Gene GL50803_113522 (G.lamblia)

GL50803_113522

Species: G.lamblia
Alias: GL50803_113522, GK002
External Links: GiardiaDB ,
Annotation:

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
GL50803_113522.AA Protein None 1514 None Fasta, JSON
GL50803_113522.kin_dom Protein Kinase Domain None 299 None Fasta, JSON

Protein domain

Protein domains of GL50803_113522.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_113522.AA AGC 15-313 24 3.4e-82 211.5 In-house 1-395 (395) Show / Hide 
Range on Protein: 15-313
Range on HMM: 1-395/395
Sequence Identity: 24% (102 aa)

FDVIDFLGEGSYGKVYRAIDA------ETGLEVGLKVINRKA-LENDK--LLYTLDRE------------VVALRTAQNKNLT--------NIIR-LYSK
|...  .|.||.|||| . .        ||    .||.. |     .|   .    .|               | ......          .|.. |.. 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTH-NHPIKSHHPFIVKILHYS

TDKNDF--TTLILEYAS--------LGDLSSLIKCY-R----VLPEDWTRFLIAE-------IILGLEGLHS-IGYCHRD-IKPSNILLTRGGHVRIADF
   .|     ...||..         |.. ...  . |    ...|...|| .||       |.|.|| |||  |. ||| .|| ||||.. ||....||
FQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDF

GTSKQLPLDE---------------VSMAIGTKSFPPSAYMSTSSAAASNDSQGTLQKKLQNMDQQP--------------RCSIYG--TVCYNAPESNR
| .|... |.                .   . ||              ..| . .  ....|....                 .. |  |  | |||   
GLCKEGMNDGEKGQQSQSNMKFHWHNKKY-Q-KS--------------NMD-T-NK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-

HGLLYMSPQDVWG--LGCILYECLTGMPAFMGD----------VELAIMQAIE------KQKVIVP----------KTVSPDAADLIKRLLTKDPTKRFN
    |  . | |.  |||..|| ||| | | ||           .  ..| |.      ..||  |          . .||.| ||||.||.|||.||  
----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLG

G--------GWRAIKKHPFF
         |   ||.||.|
CGGNDFGDKGAEEIKNHPWF
S_TKc GL50803_113522.AA S_TKc 15-313 27 1.7e-71 244.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-313
Range on HMM: 1-231/231
Sequence Identity: 27% (86 aa)

FDVIDFLGEGSYGKVYRAIDAETGLEVGLKVINRKALENDKLLYTLDREVVALRTAQNKNLTNIIRLYSKTDKNDFTTLILEYASL--GDLSSLIKCYRV
..... .|.|..||||.... .|| .| .|.|.           .. ||.  |.     .  ||..||   .  |.  ...||..   ||| ..|| .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------LPEDWTRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTRGGHVRIADFGTSKQLPLDEVSMAIGTKSFPPSAYMSTSSAAASNDSQGTLQKKLQ
      .|| ..||....|...|| .|| | .|||.||.||||..  |. |.||| ..||                                        
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------------------------

NMDQQPRCSIYGTVCYNAPESNRHGLLYMS-PQDVWGLGCILYECLTGMPAFMGDVELAIMQAIEKQKVIVPKTVSPDAADLIKRLLTKDPTKRFNGGWR
        .. ||  | |||       |   . |.| .||||||.|.| | |    . .... |           ||.| |.|...|.|||.||   .  
-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRP--TA-

AIKK-------HPFF
 . .       ||.|
EALQDEWDIKCHPWF
Kinase GL50803_113522.AA Pkinase 15-313 24 2.1e-54 191.82 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-313
Range on HMM: 1-293/293
Sequence Identity: 24% (84 aa)

FDVIDFLGEGSYGKVYRAIDAETGLEVGLKVINRKALENDKLLYTLDR--EVVALRTAQNKNLTNIIRLYSKTDKNDFTTLILEYASLG----DLSSLIK
. ..  .|.||.|.||....  || .| .|.|...  |... ..|. |  |.  ..  . .|   ... .     .|   ...||.  |    ||...|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDYIS

--CYRVL--PEDWTRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTRGGHV----RIADFGTSKQLPLDEVSMAIGTKSFPPSAYMSTSSAAASNDSQGT
   ....  .|.  .| . .|. ||| .|| | .|||.||.|||. . ||.    .|.||| .||.                                  
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------------------------------

LQKKLQNMDQQPRCSIYGTVCYNAPESNRHGLLYMSPQDVWGLGCILYECLTGMPAFMGD------VELAIMQAIEKQKVIVPKTVS-------------
      .  ..   .. ||  | |||  |.|  | .. |.|..|||||| |.| | | |.       ...... | . ..  .   .             
------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHF

--------PDAADLIKRLLTKDPTKRFNGGWRAIKKHPFF
        ... |.||..|.|||.|| .  .. |..||.|
HWTFHNWSEECKDFIKWCLCKDPKKRPT--AEQILQHPWF
Kinase GL50803_113522.AA CAMK 20-313 18 3.8e-52 165.95 In-house 1-425 (425) Show / Hide 
Range on Protein: 20-313
Range on HMM: 1-425/425
Sequence Identity: 18% (86 aa)

FLGEGSYGKVYRAIDAETG------------LEVGLKVINRKALEN-------------------------DKLLYTLDREVVALRTAQNKN----LTNI
 ||.||.|||...|. .|.             .|  |.|..| | .                         .| .  . ||.  ... |...      ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYS---------------KTDK-----NDFTTLIL---EYASLG----DLSSLIKCY---------------RVLPEDWTRFLIAEIILGLEGLHSIG
|.||                  .|     ...  ...   ||.| |    || . |.                 . ..|. .|...  |. ... .|| .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

YCHRDIKPSNILL-TRG----------------GHVRIADFGTSKQLPLDE----------------VSMAIGTKSFPPSAYMSTSSAAASNDSQGTLQK
 .|||.|| |||| ...                . . |.||| ..... .|                .                                
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW--------------------------------

KLQNMDQQ----PRCSIYGTVCYNA-PESNRH-------------GLLYMSPQDVWGLGCILYECLTGMPAFMGDVELAIMQ-------------AIEKQ
     ..     .     || .| | ||  .                 |  . |.| .|.||| .|.| | | || .  |..              | | 
-----TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKG

KVI-VPKT-----------------------VSPDAADLIKRLLTKDPTKRFNGGWRAIKKHPFF
|    |.                        ||... |||...|..||.||..     ...||..
KYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMT--IEQCLNHPWM
Kinase GL50803_113522.AA Ciliate-E2-Unclassified 15-313 22 4.5e-44 150.78 In-house 1-352 (352) Show / Hide 
Range on Protein: 15-313
Range on HMM: 1-352/352
Sequence Identity: 22% (88 aa)

FDVIDFLGEGSYGKVYRAIDAETGLEVGLKVINRKALENDKLLY-TLDREVVALRTAQNKN--------------------LTNIIRLYSKTDKNDFTTL
. .|  .|.|..||||.... ... ..  . .. |. ....... . | | .   .. |..                      .|....    . .   .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

ILEYASLGDLSSLIKCY-----------------RVLPEDWTR-----FLIAEIILGLEGLHSIG-YCHRDIKPSNILLTRGG---HVRIADFGTSK---
..||.  |||.  || .                 . ..|  ..     |..|.|..||| ||. .  .||||||.|||.. .|   ...|.||| ||   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

--------QLPLDEVSMAIGTKSFPPSAYMSTSSAAASNDSQGTLQKKLQNMDQQPRCSIYGTVCYN----APESNRHGLLYM-SPQ-------DVWGLG
        |                                    | |.|. .||  ... || .|     |||     .|    .        |.|.||
QNNNCDTNQ------------------------------------QQKMQIWKQQMMWTFCGTPNYMPQYTAPE-----VLQGQNYDHSKAYKCDIWSLG

CILYECLTGMPAFMGDVELA---------------IMQAIEKQKVI---------VPKTVSPDAADLIK----RLLTKDPTKRFNGGWRAIKKHPFF
.||||.|.| . | .  .                 ... . ||| |         .||..|| |.|.|.    ..| |.| ||   ..  |..||.|
VILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI--TFEQILNHPWF
Kinase GL50803_113522.AA RSK 18-313 28 3.2e-42 146.58 In-house 1-278 (278) Show / Hide 
Range on Protein: 18-313
Range on HMM: 1-278/278
Sequence Identity: 28% (90 aa)

IDFLGEGSYGKVY---RAIDAETGLEVGLKVINR-KALENDK-LLYTLDREVVALRTAQ-NKNLTNIIRLYSKTDKNDFTTLILEYASLGDLSSLIKCYR
.  ||.|.||||.   . ..  || .   ||... |.  ..| . .|. .|.  | . |  .   .|..|.   . .. . ||.|| . |.|   ..  .
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTM-TERNILERCQQHP---FIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEK

V---LPEDWTRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTR---GGHVRIADFGTSKQLPLDEVSMAIGTKSFPPSAYMSTSSAAASNDSQGTLQKKL
    . ||  .| .|||.| .| ||. |  |||.||.|||..     ||... ||| .||...|. ...                               
HFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT-----------------------------

QNMDQQPRCSIYGTVCYNAPESNR---HGLLYMSPQDVWGLGCILYECLTGMPAFMG---DVELAIMQAIEKQK--VIVP--KTVSPDAADLIKRLLTKD
            .|. | |||  .   ..  .    |.| ||...|| ||| | | |   .    ||. |.| |  .  |  ...|..| |||...|..|
----------FCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRD

PTKRFN---GGWRAIKKHPFF
| || .   ..   ||.||.|
PHKRLGCGPQDAEEIKQHPWF
Kinase GL50803_113522.AA CAMKL 15-161 29 1.1e-36 114.44 In-house 1-174 (297) Show / Hide 
Range on Protein: 15-161
Range on HMM: 1-174/297
Sequence Identity: 29% (52 aa)

FDVIDFLGEGSYGKVYRAID-AETGLEVGLKVINRKALEN-------------DKLLYTLDREVVALRTAQNKN-LTNIIRLYSKTDKNDF------TTL
..... ||.||.|||  |..   || .|  |.|..| . |             .. .  . ||.  ..  . .    |||.||   .  ..        |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYL

ILEYASLGD--LSSLI---KCYR-VLPEDWTRFLIAEIILGLEGLHSIGYCHRDIKPSNILLT-RGG-HVRIADFG
..||.| |.  |   |   .. |  .||. .|..   |. ... .|| | .|||||| ||||. .|   . |.|||
VMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFG
Kinase GL50803_113522.AA ULK 15-166 28 1.7e-33 114.29 In-house 1-192 (329) Show / Hide 
Range on Protein: 15-166
Range on HMM: 1-192/329
Sequence Identity: 28% (54 aa)

FDVIDFLGEGSYGKVYRAIDAET----GLEVGLKVINRKALENDKLLYT-------LDREVVALRTA----QNKN-LTNIIRLYS-KTDKND-FTTLILE
. ... ||.||.||||.... .|    .  |  |.| .. . ... ...       |..|.  ...     ..||   ||..||  . ..|.  . .|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YASLGDLSSLIKCYRVLPEDW----------TRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTRG------------GHVRIADFGTSKQL
|   |||...|| .. ||||           ..  .  |. |.  ||. .. ||||||.|||.. |            |.. ||||| .|..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHV
Kinase GL50803_113522.AA ULK 15-166 27 2.3e-32 112.15 In-house 1-188 (324) Show / Hide 
Range on Protein: 15-166
Range on HMM: 1-188/324
Sequence Identity: 27% (53 aa)

FDVIDFLGEGSYG-KVYRAIDAET---GLEVGLKVINRKALENDKLLYT-------LDREVVALRTAQ---NKNLTNIIRLYS-KTDKND-FTTLILEYA
. ... ||.||.| |||.... .|   .  |  |.|..| . ..|....       |..|.  ...     ..|  .|..||  . ..|. .. .|.|| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

SLGDLSSLIKCYRVLPEDW----------TRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTRG------------GHVRIADFGTSKQL
  |||...|| .. |||            ..  .  |. |.  ||. .. ||||||.|||.. |            |.. ||||| .|..
NGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHV
Kinase GL50803_113522.AA PDK1 94-167 48 4.3e-31 92.08 In-house 86-164 (307) Show / Hide 
Range on Protein: 94-167
Range on HMM: 86-164/307
Sequence Identity: 48% (38 aa)

ILEYASLGDLSSLIKC--YRVLPEDWTRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTRGGHVRIADFGTS---KQLP
.|||.. |||....|   .  . .|..||  ||||..|| |||.|  |||.|| ||||.. .|. |.||||.   |.||
VLEYCPNGDLLHYMKKQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILP
Kinase GL50803_113522.AA NDR 101-161 43 4.4e-30 89.47 In-house 86-149 (350) Show / Hide 
Range on Protein: 101-161
Range on HMM: 86-149/350
Sequence Identity: 43% (28 aa)

GDLSS---LIKCYRVLPEDWTRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTRGGHVRIADFG
||. .   |.. .....|||.|| |||... .| .|..||.||||||.|.|. . ||.   |||
GDMMTYCYLLMKMDIFTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG
Kinase GL50803_113522.AA Ciliate-E2 15-166 23 3.3e-25 83.48 In-house 1-206 (365) Show / Hide 
Range on Protein: 15-166
Range on HMM: 1-206/365
Sequence Identity: 23% (50 aa)

FDVIDFLGEGSYGKVYRAIDAETG-----------------------LEVGLKVINRKALENDKLLYTLDREVV----------ALRTAQNKNLTNIIRL
...|  .|.|..|.||.. . ...                        .. .|... . .|. |    . ||.            |.. ...|. ...  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YS-KTDKNDFTTLILEYASLGDLSSLIK-------------------CYRVLPEDWTR-------FLIAEIILGLEGLHSIG-YCHRDIKPSNILLTRGG
.  |.|.| .  |..||.. ||| ..||                     . . .  ..       | ||.|||.|| ||| .  .||||||.|||.    
FQEKDDNNIY--LVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

HVRIADFGTSKQL
 . |.|||.||..
-IKIIDFGLSKKY
Kinase GL50803_113522.AA Ciliate-E2 239-313 35 3.5e-23 76.4 In-house 278-365 (365) Show / Hide 
Range on Protein: 239-313
Range on HMM: 278-365/365
Sequence Identity: 35% (34 aa)

DVWGLGCILYECLTGMPAFMGDVELAIMQAIEKQKVIVP------------------KTVSPDAADLIKR----LLTKDPTKRFNGGWRAIKKHPFF
|.| ||.||||.|.| | |        .| |...|.  |                  | .|... ||||.    .| ||| ||.. ||  |..||.|
DIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT-GWEQILNHPWF
Kinase GL50803_113522.AA PDK1 239-313 39 2.3e-22 64.85 In-house 221-307 (307) Show / Hide 
Range on Protein: 239-313
Range on HMM: 221-307/307
Sequence Identity: 39% (34 aa)

DVWGLGCILYECLTGMPAFMGD-----VELAIMQAIEKQKVIVPKT--VSPDAADLIKRLLTKDPTKRFN-----GGWRAIKKHPFF
| |.||||.| ...| | | |       |. . | | |  .  |    ..|.|.||.|.|| .||..|       ||  .||.||||
DIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQIKAHPFF
Kinase GL50803_113522.AA ULK 239-313 31 4.7e-20 66.76 In-house 238-329 (329) Show / Hide 
Range on Protein: 239-313
Range on HMM: 238-329/329
Sequence Identity: 31% (30 aa)

DVWGLGCILYECLTGMPA----FMGDVELAIMQA----------IEKQKVIVP-----KTVSPDAADLIKRLLTKDPTKRFNGGWRAIKKHPFF
|.| ||||.||.|.| |     |. .... |..           |.||.   |     ...||.  |||.|.|..|...|..  |  . .||.|
DIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRIS--WEELFNHPWF
Kinase GL50803_113522.AA ULK 239-313 31 7.3e-19 63.61 In-house 234-324 (324) Show / Hide 
Range on Protein: 239-313
Range on HMM: 234-324/324
Sequence Identity: 31% (29 aa)

DVWGLGCILYECLTGMPA----FMGDV----ELAIM----QAIEKQKVIVPK------TVSPDAADLIKRLLTKDPTKRFNGGWRAIKKHPFF
|.| ||||.||.|.| .     |. ..    .|  .    | ..|.. | ..       .||.  |||.|.|..|...|..  |  | .||.|
DIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRIS--WEEIFNHPWF
Kinase GL50803_113522.AA NDR 241-313 37 4.3e-18 51.8 In-house 266-350 (350) Show / Hide 
Range on Protein: 241-313
Range on HMM: 266-350/350
Sequence Identity: 37% (32 aa)

WGLGCILYECLTGMPAFMGDVELAIMQAIEKQKVIV-----PKT----VSPDAADLIKRLLTKDPTKRFNG---GWRAIKKHPFF
| ||||.||.|.| | | .|    ... | . | .             .||.|.|||.||.. || .|      |   ||.||||
WSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase GL50803_113522.AA CAMKL 237-313 25 9.3e-12 33.65 In-house 216-297 (297) Show / Hide 
Range on Protein: 237-313
Range on HMM: 216-297/297
Sequence Identity: 25% (22 aa)

PQDVWGLGCILYECLTGMPAFMGD---------VELAIMQAIEKQKVI-VPKTVSPDAADLIKRLLTKDPTKRFNGGWRAIKKHPFF
. |.| .| |||  ..|   | .|         . .   . ..  . . ... || |. |||...|...|.||..     |..||..
KVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPT--IHQIMNHPWM
Kinase GL50803_113522.AA PDK1 15-45 34 6.9e-10 25.94 In-house 1-35 (307) Show / Hide 
Range on Protein: 15-45
Range on HMM: 1-35/307
Sequence Identity: 34% (12 aa)

FDVIDFLGEGSYGKVYRAIDAET----GLEVGLKV
|...  .|||||..||.|.. ||    . .. .|.
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKI
Kinase GL50803_113522.AA TyrKc 15-265 16 2.2e-09 -70.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-265
Range on HMM: 1-280/280
Sequence Identity: 16% (52 aa)

FDVIDFLGEGSYGKVYRAIDAETGLEVGLKVINRKALENDKLLYTLDREVVALRTA--QNKNLTNIIRLYSKTDKN-------DFTTLILEYASLGDLSS
   .. |||| .|.||...     ..|  |...  |      .  . ||   ..    ...   ||.|||    .        .   ...||...||| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHP---NIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LIKCYRV-LPEDWTRFLIAEIILGLEGLHSIGYCHRDIKPSNILLTRGGHVRIADFGTSKQLPLD------EVSMAI----GTK-----------SF---
 .. .|  |. .        |  | | ||| .. |||.   |.|......|.|.||| |. .  |      .         |.|           ..   
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

-----------------------PPSAY-----MSTSSAAASNDSQGTLQKKLQNMDQQPRCSIYGTVCYNAPESNRHGLLYMSPQDVWGLGCILYECLT
                       .|        || . . .  .. . . .   .    |  |                    ..     .  |  .|  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---P-MS--------------------FVCCPDEMYQIMKQCWH

GMPAF---MGDVELAI
  |.    . ..   .
EDPEDRPTFSEIHECF
Kinase GL50803_113522.AA NDR 15-30 37 0.000824 6.91 In-house 1-16 (350) Show / Hide 
Range on Protein: 15-30
Range on HMM: 1-16/350
Sequence Identity: 37% (6 aa)

FDVIDFLGEGSYGKVY
|..|  .|.|..|.|.
FEIIKIIGKGAFGEVW
PDK1_PH GL50803_113522.AA PDK1_PH 372-435 44 4.3e-20 69.43 In-house 1-68 (112) Show / Hide 
Range on Protein: 372-435
Range on HMM: 1-68/112
Sequence Identity: 44% (30 aa)

SPLRRFLI-PGENIIYSIDVVKRRVLRL---PKQRRFVLTDFPRLFYIDVSTMVQKGEIDMTSTNLKI
.| ..||  .||.|..  .| ||. |      | |...|||.|||||.|..|||.||||. .| .|..
TPWHQFLMPEGEHILKCGWVYKRKGLFAKPKKKRRQLILTDGPRLFYVDPMTMVIKGEIPWSSKDLYV