Gene GL50803_14216 (G.lamblia)

GL50803_14216

Species: G.lamblia
Alias: GK183, GL50803_14216
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_14216.AA Protein None 774 None Fasta, JSON
GL50803_14216.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of GL50803_14216.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_14216.AA S_TKc 9-262 36 7.3e-75 255.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

YDSPEYIDSGSFGKVYRAYSKDTGELVAVKEIDLYYLTDNLLDKIEQEFSTAQKLDHPNILKYKTIRKDEYYYLLEMELCDQ---SLEDVIRSQRY--LG
|.  . | .|.|||||... |.||..||.|.|.         ..|..| .  .| .|||| |.. .  |  .. . ||.||.   .| |.|.....  |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

YPFQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFTDTHIKLGDFGLARETSGKSRMTTCTGTPVYMAPEVQRGDFYGT-AADIWSLGCII
.|| |  ..... ||...|.|.||.      |.|||||| |||... |||..||||||.       ||. ||| ||||||     ||. ..|.||.|||.
FPFPE-HARFYMYQICCALEYCHSHG-----IIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LEICTLKPIPWSTEHLKDNPQITIDTTYYSEDLATLIRSCLQLDSNARPTAEEILS-------HPQV
 | ..    |..      ..| ...    |...  .|| ||| | . |||| |.|        || .
YEMLC-GYPPFP------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_14216.AA Pkinase 17-262 32 6.5e-69 240.05 Pfam 9-293 (293) Show / Hide 
Range on Protein: 17-262
Range on HMM: 9-293/293
Sequence Identity: 32% (96 aa)

SGSFGKVYRAYSKDTGELVAVKEIDLYYLTDNLLDKIEQ--EFSTAQKLDHPNILKYKTIRKDEYYYLLEMELCDQSLEDVIRSQRYLG-------YPFQ
|||||.||... |.||..||||.|..    .. .       | .  ..|.||||.... .  |. .. . ||.|.  |. |.   .|.        | |.
SGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFY-FS

EPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFT-DTHI----KLGDFGLARE--TSGKSRMTTCTGTPVYMAPEVQR-GDFYGTAADIWSLG
|  .  .. ||. ||.|.||.      |.|||||| |||.  . ||    |..|||||.   .  .| ||| .||| |||||| | |  ||...|.||.|
EWECKFYMYQILRGLEYCHSM-----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

CIILEICTLKPIPWST------EHLKDNPQITIDTTYYS-------------------------EDLATLIRSCLQLDSNARPTAEEILSHPQV
||. | .. .|. ..       ....   .|    . ..                         |..  .|..||..| . |||||.|| || .
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_14216.AA STE 9-262 25 7.5e-64 218.45 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-359/359
Sequence Identity: 25% (96 aa)

YDSPEYIDSGSFGKVYRAYSKD---------------TGELVAVKEIDLYYLT---------------DNLLDKIEQEFSTAQKLD--HPNILKYKTIRK
..  | | .|.||.||.|. ..               |||..|.|...|   .               .. ...|..| .. .|..  |||| ||     
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DEY-------YYLLEMELCD-QSLEDVIR-SQRYLG---------YPFQEPYIWYVIGQIVNG-LAYMHSQSITSSTIVHRDLKPGNILFTDTHIKLGDF
.|        .  . ||..|  ||.|.|.     ..          .|.|. | |.. ||. | |.| ||.      |.|||.||.|||.    .|| ||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-----IIHRDIKPANILL----VKLCDF

GLARETSG-----------------KSRMTTCTGTPVYMAPEVQRG------DFYGTAADIWSLGCIILEICTLKPIPWST-EHL---------------
|..   .                  ... .|..||| .||||| ..      . |.| .||||||| |.| .| || ||..  ..               
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKP-PWHDMHPMRAMFMIPFNYHMQQQ

--------KDNPQITID----------------TTYYSEDLATLIRSCLQLDSNARPTAEEILS--HPQV
        .. |..  .                .. .|...   |. ||| | | ||||.. |.  || .
FEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_14216.AA ULK 9-262 25 6.5e-56 192.07 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-329/329
Sequence Identity: 25% (86 aa)

YDSPEYIDSGSFGKVYRAYSKDT----GELVAVKEIDLYYLTDNLLD--------KIEQEFSTAQKLD--------HPNILKYKTIRKDE--YYYLLEME
|   . . .|||||||... |.|    .|.||.| ||. ..  .. .         ...|  . .||.        |||| |.. . ..    .. . ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCDQ-SLEDVIRSQRYLG------YPFQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFTDT-------------HIKLGDFGLARE-TSG
.|..  ||. |  ...|.        . |. .  .. ||.||. ..|..      |.|||.|| ||| ..              ..|..|||.|.  ...
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHN-----IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDND

---KSRMTTCT------GTPVYMAPEVQRGD-----FYGTAADIWSLGCIILEICTLK--PIPWSTEHLK-----DNPQI---------TIDTTYY----
   .  |.||.      ||| ||||..  |      .|   .||||||||. |. . |  .  |  . ..     .. ..         .. . ..    
NMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN

----SEDLATLIRSCLQLDSNARPTAEEILSHPQV
    |...  ||| .|| | . | . ||...|| .
DPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_14216.AA CAMK 14-201 22 4.1e-55 175.69 In-house 1-323 (425) Show / Hide 
Range on Protein: 14-201
Range on HMM: 1-323/425
Sequence Identity: 22% (75 aa)

YIDSGSFGKVYRAYSKDTG------------ELVAVKEIDLYYLT--------------------------DNLLDKIEQEFSTAQK-------LDHPNI
 . .||||||.... | |.            . ||.| ||   |.                          .. ......| .  .|       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LKYKTIRKD-------------------EYYYLLEM---ELCDQ-----SLEDVIRSQRYLG-----------YPFQEPYIWYVIGQIVNGLAYMHSQSI
.|   .  |                   . .. . |   |.|.       | | |..... |             |.|    ... ||. ...|.||. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

TSSTIVHRDLKPGNILFTDTH------------------IKLGDFGLARETSG------------------------KSRMTTCTGTPVYMA-PEVQRG-
     ||||||| |||..| .                  ||. |||.|..  .                           |.|. ||| ||| ||| .| 
-----VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

-------------DFYGTAADIWSLGCI
             . || ..|.||.|.|
GHCNMQNATDEEKPYYGPKCDMWSCGVI
Kinase GL50803_14216.AA CAMKL 9-262 29 3.1e-54 171.4 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-297/297
Sequence Identity: 29% (89 aa)

YDSPEYIDSGSFGKVYRAYS-KDTGELVAVKEID--LYYLTDNLLDK-----------IEQEFSTAQKLD---HPNILK-YKTIRKDEY-----YYLLEM
|.  . .  ||||||  |   . ||| ||.| ||     . .. ...           |..| .  ..|.   |||| | | .|  .|.     .. | |
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELCDQS---LEDVIRSQRYLGYPFQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFTDTH---IKLGDFGLARETS-G----KSRMTTCTG
|.|.     | | |..... . ...|.       ||| ...|.||. |     ||||.|| |||... .   ||. |||.. .   .       ..|. |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGI-----VHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCG

TPVYMAPEVQRG--D-FYGTAADIWSLGCIILEICTLKPIPWSTEHL--------KDNPQITIDTTYY------SEDLATLIRSCLQLDSNARPTAEEIL
.| |||||.  |  . ..| ..||||.| .||        |.  ...        .   .| .. .|.      | |.  |||. || . . |||...|.
SPPYMAPEIFQGNNKPYDGPKVDIWSCG-VILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

SHPQV
.|| .
NHPWM
Kinase GL50803_14216.AA ULK 9-262 26 1.3e-52 181.16 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-324/324
Sequence Identity: 26% (87 aa)

YDSPEYIDSGSFG-KVYRAYSKDT---GELVAVKEIDLYYLTDNLLD--------KIEQEFSTAQKLD---HPN--ILKYKTIRKDE--YYYLLEMELCD
|   . . .|||| |||... |.|   ...||.| ||. .. .. ..        ....| .. .||.   |||  | |.. . ..    .. . ||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

Q-SLEDVIRSQRYL-----GYPFQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFTDT-------------HIKLGDFGLARE----TSGK
.  ||. |  ...|     .  . |. .  .. ||.||. ..|..      |.|||.|| ||| ..              ..|..|||.|.     .  .
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHN-----IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

SRMTTCT------GTPVYMAPEVQRGD----FYGTA-ADIWSLGCIILEICTLK-P--IPWSTEHL----------------KDNPQITIDT----TYYS
  ..||       ||| ||||... |      |... .||||||||. |. . | |   .  ..                    | .| ..        |
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKIS

EDLATLIRSCLQLDSNARPTAEEILSHPQV
...  ||| .|| | . | . |||..|| .
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_14216.AA Ciliate-E2 9-262 23 1.3e-49 168.52 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

YDSPEYIDSGSFGKVYRAYSKDTGEL------------------VAVKEIDLYYLTDNLLDKIEQEFSTAQ----------------KLDHPNILKYKTI
|.  . | .|.||.||..  . ....                  |..|.. . ..  | .  |.|| .  .                .|.||||.|..  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

RK--DEYYYLLEMELCDQ-SLEDVIRSQRYLG-------YPFQEPYIWYVIGQIVN---------------GLAYMHSQS-ITSSTIVHRDLKPGNILFT
 .  |. .. | ||.|.. .|.| |....           .| |  | |.. ||..               .| |.||.  |     .|||.|| |||| 
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNI-----IHRDIKPENILF-

DTHIKLGDFGLARETSGK-------------------SRMTT-------------CTGTPVYMAPEVQRGDF---------YGTAADIWSLGCIILEICT
   ||. ||||... . .                   ||...             . ||| |||||. .|           |....||||||.|. | ..
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

LKPIPWSTEHLKDNPQITID-----------------TTYYSEDLATLIRS----CLQLDSNARPT-AEEILSHPQV
 || |.  .  . . .| ..                 . . |..   ||.     .|| | . |.| .|.|| ||  
GKP-PF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_14216.AA NEK 17-210 33 7.2e-49 168.67 In-house 9-224 (286) Show / Hide 
Range on Protein: 17-210
Range on HMM: 9-224/286
Sequence Identity: 33% (72 aa)

SGSFGKVYRAYSKDTGEL-----VAVKEIDLYYLTDNLLDKIE-QEFSTAQKLDHPNILKYKTIRKDEY--YYLLEMELCDQ--SLEDV---IRSQRYLG
.|||||||.. .| .|       .. |.|..  ...   ..   .|    ..|.|||| ||.    .|   .   .|| |.    |..    |  |.  |
QGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKG

YPFQEPYIWYVIGQIVNGLAYMHSQSIT-SSTIVHRDLKPGNILFTDTH-----IKLGDFGLARETS-GKSRMTT-CTGTPVYMAPEVQRGDFYGTAADI
 .|.| .|| .  |.. .| |||...      |.|||.|| ||  |. .     .|.||||.... . ...  .| ..||| ||.||| ..  |.  .||
KYFEEEQIWDWFIQMCLALKYMHDRK-GPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNKPYNNKSDI

WSLGCIILEICTL--KP
|||||.. |.|||  |.
WSLGCVLYEMCTLKPKH
Kinase GL50803_14216.AA Ciliate-E2-Unclassified 9-262 21 1.5e-46 159.5 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-352/352
Sequence Identity: 21% (77 aa)

YDSPEYIDSGSFGKVYRAYSKDTGELV-----AVKEIDLYYLTDNL----------LDKIEQEFSTA----------QKLDHPNILKYKTIRKDEYYYLL
|   . | .|.|||||... |... ..     . | ..   .  .           . ...  ..            . ..||.|.|.  . .|. .  .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

EMELCDQ-SLEDVIRS-------------QRYLGYPFQEPYIW-----YVIGQIVNGLAYMHSQ-SITSSTIVHRDLKPGNILFTDT----HIKLGDFGL
 ||.|.. .|.. |..             ... .  |.|  .      . . ||..|| |.|..       |.|||.|| ||||..     .||. |||.
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNN-----IIHRDIKPENILFDNNGKNYYIKIIDFGI

AR-------ETSGK----------SRMTTCTGTPVYM----APEVQRGDFYG----TAADIWSLGCIILEICTLKPIPWSTEHLKD--------------
..       .. ..           .|.|..||| ||    |||| .|  |.     ..||||||.|. |... .  | . .  ..              
SKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYR

--NPQITI----------------DTTYYSEDLAT-LIRSCLQLDSNARPTAEEILSHPQV
    |. .                .     .|. . |....|. . | |.|.|.|| ||  
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_14216.AA STE11 9-210 31 3.6e-46 159.7 In-house 1-236 (303) Show / Hide 
Range on Protein: 9-210
Range on HMM: 1-236/303
Sequence Identity: 31% (78 aa)

YDSPEYIDSGSFGKVYRAYSKDTGELVAVKEIDL-YYLTD-----NLLDK------IEQEFSTAQKLDHPNILKYKTIRK---DEYYYLLEMELCDQ-SL
. . | |..|.||.||... .|||||.|||.| .  . ..     . ...      |..| .  ..|.|.|| .|  .     .....   || | . ||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

EDVIRSQRYLGY-P--FQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFTD--THIKLGDFGLARETSGKSRMTTC-----------TGTP
....|    ... |  |.|. | . . ||  ||.| ||.      |.|||.|. |||     ...||.||| |.  ..  ..|.            ||||
SSMLR----HKWGPMKFDEMVIRKYTKQILEGLQYLHSHG-----IIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTP

V--------YMAPEVQRGDF---YGTAADIWSLGCIILEICTLKP
         .||||| ..     ||..||||||||...| .| ||
YNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKP
Kinase GL50803_14216.AA STE20 9-210 32 1e-40 141.58 In-house 1-225 (288) Show / Hide 
Range on Protein: 9-210
Range on HMM: 1-225/288
Sequence Identity: 32% (76 aa)

YDSPEYIDSGSFGKVYRAYSKDTGEL----VAVKEIDLYYLTD--NLLDKIEQEFSTAQKLDHPNILKYKTIRKDE----YYYLLEMELCDQ-SLEDVIR
|.  | | .||.||||.|| |.|||.    ||.| ..|    .  . .. |..| |  ....|||| || .    .        . ||.|.  || |...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

-----SQ-RYLGYPFQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFTDT-HIKLGDFGLARETSG-----KS-RMTTCTGTPVYMAPEVQ
      .    |.|..|..| |.  ... ||.| ||.      |.|||.| .||| |.   .|| |||..   .      .. .  |  ||| .||||| 
HCMKCGKNHK-GHPMNEEQIAYICREVLQGLDYLHSN-----HIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVI

RG-----DFYGTAADIWSLGCIILEICTLKP
..       |.. .||||||  ..|  . .|
QCMEGPDKGYDYKCDIWSLGITAIEMAEGEP
Kinase GL50803_14216.AA TyrKc 9-262 22 3.9e-16 38.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-262
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

YDSPEYIDSGSFGKVYRAYSKDTGELVAVKEIDLYYLTDNLLDKIEQEFSTAQKL--DHPNILKYKTIRKDE-------YYYLLEMELCDQ-SLEDVIRS
    . . .| ||.||..  |   . |||| .  .      .  . .| .   ||  .||||..   .  ..         ... ||...  .| | .|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QRYLGYPFQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFTDTH-IKLGDFGLARETSGK------SRMTTCT---GTP--V---YMAPEV
 |     .. .   .   || .| .| ||.      ..||||   |.| .. | .| .||||.|.   .      . . . .   |.   .    ||||.
HRPK---LCMKDLLSFCWQIACGMEYLHSK-----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

QRGDFYGTAADIWSLGCIILEICTLKPIPWST------------EHLKDNPQITIDTTYY-------SEDLATLIRSCLQLDSNARPTAEEILSHPQV
 .   . |. |.|| |  . ||.|.   |..             |..|.     .   .|       .... .....| . | . ||| .||  | . 
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_14216.AA Pkinase_Tyr 17-208 27 1.2e-12 43.42 Pfam 9-210 (270) Show / Hide 
Range on Protein: 17-208
Range on HMM: 9-210/270
Sequence Identity: 27% (57 aa)

SGSFGKVYRAYSK----DTGELVAVKEIDLYYLTDNL--LDKIEQEFSTAQKL-DHPNILKYKTIRK-DEYY--YLLEMELCDQ-SLEDVIRSQRYLGYP
.|.||.||... |    .|.  |||| .   . ..    ...  .| ..  .| .||||...  .   ..    ... ||..   .| |  |..|  . |
EGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQP

FQEPYIWYVIGQIVNGLAYMHSQSITSSTIVHRDLKPGNILFT-DTHIKLGDFGLARET--SGKS-RMTTCTGTPV-YMAPEVQRGDFYGTAADIWSLGC
.  . .     || .|..| .|.      ..||||   |.| | . ..| .||||||     .   |... .  |.  ||||. .   . |. |.|| | 
LTMKDLLQMCWQIAKGMEYLESKN-----CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGV

IILEICTL
 . ||.|.
LMWEIFTY
Kinase GL50803_14216.AA NEK 230-262 41 9.2e-12 38.08 In-house 253-286 (286) Show / Hide 
Range on Protein: 230-262
Range on HMM: 253-286/286
Sequence Identity: 41% (14 aa)

Y-YSEDLATLIRSCLQLDSNARPTAEEILSHPQV
. ||.||  ||...|| |   ||....||..|..
RMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_14216.AA CAMK 232-262 41 8.4e-09 23.74 In-house 395-425 (425) Show / Hide 
Range on Protein: 232-262
Range on HMM: 395-425/425
Sequence Identity: 41% (13 aa)

SEDLATLIRSCLQLDSNARPTAEEILSHPQV
|..   |||..|| | . |.|.|..|.|| .
SQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_14216.AA STE20 231-262 37 5e-06 18.23 In-house 257-288 (288) Show / Hide 
Range on Protein: 231-262
Range on HMM: 257-288/288
Sequence Identity: 37% (12 aa)

YSEDLATLIRSCLQLDSNARPTAEEILSHPQV
.| ..  .. .||| | . ||||.. |.|| .
WSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase GL50803_14216.AA STE11 232-262 38 1.6e-05 16.22 In-house 273-303 (303) Show / Hide 
Range on Protein: 232-262
Range on HMM: 273-303/303
Sequence Identity: 38% (12 aa)

SEDLATLIRSCLQLDSNARPTAEEILSHPQV
||..   .| |.. | . |||| . | || .
SEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase GL50803_14216.AA Pkinase_Tyr 232-262 32 0.273631 4.99 Pfam 242-270 (270) Show / Hide 
Range on Protein: 232-262
Range on HMM: 242-270/270
Sequence Identity: 32% (10 aa)

SEDLATLIRSCLQLDSNARPTAEEILSHPQV
.... .|...| . | . ||| .||  | | 
PDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Ank GL50803_14216.AA Ank 393-413 28 0.030014 12.37 Pfam 1-21 (33) Show / Hide 
Range on Protein: 393-413
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

EGASALMVAAWYGFSDCVELL
.| ..|..|. .|  ..|..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14216.AA Ank 424-449 34 0.003172 15.89 Pfam 1-26 (33) Show / Hide 
Range on Protein: 424-449
Range on HMM: 1-26/33
Sequence Identity: 34% (9 aa)

EGTSALMLAAQQDNENVVEQLLEFEA
.| ..|.||.. ....||. ||.  |
DGFTPLHLACRCGHTEVVKMLLQHGA
Ank GL50803_14216.AA Ank 455-475 19 0.209026 9.33 Pfam 1-21 (33) Show / Hide 
Range on Protein: 455-475
Range on HMM: 1-21/33
Sequence Identity: 19% (4 aa)

QGRTAMMFAAQYNSSKCTSLL
 |.|. . |..... .. ..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14216.AA Ank 486-511 50 1e-06 27.93 Pfam 1-26 (33) Show / Hide 
Range on Protein: 486-511
Range on HMM: 1-26/33
Sequence Identity: 50% (13 aa)

SGSTALMIAAECGHSEIVQLLLKHEA
 | |.|..|..||| |.|..||.| |
DGFTPLHLACRCGHTEVVKMLLQHGA
Ank GL50803_14216.AA Ank 517-537 33 0.001265 17.33 Pfam 1-21 (33) Show / Hide 
Range on Protein: 517-537
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

NGWTALMSATQRGHSNIMRIL
.|.|.|. | ..|| .... |
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14216.AA Ank 548-568 28 0.027624 12.5 Pfam 1-21 (33) Show / Hide 
Range on Protein: 548-568
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

TGQTALMVAAMNGQEKAAQIL
 |.|.|..|...|... .. |
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14216.AA Ank 579-599 38 0.000289 19.64 Pfam 1-21 (33) Show / Hide 
Range on Protein: 579-599
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

EGLTALMYAAQWNYPEIVKVL
.| |.|..|......|.|| |
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14216.AA Ank 610-642 24 0.979858 6.91 Pfam 1-33 (33) Show / Hide 
Range on Protein: 610-642
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

DGRRAVQFAAEWGCLACVDMLMDYEGDQAKLTN
||. .   |...|.. .| ||...  |    ..
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_14216.AA Ank 701-722 27 0.165049 9.7 Pfam 1-22 (33) Show / Hide 
Range on Protein: 701-722
Range on HMM: 1-22/33
Sequence Identity: 27% (6 aa)

TGYSSLMHAVAHGNVQFARMLV
 |.. |. |. .|... ..||.
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_14216.AA Ank 670-700 27 0.913409 7.02 Pfam 1-33 (33) Show / Hide 
Range on Protein: 670-700
Range on HMM: 1-33/33
Sequence Identity: 27% (9 aa)

IGTTALMYAGMVNSCAVAALLLS--AETGQLDK
 | |.|..| . ..  |. .||.  |.    |.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD