNVFKDQ-------MNYYIILEKCNGGTLTDLIR
 . || || | |  ||. .        | |    .|         |  |  | . |   |||| | . |  .|         ..|..| . .| | | .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RRKH-LTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLAVKCETPEELHWTMCGTPNFLPSEVIYSH-IMKRKASGRGPDPNL
.... |.  .   |.  | .   |||.  .||||. . |. . |.. ||..||||. .                      ||..  .           . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRD----------------------IYDDDQQG---------ESK

DEDCVN---LCHQLLP-------AYSGQGHSFSADMWSFGCLVFSMI-YGRPPFEA-----ADIKTTYKRIVRCDFSFPGSI-------SVSEDLKNFIK
|   .     .. .||       .      ..  | |||| . . .  || .| .       . .  .... . .   .            .... . .|
DYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMK

GLLTPDPRKRFTVKECLDHSWL
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QCWHEDPEDRPTFSEI--HECF

Kinase GL50803_104150.AA Pkinase_Tyr 79-167 32 4e-05 17.97 Pfam 63-158 (270) Show / Hide
Range on Protein: 79-167
Range on HMM: 63-158/270
Sequence Identity: 32% (31 aa)

HPNICRVLNVFK-DQMN--YYIILEKCNGGTLTDLIRR----RKHLTETEARFFSKRILNALWYLHDLYIIHRDIKTSNIFLMEDFDVKVGDFGLA
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HPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA

POLO_box GL50803_104150.AA POLO_box 442-478 46 8.8e-10 39.73 Pfam 1-39 (74) Show / Hide
Range on Protein: 442-478
Range on HMM: 1-39/74
Sequence Identity: 46% (18 aa)

YSNRYGFAYQISNGSIGVI-FNDESAAILSPNAL-IVDY
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YRTKYGIMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTY

POLO_box GL50803_104150.AA POLO_box 575-636 19 0.000475 18.56 Pfam 7-74 (74) Show / Hide
Range on Protein: 575-636
Range on HMM: 7-74/74
Sequence Identity: 19% (13 aa)

LCLLFNTKVFQVN-FADHSKVV--VAHR-SVTFMS--EKREIYTYPSEYLKDDRFSFKELRRRVDRAR
.  ..... .||| | ||.|..     . .||...  .... .||| . .  . .  ..|....  ..
IMYQLSNGTVQVNFFNDHTKIILCPNMKYAVTYIDHDPNWQRQTYPLSTILEHGCYPEDLQKKLTYLK