Gene GL50803_11554 (G.lamblia)

GL50803_11554

Species: G.lamblia
Alias: GK249, GL50803_11554
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_11554.AA Protein None 273 None Fasta, JSON
GL50803_11554.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of GL50803_11554.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_11554.AA S_TKc 9-262 24 8.5e-28 99.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-231/231
Sequence Identity: 24% (65 aa)

YRDVSVIGRGCHGRVYKAFRRDTGAVVAVRDVDLRRFDAAAVRHLFEQEKAEVRLVH---PFIVQNHSMTKSREEFSLHIEMEYCAD--GSLDDLRWERK
|. . .||.|  |.|||.  ..|| .||.  ..             |. . |... .   |.||. . .  .    .|.. ||||    |.| |.  .|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKKHHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRG

M--SHCYIPEYRIWEIIVQVAGALVYMHDPNKPGGIVLHKNLKLSNILANGHAVKIGDVGLPEIDYTKRPDYHVFEAYRAPEATKFGIYDT-ASDIWSFG
    ....|| ... .. |.. || |.|. .     ..|  || .||| .   .||.| ||  .       . .   |.|||      |.. ..|.||.|
RHGLRFPFPE-HARFYMYQICCALEYCHSHG-----IIHRDLKPENILLDE-HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VLLLELCTFKQPNWKPSLLKVAPQYELWEEYSDDLYYLIEDCLKLKASERLTAGDIYL-------HPQA
..| |... . | .      ..  ...    |...  .|. ||.   ..|.|| ..         ||  
CILYEMLCGYPPFP-----QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase GL50803_11554.AA Pkinase 9-262 21 3.3e-23 83.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-293/293
Sequence Identity: 21% (67 aa)

YRDVSVIGRGCHGRVYKAFRRDTGAVVAVRDVDLRRFDAAAVRHLFE-QEKAEVRLV-HPFIVQNHSMTKSREEFSLHIEMEYCADG----SLD----DL
|. ...||.|  |.|||. ...|| .|||  ...|. .    ....  .| .  . . ||.||. . .  .  . .... ||||  |    .|       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

RWERKMSHCYI--PEYRIWEIIVQVAGALVYMHDPNKPGGIVLHKNLKLSNILAN--GHA---VKIGDVGLP----EIDYTKRPDYHVFEAYRAPEATK-
     ..|. .  .|  .  .. |.. .| |.|. .     ..|  ||..||| .  ||    |||.| ||     .  ..   .. .   |.|||  . 
-----WRHGCFYFSEWECKFYMYQILRGLEYCHS-M----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

FGIYDTASDIWSFGVLLLELCTFKQPNWKP-------------SLLKVAPQYELWEEYS-------------------DDLYYLIEDCLKLKASERLTAG
   |....|.||.|..| |... . | .                 ..  . .. ....|                   ...  .|..||... ..|.|| 
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

DIYLHPQA
.|  ||  
QILQHPWF
Kinase GL50803_11554.AA TKL 15-260 17 1.9e-19 66.7 In-house 1-364 (364) Show / Hide 
Range on Protein: 15-260
Range on HMM: 1-364/364
Sequence Identity: 17% (66 aa)

IGRGCHGRVYKAFRRD--------TGAVVAVRDVDLRRFDAAAV---------------------RHLFEQEKAEVRL---V-HPFIVQNHSMTKSREEF
||.|  | |||.  |         || .|||     .  |                         ......|. |...     || |||     .. .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

S-----------LHIEMEYCADGS-LDDLRWERKMSHCYIPEYRIWEIIVQVAGALVYMHD--P--NKPGGI--VLHKNLKLSNILANGHA---------
            |.| ||||  || |..|              ..  .. ..| .. |.|   |   .      ..| .|| .||| . .          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT---KPPIIHRDLKSKNILVDENWTNVSNYMYN

------VKIGDVG----LPEIDYTKRPDYHVFE------------------AYRAPEATK----------------FGIYDTASDIWSFGVLLLELCT--
      .||.| |    . .    ..  ... |                  .. |||. .                .. |....|..|||..| |..|  
PNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRC

--FKQPNWKPSLLKVAPQYELWEEY-----------------------SDD---LYYLIEDCLKLKASERLTAGDIYLHP
  .....  | ..   | .|.. ..                       .|    .  |..|| . ....|... .|  . 
RPYYDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase GL50803_11554.AA Ciliate-E2-Unclassified 9-212 20 2.1e-19 63.95 In-house 1-269 (352) Show / Hide 
Range on Protein: 9-212
Range on HMM: 1-269/352
Sequence Identity: 20% (56 aa)

YRDVSVIGRGCHGRVYKAFRRDTGAVV-------AVRDVDLRRFDAAAVRHLFEQEKAEVR------------------LVHPFIVQNHSMTKSREEFSL
|. . .||.|..| |||. .....  .        ..... .       ....|..  . .                  . |||||  . . ....   .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQN--I

HIEMEYCADGSLDD---LRWE----------RKMSHCYIPEYRIW-----EIIVQVAGALVYMHDPNKPGGIVLHKNLKLSNILA-NGH---AVKIGDVG
 | |||| .|.| .    |.           .... . ..|. .       .. |.  .| |.|  |.    ..| ..|..|||  |..    .|| | |
YIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNN----IIHRDIKPENILFDNNGKNYYIKIIDFG

L----------------------PEIDYTKR--PDYHVFEAYRAPEATKFGIYD----TASDIWSFGVLLLELCTFKQP
.                      ... .|.   | |   . | |||  .   ||     ..||||.||.| |... . |
ISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMP-Q-YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase GL50803_11554.AA Ciliate-E2 9-260 19 4.7e-19 62.03 In-house 1-363 (365) Show / Hide 
Range on Protein: 9-260
Range on HMM: 1-363/365
Sequence Identity: 19% (74 aa)

YRDVSVIGRGCHGRVYKAFRRDTGAVVAVR-------------DVDLRRFDAAAVRHL-FEQEKAEVRLV--------------------HPFIVQNHSM
|  . .||.|..| |||. .. ..  .| .              |.   .    ...   || | | ..                     ||.|.. .  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TKSREEFSLHIEMEYCADGSLDD-LRWERKMSHCYIP------EYRIWEIIVQVAG---------------ALVYMHDPNKPGGIVLHKNLKLSNILANG
 ..  . .. . ||||  |.| | ..  .| ... |.      |. | .|. |..                || |.|  |.    ..| ..|..|||   
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN----IIHRDIKPENILF--

HAVKIGDVGL------PEIDYT------KRPDYHV-----------------------FEAYRAPEATK---------FGIYDTASDIWSFGVLLLELCT
  .|| | ||      .....|      . .. ..                          | |||  .         .  ||...||||.||.| |...
--IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

FKQPNWKPSLLKVA------PQYE-------------LWEEYSDDLYYLIED----CLKLKASERLT-AGDIYLHP
 | |     . .        |..|              |.. |..   ||      .|. . ..|.| . .|  ||
GKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHP
Kinase GL50803_11554.AA TK 9-209 15 8.8e-14 41.83 In-house 1-390 (486) Show / Hide 
Range on Protein: 9-209
Range on HMM: 1-390/486
Sequence Identity: 15% (62 aa)

YRDVSVIGRGCHG---RVYKAFRRD-----------------------TGAVVAVRDVDLRRFDAAAVRHLFE-------------QEKAEVRLV-----
 . . ..|.|  |   .|||.  |.                       .|... |    |.  ||.. .  |.             .| .|  .      
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HPFIVQNHS-MTKSRE---------EFSLHIEMEYCADGS----LDDLRWERK--------------------------------MSHCYIPEYRIWE-
 || ||. .   |....         .  . | |||.. |.    |.|  ....                                 ...  |.    . 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPC-PEEQD

---------------------------------------IIVQVAGALVYMHDPN-KPGGI--VLHKNLKLSNILANGHA------------VKIGDVGL
                                       . .|.| .. |.|. | . . |  . | .|   |.| . .             .||.| ||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-F-IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL

PE-------IDYTKRPDYHVFEAYR------------------------------APEATK---------FGIYDTASDIWSFGVLLLELCTF
          |  .. ||.. . |.                              |||. .         .|.. |.||.||||||. |..|.
SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTY
Kinase GL50803_11554.AA STE 9-159 22 1e-13 44.89 In-house 1-190 (359) Show / Hide 
Range on Protein: 9-159
Range on HMM: 1-190/359
Sequence Identity: 22% (44 aa)

YRDVSVIGRGCHGRVYKAFRR------DTGAV---------VAVRDVDLRRFDA---------------AAVRHLFEQEKAEVRLV--HPFIVQNHSMTK
......||.|  | |||| ..      .|| |         .|.  ..|.. ..                 .  . .  |   ..   ||.||. . .  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----SREEFSLHIEMEYCADGSLDDLRWERKMSHC----------YIPEYRIWEIIVQVAGA-LVYMHDPNKPGGIVLHKNLKLSNILANGHAVKIGD
     . .. .|.| |||.. |||||.  ....  .          ..||  |  |..|.  . | | |. .     . |  .| .|||     ||. |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-----IIHRDIKPANILL----VKLCD
Kinase GL50803_11554.AA TyrKc 9-266 21 9.2e-13 -16.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-266
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

YRDVSVIGRGCHGRVYKAFRRDTGAVVAV---RDVDLRRFDAAAVRHLFEQEKAEVRLV---HPFIVQNHSMTKSREE-----FSLHIEMEYCADGSLDD
 .   ..|.|. |.|||.  .     |||   ..           |  | .|    . .   || ||. .    . ..       | | |||.. |.|.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LRWERKMSHCYIPEYRIWEIIVQVAGALVYMHDPNKPGGIVLHKNLKLSNIL-ANGHAVKIGDVGLPEIDYTK-----RPDYHVFE---AYR--------
   ...     ..     .. .|.|    | |.       . |  |   |.| ...| |||.| ||    | .     . || .       .        
YLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK-----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APEATKFGIYDTASDIWSFGVLLLELCTF-KQPNWK-----PSLLKVAPQYELW-----EEY---------SDDLYYLIEDCLKLKASERLTAGDIYLHP
|||. ..|.. |.||.|||||.. |..|. .|| .       |   |  . .        ..         .|..| ....| . ....| |  .|    
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----

QAQEAL
   | .
--HECF
Kinase GL50803_11554.AA CAMK 14-162 15 4.6e-12 34.44 In-house 1-242 (425) Show / Hide 
Range on Protein: 14-162
Range on HMM: 1-242/425
Sequence Identity: 15% (38 aa)

VIGRGCHGRVYKAFRRDTG------------AVVAVRDVDLRRFD-------------------------AAAVRHLFEQEKAEVRLV--------HPFI
..|||  | |...... |.              ||.  .| .. .                          .  |. ...| .  ...        || |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQNHSMTKSREEFS-----------------LHIEM---EYCADGSL-DD-LRWERKMSH-------------CYIPEYRIWEIIVQVAGALVYMHDPNK
.. . .  ... |.                 ... |   |||  | | || . . .. ..              ...|     .. |.. |. |.|.   
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS---

PGGIVLHKNLKLSNILANGH-----------------A-VKIGDVGL
  . . |  ||. ||| . .                 . .|| | |.
-HN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGF
Kinase GL50803_11554.AA WEE 82-162 23 4.6e-12 36.83 In-house 79-178 (297) Show / Hide 
Range on Protein: 82-162
Range on HMM: 79-178/297
Sequence Identity: 23% (25 aa)

SLHIEMEYCADGS--LDDLRWERKMSHCYIPEYRIWEIIVQVAGALVYMHDP-NKPGGIVLHKNLKLSNILANGH---------------------AVKI
...| ||||  ||  | ..  . . .  ..||..|| |.|... .| ..|.  .      .|  .| .||. . .                       ||
HMYIQMEYCNGGSNLLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCG-----MVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKI

GDVGL
|| |.
GDFGH
Kinase GL50803_11554.AA RIPK 15-162 25 2.1e-11 35.07 In-house 1-155 (290) Show / Hide 
Range on Protein: 15-162
Range on HMM: 1-155/290
Sequence Identity: 25% (42 aa)

IGRGCHGRVYKAFRRDTGAVVAVRDVDLRRFDAA----AVRHLFEQEKAEVRLVHPFIVQNHSMTKSREE---FS-LHIEMEYCADGSLDDLRWERKMSH
.|.|  | |.||. |. | .||.  .     ...     . ...|. |.. .| . .||.   ...  |       . | ||| . ||| ...     ..
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFL----HTK

C-YIPEYRIWE----IIVQVAGALVYMHDPNKPGGIVLHKNLKLSNILANGH-AVKIGDVGL
. | .  . |     .|.... .  | |. | |   ..|. ||..|||  ..  ||| | ||
WPYQHHPDPWPLRCRMIHEISCGMCYLHSMNPP---IIHRDLKPENILVDNNFHVKIADFGL
Kinase GL50803_11554.AA NEK2 9-148 25 1.6e-10 31.55 In-house 1-156 (319) Show / Hide 
Range on Protein: 9-148
Range on HMM: 1-156/319
Sequence Identity: 25% (41 aa)

YRDVSVIGRGCHGRVYKAFRRDTGAVVAVRDVDLRRFDAAAVRHLFEQEKAEV----RLVHPFIVQNHSMTKSREEFSLHIEMEYCADGSLDDLRWERKM
|    .||.|  ||..|  |  .| . .  . .    . .    |     .|.     | ||.||.       |.. .| | ||||. | |  .    . 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLV----SECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRK

SHCYIPEYRIWEIIVQVAGALVYMHD---------------PNKPG-GIVLHKNLKLSNI
 . |..|  || |  |   ||   |                | ..| ...||  .|  ||
ERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANI
Kinase GL50803_11554.AA Pkinase_Tyr 181-209 51 9.1e-10 33.7 Pfam 182-210 (270) Show / Hide 
Range on Protein: 181-209
Range on HMM: 182-210/270
Sequence Identity: 51% (15 aa)

APEATKFGIYDTASDIWSFGVLLLELCTF
|||. ..|.. |.||.||||||. |..|.
APECINYGKFTTKSDVWSFGVLMWEIFTY
Kinase GL50803_11554.AA NEK 82-130 37 1.6e-07 22.95 In-house 80-132 (286) Show / Hide 
Range on Protein: 82-130
Range on HMM: 80-132/286
Sequence Identity: 37% (20 aa)

SLHIEMEYCA-DGSLDDL---RWERKMSHCYIPEYRIWEIIVQVAGALVYMHD
.|.|.||||   | |...     ..| .. |..|  ||.. .| . || ||||
CLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHD
Kinase GL50803_11554.AA STE 190-262 19 2e-06 18.99 In-house 245-359 (359) Show / Hide 
Range on Protein: 190-262
Range on HMM: 245-359/359
Sequence Identity: 19% (22 aa)

YDTASDIWSFGVLLLELCTFKQPN---WKPSLL--------------------KVAPQYELW-----------------EEYSDDLYYLIEDCLKLKASE
||| .||||.| ...|..| | |      .. .                    .  |. .                   ...|...   |. ||.   ..
YDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNK

RLTAGDIYL--HPQA
| || .     ||  
RPTASQLLKSEHPFI
Kinase GL50803_11554.AA NEK 190-212 52 3e-06 18.38 In-house 201-225 (286) Show / Hide 
Range on Protein: 190-212
Range on HMM: 201-225/286
Sequence Identity: 52% (13 aa)

YDTASDIWSFGVLLLELCTF--KQP
|.  |||||.|..| |.||.  | |
YNNKSDIWSLGCVLYEMCTLKPKHP
Kinase GL50803_11554.AA CAMK 190-260 16 2.5e-05 12.35 In-house 311-423 (425) Show / Hide 
Range on Protein: 190-260
Range on HMM: 311-423/425
Sequence Identity: 16% (19 aa)

YDTASDIWSFGVLLLELCTFKQPNWKP--------------------SLLKVAPQYEL--------------WEEYSDD--------LYYLIEDCLKLKA
|. ..|.|| ||.|  . . . | . .                      .|   ...               | . ||.           ||  .|.   
YGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDP

SERLTAGDIYLHP
..|.|. ..  ||
EKRMTIEQCLNHP
Kinase GL50803_11554.AA NEK2 190-208 52 0.000476 9.39 In-house 241-259 (319) Show / Hide 
Range on Protein: 190-208
Range on HMM: 241-259/319
Sequence Identity: 52% (10 aa)

YDTASDIWSFGVLLLELCT
|.  ||||| | |. |.|.
YNEKSDIWSVGCLIYEMCA
Kinase GL50803_11554.AA NEK 9-44 24 0.00101 9.44 In-house 1-41 (286) Show / Hide 
Range on Protein: 9-44
Range on HMM: 1-41/286
Sequence Identity: 24% (10 aa)

YRDVSVIGRGCHGRVYKAFRRDTGAV-----VAVRDVDLRR
|. . .||.| .|.|||. |. .| .     ..   ... .
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGN
Kinase GL50803_11554.AA RIPK 177-212 25 0.011503 4.87 In-house 192-227 (290) Show / Hide 
Range on Protein: 177-212
Range on HMM: 192-227/290
Sequence Identity: 25% (9 aa)

EAYRAPEATKFGIYDTASDIWSFGVLLLELCTFKQP
|..|  ..    . ....|. ||.... |. | |.|
EHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase GL50803_11554.AA WEE 9-32 41 0.017498 4.23 In-house 1-24 (297) Show / Hide 
Range on Protein: 9-32
Range on HMM: 1-24/297
Sequence Identity: 41% (10 aa)

YRDVSVIGRGCHGRVYKAFRRDTG
.  |..||.|  | |||.  | .|
FQEVQKIGEGSFGEVYKCRCRIDG
Kinase GL50803_11554.AA NEK 231-262 31 0.063221 3.04 In-house 255-286 (286) Show / Hide 
Range on Protein: 231-262
Range on HMM: 255-286/286
Sequence Identity: 31% (10 aa)

YSDDLYYLIEDCLKLKASERLTAGDIYLHPQA
||.||  ||. .|.   ..| .. .|  .|. 
YSQDLQNLISQMLQKDPEQRPSCNQILEMPFI