GL50803_17250

Species: G.lamblia
Alias: GL50803_17250, GK141
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_17250.AA Protein None 854 None Fasta, JSON
GL50803_17250.kin_dom Protein Kinase Domain None 272 None Fasta, JSON

Protein domain

Protein domains of GL50803_17250.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_17250.AA S_TKc 9-282 13 3.2e-07 -71.09 SMART 1-231 (231) Show / Hide
Range on Protein: 9-282
Range on HMM: 1-231/231
Sequence Identity: 13% (43 aa)

YEAVRYLNSDIYGISYLVRDRNLDLSATCRIVSEADVGRGRYALIRDLARQAHRLDHESITPLLEAFVDDEQECIFLISRGAG--QSLYEYSEELCF--L
|| .| . .  .|  |..|... .    . |..          ..| ..   .  .|. |  |...|.|  ..  .      |   .|..| ..     |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

QVNLEEEVIITILVELINAILYVYSTNRK------------------TDFTDALASNLPSTGLDPLCIRLSSKGRALVDYSAFAVKLAAQRHSAFTMAYL
.. . | ..  .. ....|. |  |  .                   .||  |                                     ..   |  |.
RFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDEHIKICDFGLARQL----------------------------------TTFCGTPWYM

CPEVLHSRHSGEDRARLNVSPLKMLAYNV--------GRLCCELCFAGSKCKAVKGEYDTAYMLKSIIKENAYSKDLVRVLTWLTNPCNNSRPYLDEVLA
 ||||                     |.         | .  |..             . . |.| |      |...   .  . .   . ||   |.|.
APEVL--------------------GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG-----SPEAKDFIRKCLQKDPEKRPTA-EALQ

-------HPFI
       ||..
DEWDIKCHPWF

Kinase GL50803_17250.AA NEK 246-282 28 0.000119 12.75 In-house 249-286 (286) Show / Hide
Range on Protein: 246-282
Range on HMM: 249-286/286
Sequence Identity: 28% (11 aa)

IKENA-YSKDLVRVLTWLTNPCNNSRPYLDEVLAHPFI
| ..  ||.|| .... . ..   .||  ...|..|||
IPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI

Kinase GL50803_17250.AA MLCK 268-282 33 0.000244 6.78 In-house 243-257 (257) Show / Hide
Range on Protein: 268-282
Range on HMM: 243-257/257
Sequence Identity: 33% (5 aa)

NSRPYLDEVLAHPFI
..|.. .| |.||..
EKRMTAHECLQHPWL

Kinase GL50803_17250.AA Aur 268-282 40 0.000497 5.97 In-house 243-257 (257) Show / Hide
Range on Protein: 268-282
Range on HMM: 243-257/257
Sequence Identity: 40% (6 aa)

NSRPYLDEVLAHPFI
..|  ||....||.|
KQRMTLDQIMNHPWI

Ank GL50803_17250.AA Ank 333-354 45 0.001357 17.22 Pfam 1-22 (33) Show / Hide
Range on Protein: 333-354
Range on HMM: 1-22/33
Sequence Identity: 45% (10 aa)

DGATALMAAAVLGNIEVLKILI
|| |.|. |.  |..||.| |.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_17250.AA Ank 369-389 52 0.003317 15.82 Pfam 1-21 (33) Show / Hide
Range on Protein: 369-389
Range on HMM: 1-21/33
Sequence Identity: 52% (11 aa)

NGATALILAARNGQTEACKLL
.| |.| ||.|.|.|| .|.|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_17250.AA Ank 400-433 35 0.006362 14.8 Pfam 1-33 (33) Show / Hide
Range on Protein: 400-433
Range on HMM: 1-33/33
Sequence Identity: 35% (12 aa)

DGFTALMEATVRGHSSAADVLMKYEAKSVIQLDD
||||.|. |  .|| . .  |..    .|   ||
DGFTPLHLACRCGHTEVVKMLLQ-HGADVNAQDD

Ank GL50803_17250.AA Ank 439-464 34 0.010335 14.04 Pfam 1-26 (33) Show / Hide
Range on Protein: 439-464
Range on HMM: 1-26/33
Sequence Identity: 34% (9 aa)

NGTTALMLACEFHQLHIANSLIQYEA
.| |.|.|||.  .. ..  |.|. |
DGFTPLHLACRCGHTEVVKMLLQHGA

Ank GL50803_17250.AA Ank 470-491 40 0.006201 14.84 Pfam 1-22 (33) Show / Hide
Range on Protein: 470-491
Range on HMM: 1-22/33
Sequence Identity: 40% (9 aa)

SGYTALHRAAALGLVSAVKLLI
 |.|.|| |.  | .. ||.|.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_17250.AA Ank 502-522 38 0.000256 19.83 Pfam 1-21 (33) Show / Hide
Range on Protein: 502-522
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

KGQTALMFAAQYGHSKCVELL
 |.|.|. |...|| ..|..|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_17250.AA Ank 534-557 37 0.001719 16.85 Pfam 1-24 (33) Show / Hide
Range on Protein: 534-557
Range on HMM: 1-24/33
Sequence Identity: 37% (9 aa)

KGWSALMSAITNGHTEAAKLLIDY
 |...|. |. .|||| .|.|...
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_17250.AA Ank 565-585 38 0.00069 18.28 Pfam 1-21 (33) Show / Hide
Range on Protein: 565-585
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

MGYTPLMCAVEHKQYEVIDLL
.|.|||..|... ..||. .|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_17250.AA Ank 605-627 26 0.022092 12.85 Pfam 1-23 (33) Show / Hide
Range on Protein: 605-627
Range on HMM: 1-23/33
Sequence Identity: 26% (6 aa)

NGATALMLAAYSNDADGCRKLVE
.| |.|.||....... .. |..
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_17250.AA Ank 636-656 23 2.261281 5.6 Pfam 1-21 (33) Show / Hide
Range on Protein: 636-656
Range on HMM: 1-21/33
Sequence Identity: 23% (5 aa)

DGMTASMIAASNDSAAALSIL
||.|. ..|......  .. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_17250.AA Ank 673-705 24 0.004148 15.47 Pfam 1-33 (33) Show / Hide
Range on Protein: 673-705
Range on HMM: 1-33/33
Sequence Identity: 24% (8 aa)

DNRTCLMIAALSRSLSCVRVLAEQRIGMGCQDG
| .|.|..|... ....|. | ..      || 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_17250.AA Ank 706-726 33 0.021535 12.89 Pfam 1-21 (33) Show / Hide
Range on Protein: 706-726
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

KGSTALIMAALSGYADICKVL
 | |.| .|...|.....| |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_17250.AA Ank 737-765 48 2e-06 27.46 Pfam 1-29 (33) Show / Hide
Range on Protein: 737-765
Range on HMM: 1-29/33
Sequence Identity: 48% (14 aa)

DGFTALMSAAQEGHKECVSILLSKEGDVH
||||.|. |.. ||.|.|. ||..  ||.
DGFTPLHLACRCGHTEVVKMLLQHGADVN

Ank GL50803_17250.AA Ank 768-788 33 0.006568 14.75 Pfam 1-21 (33) Show / Hide
Range on Protein: 768-788
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

GGWTALMSAALKNKPEIVQIL
 |.|.|. |.... .|.|. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_17250.AA Ank 802-822 42 3.5e-05 22.93 Pfam 1-21 (33) Show / Hide
Range on Protein: 802-822
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

DGITALMIAVQSGHIECIRIL
|| |.|..|...||.|... |
DGFTPLHLACRCGHTEVVKML