Gene GL50803_16235 (G.lamblia)

GL50803_16235

Species: G.lamblia
Alias: GL50803_16235, GK017
External Links: GiardiaDB ,
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CIPK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_16235.AA Protein None 403 None Fasta, JSON
GL50803_16235.kin_dom Protein Kinase Domain None 280 None Fasta, JSON

Protein domain

Protein domains of GL50803_16235.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_16235.AA CAMK 79-353 23 2.1e-98 317.71 In-house 1-425 (425) Show / Hide 
Range on Protein: 79-353
Range on HMM: 1-425/425
Sequence Identity: 23% (104 aa)

VLGRGTYATVKLATDSRTK------------EEVAIKIITKSGQL-------------------------TKKQLKHIRTEIVVLRL-------VSHPNI
.||||....|||... .|.            ..|||||| |.                            . | .| .| || ....       ..||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLKEILAS-------------------KNKIYIVM---EYLEGG----DILTALREN--------------D--FTIEQVRRYFIQICSALEYCQKLHI
.|| |.  .                   ....|.||   || .||    |..  ..|.              .  || ...|||| |||||..|| ...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

SHRDIKAENLLLRKGR----------------QSVVITDFGLSALTEDAE-------DDDGQGGGEQKAPGTRGS-------KLLTTACGSPHYVS-PEV
 |||.| ||.|| .                    . |.|||...  .. |        ..|.   ..       .       ....| ||.|.|.. |||
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN-------QWTTPTEGQKMKTFCGTPEYMAAPEV

VSK-----------TNVGYFGEKADIWSVGVLLYLMLGRTLPFQAN-------------TLEALFERIRTGQFSFPEDRVK-------------------
...            .  | |.|.|.||.||.|| ||  ..||..              ... |||.|..|...||.. ..                   
LNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFH

KGYFTKESMGLIISMLNIDPAKRPSFTQILESDYV
. ....| . || .||. || ||.. .|.|.   .
H-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_16235.AA CAMKL 74-353 33 1.8e-96 308.36 In-house 1-297 (297) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-297/297
Sequence Identity: 33% (105 aa)

YEVTGVLGRGTYATVKLATD-SRTKEEVAIKIITKSGQL-TKKQLKH-----------IRTEIVVLRLVS---HPNIVKLKEILASKNK------IYIVM
|..  .||.|....|||||. . |.|.|||||| |..     . .|.           || ||  .....   ||||.|| |..  ...      ||.||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYLEGGD--ILTALREND-----FTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLR-KGRQSVVITDFGLSALTEDAEDDDGQGGGEQKAPGTRG
|| .||.   .  ....      .. .. |||| ||.||..|| ...| |||||.||.||  .|.. . |.|||.|.. ..                  |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC---------------IFG

-SKLLTTACGSPHYVSPEVVSKTNVGYFGEKADIWSVGVLLYLMLGRTLPFQANTLE-------ALFERIRTGQFSFPEDRVKKGYFTKESMGLIISMLN
  ..|.| ||||.| .||.....|  | | |.|||| ||.|| |.  .||| . |..        |...|..| . .|    .  .   .   || .||.
PGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPP----IWYHVS-DCRDLIRKMLQ

IDPAKRPSFTQILESDYV
 .| |||.  ||..   .
VNPEKRPTIHQIMNHPWM
S_TKc GL50803_16235.AA S_TKc 74-353 30 1.4e-92 314.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-231/231
Sequence Identity: 30% (90 aa)

YEVTGVLGRGTYATVKLATDSRTKEEVAIKIITKSGQLTKKQLKHIRTEIVVLRLVSHPNIVKLKEILASKNKIYIVMEYLEG--GDILTALREND----
||.  ..|.|....|..... .|...||||||           .||| || .|.   |||||||...  . ...|.||||..|  || .. ....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQSVVITDFGLSALTEDAEDDDGQGGGEQKAPGTRGSKLLTTACGSPHYVSPEVVSK
   |.  ..|.|. |||.||||| ...| |||.| ||.|| .    . |.||||...                          || ||.|.|..|||.  
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL-------------------------TTFCGTPWYMAPEVL--

TNVGYFGE-KADIWSVGVLLYLMLGRTLPFQANTLEALFERIRTGQFSFPEDRVKKGYFTKESMGLIISMLNIDPAKRPSFTQILE-------SDYV
     .|  |.|.||.|..|| || .  ||.  .....|..|.                ..|   .|  .|. ||.|||.  ..|.         ..
----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_16235.AA AGC 74-353 21 1.6e-86 222.99 In-house 1-395 (395) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-395/395
Sequence Identity: 21% (89 aa)

YEVTGVLGRGTYATVKLATDS------RTKEEVAIKIITKSG-QLTKK--QLKHIRTE------------IVVLRLVS----------HPNIVK-LKEIL
.|.  |.|.|.. .| |. .        |..  |.|.. |.   . ||  ...|. ||              .| ...          ||.||| |.   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ASKNK--IYIVMEYLE---------GG-DILTAL----RENDFTIEQVRRYFIQ-------ICSALEYCQK-LHISHRD-IKAENLLLRKGRQSVVITDF
 .|..  .|.||||..         || . .. |    .|  |. |..| |. .       |..||||  . ..| ||| .| ||.|| .    . .|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED-GHIKLTDF

GLSALTEDAEDDDGQGG----------------------------------GEQKAPGTRGS--KLLTTACG--SPHYVSPEVVSKTNVGYFGEKADIWS
||.    . .....| .                                    .  . || .  .. .| ||  .|.|..||..        |  .|.||
GLCKEGMNDGEKGQQ-SQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQ-E-DDTTR-KKRDRTWTFCGPCTPEYMAPEIL-------YGKACDWWS

--VGVLLYLMLGRTLPFQANTLE----------ALFERIRTGQFSFPEDRVKK----------GYFTKESMGLIISMLNIDPAKRPS----------FTQ
  .|.|.| ||    ||.... .           .|..|. |.. ....               .|..| . ||  .|. ||.||.           . .
FGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEE

ILESDYV
| .  . 
IKNHPWF
Kinase GL50803_16235.AA AMPK 74-353 34 1.2e-82 245.14 In-house 1-254 (254) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-254/254
Sequence Identity: 34% (98 aa)

YEVTGVLGRGTYATVKLATDSRTKEEVAIKIITKSGQLTKKQLKHIRTEIVVLRLVSHPNIVKLKEIL-ASKNKIYIVMEYLEGGDILT-ALRENDFTIE
| .   .|.||.  ||..|  .|.|.|||||. |     ..  . |. ||  |.|. ||.|..| |..  ..  |..||||  ||.      . .  ...
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

QVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQSVVITDFGLSALTEDAEDDDGQGGGEQKAPGTRGSKLLTTACGSPHYVSPEVVSKTNVGYFG
. .|.| || |..||| .. |.||| | |||||    ... | ||||| . .|.|                   .| |||||| | .||..|  .  | |
EACRFFQQIISGVEYCHRHMIVHRDLKPENLLLD-HNKNIKIVDFGLSNMMKDGE-------------------FLKTACGSPCYAAPEMIS--GKLYCG

EKADIWSVGVLLYLMLGRTLPFQANTLEALFERIRTGQFSFPEDRVKKGYFTKESMGLIISMLNIDPAKRPSFTQILESDYV
 . |||| || || ||...|||      .|. .|. |... |.      ....|. .|| .||. || || .. .| .... 
PEVDIWSCGVILYAMLCGYLPFDDENTPTLYKKIKNGEYYIPK------FLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase GL50803_16235.AA Pkinase 74-353 28 1.4e-79 275.53 Pfam 1-293 (293) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-293/293
Sequence Identity: 28% (90 aa)

YEVTGVLGRGTYATVKLATDSRTKEEVAIKIITKSGQLTKKQLKHIR-TEIVVLRLVSHPNIVKLKEILASKNKIYIVMEYLEGG----DILTALR---E
|.. ...|.|....|.....  | ..||.||| |...  .|.  |.| .|| ... ..|||||.|...  .|..||.||||.|||    |  . ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NDF--TIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQSV----VITDFGLSALTEDAEDDDGQGGGEQKAPGTRGSKLLTTACGSPHYVSP
. |  . .....|. ||...|||| .  | |||.| ||.|.   .  .     |.||||... .                 .  .  .|| ||.|.|..|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFD-----------------Y-NNS-MTTFCGTPWYMAP

EVVSKTNVGYFGEKADIWSVGVLLYLMLGRTLPFQAN------TLEALFERIRTGQFSFPED----------------RVKKGYFTKESMGLIISMLNID
||.      | | |.|.||.|..|| || . .||.        .  ....||. ....|...                ...  . ..|   .| ..|. |
EVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKD

PAKRPSFTQILESDYV
|.|||...|||.....
PKKRPTAEQILQHPWF
Kinase GL50803_16235.AA MARK 74-353 32 8.3e-77 250.61 In-house 1-262 (262) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-262/262
Sequence Identity: 32% (94 aa)

YEVTGVLGRGTYATVKLATDSRTKEEVAIKIITKSGQLTK-KQLKHIRTEIVVLRLVSHPNIVKLKEILA--SKNK-IYIVMEYLEGGDILTALREN---
|..  ..| |.||.||||.. .|...|||||. |  .|.. ...| .. || ......||||.|| ..     ... ||..||| .||. .  ...    
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKF-KLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNG

DFTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGR-QSVVITDFGLSALTEDAEDDDGQGGGEQKAPGTRGSKLLTTACGSPHYVSPEVVSKT
  . |  ||.| ||.||..|| . .| |||||.||.|. . . . . |.|||.|.  .  .                    |.| ||.| | .||...| 
RLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-------------------LNTFCGTPPYMAPEIFLK-

NVGYFGEKADIWSVGVLLYLMLGRTLPFQANT--LEALFERIRTGQFSFPEDRVKKGYFTKESMGLIISMLNIDPAKRPSFTQILESDYV
   | | |.|||| ||.|| |.  ..|| . |  .. |...|..|....|          ||   || ..|...| .||. ..|..   .
-KPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH------VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase GL50803_16235.AA Ciliate-E2 74-353 23 3.2e-74 252.9 In-house 1-365 (365) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-365/365
Sequence Identity: 23% (90 aa)

YEVTGVLGRGTYATVKLATDSRTKE-----------------------EVAIKIITKSGQLTKKQLKHIR----------TEIVVLRLVSHPNIVKLKEI
|..  ..|.|....|..... ....                       ..|.||. |..   .|| .||            |  .|....||||.|..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LA--SKNKIYIVMEYLEGGDILTALREN------------DFTIEQVRRYFIQICS---------------ALEYCQKLH-ISHRDIKAENLLLRKGRQS
    ..|.||.||||..||| .  ...|             ||........ ||..               ||||. . . | ||||| ||.|.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

VVITDFGLSA-LTEDAEDDDGQGGGEQKAPGTRGSKLLTTA--------------CGSPHYVSPEVVSKTNVG------YFGEKADIWSVGVLLYLMLGR
. |.|||||  ...| ..  . . . .. .  .. .  |.               ||.|.|..||.... . .      . ..|.||||.||.|| ||  
IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

TLPFQANTLEALFERIRTGQFSFPEDRV------------KKGYFTKESMGLIIS----MLNIDPAKRPS-FTQILESDYV
 .||        .. |  ....||.               .. . ..| . ||      ||. || ||.. . |||.  . 
KPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_16235.AA QIK 74-353 33 1.5e-65 224.06 In-house 1-272 (272) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-272/272
Sequence Identity: 33% (100 aa)

YEVTGVLGRGTYATVKLATDSRTKEEVAIKIITKSGQLTKKQLKHIRTEIVVLRLVSHPNIVKLKEILASKNKIYIVMEYLEGGDILTALRENDF-----
|..   .|.| .|.||||.   ||..|||||| || ||... |. .  |. .. . .||.|.|| ... ... .|||.|| ..|..  .| ..       
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKS-QLDEENLQKCYREVQIMKMLYHPHIIKLYQVMETDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

----------------TIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQSVVITDFGLSALTEDAEDDDGQGGGEQKAPGTRGSKLLTTACG
                . .. || | ||||| .|| |..| |||.||||.|| .    . | |||.| . .  .                   || | ||
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMN-IKIADFGFSNWFKQGQ-------------------LLMTWCG

SPHYVSPEVVSKTNVGYFGEKADIWSVGVLLYLMLGRTLPFQANTLEALFERIRTGQFSFPEDRVKKGYFTKESMGLIISMLNIDPAKRPSFTQILESDY
|| |  ||.    .  | | |.|||| ||.|| .    |||   ||. | .|.  |.|  |       .  ..   ||  || .||..| .  ||..   
SPPYAAPEMFEGKE--YDGPKVDIWSMGVVLYVLVCGALPFDGKTLQNLRQRVLSGKFRIPF------FMSQDCEHLIRHMLVVDPEHRYTIMQICQHRW

V
 
M
Kinase GL50803_16235.AA RSK 74-353 26 1.8e-61 210.51 In-house 1-278 (278) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-278/278
Sequence Identity: 26% (81 aa)

YEVTGVLGRGTYATVKLATDSRTKEEVAIKIITKSGQLTKKQ-LKHIRTEIVVLRLVS-HPNIVKLKEILASKNKIYIVMEYLEGGDILTALR-END---
 .| | .| | . ...  |.. |. . | |.. |.   ...  ..| .||. .| ..  ||.||.|..    . |.|..|||..||. .| |. |     
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRK--GRQSVVITDFGLSALTEDAEDDDGQGGGEQKAPGTRGS--KLLTTACGSPHYVSPEVVS
|. . .. |. .| .|.|.  ...| |||.| || |.    .. ....||||.. ..                   | .  ... | |.. .|. ||.. 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------RCDHNQWTMTFCYTIEYMAPEMLK

KTN-VGYFGEKADIWSVGVLLYLMLGRTLPFQA---NTLEALFERIRTGQ--FSFPEDRVKKGYFTKESMGLIISMLNIDPAKRPS-----FTQILESDY
. |  |  .. .|.|| |||.| ||   .|||.   |. . ...||..|.  ...|..     | ..|   ||  ||  ||.||..       .|... .
RANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQ----YLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPW

V
 
F
Kinase GL50803_16235.AA ULK 74-219 27 1.2e-40 141.4 In-house 1-185 (324) Show / Hide 
Range on Protein: 74-219
Range on HMM: 1-185/324
Sequence Identity: 27% (51 aa)

YEVTGVLGRGTYA-TVKLATDSRT---KEEVAIKIITKSGQLTKKQL-------KHIRTEIVVLRLVS---HPN--IVKLKEILASK--NKIYIVMEYLE
|..  .|| |... .|  ... .|   .. ||.|.| |...  ||..       . .. || ...      |||  ||||.... ..  | |||.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDILTALREN----------DFTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQS-----------VVITDFGLS
|||  . . .|           .. .... .|.|||... . .|  | ||||| .|.|. .| ..           . |.|||..
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase GL50803_16235.AA ULK 74-219 26 3.8e-40 137.86 In-house 1-189 (329) Show / Hide 
Range on Protein: 74-219
Range on HMM: 1-189/329
Sequence Identity: 26% (51 aa)

YEVTGVLGRGTYATVKLATDSRTK----EEVAIKIITKSGQLTKKQLKH-------IRTEIVVLRLVS--------HPNIVKLKEILASK--NKIYIVME
|..  .|| |....|  ... .||    | ||.|.| |. .  |...         .. || ...           |||||||.... ..  | |||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YLEGGDILTALREN-----------DFTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQS-----------VVITDFGLS
| .|||  . . .|            .. .... .|.||.... . .|  | ||||| .| |. .| ..           . |.|||..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase GL50803_16235.AA CAMK1 74-160 33 9.7e-36 101.32 In-house 1-96 (276) Show / Hide 
Range on Protein: 74-160
Range on HMM: 1-96/276
Sequence Identity: 33% (34 aa)

YEVTGVLGRGTYATVKLATDSRT---KEEVAIKIITKSGQLTKKQLKH--------IRTEIVVLRLV---SHPNIVKLKEILASKNKIYIVMEYLEGGDI
||.. ..|||. ..|.|.|. .|   ....|||.| |     ||..|.        ...|| ... |   .||||.|..|.  |.|..|.|||.. ||..
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK-----KKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGEL

L
.
F
Kinase GL50803_16235.AA CAMK1 179-353 32 1.7e-35 100.57 In-house 116-276 (276) Show / Hide 
Range on Protein: 179-353
Range on HMM: 116-276/276
Sequence Identity: 32% (61 aa)

QICSALEYCQKLHISHRDIKAENLLLR-KGRQS-VV--ITDFGLSALTEDAEDDDGQGGGEQKAPGTRGSKLLTTACGSPHYVSPEVVS-KTNVGYFGEK
||.||.||. .. | |||.| ||||.. |  .| ..  | |||||  ... |.                  |..||||.| || |||.  |      . .
QILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN------------------LMKTACGTPGYVAPEVLECKK-DKPYDKA

ADIWSVGVLLYLMLGRTLPFQANT-LEALFERIRTGQFSFPEDRVKKGYFTKESMG----LIISMLNIDPAKRPSFTQILESDYV
 |.||.|| .| .|    ||....  . ||| |  ... ||..     .. . | .    .|  ||. || ||....|.|.   .
CDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSP-----WWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase GL50803_16235.AA ULK 246-353 23 2.5e-19 65.29 In-house 197-324 (324) Show / Hide 
Range on Protein: 246-353
Range on HMM: 197-324/324
Sequence Identity: 23% (30 aa)

LLTTAC------GSPHYVSPEVVSKT--NVGYFGEKADIWSVGVLLYLMLGRTLPFQANTLEALFER--------------IRTGQFSFPEDRVKKGYFT
...|..      |.| | .|.....   .  |   |.||||.|...| ||    ||...  . ....              |.. .. ||  . |   . 
MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKIS

KESMGLIISMLNIDPAKRPSFTQILESDYV
.|.  ||  || .|. .| |...|..   .
PECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_16235.AA ULK 246-353 22 3.9e-19 63.53 In-house 201-329 (329) Show / Hide 
Range on Protein: 246-353
Range on HMM: 201-329/329
Sequence Identity: 22% (30 aa)

LLTTAC------GSPHYVSPEVVSKT--NVGYFGEKADIWSVGVLLYLMLGRTLPFQANTLEALF-----ER----------IRTGQFSFPEDRVKKGYF
...|.       |.| | .|.....   .  |   |.||||.|...| ||    ||.|.  . ..     .           |.. .. || |  ..  .
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDG-NDPQI

TKESMGLIISMLNIDPAKRPSFTQILESDYV
 .|.  ||  || .|. .| |......   .
SPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_16235.AA Pkinase_Tyr 74-219 29 2.3e-18 62.84 Pfam 1-158 (270) Show / Hide 
Range on Protein: 74-219
Range on HMM: 1-158/270
Sequence Identity: 29% (48 aa)

YEVTGVLGRGTYATVKLATDS----RTKEEVAIKIITKSGQLTKKQ--LKHIRTEIVVLRLV-SHPNIVKLKEILA-SKNK--IYIVMEYLEGGDILTAL
 .   .||.| . .|...|       || .||.|.. |  . ...|  ..    |. ...   .|||||.|  .    .    ||||||| ..|| |. |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

REN-----DFTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQSVVITDFGLS
|..      .|...   . .||....||    .. |||. | | |. ...  | |.||||.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENN-VVKICDFGLA
Kinase GL50803_16235.AA TyrKc 74-353 21 6.7e-17 50.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 74-353
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

YEVTGVLGRGTYATVKLATDSRTKEEVAIKIITKSGQLTKKQLKHIRTEIVVLRLV--SHPNIVKLKEILASK-------NKIYIVMEYLEGGDILTALR
 .   .||.| . .| ..| .   ..||.| . ..       .. .. |. ... .  .|||||.|  .  ..         ..||||| ..|| .  ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

END--FTIEQVRRYFIQICSALEYCQKLHISHRDIKAENLLLRKGRQSVVITDFGLSALTEDA-------EDDDGQG--GGEQKAPGTRGSKLLTTACGS
..   .. ..   . .||..  ||  . .. |||. | | |. ...  | |.|||||   .|        .  . ..  ||    |              
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP--------------

PHYVSPEVVSKTNVGYFGEKADIWSVGVLLY--LMLGRTLPFQA----NTLEALFERIRTGQFSFPEDRVKKGY------FTKESMGLIISMLNIDPAKR
    .||.    | | | .| |.|| ||...  . .| . .        . . ..|....|    . . .   |       ..|   .. .  . ||..|
IRWMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPND---YPMSFVCCPDEMYQIMKQCWHEDPEDR

PSFTQILESDYV
|.|..|   .. 
PTFSEI--HECF
Kinase GL50803_16235.AA Pkinase_Tyr 335-349 46 1.298103 2.7 Pfam 254-268 (270) Show / Hide 
Range on Protein: 335-349
Range on HMM: 254-268/270
Sequence Identity: 46% (7 aa)

NIDPAKRPSFTQILE
. ||..||.|..|.|
HYDPEDRPTFSEIHE