Gene GL50803_21435 (G.lamblia)
GL50803_21435
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_21435.AA | Protein | None | 597 | None | Fasta, JSON |
| GL50803_21435.kin_dom | Protein Kinase Domain | None | 320 | None | Fasta, JSON |
Protein domains of GL50803_21435.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | GL50803_21435.AA | CAMK1 | 87-125 | 30 | 6.3e-11 | 27.93 | In-house | 1-43 (276) | Show / Hide |
Range on Protein: 87-125 Range on HMM: 1-43/276 Sequence Identity: 30% (13 aa) YTFHEAIGTGRTGTVYRCTSIRS---RDTVAIKVIK-AREIQG | |.. ||.| ..||.|| ... . .|||.|. . ... YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKK |
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| Kinase | GL50803_21435.AA | MLCK | 87-122 | 41 | 3.2e-10 | 22.59 | In-house | 1-36 (257) | Show / Hide |
Range on Protein: 87-122 Range on HMM: 1-36/257 Sequence Identity: 41% (15 aa) YTFHEAIGTGRTGTVYRCTSIRSRDTVAIKVIKARE | .|| .| |. |.|.||. . .|.| |.||.|. YQIHEELGRGKFGIVHRCIEKSTGKTWAAKFIKCRK |
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| Kinase | GL50803_21435.AA | PAKA | 87-119 | 42 | 2.7e-09 | 28.9 | In-house | 1-35 (260) | Show / Hide |
Range on Protein: 87-119 Range on HMM: 1-35/260 Sequence Identity: 42% (15 aa) YTFHEAIGTGRTGTVYRCTSIRSRDT--VAIKVIK |.| | || | .|.||..|.|. .. ||||... YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMN |
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| Kinase | GL50803_21435.AA | S_TKc | 87-403 | 12 | 2.8e-09 | -40.76 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 87-403
Range on HMM: 1-231/231
Sequence Identity: 12% (46 aa)
YTFHEAIGTGRTGTVYRCTSIRSRDTVAIKVIKAREIQGFNEYRLCQWVETLIGLDVAGIAKFYKVYADKSRRIFYVIMKYYSN--GSIANSISGGNR-C
|.... || | |.||.|. ... ||||.|| .... .. | . | |.| |. | .|..| | .. |. | .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG
KWAGANNERVYDACTRLISAISFLHNRLWVI--------------------NTATIGVPLGAISLDNILLDDELSLCFLPGIGAPLNWVGSTFPAEAPNN
. . . .. . ...|. ..|.. ..| |..
LRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDEHIKICDFGLARQL-------------------------------------------
QLSAPAPEKIVTPGRQKTRPNPGAKANILGDSSLIPGRIELPVKGYVPTKD------CWMLPWNNISYLRPTF-ASDSWDLGCLLFALIFQKYPFRKPKA
. .. | . . .. ..| | .||.|. .. . ||.
-------------------------------------------TTFCGTPWYMAPEVL-----------GYGKCKCDWWSCGCILYEMLCGYPPFP----
TQQSYVLSEKVMETIGTTLKPIGEIICGLLVPDPSDRMSTLQAYN---------ML
| ... .|.. . . .|...|. ||..|.. .| . .
--QMQMMFKKIG-----SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | GL50803_21435.AA | CAMK | 92-165 | 15 | 3.5e-09 | 24.98 | In-house | 1-136 (425) | Show / Hide |
Range on Protein: 92-165 Range on HMM: 1-136/425 Sequence Identity: 15% (21 aa) AIGTGRTGTVYRCTSIRSR------------DTVAIKVIKAREIQ--------------------------GFNEYRLCQWVETLIG-------LDVAGI .|.|. |.|..|. ... ||||.|. . .. .... .. . .| . || | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI AKFYKVYADKS-----------------RRIFYVIM |.| || |.. .. .| .| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVM |
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| Pkinase | GL50803_21435.AA | Pkinase | 87-123 | 37 | 5.6e-09 | 32.82 | Pfam | 1-37 (293) | Show / Hide |
Range on Protein: 87-123 Range on HMM: 1-37/293 Sequence Identity: 37% (14 aa) YTFHEAIGTGRTGTVYRCTSIRSRDTVAIKVIKAREI |.... || | |.||.|. . ....||.|.|| |.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHE |
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| Kinase | GL50803_21435.AA | STE20 | 87-119 | 32 | 1.5e-07 | 24.02 | In-house | 1-37 (288) | Show / Hide |
Range on Protein: 87-119 Range on HMM: 1-37/288 Sequence Identity: 32% (12 aa) YTFHEAIGTGRTGTVYRCTSIRSRDT----VAIKVIK |.. | || | .|.||... ... . ||||... YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMN |
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| Kinase | GL50803_21435.AA | MARK | 87-119 | 27 | 9.3e-07 | 18.31 | In-house | 1-33 (262) | Show / Hide |
Range on Protein: 87-119 Range on HMM: 1-33/262 Sequence Identity: 27% (9 aa) YTFHEAIGTGRTGTVYRCTSIRSRDTVAIKVIK | . ||.| ..|. ....... ||||... YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYE |
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| Kinase | GL50803_21435.AA | CAMKL | 87-124 | 35 | 9.9e-07 | 17.35 | In-house | 1-39 (297) | Show / Hide |
Range on Protein: 87-124 Range on HMM: 1-39/297 Sequence Identity: 35% (14 aa) YTFHEAIGTGRTGTVYRCTSIRS-RDTVAIKVIKAREIQ |.. . .|.| |.| .| || . ||||.|. . |. YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIW |
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| Kinase | GL50803_21435.AA | NuaK | 87-124 | 36 | 3e-06 | 11.88 | In-house | 1-38 (252) | Show / Hide |
Range on Protein: 87-124 Range on HMM: 1-38/252 Sequence Identity: 36% (14 aa) YTFHEAIGTGRTGTVYRCTSIRSRDTVAIKVIKAREIQ | | . | | | | . | . . |||| || |. YEFQKTLGKGTYGKVKLATEHSTGREVAIKSIKKCKIE |
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| Kinase | GL50803_21435.AA | Ciliate-E2-Unclassified | 330-401 | 19 | 5.4e-05 | 13.3 | In-house | 249-348 (352) | Show / Hide |
Range on Protein: 330-401 Range on HMM: 249-348/352 Sequence Identity: 19% (19 aa) FASDSWDLGCLLFALIFQKYPFRKPKATQ---------------QSYVLS-EKVMETIG-------TTLKPIG-----EIICGLLVPDPSDRMSTLQAYN ...| | ||..|....|..||| .. .| | | .| . .. | . .... .|. .|. |.. |. | YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILN |
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| Kinase | GL50803_21435.AA | Ciliate-E2 | 87-172 | 20 | 0.000195 | 11.12 | In-house | 1-120 (365) | Show / Hide |
Range on Protein: 87-172 Range on HMM: 1-120/365 Sequence Identity: 20% (24 aa) YTFHEAIGTGRTGTVYRCTSIRSRD-----------------------TVAIKVIKAREIQGF-NEYRLCQWVE----------TLIGLDVAGIAKFYKV | |.. ||.| |.||.|. .. . .|.|..| ..|. . .| .... .. | |. | |.| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YADKSRRIFYVIMKYYSNGS . .|.. .| .| |.. |. FQEKDDNNIYLVMEYCQGGD |
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| Kinase | GL50803_21435.AA | Ciliate-E2 | 329-401 | 13 | 0.000308 | 10.43 | In-house | 274-361 (365) | Show / Hide |
Range on Protein: 329-401 Range on HMM: 274-361/365 Sequence Identity: 13% (16 aa) TFASDSWDLGCLLFALIFQKYPFRKPKATQQSYVLSEKVMETIGTTLKPIGEIICG-----------------------------------------LLV ....| | ||..|. ..| |.|| ..|. .|. DYKCDIWSLGVILYEMLFGKPPF---------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQ PDPSDRMS-TLQAYN ||. |.. |. | KDPEKRITGWEQILN |
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| Kinase | GL50803_21435.AA | NuaK | 333-351 | 42 | 0.000548 | 5.78 | In-house | 181-199 (252) | Show / Hide |
Range on Protein: 333-351 Range on HMM: 181-199/252 Sequence Identity: 42% (8 aa) DSWDLGCLLFALIFQKYPF |.| || ||..... || DCWSLGVLLYTMVYGTMPF |
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| Kinase | GL50803_21435.AA | Pkinase | 329-403 | 13 | 0.00093 | 14.37 | Pfam | 190-293 (293) | Show / Hide |
Range on Protein: 329-403 Range on HMM: 190-293/293 Sequence Identity: 13% (14 aa) TFASDSWDLGCLLFALIFQKYPFRKP----KATQQSYVLSEKVMETIGTTL------------------------KPIGEIICGLLVPDPSDRMSTLQAY . ..| | .||.|. ... . ||. . | ... .. . . .. ..|...| .||..| . |. GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL NM--L . . QHPWF |
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| Kinase | GL50803_21435.AA | CAMK | 329-401 | 18 | 0.001647 | 6.38 | In-house | 312-421 (425) | Show / Hide |
Range on Protein: 329-401 Range on HMM: 312-421/425 Sequence Identity: 18% (20 aa) TFASDSWDLGCLLFALIFQKYPFRKPKATQQS---------YVLSEKVM----ETIGTTLKP------------------------IGEIICGLLVPDPS ....| | .|..|... ..||. .. .. | | ||.| . . ..| |...|..||. GPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPE DRMSTLQAYN .||. |. | KRMTIEQCLN |
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| Kinase | GL50803_21435.AA | Ciliate-E2-Unclassified | 87-104 | 44 | 0.004806 | 6.43 | In-house | 1-18 (352) | Show / Hide |
Range on Protein: 87-104 Range on HMM: 1-18/352 Sequence Identity: 44% (8 aa) YTFHEAIGTGRTGTVYRC |.... ||.| |.||.| YKIIKQIGQGGFGKVYKC |
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| Kinase | GL50803_21435.AA | MLCK | 382-399 | 38 | 0.023837 | 1.43 | In-house | 234-251 (257) | Show / Hide |
Range on Protein: 382-399 Range on HMM: 234-251/257 Sequence Identity: 38% (7 aa) ICGLLVPDPSDRMSTLQA |. ||| |...||.. .. ISRLLVKDKEKRMTAHEC |
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| Kinase | GL50803_21435.AA | CAMKL | 330-395 | 18 | 0.044688 | 2.25 | In-house | 215-287 (297) | Show / Hide |
Range on Protein: 330-395 Range on HMM: 215-287/297 Sequence Identity: 18% (14 aa) FASDSWDLGCLLFALIFQKYPFRKPK----ATQQSYVLSEKVMETIGTTL----K-PIGEIICGLLVPDPSDRMS .. | | .| .|.|... ..||. . | .|.|.. . . .| ..|...|..|.. PKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPT |
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| Zf-C3HC4 | GL50803_21435.AA | zf-C3HC4 | 549-585 | 27 | 1.3e-07 | 23.08 | Pfam | 1-48 (48) | Show / Hide |
Range on Protein: 549-585 Range on HMM: 1-48/48 Sequence Identity: 27% (13 aa) CVVCLHRPKNIK---LDPCKHV----CICHECYLQLLD----KRCPIC | .|. .|. . . ||.| . ||.|... .. . |||| CWICHCEWKDPNNPLIHPCGHRGSLKWFCHSCIKRWWNHSGNTQCPIC |
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| RING | GL50803_21435.AA | RING | 549-585 | 32 | 0.000236 | 19.77 | SMART | 1-23 (23) | Show / Hide |
Range on Protein: 549-585 Range on HMM: 1-23/23 Sequence Identity: 32% (12 aa) CVVCLHRPKNIKLDPCKHVCICHECYLQLLDKRCPIC | .|| ... || | .|. | |||| CPICLE----PVVLPCGH--FCY-CI-------CPIC |
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