Gene GL50803_14934 (G.lamblia)

GL50803_14934

Species: G.lamblia
Alias: GL50803_14934, GK190
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_14934.AA Protein None 1510 None Fasta, JSON
GL50803_14934.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of GL50803_14934.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_14934.AA TKL 28-276 18 5.2e-43 149.2 In-house 1-364 (364) Show / Hide 
Range on Protein: 28-276
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)

IGSGGLGDVYRATSAS--------SGVKVAVRRVDISKL----------------------SKEAWAELSTICKPYTNLI---HPNLVRYYSVTIEQPFQ
||||| | ||...           .|  ||| .  .                         ..||. .  .. .    ..   |||.|... . .. |. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

Q-----------LLLEMELCNGGSLQDVIKKMRSDGTSFDEETVWSIASQIAAGLSWLHS--P---FNGVG-VVPHCNIKPSNILIGSQGV---------
.           | . ||.| |||| ...            .   ..| .|| |...|||  |   .      . |...|..|||. . .          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT---KPPIIHRDLKSKNILVDENWTNVSNYMYNP

-----FKLTDFGLQHVPFSRT--------------------IPTSQSGSALYRAPELRDGA---------------SAPSIRSDIWSFGLLLWTMCTLRH
      |..||||  . . ..                       .| |.  . |||. .|.               .  | ..|..|||..|| ..| ..
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

PLFNLD--------------EVTE----EPSIR-----------LPTYSQVLNDLIEGCLRINPTSRLTITEVVSRI
| ....              ..       | |             |.  . . .|.. |   .|..|.. .|...|.
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
S_TKc GL50803_14934.AA S_TKc 22-282 27 2.6e-41 144.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 22-282
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

YNDSSYIGSGGLGDVYRATSASSGVKVAVRRVDISKLSKEAWAELSTICKPYTNLIHPNLVRYYSVTIEQPFQQLLLEMELCNG--GSLQDVIKKMRSDG
|     ||.|. | ||...  ..| .||. ...     . .. |..   |      |||.|..| |  .   . | . ||.|.|  |.| |.|||... |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

TS--FDEETVWSIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGSQGVFKLTDFGLQHVPFSRTIPTSQSGSALYRAPELRDGASAPSI-RSDIWSF
.   |.| ...... ||. .|  .||     |.. |. .||.|||. .  . |..||||  .       |.. |.  |.|||.       .  ..|.||.
LRFPFPE-HARFYMYQICCALEYCHS----HGII-HRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSC

GLLLWTMCTLRHPLFNLDEVTEEPSIRLPTYSQVLNDLIEGCLRINPTSRLTITEVVS---RIRANVPT
| .|. |.. . |.|     ...  ...   |. . |.|..||. .|. |.|. |.      |..    
GCILYEMLC-GYPPFP----QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase GL50803_14934.AA Pkinase 22-276 23 2.6e-39 140.08 Pfam 1-293 (293) Show / Hide 
Range on Protein: 22-276
Range on HMM: 1-293/293
Sequence Identity: 23% (74 aa)

YNDSSYIGSGGLGDVYRATSASSGVKVAVRRVDISKLSKEAW------AELSTICKPYTNLIHPNLVRYYSVTIEQPFQQLLLEMELCNGG----SLQDV
|   . ||||. | ||...  ..| .||| ... .. ... .      .|..       .| ||| ||.| .  .   . . . ||.|.||    .| |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIM----KRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDY

IKKMRSDGTSF--DEETVWSIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGSQGVF----KLTDFGLQHV--PFSRTIPTSQSGSALYRAPELRDG
|.   .....|  .|... ... ||. ||  .||     |.. |. .||.|||| ..|.     |..||||  .    . . .|.  |.  |.|||.  |
IST--WRHGCFYFSEWECKFYMYQILRGLEYCHSM----GII-HRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

ASAPSIRSDIWSFGLLLWTMCTLRHPLFNL----DEVTEEPSIRLPTY------------------------------SQVLNDLIEGCLRINPTSRLTI
..  . ..|.||.|..|. |.. | |  .     . ...   |..  .                              |. . |.|..||. .|..|.|.
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

TEVVSR--I
....    .
EQILQHPWF
Kinase GL50803_14934.AA ULK 22-272 21 2.6e-28 96.01 In-house 1-323 (329) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-323/329
Sequence Identity: 21% (72 aa)

YNDSSYIGSGGLGDVYRAT-SASS---GVKVAVRRVDISKLSKEA--------WAELSTICKPYTNLI--------HPNLVRYYSVTIEQPFQQLLLEME
|. .  .|.|  | ||...   .    ..|||.  .|..|....         |  |   .|    |         ||| |..| .. .. .  . . ||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCNGGSLQDVIKKMRS------DGTSFDEETVWSIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGS------------QGVFKLTDFGLQHVPFSR
.|||| |.. ||| .        .  . |. . ..  ||..|. .||.     ... |. |||.||||              .||.|..|||     |..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK----HNII-HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFG-----FAK

TIP---------TSQS------GSALYRAPELRD---GASAPS-IRSDIWSFGLLLWTMCTLRHP----LFNLD------EVTEEPSIR-----------
..          ....      |. || ||..     .   ..   .||||.| ..  | . . |     . ..      ..  .| ..           
HVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFP

----LPTYSQVLNDLIEGCLRINPTSRLTITEV
     |. |. . ||| ..| .... | ...|.
KDGNDPQISPECKDLIRRMLQYDEKDRISWEEL
Kinase GL50803_14934.AA ULK 22-272 22 2.6e-26 90.39 In-house 1-318 (324) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-318/324
Sequence Identity: 22% (72 aa)

YNDSSYIGSGGLG-DVYRAT-SASS--GVKVAVRRVDISKLSKEA--------WAELSTICKPYTNLI---HPN--LVRYYSVTIEQPFQQLLLEMELCN
|. .  .|.|  |  ||...   .   ...||.  .|..|..|          |  |    .    |    |||   |..| .. .. .  . . ||.||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGSLQDVIKKMRS-----DGTSFDEETVWSIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGS------------QGVFKLTDFGL-QHVP---FSR
|| |.. ||| .       .  . |. . ..  ||..|. .||.     ... |. |||.||||              .||.|..|||. .||    .. 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK----HNII-HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQ

TIPTSQS------GSALYRAPELRD---GASAPS-IRSDIWSFGLLLWTMCTLRHP----LFNLD-------------EVTEEP-SIRLP------TYSQ
.. ...       |. || ||..     .   .. . .||||.| ..  | . . |      ...             .....   |. |        |.
QMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISP

VLNDLIEGCLRINPTSRLTITEV
 . ||| ..| .... | ...|.
ECKDLIRRMLQYDEKDRISWEEI
Kinase GL50803_14934.AA Ciliate-E2 22-272 20 2.6e-26 87.31 In-house 1-359 (365) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-359/365
Sequence Identity: 20% (75 aa)

YNDSSYIGSGGLGDVYRATSASSGV------------------KVAVRRVDISKLSK---EAWAELSTICKPYT-------------NLIHPNLVRYYSV
|.    ||.|. |.||...  . .                   ||..  . .  ..|   |..     |..                .| |||....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TIEQPFQQLLLEMELCNGGSLQDVIKKM---------RSDGTSFDEETVWSIASQIAA---------------GLSWLHSPFNGVGVVPHCNIKPSNILI
 .|.  . . | ||.|.||.|.| ||..           |  .|.|. .  |  ||.                .|  |||  ..   . | .|||.|||.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS--KNN--IIHRDIKPENILF

GSQGVFKLTDFGL-----------------QHVPFSR---TIPTS-------------QSGSALYRAPELRDGAS--------APSIRSDIWSFGLLLWT
      |..||||                 .  .| .   .. ..             . |.. | |||   | .          .  .||||.| .|  
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

MCTLRHPLFNLDEVTE-EPSIRLP-----------------TYSQVLNDLIEG----CLRINPTSRLT-ITEV
|.. ..|   ...  . . ... |                   ||   |||      .|  .|  |.| . ..
MLFGKPPF--QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase GL50803_14934.AA Ciliate-E2-Unclassified 22-272 19 3.9e-26 87.65 In-house 1-346 (352) Show / Hide 
Range on Protein: 22-272
Range on HMM: 1-346/352
Sequence Identity: 19% (68 aa)

YNDSSYIGSGGLGDVYRATSASSGVKV-----AVRRVDISKLSKEA----WAELSTICKP-------YTN-------LIHPNLVRYYSVTIEQPFQQLLL
|.    ||.|| |.||..   . . ..     .    ........     . |. ....        | |       | ||...... . ..|  | . .
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKY-NKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

EMELCNGGSLQDVIKKMRS-------------DGTSFDEETVW-----SIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGSQG---VFKLTDFGL-
 ||.|.||.|.. |||. .              .  |.|. .       .. ||  ||. ||.  .. ... | .|||.|||. ..|     |..|||. 
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHH--KN-NII-HRDIKPENILFDNNGKNYYIKIIDFGIS

---------------QHVPFSRTIPTSQSGSALYR----APELRDG-ASAPS--IRSDIWSFGLLLWTMCTLRHPLFNLDEVT---------------EE
               .   ... . ....|.  |     |||. .|     |  . .||||.| .|  |.. ..| .  ..                 . 
KKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQL

PSIRL---------------PTYSQVLNDLIE----GCLRINPTSRLTITEV
 .. .                . |.   |.|.     .|  || .|.|. ..
YQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Kinase GL50803_14934.AA MLK 22-229 26 2e-24 81.7 In-house 1-235 (291) Show / Hide 
Range on Protein: 22-229
Range on HMM: 1-235/291
Sequence Identity: 26% (64 aa)

YNDSSYIGSGGLGDVYRATSASSGVK-----VAVRRVDISK----LSKEAWAELSTICKPYTNLIHPN----LVRYYSVTIEQPFQQLLLEMELCNGGSL
 . . .||||. |.|....    .       |||.||....     . .   .. . |.    | |||     .. | | ...| ..... || | ||||
IQFHEWIGSGSFGKVWKGRWR--NKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSL

QDVIKKMRSDGT----------SFDEETVWSIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGS------QGVFKLTDFGLQHVPFSR-TIPTSQSG
 .|..  || .             | . . ..| |.| |.. |||  . .  ..|  .|..||||        .|. | .|||. .   .. |  .|. |
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHS--MAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAG

SALYRAPELRD--GASAPSIRSDIWSFGLLLWTMCTLRHP
.. ..||| .    ..  |. .|.||.|..|| | | ..|
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase GL50803_14934.AA STE7-Unclassified 78-271 27 4.5e-21 71.05 In-house 64-293 (301) Show / Hide 
Range on Protein: 78-271
Range on HMM: 64-293/301
Sequence Identity: 27% (66 aa)

HPNLVRYYSVTIEQPFQ-QLLLEMELCNGGSLQ---DVIKKMRS----DGTSFDEETVWSIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGSQGVF
||..|.||   ...    .. . ||.  .|||    |. |||       |. ..| .. .|| |.  ||. ||   . .    |  |||.|||. |.|  
HPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKIDIYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHII----HRDIKPGNILVNSKGQV

KLTDFG----LQHVPFSRTI--PTSQSGSALYRAPELRDGA---SAP-SIRSDIWSFGLLLWTMCTLRHPL--------------------FN-LDEVTE
|..|||    |..     |.   ..  |   | .||   |    ... |..|||||.||..| . |...|.                    .. |. . .
KICDFGVCGQLEN-----TLDEAKTWVGCQMYMSPERIQGQMPHRPSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLSCIVN

EPSIRLPT------YSQVLNDLIEGCLRINPTSRLTITE
.|. |||       .|  . |.|. |. ..|. | .|..
FPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQ
Kinase GL50803_14934.AA STE 22-176 24 5.9e-19 63.65 In-house 1-193 (359) Show / Hide 
Range on Protein: 22-176
Range on HMM: 1-193/359
Sequence Identity: 24% (49 aa)

YNDSSYIGSGGLGDVYRATSA------SSGVK---------VAVRRVDISKLSK---------------EAWAELSTICKPYTNLI--HPNLVRYYSVTI
. . . ||.|. | ||.|         ..| .         .|. ...... ..               | . ..    |   ..   ||| |.||   .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EQP-----FQQLLLEMELCNGGSLQDVIKKMRSDGTSFD----------EETVWSIASQIAAG-LSWLHSPFNGVGVVPHCNIKPSNILIGSQGVFKLTD
         ..| . ||...|||| |.||.  . | ...          |. .  |. ||  | |. |||  ..   . |  |||.|||.      ||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS--HH---IIHRDIKPANILL-----VKLCD

FGL
||.
FGV
Kinase GL50803_14934.AA TyrKc 22-276 23 1.6e-13 -4.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 22-276
Range on HMM: 1-280/280
Sequence Identity: 23% (72 aa)

YNDSSYIGSGGLGDVYRATSASSGVKVAVRRVDISKLSKEAWAELSTICKPYTNL--IHPNLVRYYSVTIEQ--PF---QQLLLEMELCNGGSLQDVIKK
      .|.|  | ||..|     ..|||  .  ..  ..   |..  ||    |   |||.|| | | ..|   |   ..|.. ||.. .|.|.| ..|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCK----LGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

MRSDGTSFDEETVWSIASQIAAGLSWLHSPFNGVGVVPHCNIKPSNILIGSQGVFKLTDFGLQHVPFSRTIPTS-------QSGSA----LYR-------
 | .   .  ..  |.. |||.| . |||     ... |  .   |.|.|.... | .||||     || |          .  ..      .       
HRPK---LCMKDLLSFCWQIACGMEYLHSK----NCI-HRDLAARNCLVGENHTVKISDFGL-----SRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

-APE-LRDGASAPSIRSDIWSFGLLLW---TMCTLRHPL-----FNLDEVTEEPSIR----LPTY---------SQVLNDLIEGCLRINPTSRLTITEVV
 ||| ...|    .. ||.|||| ..|   | .   .|       . .|| |    .     | .         .. . .... | . .| .| | .|..
MAPECINYGKF--TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

SRI
...
ECF
Kinase GL50803_14934.AA NEK 78-143 37 2.6e-13 43.63 In-house 63-132 (286) Show / Hide 
Range on Protein: 78-143
Range on HMM: 63-132/286
Sequence Identity: 37% (26 aa)

HPNLVRYYSVTIEQPFQQLLLEMELCN-GGSLQDV---IKKMRSDGTSFDEETVWSIASQIAAGLSWLHS
||| |.||   ||.  ..|  .|| |. || |..    ||| .  |. |.||..| .  |.. .|  .|.
HPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHD
Kinase GL50803_14934.AA STE 208-271 18 2e-11 36.72 In-house 246-350 (359) Show / Hide 
Range on Protein: 208-271
Range on HMM: 246-350/359
Sequence Identity: 18% (19 aa)

SIRSDIWSFGLLLWTMCTLRHPLFNLDEVTE---------------------EPSIRLPT--------------------YSQVLNDLIEGCLRINPTSR
....||||.|.... |.| ..|....                          .|. .||.                    .|. ..| |. ||...|  |
DTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKR

LTITE
 | ..
PTASQ
Kinase GL50803_14934.AA NAK 78-144 29 1e-10 31.91 In-house 66-138 (299) Show / Hide 
Range on Protein: 78-144
Range on HMM: 66-138/299
Sequence Identity: 29% (22 aa)

HPNLVRYYSVTIEQP------FQQLLLEMELCNGGSLQDVIKKMRS-DGTSFDEETVWSIASQIAAGLSWLHSP
|.|.|.|..  |...      ....|| ||.| .|||.|.. |... .|| | |. .. | .... |.. .|..
HNNIVQYIDSHINERDDSNGTWEVFLL-MEYCCHGSLWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQC
Kinase GL50803_14934.AA NAK 245-276 34 4.6e-10 29.69 In-house 268-299 (299) Show / Hide 
Range on Protein: 245-276
Range on HMM: 268-299/299
Sequence Identity: 34% (11 aa)

PTYSQVLNDLIEGCLRINPTSRLTITEVVSRI
..||| ..||| ..|...|  |..| .|....
SRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase GL50803_14934.AA Pkinase_Tyr 78-143 33 6.7e-08 27.39 Pfam 63-129 (270) Show / Hide 
Range on Protein: 78-143
Range on HMM: 63-129/270
Sequence Identity: 33% (23 aa)

HPNLVRYYSVTI--EQPFQQLLLEMELCNGGSLQDVIKKMRSDGTSFDEETVWSIASQIAAGLSWLHS
|||.||.| | .  ..|  |... ||.. .|.| |  .| |.|. ... ..  ... |||.|...|.|
HPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase GL50803_14934.AA NEK 243-278 25 6e-06 17.31 In-house 248-286 (286) Show / Hide 
Range on Protein: 243-278
Range on HMM: 248-286/286
Sequence Identity: 25% (10 aa)

RLP-T--YSQVLNDLIEGCLRINPTSRLTITEVVSRIRA
..| .  ||| |..||. .|. .|..| ..... ..   
PIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_14934.AA NAK 156-175 47 7.7e-05 11.99 In-house 149-171 (299) Show / Hide 
Range on Protein: 156-175
Range on HMM: 149-171/299
Sequence Identity: 47% (11 aa)

IKPSNILIGS---QGVFKLTDFG
||. |||...   .| .|| |||
IKIENILLSESHHDGNYKLCDFG
Kinase GL50803_14934.AA NEK 210-229 59 0.000233 11.71 In-house 204-225 (286) Show / Hide 
Range on Protein: 210-229
Range on HMM: 204-225/286
Sequence Identity: 59% (13 aa)

RSDIWSFGLLLWTMCTL--RHP
.|||||.| .|  ||||  .||
KSDIWSLGCVLYEMCTLKPKHP
Kinase GL50803_14934.AA NAK 192-224 42 0.000236 10.35 In-house 201-235 (299) Show / Hide 
Range on Protein: 192-224
Range on HMM: 201-235/299
Sequence Identity: 42% (15 aa)

SALYRAPELRDGASAPSI--RSDIWSFGLLLWTMC
.  |||||. |  |   |  ..|||. | .| .||
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMC
Kinase GL50803_14934.AA NEK 156-176 36 0.018878 4.91 In-house 145-169 (286) Show / Hide 
Range on Protein: 156-176
Range on HMM: 145-169/286
Sequence Identity: 36% (9 aa)

IKPSNILIGSQGV----FKLTDFGL
|||.|| . ...      |. |||.
IKPQNIFLTKNNNDYHNVKIGDFGI
Kinase GL50803_14934.AA Pkinase_Tyr 208-221 57 0.020244 8.82 Pfam 192-205 (270) Show / Hide 
Range on Protein: 208-221
Range on HMM: 192-205/270
Sequence Identity: 57% (8 aa)

SIRSDIWSFGLLLW
.. ||.|||| |.|
TTKSDVWSFGVLMW
Kinase GL50803_14934.AA Pkinase_Tyr 160-176 47 1.86119 2.17 Pfam 141-157 (270) Show / Hide 
Range on Protein: 160-176
Range on HMM: 141-157/270
Sequence Identity: 47% (8 aa)

NILIGSQGVFKLTDFGL
|.|.....| | .||||
NCLVTENNVVKICDFGL
Kinase GL50803_14934.AA Pkinase_Tyr 251-276 26 2.579324 1.69 Pfam 245-270 (270) Show / Hide 
Range on Protein: 251-276
Range on HMM: 245-270/270
Sequence Identity: 26% (7 aa)

LNDLIEGCLRINPTSRLTITEVVSRI
. ||.  | . .|  | | .|.....
IYDLMKQCWHYDPEDRPTFSEIHEQL
Ank GL50803_14934.AA Ank 700-729 30 1.3e-05 24.53 Pfam 1-33 (33) Show / Hide 
Range on Protein: 700-729
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

KNRTALMLAAEHGSVECIKLLLG---ELAIQNS
  .|.|.||...|..|..|.||.   .. .|. 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_14934.AA Ank 730-750 33 0.008533 14.34 Pfam 1-21 (33) Show / Hide 
Range on Protein: 730-750
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

MGETALVLAAKKGYVDCISLL
.|.|.| ||...|.......|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14934.AA Ank 771-791 28 5.119167 4.32 Pfam 1-21 (33) Show / Hide 
Range on Protein: 771-791
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

SGLTPLMASIRSGQRHCIHEF
 | |||.  .|.|.  .. ..
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14934.AA Ank 801-830 18 6.693005 3.9 Pfam 1-33 (33) Show / Hide 
Range on Protein: 801-830
Range on HMM: 1-33/33
Sequence Identity: 18% (6 aa)

NGATSLMYAVLGELDACIPYLVD---ECRITDN
.| | |..|..     .. .|..   .  ..|.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_14934.AA Ank 831-851 28 25.558155 1.8 Pfam 1-21 (33) Show / Hide 
Range on Protein: 831-851
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

LGESALMKAVDGPSMQVVEFL
 |...|. |.   ...||..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14934.AA Ank 862-883 31 11.223329 3.09 Pfam 1-22 (33) Show / Hide 
Range on Protein: 862-883
Range on HMM: 1-22/33
Sequence Identity: 31% (7 aa)

EGRTALLRAIQNKNVTYVKAML
.|.|.|  |... ..  ||  |
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_14934.AA Ank 900-920 28 76.469936 0.08 Pfam 1-21 (33) Show / Hide 
Range on Protein: 900-920
Range on HMM: 1-21/33
Sequence Identity: 28% (6 aa)

DGTTLFTAAIKSGSENLIYLL
|| |    |...|... . .|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_14934.AA Ank 1035-1053 36 0.003275 15.84 Pfam 1-19 (33) Show / Hide 
Range on Protein: 1035-1053
Range on HMM: 1-19/33
Sequence Identity: 36% (7 aa)

DGYTALMIAAINGNQAFVE
||.|.|..|...|.   |.
DGFTPLHLACRCGHTEVVK
Ank GL50803_14934.AA Ank 1071-1092 22 32.358818 1.43 Pfam 1-22 (33) Show / Hide 
Range on Protein: 1071-1092
Range on HMM: 1-22/33
Sequence Identity: 22% (5 aa)

EGRSALILSILHQRVACAKILV
.|...| | ... .. ..| |.
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_14934.AA Ank 1104-1126 43 0.846048 7.14 Pfam 1-23 (33) Show / Hide 
Range on Protein: 1104-1126
Range on HMM: 1-23/33
Sequence Identity: 43% (10 aa)

DGVTPLILAIQKRFYSIVPSLLE
|| ||| ||...  ...|  ||.
DGFTPLHLACRCGHTEVVKMLLQ
Ank GL50803_14934.AA Ank 1134-1146 23 70.847116 0.2 Pfam 1-13 (33) Show / Hide 
Range on Protein: 1134-1146
Range on HMM: 1-13/33
Sequence Identity: 23% (3 aa)

EGKSALMIAMELN
.| ..|..| . .
DGFTPLHLACRCG
Ank GL50803_14934.AA Ank 1346-1367 50 2e-06 27.28 Pfam 1-22 (33) Show / Hide 
Range on Protein: 1346-1367
Range on HMM: 1-22/33
Sequence Identity: 50% (11 aa)

NGRTALMLAAQNGHLECVHLLL
.|.|.|.||...||.|.| .||
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_14934.AA Ank 1316-1345 30 2.1e-05 23.74 Pfam 1-33 (33) Show / Hide 
Range on Protein: 1316-1345
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

NGRTALMEAAARGYASCVRLLLG---EVGFRDE
.|.|.|. |. .|....|..||.   .|  .| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_14934.AA Ank 1376-1397 36 9.941801 3.28 Pfam 1-22 (33) Show / Hide 
Range on Protein: 1376-1397
Range on HMM: 1-22/33
Sequence Identity: 36% (8 aa)

TRETALTLAVANDMTECADVLL
  .|.| ||. .. ||..  ||
DGFTPLHLACRCGHTEVVKMLL
Zf-C3HC4 GL50803_14934.AA zf-C3HC4 1449-1494 27 4e-07 21.64 Pfam 1-48 (48) Show / Hide 
Range on Protein: 1449-1494
Range on HMM: 1-48/48
Sequence Identity: 27% (15 aa)

CHICLDELCTVR---CLPCSHD----VACPSCVRDILEATRAGNTKRNR-CPIC
|.||..|. .      .|| |     . | ||.. ...       ..|. ||||
CWICHCEWKDPNNPLIHPCGHRGSLKWFCHSCIKRWWNH------SGNTQCPIC
RING GL50803_14934.AA RING 1449-1494 30 8e-06 26.68 SMART 1-23 (23) Show / Hide 
Range on Protein: 1449-1494
Range on HMM: 1-23/23
Sequence Identity: 30% (14 aa)

CHICLDELCTVRCLPCSHDVACPSCVRDILEATRAGNTKRNRCPIC
|.|||.    ...||| |   |  |.                ||||
CPICLE----PVVLPCGH--FCY-CI----------------CPIC