Gene GL50803_15064 (G.lamblia)
GL50803_15064
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_15064.AA | Protein | None | 564 | None | Fasta, JSON |
| GL50803_15064.kin_dom | Protein Kinase Domain | None | 259 | None | Fasta, JSON |
Protein domains of GL50803_15064.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | GL50803_15064.AA | S_TKc | 35-293 | 18 | 2.4e-13 | 18.84 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 35-293 Range on HMM: 1-231/231 Sequence Identity: 18% (53 aa) YQLKEVVNRGTFRTTYRVYDNQSGEHLYCKRLDASNMPASQLSAFVSNMMSISALQEKGYLA------IDTVFVLAKRKLAYIVTPDFGDC---SLAHLI |.. ... .|.| . |..... .|.. .|... .....| | . | . |.|. .. | .| ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVM-EYCDGDLGDLFDYI HTARRQQTS--FEESLVWRVLAQIAAKLYALHFPGEHGIRPGRRFIHCQLKPSNIFLSQALTVFIVDPLGVAFSSYCWANSDDDGFRYIPNEALTAATLT . .|. . | | ......||. | .| ...||. |||.||.|.. .. | | |.| .. |.. | | . KKRGRHGLRFPFPE-HARFYMYQICCALEYCH---------SHGIIHRDLKPENILLDE--HIKICD-FGLARQL----TTFCGTPWYMAPEVL---GYG S-KIDIYSLGCVLYELCT---LFSRTFHESPVDYVTLLRETHYSSQLKDLVLAMLSPYPDARPSAQDLMH-------NTTI |.|..|.||.|||... .|. .. .... |...||.. .| |. ||.| .... . KCKCDWWSCGCILYEMLCGYPPFP--------QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | GL50803_15064.AA | NEK2 | 121-183 | 26 | 1.9e-09 | 27.82 | In-house | 87-161 (319) | Show / Hide |
Range on Protein: 121-183 Range on HMM: 87-161/319 Sequence Identity: 26% (20 aa) LAHLIHTARRQQTSFEESLVWRVLAQIAAKLYALHF----PGEHGI-------RPG-RRFIHCQLKPSNIFLSQA |. .| .| . . .||. .||...|. |. | | | .| . .| .|| ||||... LSQMIKKCRKERQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYD |
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| Kinase | GL50803_15064.AA | TKL | 169-291 | 14 | 1.1e-08 | 27.39 | In-house | 162-364 (364) | Show / Hide |
Range on Protein: 169-291 Range on HMM: 162-364/364 Sequence Identity: 14% (29 aa) IHCQLKPSNIFLSQALTV-------------FIVDPLGVAF------SSYCWA--------------NSDDDG--FRYIPNEALTAA------------- ||. ||..||.. . .|. . .| . .. ... .. . .|. . |.| . IHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFC ---TLTSKIDIYSLGCVLYELCT--LFSRTFHES------------PVDYVTLLR---------------ETHYSSQLKDLVLAMLSPYPDARPSAQDLM . . |.|.|| | ||.|..| . . .... .... || ... ..|.| .. |..|||.|... KGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEIL HNT . KRL |
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| Kinase | GL50803_15064.AA | PEK | 223-293 | 28 | 3.4e-08 | 23.85 | In-house | 572-655 (655) | Show / Hide |
Range on Protein: 223-293 Range on HMM: 572-655/655 Sequence Identity: 28% (24 aa) TSKIDIYSLGCVLYELCTLFSRTFHESPVDYVTLLRE--------------THYSSQLKDLVLAMLSPYPDARPSAQDLMHNTTI . |.|.|||| .. |.. |. | .| |. | || . ...|... |||. |. |||||... . .. NHKVDMYSLGIIFFEMWYPFFTTMMER-VKTLTDLRDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF |
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| Kinase | GL50803_15064.AA | WEE | 262-293 | 34 | 5.7e-08 | 22.89 | In-house | 266-297 (297) | Show / Hide |
Range on Protein: 262-293 Range on HMM: 266-297/297 Sequence Identity: 34% (11 aa) YSSQLKDLVLAMLSPYPDARPSAQDLMHNTTI .|. ||.|. |. |.|. ||..|.|. . . ISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL |
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| Kinase | GL50803_15064.AA | NEK | 261-293 | 34 | 8e-07 | 20.48 | In-house | 252-286 (286) | Show / Hide |
Range on Protein: 261-293 Range on HMM: 252-286/286 Sequence Identity: 34% (12 aa) H--YSSQLKDLVLAMLSPYPDARPSAQDLMHNTTI | ||..|..|. || . |. |||..... . | HRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | GL50803_15064.AA | IRE | 211-236 | 37 | 1e-06 | 18.3 | In-house | 195-223 (292) | Show / Hide |
Range on Protein: 211-236 Range on HMM: 195-223/292 Sequence Identity: 37% (11 aa) YIPNEALTA---ATLTSKIDIYSLGCVLY ..| | |. . .|...|| |.|||.| WHPPEMLQEFCQKRKTKSVDIFSMGCVFY |
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| Kinase | GL50803_15064.AA | Pkinase | 223-289 | 16 | 1e-06 | 24.58 | Pfam | 190-289 (293) | Show / Hide |
Range on Protein: 223-289 Range on HMM: 190-289/293 Sequence Identity: 16% (16 aa) TSKIDIYSLGCVLYELCTLFSRTFHE--------SPVDYVTLLRETHYS-------------------------SQLKDLVLAMLSPYPDARPSAQDLMH ..|.|..|.||.|||... .. . . .. ...|.. . .||.. .| . | ||.|..... GPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ |
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| Kinase | GL50803_15064.AA | NEK1 | 225-241 | 88 | 1e-06 | 19.09 | In-house | 201-217 (276) | Show / Hide |
Range on Protein: 225-241 Range on HMM: 201-217/276 Sequence Identity: 88% (15 aa) KIDIYSLGCVLYELCTL | || |||||||||||| KSDIWSLGCVLYELCTL |
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| Kinase | GL50803_15064.AA | NEK8 | 227-241 | 66 | 1e-06 | 14.64 | In-house | 204-218 (278) | Show / Hide |
Range on Protein: 227-241 Range on HMM: 204-218/278 Sequence Identity: 66% (10 aa) DIYSLGCVLYELCTL |. .|||||||.|.| DMWALGCVLYEMCCL |
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| Kinase | GL50803_15064.AA | NEK1 | 261-293 | 36 | 1.5e-05 | 15.45 | In-house | 244-276 (276) | Show / Hide |
Range on Protein: 261-293 Range on HMM: 244-276/276 Sequence Identity: 36% (12 aa) HYSSQLKDLVLAMLSPYPDARPSAQDLMHNTTI ||| |. || |.. | |||.... | HYSYELQSLVSQMFKRNPRHRPSVNQILERPFI |
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| Kinase | GL50803_15064.AA | NEK2 | 227-241 | 60 | 2.6e-05 | 13.69 | In-house | 246-260 (319) | Show / Hide |
Range on Protein: 227-241 Range on HMM: 246-260/319 Sequence Identity: 60% (9 aa) DIYSLGCVLYELCTL || |.||..||.|.| DIWSVGCLIYEMCAL |
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| Kinase | GL50803_15064.AA | NEK8 | 261-293 | 36 | 4.3e-05 | 10.36 | In-house | 246-278 (278) | Show / Hide |
Range on Protein: 261-293 Range on HMM: 246-278/278 Sequence Identity: 36% (12 aa) HYSSQLKDLVLAMLSPYPDARPSAQDLMHNTTI |||. .. ||.. |. |. |||| .| . . HYSNEMRMLVHNCLQQDPEQRPSASQIMAMPLC |
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| Kinase | GL50803_15064.AA | NAK | 262-291 | 36 | 0.000139 | 11.13 | In-house | 270-299 (299) | Show / Hide |
Range on Protein: 262-291 Range on HMM: 270-299/299 Sequence Identity: 36% (11 aa) YSSQLKDLVLAMLSPYPDARPSAQDLMHNT ||.|..||. .|| | |. ||. .. . . YSQQMHDLIRYMLTPDPEQRPNIYQVLNQL |
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| Kinase | GL50803_15064.AA | NEK-Unclassified | 262-293 | 31 | 0.000241 | 9.95 | In-house | 227-258 (258) | Show / Hide |
Range on Protein: 262-293 Range on HMM: 227-258/258 Sequence Identity: 31% (10 aa) YSSQLKDLVLAMLSPYPDARPSAQDLMHNTTI || | ... || .. |||| ... | YSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI |
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| Kinase | GL50803_15064.AA | NAK | 221-239 | 47 | 0.000258 | 10.22 | In-house | 217-235 (299) | Show / Hide |
Range on Protein: 221-239 Range on HMM: 217-235/299 Sequence Identity: 47% (9 aa) TLTSKIDIYSLGCVLYELC . ..|.|| .|||.|| .| PIDEKVDIWALGCMLYKMC |
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| Kinase | GL50803_15064.AA | WEE | 209-240 | 40 | 0.00031 | 10.19 | In-house | 197-231 (297) | Show / Hide |
Range on Protein: 209-240 Range on HMM: 197-231/297 Sequence Identity: 40% (14 aa) FRYIPNEALT---AATLTSKIDIYSLGCVLYELCT .||...| | .| | ||.|||...||| . SRYMAPEILQGYYHYTHLYKADIFSLGITIYELAC |
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| Kinase | GL50803_15064.AA | NEK | 230-241 | 91 | 0.000391 | 10.91 | In-house | 209-220 (286) | Show / Hide |
Range on Protein: 230-241 Range on HMM: 209-220/286 Sequence Identity: 91% (11 aa) SLGCVLYELCTL ||||||||.||| SLGCVLYEMCTL |
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| Kinase | GL50803_15064.AA | NEK-Unclassified | 227-240 | 64 | 0.002039 | 6.83 | In-house | 179-192 (258) | Show / Hide |
Range on Protein: 227-240 Range on HMM: 179-192/258 Sequence Identity: 64% (9 aa) DIYSLGCVLYELCT |. ||||..||.|| DVWSLGCIIYEMCT |
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| Kinase | GL50803_15064.AA | NEK-Unclassified | 166-186 | 57 | 0.00252 | 6.52 | In-house | 116-136 (258) | Show / Hide |
Range on Protein: 166-186 Range on HMM: 116-136/258 Sequence Identity: 57% (12 aa) RRFIHCQLKPSNIFLSQALTV |. || |||.|||| . .|| RKIIHRDLKPQNIFLTDDDTV |
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| Kinase | GL50803_15064.AA | NEK2 | 262-293 | 25 | 0.004309 | 6.12 | In-house | 288-319 (319) | Show / Hide |
Range on Protein: 262-293 Range on HMM: 288-319/319 Sequence Identity: 25% (8 aa) YSSQLKDLVLAMLSPYPDARPSAQDLMHNTTI ||. | ... |. . ||| .. . | YSRHLNEIIHFMINVDHYHRPSIEEILQHPQI |
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| Kinase | GL50803_15064.AA | PEK | 168-182 | 66 | 0.017951 | 3.55 | In-house | 448-462 (655) | Show / Hide |
Range on Protein: 168-182 Range on HMM: 448-462/655 Sequence Identity: 66% (10 aa) FIHCQLKPSNIFLSQ .|| .||||||||.. MIHRDLKPSNIFLDC |
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| Kinase | GL50803_15064.AA | IRE | 267-285 | 31 | 0.061402 | 2.01 | In-house | 266-284 (292) | Show / Hide |
Range on Protein: 267-285 Range on HMM: 266-284/292 Sequence Identity: 31% (6 aa) KDLVLAMLSPYPDARPSAQ .||. .|....|. ||... CDLIHQMIHHDPQKRPTIK |
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| Kinase | GL50803_15064.AA | NEK1 | 166-181 | 43 | 0.195173 | 0.95 | In-house | 123-138 (276) | Show / Hide |
Range on Protein: 166-181 Range on HMM: 123-138/276 Sequence Identity: 43% (7 aa) RRFIHCQLKPSNIFLS |. .| .|..||||. RKILHRDIKSQNIFLT |
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| Kinase | GL50803_15064.AA | NEK | 121-148 | 22 | 0.240896 | 0.97 | In-house | 94-124 (286) | Show / Hide |
Range on Protein: 121-148 Range on HMM: 94-124/286 Sequence Identity: 22% (7 aa) LAHL---IHTARRQQTSFEESLVWRVLAQIA |. . | . . . |||. .|....|.. LYQKIKSIKKQKQKGKYFEEEQIWDWFIQMC |
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| Pkinase | GL50803_15064.AA | Pkinase | 115-182 | 21 | 2.744112 | 2.1 | Pfam | 80-143 (293) | Show / Hide |
Range on Protein: 115-182 Range on HMM: 80-143/293 Sequence Identity: 21% (16 aa) DFGDC-----SLAHLIHTARRQQTSF--EESLVWRVLAQIAAKLYALHFPGEHGIRPGRRFIHCQLKPSNIFLSQ .. .. .|...|.| .....| .| . ... ||. |. .| ..||. |||.||.... EYCEGGLYVMDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDN |
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