Gene GL50803_5375 (G.lamblia)

GL50803_5375

Species: G.lamblia
Alias: GL50803_5375, GK170
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-GL2

Sequence

Name Sequence Type Origin Length Description Download
GL50803_5375.AA Protein None 405 None Fasta, JSON
GL50803_5375.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of GL50803_5375.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_5375.AA NEK 35-301 43 8e-127 427.63 In-house 1-286 (286) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-286/286
Sequence Identity: 43% (126 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRI-----FACKEIDYAKMSEKEKKLLV-HEVNTLKELSHENIVSYIDRFVERENAKMFIVMEYCE-NGDLARY---
|  .  ||.||||||.||... .|..     .. |.|.. .||||||. .. .||. ||.| |.|||.|.|.|.|..| ...||||||| .|||..    
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IKRHKTDRRYIAEEKIWSVFVQLLHALNYCHSL--HKHDDTGTHKVIHRDIKPGNVFLTRDGS----IKLGDFGLCRSLG-ELSQAKT-NVGTPLYMAIE
||..|  . |. ||.|| .|.|.. ||.|.|.           .|..|||||| |.|||....    .|.||||. . |. . . |.|  |||| ||. |
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGP------QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPE

VLQKQSYTEKADIWSLGCVIYELCALQP--PFVAS--NMDSLKAKVKQG-ARPAIPAH--YSSDLSAVIDSMLNSNFNSRPSAAELLNHRKI
|.| ..|..|.||||||||.||.|.|.|  || |.  || ||  |...|   | || |  ||.||. .| .||. .  .|||. ..|..  |
VCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_5375.AA NEK2 35-301 41 3.5e-122 412.2 In-house 1-319 (319) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-319/319
Sequence Identity: 41% (131 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRIFACKEIDYAKMSEKEKKLLVHEVNTLKELSHENIVSYIDRFVERENAKMFIVMEYCENGDLARYIKRHKTDRRY
|  |  ||.||||.. ||     |.|.. |||.| .| |||. .|| |.| |..| |.||| | |. . |.|    ||||||| |||.  ||. . .|.|
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

IAEEKIWSVFVQLLHALNYCHS------------LHKHDDTGTHKVIHRDIKPGNVFLTRDGS-------------------------------------
. || || .. ||. ||  ||               |    | | ..||||||.|.||  |..                                     
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--IKLGDFGLCRSLG-ELSQAKTNVGTPLYMAIEVLQKQSYTEKADIWSLGCVIYELCALQPPFVASNMDSLKAKVKQGARPAIPAHYSSDLSAVIDSML
  .||||||| |.|  . | |.| |||| ||  |... |.| || ||||.||.|||.||| ||| | | . |  |.|||    ||. ||..|...| .|.
VVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHFMI

NSNFNSRPSAAELLNHRKI
| .  .|||  |.| |  |
NVDHYHRPSIEEILQHPQI
Kinase GL50803_5375.AA NEK1 35-301 39 2.2e-91 309.9 In-house 1-276 (276) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-276/276
Sequence Identity: 39% (112 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRIFACKEIDYAKMSEKEKKLLVHEVNTLKELSHENIVSYIDRFVERENAKMFIVMEYCENGDLARYIKRHKTDRRY
|. . .||.|||||. .|...  |. .. |||   ||.|||.   . ||. |. . |.|||.| . |.|. .   .||||||..|||.. |.| |     
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

IAEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDIKPGNVFLT--RDG---------------SIKLGDFGLCRSLGE-LSQAKTNVGTPLYMAIE
. |  | . |.|.  |||. |.          |..|||||. |.|||  ..|                .||||||  | | . .. |.| .||| |   |
FSEDQIMHWFCQICLALNHIHD---------RKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPE

VLQKQSYTEKADIWSLGCVIYELCALQPPFVASNMDSLKAKVKQGARPAIPAHYSSDLSAVIDSMLNSNFNSRPSAAELLNHRKI
  |.. |. | |||||||| ||||.|  || | |.  |  |. ||  | ||.||| .|.  . .|.. |  .|||.  .|    |
ICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase GL50803_5375.AA S_TKc 35-301 33 2.2e-85 290.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-231/231
Sequence Identity: 33% (94 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRIFACKEIDYAKMSEKEKKLLVHEVNTLKELSHENIVSYIDRFVERENAKMFIVMEYCEN--GDLARYIKRHKTDR
| .|..||.|.||||.|.. .  |||.|.|.|.         . .  |.. ||.  |.||| ..| |..    ....|||||..  ||| .|||.... .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--RYIAEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDIKPGNVFLTRDGSIKLGDFGLCRSLGELSQAKTNVGTPLYMAIEVLQKQSYTE-KADI
  ... |  ..... |.. ||.||||         |..||||.|| |..|..   ||..||||.| |      .| .||| ||| |||   .|.  |.|.
LRFPFPE-HARFYMYQICCALEYCHS---------HGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDW

WSLGCVIYELCALQPPFVASNMDSLKAKVKQGARPAIPAHYSSDLSAVIDSMLNSNFNSRPSAAELLN-------HRKI
||.||..||... .|||   .|. .  |..           |...   |. .|. . . ||.| |.|.       |  .
WSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_5375.AA Pkinase 35-301 28 2.5e-81 281.27 Pfam 1-293 (293) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRIFACKEIDYAKMSEKEKKLLVH--EVNTLKELSHENIVSYIDRFVERENAKMFIVMEYCENG----DLARYIKRH
| .. .|||||||.| | . . .|.|.|.|.|.. . ...... ...  |.  .|.|.|.||| ..| | .  . .. .||||||.|    ||..||.. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST-

KTDRRYI--AEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDIKPGNVFLTRDGSI----KLGDFGLCRS--LGELSQAKTNVGTPLYMAIEVLQ-
  ... .   |. . ... |.| .|.||||          ..||||.|| |... ..| |    |..||||..   .   | ..| .||| ||| ||.. 
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

KQSYTEKADIWSLGCVIYELCALQPPFVAS----NMDSLKAKVKQGARPAIPAHYS-----------------------SDLSAVIDSMLNSNFNSRPSA
 | |. |.|.||.||..||..  .|||  .    | .. ......  .| .. ...                       ...  .|...|. . ..||.|
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

AELLNHRKI
...|.|  .
EQILQHPWF
Kinase GL50803_5375.AA STE 35-301 24 9.5e-75 254.64 In-house 1-359 (359) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-359/359
Sequence Identity: 24% (90 aa)

YIFLNIIGSGSFGKVHKVQSRT---------------NGRIFACKEIDYAKMS---------------EKEKKLLVHEVNTLKELS--HENIVSYIDRFV
. .. .||.|.||.|.|   .                .|.|.| |.... . .               ..|.. . .|....|...  |.||| |.. ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----ERENAKMFIVMEYCENGDLARYIK-RHKTDR---------RYIAEEKIWSVFVQLLHA-LNYCHSLHKHDDTGTHKVIHRDIKPGNVFLTRDGSI
     . .. . .|.|||...| |   || .... .          .. |. |  . .|.|.. |.| ||.|         .|||||||.|..|     .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---------IIHRDIKPANILL-----V

KLGDFGLCRSLGE-----------------LSQAKTNVGTPLYMAIEVLQK------QSYTEKADIWSLGCVIYELCALQPPFVA-SNMDSLKAKVKQ--
|| |||.| .| .                  .. .| |||| .|| ||.|.      . |..|.|||||||.| |..  .||.   ..|  . .. .   
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

------------GARPAIP-------------------AHYSSDLSAVIDSMLNSNFNSRPSAAELLN--HRKI
            |  | .|                    ..|...   |.  |. . | ||.| .||.  |  |
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_5375.AA CAMK 40-301 20 6.1e-69 221.04 In-house 1-425 (425) Show / Hide 
Range on Protein: 40-301
Range on HMM: 1-425/425
Sequence Identity: 20% (90 aa)

IIGSGSFGKVHKVQSR-TNGRI-----------FACKEIDYAKMS--------------------------EKEKKLLVHEVNTLKELS-------HENI
..|.||||||.... . |.|..           .|.| ||  |..                          .| .| . .|.. .| |.       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSYIDRFVERE-----------------NAKMFIVM---EYCENG----DLARYIKRH------------KTDRRYIAEEKIWSVFVQLLHALNYCHSLH
.. .. .  ..                 . .|..||   |||..|    ||  ||..|              .|... |.    .| |.. |..||||  
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHS--

KHDDTGTHKVIHRDIKPGNVFLTRD-----------------GSIKLGDFGLCRSLGELS------------------------QAKTNVGTPLYMA-IE
       |...|||.|| |. |. .                 . ||. |||. . . . .                          || .||| |||  |
-------HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

VLQKQS--------------YTEKADIWSLGCVIYELCALQPPFVAS-------------NMDSLKAKVKQGARPAIPAHYSS-----------------
||....              |..|.|.||.|.. | .    ||| ..             |.  |. |...|    .| . |                  
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF

------DLSAVIDSMLNSNFNSRPSAAELLNHRKI
      .    | .||. . . |..... |||  .
HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_5375.AA NEK4 35-301 35 7.7e-65 221.73 In-house 1-257 (257) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-257/257
Sequence Identity: 35% (96 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRIFACKEIDYAKMSEKEKKLLVHEVNTLKELSHENIVSYIDRFVERENAKMFIVMEYCENGDLARYIKRHKTDRRY
| ..  .| ||.| |  |..|  .. .  | ..  . | .|.|   ||.. |  | | |||.| . .   ..  ..||| .|| ||| |  |. | .   
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQ--F

IAEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDIKPGNVFLTRDGSIKLGDFGLCRSLG-ELSQAKTNVGTPLYMAIEVLQKQSYTEKADIWSLG
. |. .   |||   || | |           ...||| |  |.|||.   ||.||||. | |      ||| .||| ||  |.   . |  | ||||||
LEEYQVVEWFVQIAMALQYMH---------EKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLG

CVIYELCALQPPFVASNMDSLKAKVKQGARPAIPAHYSSDLSAVIDSMLNSNFNSRPSAAELLNHRKI
| .||.  |   | | .|.||  .. ||  | .|  || ||   .  ||.   . |||  ...    |
CCVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase GL50803_5375.AA ULK 35-301 29 1.2e-64 221.07 In-house 1-329 (329) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-329/329
Sequence Identity: 29% (99 aa)

YIFLNIIGSGSFGKVHKVQ-SRTN---GRIFACKEIDYAKMSEKEKK--------LLVHEVNTLKELS--------HENIVSYIDRFVERENA-KMFIVM
|.  ...|.||||||.|    .|.   . ..||| ||  ||..|..         ||  |. ..|.|         |.||| ..| . |  |    .|.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYD-WFETSNHNNIYIIM

EYCENGDLARYIKRHKT------DRRYIAEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDIKPGNVFLTRD------------GSIKLGDFGLCR
|||. |||  |||..|.        ... |... ..| |.| .. . |.         |..||||||| |. .. .            | .|..|||...
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK---------HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAK

SLG----ELSQAKTNV------GTPLYMAIEVLQ----KQSYT-EKADIWSLGCVIYELCALQPPFVASNMDSLK-----AKVKQGARPA-----IPAH-
..     |  ...| |      ||||||| ..||    .. |.  |.|||||||..||.   .|||.|.   ...       .... ...     .|   
HVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQF

--------YSSDLSAVIDSMLNSNFNSRPSAAELLNHRKI
         |...   |  ||  . . | |  ||.||  .
PKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_5375.AA ULK 35-301 28 2.9e-64 219.8 In-house 1-324 (324) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-324/324
Sequence Identity: 28% (96 aa)

YIFLNIIGSGSFG-KVHKVQ-SRTN--GRIFACKEIDYAKMSEKEKK--------LLVHEVNTLKELS---HEN--IVSYIDRFVERENA-KMFIVMEYC
|.  ...|.|||| ||.|    .||  . ..||| ||  ||..|...        ||  |....|.|    |.|  || ..| . |  |    .|.||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYD-WFETSNHNNIYIIMEYC

ENGDLARYIKRHKT-----DRRYIAEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDIKPGNVFLTRD------------GSIKLGDFGLCRSLGE
. |||  |||..|.       ... |... ..| |.. .. . |.         |..||||||| |  .. .            | .|..|||..... .
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHK---------HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDN

----LSQAKTNV------GTPLYMAIEVLQ----KQSYT-EKADIWSLGCVIYELCALQPPFVASNMDSLK----AKVKQG--------ARPAIPA----
      . .| |      ||||||| ..||    .. |.  |.|||||||..||.   ..||...   ...      ...|         .|  .     
NNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPK

--HYSSDLSAVIDSMLNSNFNSRPSAAELLNHRKI
  . |...   |  ||  . . | |  |..||  .
DPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_5375.AA NEK-Unclassified 74-301 38 1.1e-63 209.6 In-house 35-258 (258) Show / Hide 
Range on Protein: 74-301
Range on HMM: 35-258/258
Sequence Identity: 38% (91 aa)

KEKKLLVHEVNTLKELSHENIVSYIDRFVERENAKMFIVMEYCENGDLARYIKRHKTDRRYIAEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDI
| ||     .  |  | |  || | | |   ||||.|   .||. |.| | |..|      . |  |   ..|.  |. | |.          |.|||| 
KKKKKRQNKIIILSQLRHPHIVTYHDSFF--ENAKLFYTQDYCDGGNLDRRIQKHRKKNEPFDEGRIMQWCIQMIMAVQYIHQ---------RKIIHRDL

KPGNVFLTRDGSIKLGDFGLCRSLGE-LSQAKTNVGTPLYMAIEVLQKQSYTEKADIWSLGCVIYELCALQPPFVASNMDSLKAKVKQGAR-------PA
|| |.||| |  . .||||  | . .    |.| |||. .|. ||.|.| | .. |.|||||.|||.|.  | | . || ..  |.||.         | 
KPQNIFLTDDDTVSMGDFGISRIMDHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCEPFFDTHNMGEVYMKIKQDDNRLEEALEP-

IPAHYSSDLSAVIDSMLNSNFNSRPSAAELLNHRKI
.   || ||. ||  ||  ||. |||| |..    |
VSKTYSTDLQQVIRFMLRRNFQQRPSATEIVEQDYI
Kinase GL50803_5375.AA Ciliate-E2 35-301 23 2.9e-62 212.51 In-house 1-365 (365) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-365/365
Sequence Identity: 23% (91 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRIFACKEIDYAK-------------------MSEKEKKLLVHEVNTLK----------------ELSHENIVSYID
|.|...||.|.||.| |.. . ... || | ||  |                   |...... .  | . ..                .|.| ||. ...
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

RFVERENAKMFIVMEYCENGDLARYIK--RHKT------DRRYIAEEKIWSVFVQLLH---------------ALNYCHSLHKHDDTGTHKVIHRDIKPG
 | |  . ....|||||. |||  |||  ..|       |  |. |..|  .. |.|                ||.|.|| .        ..||||||| 
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN--------NIIHRDIKPE

NVFLTRDGSIKLGDFGLCRSLGEL--------------------------------SQAKTNVGTPLYMAIEVLQKQS---------YTEKADIWSLGCV
|...     ||. ||||.. . .                                  ...| .||| ||| |.|....         |..|.||||||..
NILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

IYELCALQPPFVASNMDSLKAKVKQGARPAIP------------------AHYSSDLSAVIDS----MLNSNFNSRPS-AAELLNHRKI
.||..  .|||          . ..     .|                   . | .    |      ||. . . |.. . ..|||  .
LYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_5375.AA TyrKc 35-301 21 7e-26 93.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 35-301
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YIFLNIIGSGSFGKVHKVQSRTNGRIFACKEID-YAKMSEKEKKLLVHEVNTLKEL--SHENIVSYIDRFVER-EN----AKMFIVMEYCENGDLARYIK
  .. ..|.| ||.|.| . .   .  | | .  .|      .. . .| . ...|  .|.|||  .   ..  .|      ..|||||...|||  |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RHKTDRRYIAEEKIWSVFVQLLHALNYCHSLHKHDDTGTHKVIHRDIKPGNVFLTRDGSIKLGDFGLCRSLGEL-------SQAKTNV--GTP--L---Y
.|. .   .  ..  |  .|     .| ||          ..||||.   |. ..... .| .||||.| ...        .  ..    |.   |    
KHRPK---LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRW

MAIEVLQKQSYTEKADIWSLGCVIYELCAL-QPPFVA-----SNMDSLKAKVKQGARPAIPAH--------YSSDLSAVIDSMLNSNFNSRPSAAELLNH
||.|....  .|.| |.|| | ...|.. . |.|         . . . ..|||| |. .|..         ....  .. .  . . ..||. .|.  |
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

RKI
...
ECF
Kinase GL50803_5375.AA Pkinase_Tyr 177-301 20 1.3e-11 39.97 Pfam 141-270 (270) Show / Hide 
Range on Protein: 177-301
Range on HMM: 141-270/270
Sequence Identity: 20% (27 aa)

NVFLTRDGSIKLGDFGLCRSL--GELS-QAKTNVGTPL-YMAIEVLQKQSYTEKADIWSLGCVIYELCAL-QPP-FVASNMDSLKAKV-KQGARPAIPAH
|. .|... .| .||||.| .   .   .....   |   || |...   .|.| |.|| | ...|.. . . | .       ..... ..| | ..| .
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPEN

YSSDLSAVIDSMLNSNFNSRPSAAELLNHRKI
 . ..  .. .  . . . ||. .|.  |...
CPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Kinase GL50803_5375.AA Pkinase_Tyr 35-129 27 9.9e-11 36.97 Pfam 1-105 (270) Show / Hide 
Range on Protein: 35-129
Range on HMM: 1-105/270
Sequence Identity: 27% (29 aa)

YIFLNIIGSGSFGKVHKVQSR----TNGRIFACKEIDYAKMSEKE--KKLLVHEVNTLKEL-SHENIVSYIDRFV-ERE-NAKMFIVMEYCENGDLARYI
 .|.  .|.|.||.|.|   .     ..   | | .   . ....  .. . .|....|.| .|.|||...   . ..| | ...|||||...|||  | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDLLDYL

KRH---K
..|   |
RKHREDK