GL50803_14786

Species: G.lamblia
Alias: GL50803_14786, GK284
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_14786.AA Protein None 1084 None Fasta, JSON
GL50803_14786.kin_dom Protein Kinase Domain None 284 None Fasta, JSON

Protein domain

Protein domains of GL50803_14786.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_14786.AA ULK 214-293 22 8.9e-14 44.55 In-house 218-329 (329) Show / Hide
Range on Protein: 214-293
Range on HMM: 218-329/329
Sequence Identity: 22% (25 aa)

MAPELLLDS-EEVSPS-GAVDIWSVGSVLYEMATGKTY---DSAIDPT-----TNLRT-----------------------YSFEFQSMLRSMLSIKQSD
|||..| .  |.  ..   .||||.| ..||| .||..     . |        ...                         | |... .| || ....|
MAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKD

RPTFEDLLKAERI
| ..|.|.. . .
RISWEELFNHPWF

Kinase GL50803_14786.AA AGC 214-293 16 9.4e-14 30.45 In-house 274-395 (395) Show / Hide
Range on Protein: 214-293
Range on HMM: 274-395/395
Sequence Identity: 16% (21 aa)

MAPELLLDSEEVSPSGAVDIWS--VGSVLYEMATG--------------------KTYDSAI-------DPTTNL----------RTYSFEFQSMLRSML
|||| |        . |.|.||  .| ..||| ||                    ..... .       .. .            |  | | .. .. .|
MAPEIL-------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLL

SIKQSDRPT----------FEDLLKAERI
    ..|..          .|.. . .  
CKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase GL50803_14786.AA ULK 214-293 21 3.4e-13 43.21 In-house 214-324 (324) Show / Hide
Range on Protein: 214-293
Range on HMM: 214-324/324
Sequence Identity: 21% (24 aa)

MAPELLLDS-EEVSPS-GAVDIWSVGSVLYEMATGKTY---DSAIDPT-------------------TNLRTY--------SFEFQSMLRSMLSIKQSDR
|||..| .  |.  ..   .||||.| ..||| .||..   . . |                     .... .        | |... .| || ....||
MAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR

PTFEDLLKAERI
 ..|.... . .
ISWEEIFNHPWF

Kinase GL50803_14786.AA Ciliate-E2 214-293 19 2.1e-09 28.41 In-house 254-365 (365) Show / Hide
Range on Protein: 214-293
Range on HMM: 254-365/365
Sequence Identity: 19% (23 aa)

MAPELLLDSEEVS------PSGAVDIWSVGSVLYEMATGKTYDSAIDPTTNLRTYSFEFQ--------------------------SMLRS----MLSIK
|||| |   ..         . ..||||.| .|||| .||.         .     ..|.                           ...     ||  .
MAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-----QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKD

QSDRPT-FEDLLKAERI
.. |.| .|..|. . .
PEKRITGWEQILNHPWF

Kinase GL50803_14786.AA RSKL 232-252 42 3.3e-08 14.31 In-house 360-380 (436) Show / Hide
Range on Protein: 232-252
Range on HMM: 360-380/436
Sequence Identity: 42% (9 aa)

DIWSVGSVLYEMATGKTYDSA
|.|| |.||||. .|... ..
DWWSYGAVLYELLCGMSLYQC

Kinase GL50803_14786.AA STE11-Unclassified 214-247 47 4.4e-08 24.81 In-house 202-235 (308) Show / Hide
Range on Protein: 214-247
Range on HMM: 202-235/308
Sequence Identity: 47% (16 aa)

MAPELLLDSEEVSPSGAVDIWSVGSVLYEMATGK
||||..  | . . ....||||.| . .||||||
MAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGK

Kinase GL50803_14786.AA CDK 215-247 47 1.8e-07 19.83 In-house 187-222 (284) Show / Hide
Range on Protein: 215-247
Range on HMM: 187-222/284
Sequence Identity: 47% (17 aa)

APELLLDSEEVSPSGAVDIWSVGSVLYEMAT---GK
|||||| |.. | . ..|.|||| ...||.|   .|
APELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRK

Kinase GL50803_14786.AA MSK 211-247 41 2e-07 21.17 In-house 169-207 (277) Show / Hide
Range on Protein: 211-247
Range on HMM: 169-207/277
Sequence Identity: 41% (16 aa)

LSHMAPELLLD--SEEVSPSGAVDIWSVGSVLYEMATGK
|  ||||.| .  ....  . |.|.||.| .||.| ||.
LHYMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQ

Kinase GL50803_14786.AA Pkinase 214-248 42 2.9e-07 26.78 Pfam 178-210 (293) Show / Hide
Range on Protein: 214-248
Range on HMM: 178-210/293
Sequence Identity: 42% (15 aa)

MAPELLLDSEEVSPSGAVDIWSVGSVLYEMATGKT
||||....... .|  .||.||.| .||||..|..
MAPEVIRGGQYYGP--KVDMWSCGCILYEMLCGRP

S_TKc GL50803_14786.AA S_TKc 10-293 13 8.3e-07 -77.11 SMART 1-231 (231) Show / Hide
Range on Protein: 10-293
Range on HMM: 1-231/231
Sequence Identity: 13% (42 aa)

YRFIGLANIGGDELIYKLLDETTEQEVFCTIFTFDQLRKRAYTELLSFIQIYTALDHRGLMRYRAIETEPADLRLFFMTSTYNVNLAKLNLLMRQEGKS-
|... .   |.    ||  .  | ..| . |       .... |.    .     .|  . ..  .  .    .|.. .   . .|  |  .... |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----YCELALWQVAAQLIDTMTYCNLPR------------------------TRQFGHKSTRLAANSFPHCVLRPFIIVITNSFTQESDLLKLSTNSKQA
    . |   . ...|... . ||   .                         ||.                                            
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------------------------------------------

ALFPLSIKVMPGVLTVGQLRQFQTTAARSHLSHMAPELLLDSEEVSPSG-AVDIWSVGSVLYEMATGKT-YDSAIDPTTNLRTYSFEFQSMLRSMLSIKQ
                        |     .  ||||.|      . .. ..|.||.| .||||..|.. ..  .. . ..   | |. ...| .|    
------------------------TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-SPEAKDFIRKCLQKDP

SDRPTFEDLLK-------AERI
..|||  ..|.        . .
EKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_14786.AA STE 213-247 39 4e-06 17.91 In-house 228-265 (359) Show / Hide
Range on Protein: 213-247
Range on HMM: 228-265/359
Sequence Identity: 39% (15 aa)

HMAPELLLDSE---EVSPSGAVDIWSVGSVLYEMATGK
.|||| ..  .   .   .  .||||.| .. ||||||
WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK

Kinase GL50803_14786.AA Ciliate-E2-Unclassified 230-247 55 1.4e-05 15.4 In-house 250-267 (352) Show / Hide
Range on Protein: 230-247
Range on HMM: 250-267/352
Sequence Identity: 55% (10 aa)

AVDIWSVGSVLYEMATGK
..||||.| .|||| .|.
KCDIWSLGVILYEMLFGY

Kinase GL50803_14786.AA Ciliate-E2-Unclassified 263-293 25 0.007549 5.74 In-house 318-352 (352) Show / Hide
Range on Protein: 263-293
Range on HMM: 318-352/352
Sequence Identity: 25% (9 aa)

SFEFQSMLR----SMLSIKQSDRPTFEDLLKAERI
|.| . ...    .||  ... |.|||..|.   .
SPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase GL50803_14786.AA STE 265-293 32 0.042339 3.36 In-house 329-359 (359) Show / Hide
Range on Protein: 265-293
Range on HMM: 329-359/359
Sequence Identity: 32% (10 aa)

EFQSMLRSMLSIKQSDRPTFEDLLK--AERI
||.  ..  | .  ..||| ..|||   . |
EFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase GL50803_14786.AA Pkinase 265-293 24 1.577706 2.95 Pfam 265-293 (293) Show / Hide
Range on Protein: 265-293
Range on HMM: 265-293/293
Sequence Identity: 24% (7 aa)

EFQSMLRSMLSIKQSDRPTFEDLLKAERI
|... ....|  . ..|||.|..|. . .
ECKDFIKWCLCKDPKKRPTAEQILQHPWF

Ank GL50803_14786.AA Ank 451-474 37 0.000106 21.21 Pfam 1-24 (33) Show / Hide
Range on Protein: 451-474
Range on HMM: 1-24/33
Sequence Identity: 37% (9 aa)

DGTSALMLAAENNSLEVAKLLVSY
|| ..|.||......||.|.|...
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_14786.AA Ank 482-505 45 5e-06 26.01 Pfam 1-24 (33) Show / Hide
Range on Protein: 482-505
Range on HMM: 1-24/33
Sequence Identity: 45% (11 aa)

TGLTALMYAARRGHADLVSLLLNH
 | |.|..|.|.||.. |..||.|
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_14786.AA Ank 513-545 27 0.000124 20.97 Pfam 1-33 (33) Show / Hide
Range on Protein: 513-545
Range on HMM: 1-33/33
Sequence Identity: 27% (9 aa)

RGYTALMHAIDQGHLECIRILVKAETNYSAPNG
 |.|.|. |.  ||.|... |...  .  | . 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_14786.AA Ank 630-653 29 0.122265 10.17 Pfam 1-24 (33) Show / Hide
Range on Protein: 630-653
Range on HMM: 1-24/33
Sequence Identity: 29% (7 aa)

THVTCLMLAAQHHSVELVQMFIHQ
   |.|.||... ..| |.|.. .
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_14786.AA Ank 660-680 33 0.607047 7.66 Pfam 1-21 (33) Show / Hide
Range on Protein: 660-680
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

KGLTALHIAVQELFVDGVTLL
 | |.||.|..   .. |..|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_14786.AA Ank 786-806 33 5.669587 4.16 Pfam 1-21 (33) Show / Hide
Range on Protein: 786-806
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

TGKTALIAAATVGNALAVRAL
 | |.|  |.  |..  |. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_14786.AA Ank 817-849 15 4.094265 4.67 Pfam 1-33 (33) Show / Hide
Range on Protein: 817-849
Range on HMM: 1-33/33
Sequence Identity: 15% (5 aa)

KGWTAMMCCVCRASSTTAQNLCTYIECINALAP
 |.|. .. ... .   .. |  .  ..||   
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_14786.AA Ank 858-878 23 0.193611 9.45 Pfam 1-21 (33) Show / Hide
Range on Protein: 858-878
Range on HMM: 1-21/33
Sequence Identity: 23% (5 aa)

CGWTALVYASAYLNLACIEVL
.|.|.| .|. . .. ... |
DGFTPLHLACRCGHTEVVKML