GL50803_14661

Species: G.lamblia
Alias: GL50803_14661, GK016
External Links: GiardiaDB ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_14661.AA Protein None 469 None Fasta, JSON
GL50803_14661.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of GL50803_14661.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_14661.AA CAMKL 12-266 34 3.6e-98 313.89 In-house 1-297 (297) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-297/297
Sequence Identity: 34% (105 aa)

YEVSELLGSGAFAKVRLATR-KDTGKKYAVKIIKKVGLS--------------QRAADRLNLEIAVTKGIS---HPNVIKMHEVIGTSSK------FWLV
|.. . || |.|.||.|||  . ||.|.|.|||.| ...              ..   |.  ||.  | ..   |||.||..||| |...      ..||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MDYHANGE--LLKHMKTK------LSDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDG--HLVITDFGLGAISYN----PDKTFYSQATFCGS
| |. .||  |. . . .      .. ..|  || || .|. |||. ||.|||.| ||.|. ..|   . |.|||....  .    |....    |||||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLK---TFCGS

THYIAPEVSSG--SRYDGRKSDIWSLGIMLYAMLIGKLPFPSDNY--------EVLVESMLNRRYDPIPSFVNDQAKNLLEALLEPDPRTRPDWREIFNY
 .| |||. .|   .|||.| ||||.|..||||. |.|||  |.|        . . . |    |.||...|  ....|.  .|...|  ||   .| | 
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

PWI
|| 
PWM

Kinase GL50803_14661.AA CAMK 17-266 23 1.6e-88 285.32 In-house 1-425 (425) Show / Hide
Range on Protein: 17-266
Range on HMM: 1-425/425
Sequence Identity: 23% (98 aa)

LLGSGAFAKVRLATRKDTG------------KKYAVKIIKKVGLS--------------------------QRAADRLNLEIAVTKG-------ISHPNV
 ||.|.|.||.|...| |.            .|.|.|||.|  |.                          ..  ...  ||.. |        ..|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKMHEVIG------------TSSK--------FWLVM---DYHANGEL----LKHMKTK-----------------LSDDQAFDYFIQIACALRYCHRFG
||..||.             | ||        ...||   .|  .|||    . . . .                 .. ..|  || ||..|..|||  .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

ICHRDLKFENVLVAND-----------------GHLVITDFGLGAISYNPDKTFYS--------------------QATFCGSTHYIA-PEVSSG-----
|.||||| ||.|. ..                 . . |.|||. ..    .. |.                       ||||. .|.| ||| .|     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------SRYDGRKSDIWSLGIMLYAMLIGKLPFPSD-------------NYEVLVESMLNRRYDPIPSFVND-----------------------QAK
         .|.|.|.|.||.|..||.|| |..|| .|             |.. | |  .. .|| .|... .                       ..|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLLEALLEPDPRTRPDWREIFNYPWI
.|.  .|..||  |.   .. | ||.
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase GL50803_14661.AA AGC 12-266 22 9.8e-88 226.17 In-house 1-395 (395) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-395/395
Sequence Identity: 22% (92 aa)

YEVSELLGSGAFAKVRLATRK------DTGKKYAVKIIKKVG-LSQRA---ADRLNLE------------IAVTKGIS----------HPNVIK-MHEVI
.|.  ..| |.| ||.|. .|      |||| ||.|..||     ..     .. . |              . . ..          ||...| .|   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

GTSSK--FWLVMDYHA---------NG-ELLKHMKT-----KLSDDQAFDYFIQ-------IACALRYCHR-FGICHRD-LKFENVLVANDGHLVITDFG
 . ..    .||.|.           | ||. |..      ... ..|  |. .       |..|| | |.  || ||| || ||.|  .|||. .||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LGAI-------------------------------------SYNPDKTFY-----------SQATFCG--STHYIAPEVSSGSRYDGRKSDIWS--LGIM
|  .                                     . . .. ..              ||||  . .|.|||.       |.  |.||  ||..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNN-MSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCL

LYAMLIGKLPFPSDN----------YEVLVESMLNRR-----YDPIP----------SFVNDQAKNLLEALLEPDPRTRPD----------WREIFNYPW
.| ||.|. || .||           . . .. .|.|       ..|          ... ..||.|.. ||..||. |.             || | ||
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

I
 
F

Kinase GL50803_14661.AA S_TKc 12-266 32 4.4e-87 296.52 SMART 1-231 (231) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLSQRAADRLNLEIAVTKGISHPNVIKMHEVIGTSSKFWLVMDYHAN--GELLKHMKTK------
||. ...|.|||.||.... |.||...|.||||         ...  ||.. |   |||..|...|. . .....||.|  .  |.|....| .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGLGAISYNPDKTFYSQATFCGSTHYIAPEVSSGSRYDGRKSDIWSLGIML
  ..  .|  |. ||.||| |||. ||.||||| ||.|. .  |. |.|||| ..            ||||. .|.||||     |...|.|.||.|..|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YAMLIGKLPFPSDNYEVLVESMLNRRYDPIPSFVNDQAKNLLEALLEPDPRTRPDWREIFN-------YPWI
| || |. |||  ..... . ..            ..||.... .|. ||. ||   |...        ||.
YEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_14661.AA Pkinase 12-266 29 1.3e-85 295.52 Pfam 1-293 (293) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLSQRAADRLNL--EIAVTKGISHPNVIKMHEVIGTSSKFWLVMDYHANG----ELLKHMK----
|.. . .|||.|..|.....|.|||..|||||||.. .     .. .  ||.. | ..|||.......  .... ..||.|. .|    .|  ...    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TKL--SDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHL----VITDFGLGAIS-YNPDKTFYSQATFCGSTHYIAPEVSSGSRYDGRKSDI
...  |.... .|. ||...| |||. ||.||||| ||.|. |.||.     |.|||| .   | ..  ..   ||||. .|.||||  |..|.|.|.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MT---TFCGTPWYMAPEVIRGGQYYGPKVDM

WSLGIMLYAMLIGKLPFPSD------NYEVLVESMLNRRYDPIPSFVN--------------------DQAKNLLEALLEPDPRTRPDWREIFNYPWI
||.|..|| || |..|||..      .  ....  . ....   .  .                    . .| ... .|..||  || ...|.. ||.
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase GL50803_14661.AA MARK 12-266 38 1.3e-83 273.18 In-house 1-262 (262) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-262/262
Sequence Identity: 38% (102 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLSQ-RAADRLNLEIAVTKGISHPNVIKMHEVIG--TSSK-FWLVMDYHANGELLKHMKTK----
|..   .| |..|||.||. | ||.|.|.||..|  |.   .   .  ||.. | ..|||.||...||   |... ..|.|.|  .|||. ..| .    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LSDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDG--HLVITDFGLGAISYNPDKTFYSQATFCGSTHYIAPEVSSGSRYDGRKSDIWSLGIML
|. . |  .| || .|. |||. .|.|||.| ||.|.  .|     |.|||....  .  |      ||||.  | |||. .. .|||.| ||||||. |
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK----LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVL

YAMLIGKLPFPSDN--YEVLVESMLNRRYDPIPSFVNDQAKNLLEALLEPDPRTRPDWREIFNYPWI
|.|. |..||  |.  |. | . .|. .|| ||..| ....||.  || ..|  ||.  || . ||.
YFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase GL50803_14661.AA AMPK 12-266 38 2.1e-76 226.38 In-house 1-254 (254) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-254/254
Sequence Identity: 38% (99 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGL-SQRAADRLNLEIAVTKGISHPNVIKMHEVI-GTSSKFWLVMDYHANGELLKHM--KTKLSDD
| . . .| |.| || ..| . ||.| |.||. |  . .|    |.  ||   | . ||..|.  |||  | . ...|| | ..|||      ...|. .
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGLGAISYNPDKTFYSQATFCGSTHYIAPEVSSGSRYDGRKSDIWSLGIMLYAMLIG
.|  .| ||  .. |||| .| ||||| ||.|   . .. | ||||  . ..  .. .   | |||  | |||. || .| |.. |||| |. ||||| |
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNM-MKDGEFLK---TACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCG

KLPFPSDNYEVLVESMLNRRYDPIPSFVNDQAKNLLEALLEPDPRTRPDWREIFNYPWI
.|||  .|  .|    .| .| .||.|....||.|.. .|..||  | .  .| | || 
YLPFDDENTPTLYKKIKNGEY-YIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF

Kinase GL50803_14661.AA Ciliate-E2 12-266 21 1.8e-69 237.14 In-house 1-365 (365) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

YEVSELLGSGAFAKVRLATRKDTGK------------------KYAVKIIKKVGLSQRAADRLNLEIAVTKGIS----------------HPNVIKMHEV
|.. ...|.|.|..|...... ..|                  |...||. .  ....    .. || . . |                 |||.|||.|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

IG--TSSKFWLVMDYHANGELLKHMK-------------TKLSDDQAFDYFIQIAC---------------ALRYCHRFG-ICHRDLKFENVLVANDGHL
    . ... |||.|   |.|....|              .... .. ... ||.                ||.|.|  . |.|||.| ||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

VITDFGLGAISYNP-----------DKTFYSQ------------------ATFCGSTHYIAPEVSSGSRYDG--------RKSDIWSLGIMLYAMLIGKL
 |.||||  .  ..            ..| ..                   |.||. .| |||. .|  ||.         |.||||||..|| || ||.
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFPSDNYEVLVESMLNRRYDPIPSF--------------------VNDQAKNLLEA----LLEPDPRTRPD-WREIFNYPWI
||           . .    .|  .                    . ...|.|.      .|. ||  |.. | .|.| ||.
PF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase GL50803_14661.AA Ciliate-E2-Unclassified 12-266 24 4.9e-65 222.37 In-house 1-352 (352) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-352/352
Sequence Identity: 24% (86 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLSQ------RAADRLNLEIAVTKG------------------ISHPNVIKMHEVIGTSSKFWLV
|.. . .|.|.|.||... .|.....|| |..||.             . .| .... .                   . ||...||...  .  .. .|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MDYHANGELLKHMKTK-------------------LSDDQAF-----DYFIQIACALRYCHRFG-ICHRDLKFENVLVANDG---HLVITDFGL-GAISY
|.|  .|.|....| .                   ... ||      .|| || ..| |.|. . |.|||.| ||.|. |.|   .. |.|||.   . .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

NPDKTFYS------------QATFCGSTHYI----APEVSSGSRYDGR---KSDIWSLGIMLYAMLIGKLPFPSDNYEV---------------LVESML
|.... ..            . ||||.  |.    ||||  |  ||..   |.||||||. ||.|| |..||.. |.|                 ...  
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

NRR------YDP--IPSFVNDQAKNLLE----ALLEPDPRTRPDWREIFNYPWI
. .      ...  ||  ....||....     .|. .|  |... .|.| ||.
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase GL50803_14661.AA MELK 12-266 35 4.3e-64 217.83 In-house 1-254 (254) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-254/254
Sequence Identity: 35% (90 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLSQRAADRLNLEIAVTKGISHPNVIKMHEVIGTSSKFWLVMDYHANGELLKHM--KTKLSDDQA
||| . .|.| ||||.||.   |... |.||. |  | .    |.. |.   | ..| .. ... .| |  |...||.| . ||.. ..  . .|.....
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLGHDLP-RVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYIIRQDRLEEEET

FDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGLGAISYNPDKTFYSQATFCGSTHYIAPEVSSGSRYDGRKSDIWSLGIMLYAMLIGKL
  .| ||  |. | |  |  ||||| ||.|. .| || . |||| | .    |  .   | |||  | |||. .| .| |   |.||.||.||....| |
RHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKT-KGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFL

PFPSDNYEVLVESMLNRRYDPIPSFVNDQAKNLLEALLEPDPRTRPDWREIFNYPWI
||  || ...   ..   |.  | ..  ..|.|| ..|  ||. |   ... | ||.
PFDDDNMMIMYKKIMSGCYE-EPKWLSPESKQLLRHMLQVDPKKRISMKNLLNHPWV

Kinase GL50803_14661.AA BRSK 12-266 38 1.3e-62 212.19 In-house 1-254 (254) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-254/254
Sequence Identity: 38% (100 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLS--QRAADRLNLEIAVTKGISHPNVIKMHEVIGTSSKFWLVMDYHANGELLKHM--KTKLSDD
| .   || |   .|.| . ..|||| |.||| |  ||       .   |||. | | ||.|.||..|  ..   .|.. . . |||   .  | .|   
YRLEKTLGKGQTGLVKLGVHCVTGKKVAIKIINKEKLSNKESMLMKVEREIAIMKLIDHPHVMKMYDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPK

QAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGLGAISYNPDKTFYSQATFCGSTHYIAPEVSSGSRYDGRKSDIWSLGIMLYAMLIG
 |  .| ||  || .||   ||||||| || |  ..    | |||.. .  . |       | ||| ||  ||| .|  ||||| |.|| |. |||.|.|
EARKFFRQIISALDFCHSHNICHRDLKPENLLLDEKNNIKIADFGMASLQVK-DMML---HTSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG

KLPFPSDNYEVLVESMLNRRYDPIPSFVNDQAKNLLEALLEPDPRTRPDWREIFNYPWI
.|||  ||   | |   .  .  .| |.   . .|| ...| ||  |    ||.  || 
ALPFDDDNLRQLLEKVKRGVFH-MPHFIHPDCQDLLRGMIEVDPDKRISLKEIQKHPWY

Kinase GL50803_14661.AA QIK 12-266 31 1.8e-61 210.53 In-house 1-272 (272) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-272/272
Sequence Identity: 31% (87 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLSQRAADRLNLEIAVTKGISHPNVIKMHEVIGTSSKFWLVMDYHANGELLKHMKT--K------
|..   .| | || |.||. . | .| |.||| |  | .    ..  |... | ..||..||  .|. | .  ..|..|  |||.  ..    .      
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKMV

--------------LSDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGLGAISYNPDKTFYSQATFCGSTHYIAPEVSSGSRYDG
              .. ..|   | ||. |  |||. .| ||||| ||.|  |.    | |||..   . ....    .|.|||  | |||.  |  |||
NSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNW-FKQGQLL---MTWCGSPPYAAPEMFEGKEYDG

RKSDIWSLGIMLYAMLIGKLPFPSDNYEVLVESMLNRRYDPIPSFVNDQAKNLLEALLEPDPRTRPDWREIFNYPWI
 |.||||.|. ||..  |.|||.... . | ...|  ..  || |.      |    |  ||  |     | . .|.
PKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFR-IPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM

Kinase GL50803_14661.AA Pkinase_Tyr 12-153 27 2.3e-15 52.63 Pfam 1-157 (270) Show / Hide
Range on Protein: 12-153
Range on HMM: 1-157/270
Sequence Identity: 27% (43 aa)

YEVSELLGSGAFAKVRLATRK----DTGKKYAVKIIKKVGLSQRA--ADRLNLEIAVTKGI-SHPNVIKMHEVIG-TSSK--FWLVMDYHANGELLKHMK
 .  . ||.||| .|...| |    .|. . |||.. | | ....   . .  |... | . .|||..... |.   .     ..|| | ..| ||.. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

TK------LSDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGL
..      |.  .  .. .|||... | .. .. ||||   |.||.....  |.||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGL

Kinase GL50803_14661.AA TyrKc 12-266 22 4e-15 21.91 SMART 1-280 (280) Show / Hide
Range on Protein: 12-266
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

YEVSELLGSGAFAKVRLATRKDTGKKYAVKIIKKVGLSQRAADRLNLEIAVTKGI--SHPNVIKMHEVIGTS-------SKFWLVMDYHANGELLKHM-K
 .  . ||.||| .|...| |    . ||| .|.          .  |. . . .  .|||..... |. ..          ..|| | ..| |...  |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TK--LSDDQAFDYFIQIACALRYCHRFGICHRDLKFENVLVANDGHLVITDFGLGAISYNPD-------KTFYS----QATFCGSTHYIAPEVSSGSRYD
..  |. ..  .. .||||  .| |. .. ||||   |.||.....  |.|||| .     |       ..  .    .. .       |||.   ... 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGL-SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

GRKSDIWSLGIMLYAML-IGKLPFPS-----DNYEVLVESMLNRRYDPIPSF--------VNDQAKNLLEALLEPDPRTRPDWREIFNYPWI
  |||.|| |.... ..  |. | |       . . ..|   .... |.|            |   .. .   . ||  ||  .||  .  .
-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase GL50803_14661.AA Pkinase_Tyr 191-202 50 5.831325 0.49 Pfam 194-205 (270) Show / Hide
Range on Protein: 191-202
Range on HMM: 194-205/270
Sequence Identity: 50% (6 aa)

KSDIWSLGIMLY
|||.|| |. ..
KSDVWSFGVLMW