GL50803_11775

Species: G.lamblia
Alias: GL50803_11775, GK301
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_11775.AA Protein None 1618 None Fasta, JSON
GL50803_11775.kin_dom Protein Kinase Domain None 283 None Fasta, JSON

Protein domain

Protein domains of GL50803_11775.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_11775.AA S_TKc 6-288 12 1.4e-08 -51.15 SMART 1-231 (231) Show / Hide
Range on Protein: 6-288
Range on HMM: 1-231/231
Sequence Identity: 12% (40 aa)

YTLISQVSATENCKTMLVQHNG-TGNYAFKYFYTSWPVPNARLRSCMDAYLQLTCPHIIRLQTYSIDTAFTLVTDMTNG--PSLRSLIIKRRI--AQQWF
|... ..      | ....|..    .| |           ..|. ..   .  .|.|..|  .  |. . .|... .|   .|...| ||.    ...|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

TSVEIWLLITQLLEGVKAYQSF------------------------YARVGAAADTPPNLFLSPFFILISDEERMKLQITEFYQTLLLPSVQRLYATSGV
.  ... .. |......   |                          ||.                                           .  |   
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL----------------------------------------TTFCGTPWY

APPEVSKHLPISA-SADIWMIGAILYELLT----LQQLDLDRLIELNSDVVTLAKIDNLYPIDYEPLEPYQSVAVYSFLDHGKAFRYRELYSLLSCMLII
 .|||    . .  ..|.| .| ||||.|.     .  ........                                         .|. .... .|  
MAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------------------------------SPEAKDFIRKCLQK

NPDKRPPVELLLD-------YALL
.|.||| .  .|           .
DPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_11775.AA RSKL 179-205 44 4e-06 8.99 In-house 347-373 (436) Show / Hide
Range on Protein: 179-205
Range on HMM: 347-373/436
Sequence Identity: 44% (12 aa)

PEVSKHLPISASADIWMIGAILYELLT
|||.   .     |.|  ||.|||||.
PEVGQIWELTEACDWWSYGAVLYELLC

Kinase GL50803_11775.AA Ciliate-D1 192-210 52 2.8e-05 18.47 In-house 1-19 (19) Show / Hide
Range on Protein: 192-210
Range on HMM: 1-19/19
Sequence Identity: 52% (10 aa)

DIWMIGAILYELLTLQQLD
||| .| ||||.|. |. .
DIWSFGCILYEMLFGQPPF

Kinase GL50803_11775.AA DRAK 179-205 40 0.000146 9.47 In-house 170-196 (259) Show / Hide
Range on Protein: 179-205
Range on HMM: 170-196/259
Sequence Identity: 40% (11 aa)

PEVSKHLPISASADIWMIGAILYELLT
||. .  ||. . |.| || . | .||
PEILNYDPITMATDMWSIGVLTYVMLT

Kinase GL50803_11775.AA NEK10 179-207 41 0.000164 10.53 In-house 189-217 (279) Show / Hide
Range on Protein: 179-207
Range on HMM: 189-217/279
Sequence Identity: 41% (12 aa)

PEVSKHLPISASADIWMIGAILYELLTLQ
||. . .|    ||.| .| .||.. |||
PEIVQSEPYGEKADVWAFGCCLYQMCTLQ

Kinase GL50803_11775.AA MLK 179-205 36 0.000202 11.4 In-house 202-231 (291) Show / Hide
Range on Protein: 179-205
Range on HMM: 202-231/291
Sequence Identity: 36% (11 aa)

PEV---SKHLPISASADIWMIGAILYELLT
|||   ... . | ..|.| .| .|.|.||
PEVIQQFRCEKYSEKCDVWSWGVVLWEMLT

Kinase GL50803_11775.AA NEK2 259-288 23 0.00047 9.41 In-house 290-319 (319) Show / Hide
Range on Protein: 259-288
Range on HMM: 290-319/319
Sequence Identity: 23% (7 aa)

RELYSLLSCMLIINPDKRPPVELLLDYALL
|.|  . . |. ... .|| .| .| . ..
RHLNEIIHFMINVDHYHRPSIEEILQHPQI

Kinase GL50803_11775.AA NEK 179-207 44 0.00054 10.41 In-house 193-221 (286) Show / Hide
Range on Protein: 179-207
Range on HMM: 193-221/286
Sequence Identity: 44% (13 aa)

PEVSKHLPISASADIWMIGAILYELLTLQ
||| .. | .  .|||..| .|||. ||.
PEVCQNKPYNNKSDIWSLGCVLYEMCTLK

Kinase GL50803_11775.AA MSK 177-205 29 0.000723 8.95 In-house 172-205 (277) Show / Hide
Range on Protein: 177-205
Range on HMM: 172-205/277
Sequence Identity: 29% (10 aa)

APPEVSK----HLP-ISASADIWMIGAILYELLT
..||. .    . .  ... |.|  |.|||..||
MAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLT

Kinase GL50803_11775.AA NEK8 260-288 24 0.000788 6.68 In-house 250-278 (278) Show / Hide
Range on Protein: 260-288
Range on HMM: 250-278/278
Sequence Identity: 24% (7 aa)

ELYSLLSCMLIINPDKRPPVELLLDYALL
|. .| .  |   |..||..  .... |.
EMRMLVHNCLQQDPEQRPSASQIMAMPLC

Kinase GL50803_11775.AA NEK8 192-206 46 0.001099 6.26 In-house 204-218 (278) Show / Hide
Range on Protein: 192-206
Range on HMM: 204-218/278
Sequence Identity: 46% (7 aa)

DIWMIGAILYELLTL
|.| .| .|||...|
DMWALGCVLYEMCCL

Kinase GL50803_11775.AA NEK1 259-288 40 0.002297 7.73 In-house 247-276 (276) Show / Hide
Range on Protein: 259-288
Range on HMM: 247-276/276
Sequence Identity: 40% (12 aa)

RELYSLLSCMLIINPDKRPPVELLLDYALL
.|| ||.| |. .||  || |  .|    .
YELQSLVSQMFKRNPRHRPSVNQILERPFI

Kinase GL50803_11775.AA NEK1 192-206 66 0.002688 7.49 In-house 203-217 (276) Show / Hide
Range on Protein: 192-206
Range on HMM: 203-217/276
Sequence Identity: 66% (10 aa)

DIWMIGAILYELLTL
|||  | .||||.||
DIWSLGCVLYELCTL

Kinase GL50803_11775.AA NEK 259-288 30 0.004325 7.19 In-house 257-286 (286) Show / Hide
Range on Protein: 259-288
Range on HMM: 257-286/286
Sequence Identity: 30% (9 aa)

RELYSLLSCMLIINPDKRPPVELLLDYALL
..| .|.| ||  .|..|| .. .|   ..
QDLQNLISQMLQKDPEQRPSCNQILEMPFI

Kinase GL50803_11775.AA NEK2 179-206 32 0.109212 1.32 In-house 233-260 (319) Show / Hide
Range on Protein: 179-206
Range on HMM: 233-260/319
Sequence Identity: 32% (9 aa)

PEVSKHLPISASADIWMIGAILYELLTL
||. . .. .   ||| .| ..||. .|
PEQMHGQKYNEKSDIWSVGCLIYEMCAL

Ank GL50803_11775.AA Ank 374-394 38 0.009695 14.14 Pfam 1-21 (33) Show / Hide
Range on Protein: 374-394
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

DGNTALVYAIKANNEDAVKIL
||.|.| .|.. .... || |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_11775.AA Ank 405-425 42 0.005564 15.01 Pfam 1-21 (33) Show / Hide
Range on Protein: 405-425
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

EGYSPLHLALLLNHIQLAKYL
.|..||||| . .|.. .|.|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_11775.AA Ank 475-506 18 1.35694 6.4 Pfam 1-21 (33) Show / Hide
Range on Protein: 475-506
Range on HMM: 1-21/33
Sequence Identity: 18% (6 aa)

DGKTALIKAVLNYNEGLPAGQEDVNLAIIRLL
|| |.|  |...            .. ....|
DGFTPLHLACRCG-----------HTEVVKML

Ank GL50803_11775.AA Ank 517-537 33 0.007607 14.52 Pfam 1-21 (33) Show / Hide
Range on Protein: 517-537
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

RGRTALMYAAECGYLAAIDVL
 |.|.|..|..||..  .  |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_11775.AA Ank 612-629 22 0.403439 8.3 Pfam 1-18 (33) Show / Hide
Range on Protein: 612-629
Range on HMM: 1-18/33
Sequence Identity: 22% (4 aa)

NGNTALMHCVIHDRPEFI
.|.|.|.  ......| .
DGFTPLHLACRCGHTEVV

Ank GL50803_11775.AA Ank 643-666 20 6.279172 4.0 Pfam 1-24 (33) Show / Hide
Range on Protein: 643-666
Range on HMM: 1-24/33
Sequence Identity: 20% (5 aa)

TGHSAMMLAVQLERRACFEALIKH
 | .. .||..  .  . . |..|
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_11775.AA Ank 674-706 21 2.081199 5.73 Pfam 1-33 (33) Show / Hide
Range on Protein: 674-706
Range on HMM: 1-33/33
Sequence Identity: 21% (7 aa)

SGMTALMMCASQGLRPYVNRLLNIETNIFNGTW
 |.|.|.. .. |    |  ||.   ..   . 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_11775.AA Ank 767-784 33 0.248348 9.06 Pfam 1-18 (33) Show / Hide
Range on Protein: 767-784
Range on HMM: 1-18/33
Sequence Identity: 33% (6 aa)

SGYTPLMFAAQQANINAV
 |.|||. |..  ... |
DGFTPLHLACRCGHTEVV

Ank GL50803_11775.AA Ank 798-820 34 0.014221 13.54 Pfam 1-23 (33) Show / Hide
Range on Protein: 798-820
Range on HMM: 1-23/33
Sequence Identity: 34% (8 aa)

HGFTALIYATRVKSLECCRLLVD
.|||.| .| |  ..|....|..
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_11775.AA Ank 981-992 41 0.992449 6.89 Pfam 1-12 (33) Show / Hide
Range on Protein: 981-992
Range on HMM: 1-12/33
Sequence Identity: 41% (5 aa)

SGETALMLAAKS
 |.|.|.||...
DGFTPLHLACRC

Ank GL50803_11775.AA Ank 1077-1109 24 58.157131 0.51 Pfam 1-33 (33) Show / Hide
Range on Protein: 1077-1109
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

SAYTALNICIYCGKNTLIPLFLPYEADIEIHDK
  .|.| . ..||    . ..| . ||. ..|.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_11775.AA Ank 1249-1281 36 1.1e-05 24.81 Pfam 1-33 (33) Show / Hide
Range on Protein: 1249-1281
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

KGETALMLAARSGSEAVVDILLNYEAEMQDNNK
 |.|.|.||.|.|.. ||  ||.. |.    ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_11775.AA Ank 1312-1330 31 2.72115 5.31 Pfam 1-19 (33) Show / Hide
Range on Protein: 1312-1330
Range on HMM: 1-19/33
Sequence Identity: 31% (6 aa)

CELSPLMLAVLEGDIKTVS
.  .||.||.. |... |.
DGFTPLHLACRCGHTEVVK

Ank GL50803_11775.AA Ank 1342-1364 34 3.424163 4.95 Pfam 1-20 (33) Show / Hide
Range on Protein: 1342-1364
Range on HMM: 1-20/33
Sequence Identity: 34% (8 aa)

SGMTALHMAIYLRQQAHANLLKM
 |.|.||.|..     |.. .||
DGFTPLHLACRCG---HTEVVKM

Ank GL50803_11775.AA Ank 1399-1417 31 12.751064 2.89 Pfam 1-19 (33) Show / Hide
Range on Protein: 1399-1417
Range on HMM: 1-19/33
Sequence Identity: 31% (6 aa)

LGCTELHRAAIQNNSQQVR
 |.| || |.. .. . |.
DGFTPLHLACRCGHTEVVK

Ank GL50803_11775.AA Ank 1429-1461 27 0.00267 16.16 Pfam 1-33 (33) Show / Hide
Range on Protein: 1429-1461
Range on HMM: 1-33/33
Sequence Identity: 27% (9 aa)

NGRTSLMEAALAGSLDAAKILVDHEHGMRARAR
.|.| |. |.. |... .| |..|     |. .
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_11775.AA Ank 1470-1491 36 0.000925 17.82 Pfam 1-22 (33) Show / Hide
Range on Protein: 1470-1491
Range on HMM: 1-22/33
Sequence Identity: 36% (8 aa)

DEATALMFAAAAGHESIVRLLI
|  |.|. |.  ||...|..|.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_11775.AA Ank 1502-1524 34 0.000364 19.28 Pfam 1-23 (33) Show / Hide
Range on Protein: 1502-1524
Range on HMM: 1-23/33
Sequence Identity: 34% (8 aa)

NGKTALMAAAAAGHLSTLKLLID
.| |.|. |.  ||.. .|.|..
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_11775.AA Ank 1533-1558 26 0.088287 10.68 Pfam 1-26 (33) Show / Hide
Range on Protein: 1533-1558
Range on HMM: 1-26/33
Sequence Identity: 26% (7 aa)

NGWTALMSVVSKQYVDCVAPLLEKEA
.|.|.|.  ... ....|  ||.. |
DGFTPLHLACRCGHTEVVKMLLQHGA

Ank GL50803_11775.AA Ank 1564-1584 28 1.142098 6.67 Pfam 1-21 (33) Show / Hide
Range on Protein: 1564-1584
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

QGNCALVTAISNGNMDIVRVL
 |. .|  |...|....|. |
DGFTPLHLACRCGHTEVVKML