Gene GL50803_14897 (G.lamblia)

GL50803_14897

Species: G.lamblia
Alias: GL50803_14897, GK184
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_14897.AA Protein None 989 None Fasta, JSON
GL50803_14897.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of GL50803_14897.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_14897.AA S_TKc 10-291 23 1.5e-25 92.08 SMART 1-231 (231) Show / Hide 
Range on Protein: 10-291
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

YDILGIIGHGPYATVFKCRHKATEETHIIKEYLLDAIPRQCISLLRREADLQAQVQIDSILQPCYTFVDHDSLVLYIVLPFLGA--KTLQAAIESAKT--
|.|| .||.| ...|.||||| | .   ||.             .||| ..  . . . | .  ..|.|     ||.|. ...    .|   |.. ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

DQTYFTEDVVWSTAYSLLTILKDLASYPLREDDAPSLKPLHCNLKPTNILFLDENLSMVQLCDCSFSPDLRLTLSSTKIGLKAHKRDADHLYTTAYMAPE
 . .|.| .... .| ..  |. . |             .|. ||| |||. .     . .||  ..  |                      |  |||||
LRFPFPE-HARFYMYQICCALEYCHSHGI----------IHRDLKPENILLDE----HIKICDFGLARQL-----------------TTFCGTPWYMAPE

ILKDKKAHE-TSDIWSLGCILYEMCTMKALVSDTLDAASSESMLSAILPIRKLYGYSDVLNDFLNQMLTQNPSLRPDYDTLLN-------HSRM
.|   .     .|.||.|||||||.. . . .        . |.  |.        |. . ||....|. .|. ||    .|.       |  .
VL---GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_14897.AA Ciliate-E2 196-291 21 2.2e-17 56.19 In-house 248-365 (365) Show / Hide 
Range on Protein: 196-291
Range on HMM: 248-365/365
Sequence Identity: 21% (30 aa)

LYTTAYMAPEILKDKK---------AHETSDIWSLGCILYEMCTMKALVSDTLDAASSESMLSAILPIRKLYGYSDVLN---------------------
..|  |||||||. ||           . .||||||.|||||.. |                           .   ..                     
CGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKW

-----------DFLNQ----MLTQNPSLRPD-YDTLLNHSRM
           |....    ||  .|. |.. .. .|||  .
KSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_14897.AA Ciliate-E2-Unclassified 198-291 25 2.7e-17 56.54 In-house 225-352 (352) Show / Hide 
Range on Protein: 198-291
Range on HMM: 225-352/352
Sequence Identity: 25% (33 aa)

TTAYM----APEILKDKKAHET----SDIWSLGCILYEMCTMKALVSDTLDAA------------SSESMLSAIL------PIRKL----YGYSDVLNDF
|  ||    |||.|. ..  ..    .||||||.|||||.. .   .|. .                . ... |.      |  .     .. |.   ||
TPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDF

LN----QMLTQNPSLRPDYDTLLNHSRM
.|    .||  ||. |.... .|||  .
INDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_14897.AA STE 198-291 22 4.4e-17 56.97 In-house 226-359 (359) Show / Hide 
Range on Protein: 198-291
Range on HMM: 226-359/359
Sequence Identity: 22% (31 aa)

TTAYMAPEILKD-----KKAH-ETSDIWSLGCILYEMCTMKALVSDTLDA-ASSESMLS---------------AILPIRK-----------------LY
|  .||||...      .| . . .||||||| . ||.| |   .|  .  |  . . .                . |.                     
TP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPH

GYSDVLNDFLNQMLTQNPSLRPDYDTLLN--HSRM
 .|. ..||.|. |. .|. ||... ||.  |.  
KWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_14897.AA Pkinase 201-291 21 6.8e-16 57.27 Pfam 177-293 (293) Show / Hide 
Range on Protein: 201-291
Range on HMM: 177-293/293
Sequence Identity: 21% (25 aa)

YMAPEILK-DKKAHETSDIWSLGCILYEMCTMKALVSDTL----DAASSESMLSAILPIRKLYGYS-----------------------DVLNDFLNQML
|||||... ...    .|.||.|||||||.. . . .       . ..   |.  |.. .  . ..                       . . ||.. .|
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

TQNPSLRPDYDTLLNHSRM
...|. ||  . .|.|  .
CKDPKKRPTAEQILQHPWF
Kinase GL50803_14897.AA ULK 201-291 24 3.1e-15 50.55 In-house 213-324 (324) Show / Hide 
Range on Protein: 201-291
Range on HMM: 213-324/324
Sequence Identity: 24% (28 aa)

YMAPEILK----DKKAHET-SDIWSLGCILYEMCTMK-----ALVSDTLDAASSES----------MLSAILPIR---KLYGYSDVLNDFLNQMLTQNPS
||||.||.     |. ..  .||||||||.||| . |        .|. .    .           .    ....   | .  |. . |.. .||. ...
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEK

LRPDYDTLLNHSRM
 | . . ..||  .
DRISWEEIFNHPWF
Kinase GL50803_14897.AA ULK 201-291 23 9.5e-15 47.99 In-house 217-329 (329) Show / Hide 
Range on Protein: 201-291
Range on HMM: 217-329/329
Sequence Identity: 23% (27 aa)

YMAPEILK----DKKAHET-SDIWSLGCILYEMCT-------MKALVSDTLDAASSES--------MLSAILPIR---KLYGYSDVLNDFLNQMLTQNPS
||||.||.     |. ..  .||||||||.||| .       . .   . .   .           . .  | ..   . .  |. . |.. .||. ...
YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEK

LRPDYDTLLNHSRM
 | . . |.||  .
DRISWEELFNHPWF
Kinase GL50803_14897.AA NEK2 201-230 56 6.9e-14 43.04 In-house 230-259 (319) Show / Hide 
Range on Protein: 201-230
Range on HMM: 230-259/319
Sequence Identity: 56% (17 aa)

YMAPEILKDKKAHETSDIWSLGCILYEMCT
|| || ... |  | |||||.||..||||.
YMSPEQMHGQKYNEKSDIWSVGCLIYEMCA
Kinase GL50803_14897.AA NEK 201-232 58 2e-12 40.45 In-house 190-223 (286) Show / Hide 
Range on Protein: 201-232
Range on HMM: 190-223/286
Sequence Identity: 58% (20 aa)

YMAPEILKDKKAHETSDIWSLGCILYEMCTM--K
||.||....|.  . ||||||||.||||||   |
YMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPK
Kinase GL50803_14897.AA MARK 10-60 34 6.2e-10 28.83 In-house 1-52 (262) Show / Hide 
Range on Protein: 10-60
Range on HMM: 1-52/262
Sequence Identity: 34% (18 aa)

YDILGIIGHGPYATVFKCRHKATEETHIIKEYLLDAIPR-QCISLLRREADL
| .|  |||| ||.| ...|| |..   || |    . . | .. ..||...
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEI
Kinase GL50803_14897.AA CAMK 198-228 34 6.6e-09 24.09 In-house 282-327 (425) Show / Hide 
Range on Protein: 198-228
Range on HMM: 282-327/425
Sequence Identity: 34% (16 aa)

TTAYMA-PEILKD-------------KKAH-ETSDIWSLGCILYEM
| .||| ||.|.              |. . . .|.||.|.||| |
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIM
Kinase GL50803_14897.AA CAMKL 10-65 20 2e-08 22.82 In-house 1-70 (297) Show / Hide 
Range on Protein: 10-65
Range on HMM: 1-70/297
Sequence Identity: 20% (14 aa)

YDILGIIGHGPYATVFKCRH-KATEETHIIKEYLLDAIPRQCISL-------------LRREADLQAQVQ
|.|.  .|.| ...|  ..| . |.|   || .  . |   ....             .|||. .. ...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN
Kinase GL50803_14897.AA MARK 198-228 53 1.4e-07 21.03 In-house 168-199 (262) Show / Hide 
Range on Protein: 198-228
Range on HMM: 168-199/262
Sequence Identity: 53% (17 aa)

TTAYMAPEILKDKKAH-ETSDIWSLGCILYEM
| .||||||.. |.      |||||| .|| |
TPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM
Kinase GL50803_14897.AA NEK 260-291 31 5.6e-07 21.04 In-house 255-286 (286) Show / Hide 
Range on Protein: 260-291
Range on HMM: 255-286/286
Sequence Identity: 31% (10 aa)

YSDVLNDFLNQMLTQNPSLRPDYDTLLNHSRM
||. |.....|||. .|..||. . .|... .
YSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_14897.AA CAMK 15-67 14 7.2e-07 17.41 In-house 1-96 (425) Show / Hide 
Range on Protein: 15-67
Range on HMM: 1-96/425
Sequence Identity: 14% (14 aa)

IIGHGPYATVFKCRHKATE------------ETHIIKEYLLDAIP--------------------------RQCISLLRREADLQAQVQ-----ID
..|.| ...|..|.|| |             .   || .  . ..                           .    .||| ..  ..|     .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLD
Kinase GL50803_14897.AA CAMKL 198-226 46 3e-06 16.01 In-house 196-227 (297) Show / Hide 
Range on Protein: 198-226
Range on HMM: 196-227/297
Sequence Identity: 46% (15 aa)

TTAYMAPEILKD--KKAH-ETSDIWSLGCILY
. .||||||...  |. .    ||||.| |||
SPPYMAPEIFQGNNKPYDGPKVDIWSCGVILY
Kinase GL50803_14897.AA TyrKc 10-291 11 9e-06 -129.62 SMART 1-280 (280) Show / Hide 
Range on Protein: 10-291
Range on HMM: 1-280/280
Sequence Identity: 11% (40 aa)

YDILGIIGHGPYATVFKCRHKATEETHIIKEYLLDAIPRQCISLLRREADLQAQV--QIDSILQPCYTFVDHDS------LVLYIVLPFLGAKTLQAAIE
   . ..|.| . .|.|.. |   ..  .|    ||     .  ..||| .  ..  . . |.. .|  . ...        |.||. .     |.  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVR-LYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SAKTDQTYFTEDVVWSTAYSLLTILKDLASYPLREDDAPSLKPLHCNLKPTNILFLDENLSMVQLCDCSF--------------------------SPDL
. . .                                                      |.| .|.. ..                          . ..
KHRPK------------------------------------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH

----------RLTLSS------TKIGLKAHKRDADHLYTTAYMAPEILKDKKAHETSDIWSLGCILYEMCTMKALVSDT-----LDAASSESMLSAI--L
          |   .       ..   |. ..... .     |||| ....|  . ||.|| |  ..|..|  .          ....     . .   .
TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRM

PIRKLY-------GYSDVLNDFLNQMLTQNPSLRPDYDTLLNHSRM
|. . .         ... .    |    .|. ||   ..  |...
PQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_14897.AA Ciliate-E2-Unclassified 10-40 35 2.5e-05 14.44 In-house 1-31 (352) Show / Hide 
Range on Protein: 10-40
Range on HMM: 1-31/352
Sequence Identity: 35% (11 aa)

YDILGIIGHGPYATVFKCRHKATEETHIIKE
| |. .||.| ...|.||.|| . .  ..|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKY
Kinase GL50803_14897.AA NEK 10-40 27 3.3e-05 14.72 In-house 1-36 (286) Show / Hide 
Range on Protein: 10-40
Range on HMM: 1-36/286
Sequence Identity: 27% (10 aa)

YDILGIIGHGPYATVFKCRHKATEET-----HIIKE
|.|.  || | . .|.|.|.| ..        ..|.
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKK
Kinase GL50803_14897.AA NEK2 10-32 34 4.1e-05 13.04 In-house 1-23 (319) Show / Hide 
Range on Protein: 10-32
Range on HMM: 1-23/319
Sequence Identity: 34% (8 aa)

YDILGIIGHGPYATVFKCRHKAT
|..|. || | . .. | |.| .
YEVLYTIGNGSFGRCRKVRRKSD
Kinase GL50803_14897.AA Ciliate-E2 10-97 14 4.4e-05 13.37 In-house 1-122 (365) Show / Hide 
Range on Protein: 10-97
Range on HMM: 1-122/365
Sequence Identity: 14% (18 aa)

YDILGIIGHGPYATVFKCRHKATEE------------------THIIKEYLLDAIPRQCISLLRREADLQAQVQIDS-----------------ILQPCY
|... .|| | ...|.||... . .                     ||.| .  .  . |  . .| ..  ....                   |..  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

TFVDHDSLVLYIVLPFLGAKTLQ
.| . |   .|.|. ..  ..|.
CFQEKDDNNIYLVMEYCQGGDLF
Kinase GL50803_14897.AA MARK 261-291 29 4.5e-05 12.72 In-house 232-262 (262) Show / Hide 
Range on Protein: 261-291
Range on HMM: 232-262/262
Sequence Identity: 29% (9 aa)

SDVLNDFLNQMLTQNPSLRPDYDTLLNHSRM
|. . ......|| ||. ||... ...|. |
SKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase GL50803_14897.AA Pkinase 10-105 21 7.6e-05 18.21 Pfam 1-101 (293) Show / Hide 
Range on Protein: 10-105
Range on HMM: 1-101/293
Sequence Identity: 21% (22 aa)

YDILGIIGHGPYATVFKCRHKATEETHIIKEYLLDAIPRQCISLLRR--EADLQAQVQIDSILQPCYTFVDHDSLVLYIVLPFLGAK----TLQAAIE-S
| |...|| | ...|.||.|| |...  .|.  .. .  ..   .||  |. . . .. . |..  ..| |.|..   .|.....       | . |. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY--MVMEYCEGGLYVMDLFDYISTW

AKT
...
RHG
Kinase GL50803_14897.AA CAMKL 266-291 38 0.000398 8.9 In-house 272-297 (297) Show / Hide 
Range on Protein: 266-291
Range on HMM: 272-297/297
Sequence Identity: 38% (10 aa)

DFLNQMLTQNPSLRPDYDTLLNHSRM
|.. .||. ||. ||  . ..||  |
DLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase GL50803_14897.AA STE 10-30 28 0.000509 10.23 In-house 1-21 (359) Show / Hide 
Range on Protein: 10-30
Range on HMM: 1-21/359
Sequence Identity: 28% (6 aa)

YDILGIIGHGPYATVFKCRHK
......||.| . ||.|....
WEGIEKIGKGAFGTVYKAMNH
Kinase GL50803_14897.AA NEK2 260-291 28 0.000513 9.28 In-house 288-319 (319) Show / Hide 
Range on Protein: 260-291
Range on HMM: 288-319/319
Sequence Identity: 28% (9 aa)

YSDVLNDFLNQMLTQNPSLRPDYDTLLNHSRM
||. ||.    |.  ... ||  . .| |.. 
YSRHLNEIIHFMINVDHYHRPSIEEILQHPQI
Kinase GL50803_14897.AA CAMK 266-291 34 0.000939 7.18 In-house 400-425 (425) Show / Hide 
Range on Protein: 266-291
Range on HMM: 400-425/425
Sequence Identity: 34% (9 aa)

DFLNQMLTQNPSLRPDYDTLLNHSRM
|....||. .|. |.  .  |||  |
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_14897.AA ULK 10-39 26 0.001301 8.76 In-house 1-34 (324) Show / Hide 
Range on Protein: 10-39
Range on HMM: 1-34/324
Sequence Identity: 26% (9 aa)

YDILGIIGHGPYA-TVFKCRHKATE---ETHIIK
| .  ..|.| .. .|.| |.| |.   .   .|
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACK
Kinase GL50803_14897.AA ULK 10-41 28 0.00545 6.38 In-house 1-30 (329) Show / Hide 
Range on Protein: 10-41
Range on HMM: 1-30/329
Sequence Identity: 28% (9 aa)

YDILGIIGHGPYATVFKCRHKATEETHIIKEY
| .  ..|.| ...|.| |.| |. .  ..|.
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEK
Ank GL50803_14897.AA Ank 404-425 36 0.009695 14.14 Pfam 1-22 (33) Show / Hide 
Range on Protein: 404-425
Range on HMM: 1-22/33
Sequence Identity: 36% (8 aa)

HGKTALMYAAELGRNEFILYLL
.| |.|..|.. |. | . .||
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_14897.AA Ank 434-456 26 4.068214 4.68 Pfam 1-20 (33) Show / Hide 
Range on Protein: 434-456
Range on HMM: 1-20/33
Sequence Identity: 26% (6 aa)

NGATALQLAIAAGNDDGADMIAY
.| |.| ||.  |   ..... .
DGFTPLHLACRCG---HTEVVKM
Ank GL50803_14897.AA Ank 622-654 21 0.007182 14.61 Pfam 1-33 (33) Show / Hide 
Range on Protein: 622-654
Range on HMM: 1-33/33
Sequence Identity: 21% (7 aa)

EGKTALMFCAESNCILMARVLLETEAGLILRDG
.| |.|.  ...... ... ||.  | . ..| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_14897.AA Ank 734-754 47 2.5e-05 23.49 Pfam 1-21 (33) Show / Hide 
Range on Protein: 734-754
Range on HMM: 1-21/33
Sequence Identity: 47% (10 aa)

DGKTALMYAAELGNAEVVQLL
|| |.|..|.. |..|||..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14897.AA Ank 770-792 47 0.001202 17.41 Pfam 1-23 (33) Show / Hide 
Range on Protein: 770-792
Range on HMM: 1-23/33
Sequence Identity: 47% (11 aa)

KGRTALMFACRKNHLNCVFPLLQ
 |.|.|. |||..|...|  |||
DGFTPLHLACRCGHTEVVKMLLQ
Ank GL50803_14897.AA Ank 801-822 40 0.000335 19.41 Pfam 1-22 (33) Show / Hide 
Range on Protein: 801-822
Range on HMM: 1-22/33
Sequence Identity: 40% (9 aa)

RGWTALMMASYLGYTQIIKALL
 |.|.|..|.. |.|...| ||
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_14897.AA Ank 837-860 33 0.002901 16.03 Pfam 1-24 (33) Show / Hide 
Range on Protein: 837-860
Range on HMM: 1-24/33
Sequence Identity: 33% (8 aa)

SGATALMLAAEAGNVAAVSLLVNY
 | |.|.||.. |..  |..|...
DGFTPLHLACRCGHTEVVKMLLQH
Ank GL50803_14897.AA Ank 868-896 44 1e-06 28.25 Pfam 1-29 (33) Show / Hide 
Range on Protein: 868-896
Range on HMM: 1-29/33
Sequence Identity: 44% (13 aa)

NGFTALMMAAQEGHSECVKILMKKEARLN
.|||.|..|.. || |.|| |... | .|
DGFTPLHLACRCGHTEVVKMLLQHGADVN
Ank GL50803_14897.AA Ank 899-924 42 1.3e-05 24.48 Pfam 1-26 (33) Show / Hide 
Range on Protein: 899-924
Range on HMM: 1-26/33
Sequence Identity: 42% (11 aa)

DGWTALMSAVQRNRVECVKLLMAHEA
||.|.|. |......|.||.|. | |
DGFTPLHLACRCGHTEVVKMLLQHGA
Ank GL50803_14897.AA Ank 930-951 45 0.00028 19.69 Pfam 1-22 (33) Show / Hide 
Range on Protein: 930-951
Range on HMM: 1-22/33
Sequence Identity: 45% (10 aa)

SGYTALMCAAQCGWEQCVRMLL
 |.|.|..|..|| ...|.|||
DGFTPLHLACRCGHTEVVKMLL