Gene GL50803_15338 (G.lamblia)
GL50803_15338
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_15338.AA | Protein | None | 385 | None | Fasta, JSON |
| GL50803_15338.kin_dom | Protein Kinase Domain | None | 283 | None | Fasta, JSON |
Protein domains of GL50803_15338.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | GL50803_15338.AA | S_TKc | 86-364 | 13 | 7e-06 | -90.78 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 86-364
Range on HMM: 1-231/231
Sequence Identity: 13% (44 aa)
STLINICG-------YLATECRAITSKEGENVQIHVLLLEKVPVHIRNLILYEYEMYSELQCPHMLQILSAKLMPEHSLLLIETRMCYGITLASLMHMHR
..... | |.... . |. | | .. . |. | .. .. ..|. ... . .| . | . .| .... ..
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG
QAA--VSIPEEFIWFLLVAVAEMLAELHD--------------FTTRSEIERRCHFVTPYNIFLS---VAGKVHIFPATESLSSVMCYGQQSYLAPELLG
. .|| ..|.. ... |. .|. ... .| .. .| .. . .| |.|||.|
RHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------------HIKICDFGLARQL----------TTFCGTPW-YMAPEVL-
SSTMQVTP-QSDIWSLGKLLSDMCLLLLPSSPEPPSLPTDTDIFTVPGIPGQQFTYSDDHACLDSRFNSQASAHPCYSLLLTIIIGKCMSPDPQDRPLAE
. .. .|.||.| .| |. | . .. .| . | | . .| ||. ||..|| |
----GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPEKRPTA-
ELLG---------FL
|.| ..
EALQDEWDIKCHPWF
|
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| Kinase | GL50803_15338.AA | AGC | 252-275 | 38 | 9e-06 | 9.39 | In-house | 273-292 (395) | Show / Hide |
Range on Protein: 252-275 Range on HMM: 273-292/395 Sequence Identity: 38% (10 aa) YLAPELLGSSTMQVTPQSDIWS--LG |.||| | ... |.|| || YMAPEIL------YGKACDWWSFGLG |
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| Kinase | GL50803_15338.AA | RSKL | 252-278 | 37 | 5.2e-05 | 6.27 | In-house | 344-368 (436) | Show / Hide |
Range on Protein: 252-278 Range on HMM: 344-368/436 Sequence Identity: 37% (10 aa) YLAPELLGSSTMQVTPQSDIWSLGKLL | ||| .. .|. .|.||.| .| YCAPEV--GQIWELTEACDWWSYGAVL |
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| Kinase | GL50803_15338.AA | C8 | 248-278 | 35 | 0.000107 | 12.35 | In-house | 193-226 (226) | Show / Hide |
Range on Protein: 248-278 Range on HMM: 193-226/226 Sequence Identity: 35% (12 aa) GQQSYLAPELLGS---STMQVTPQSDIWSLGKLL | . |.||| . | . |||..|.| .| GTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL |
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| Kinase | GL50803_15338.AA | UTK | 345-364 | 40 | 0.000185 | 11.17 | In-house | 277-296 (296) | Show / Hide |
Range on Protein: 345-364 Range on HMM: 277-296/296 Sequence Identity: 40% (8 aa) KCMSPDPQDRPLAEELLGFL .|. .|||.|| .|.|. .. RCWHYDPQERPDFEDLVQQM |
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| Kinase | GL50803_15338.AA | TKL | 342-364 | 34 | 0.00029 | 11.27 | In-house | 342-364 (364) | Show / Hide |
Range on Protein: 342-364 Range on HMM: 342-364/364 Sequence Identity: 34% (8 aa) IIGKCMSPDPQDRPLAEELLGFL .. .|...||..|| ..|.| | LMQDCWDHDPEKRPSFQEILKRL |
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| Kinase | GL50803_15338.AA | Pkinase | 252-364 | 22 | 0.000376 | 15.76 | Pfam | 177-293 (293) | Show / Hide |
Range on Protein: 252-364 Range on HMM: 177-293/293 Sequence Identity: 22% (27 aa) YLAPELLGSSTMQVTPQSDIWSLGKLLSDMCLLLLPSSPEPPSLPTDTDIFTVPGIPGQQFTYSDDHACLDSRFNSQAS------AHPCYSLLLTIIIGK |.|||.. . .| .|.||.| .| |.. .| . .. ....... . | | .. .. . | |.|. . | . .| . YMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWHFHWTF-HNWSEECKDFIKW CMSPDPQDRPLAEELLGF--L | .||..|| ||..| . CLCKDPKKRPTAEQILQHPWF |
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| Kinase | GL50803_15338.AA | TK | 334-364 | 20 | 0.000386 | 8.93 | In-house | 443-486 (486) | Show / Hide |
Range on Protein: 334-364 Range on HMM: 443-486/486 Sequence Identity: 20% (9 aa) CYS-------------LLLTIIIGKCMSPDPQDRPLAEELLGFL | . .. ... .| ..||.||| ..|. .| CPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL |
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| Kinase | GL50803_15338.AA | Ciliate-E6 | 252-275 | 25 | 0.000601 | 8.86 | In-house | 123-154 (154) | Show / Hide |
Range on Protein: 252-275 Range on HMM: 123-154/154 Sequence Identity: 25% (8 aa) YLAPELLG--------SSTMQVTPQSDIWSLG |..||.. . | .||||.. YCPPEQFDYSKDQQSKHYKVNWTQEGDIWSVC |
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| Kinase | GL50803_15338.AA | PEK | 342-364 | 40 | 0.000667 | 8.62 | In-house | 631-655 (655) | Show / Hide |
Range on Protein: 342-364 Range on HMM: 631-655/655 Sequence Identity: 40% (10 aa) IIGKCMSPDPQDRPLAEELL--GFL .| ...|.|||.|| |...| .|. FIQWMLSHDPQQRPSAQQILQHEFF |
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| Kinase | GL50803_15338.AA | MEK1 | 248-281 | 47 | 0.000991 | 8.04 | In-house | 158-189 (297) | Show / Hide |
Range on Protein: 248-281 Range on HMM: 158-189/297 Sequence Identity: 47% (16 aa) GQQSYLAPELLGSSTMQVTPQSDIWSLGKLLSDM | ||..|| | . | ||||||.| | .| GTRSYMSPERLQGTHYTV--QSDIWSMGLSLVEM |
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| Kinase | GL50803_15338.AA | TKL | 248-275 | 19 | 0.026058 | 4.14 | In-house | 235-276 (364) | Show / Hide |
Range on Protein: 248-275 Range on HMM: 235-276/364 Sequence Identity: 19% (8 aa) GQQSYLAPELLGSSTM--------------QVTPQSDIWSLG | ..|||.| .. . ....|..| | GTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFG |
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| Kinase | GL50803_15338.AA | TK | 252-275 | 32 | 0.049124 | 1.75 | In-house | 351-381 (486) | Show / Hide |
Range on Protein: 252-275 Range on HMM: 351-381/486 Sequence Identity: 32% (10 aa) YLAPELLGSS-------TMQVTPQSDIWSLG ..||| | . . |..||.||.| WMAPECLNDRVFSEAEKYGKFTTKSDVWSFG |
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