Gene GL50803_6731 (G.lamblia)

GL50803_6731

Species: G.lamblia
Alias: GL50803_6731, GK222
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_6731.AA Protein None 637 None Fasta, JSON
GL50803_6731.kin_dom Protein Kinase Domain None 262 None Fasta, JSON

Protein domain

Protein domains of GL50803_6731.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc GL50803_6731.AA S_TKc 54-317 31 7.6e-75 255.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 54-317
Range on HMM: 1-231/231
Sequence Identity: 31% (88 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEIDYANFSEAKHKLVTFETELLSTLHHPAIAGLVELYDDTERDVLYIIMELFER--GDLKNFIKNLRIQL
||...|||.|.||.|||.| ...| |.| |.|.         . .  | ..|.  ||| |  | . ..|   | ||..||. .   |||. .||. . . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

LC--VSEAQVWFFLEQILAALCYMHDNQTDPQRPKKIIHRDIKPENIVITQDGRVKLIDFGICKELVDCSVTHTRCGTSQYAAPEVFVKKPSYDE-RIDI
|.   .| ...|.. ||. || |.|.        ..|||||.||||| ...  ..|..|||....|      .| |||  | ||||.    .|.  ..|.
LRFPFPE-HARFYMYQICCALEYCHS--------HGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDW

WALGCVAYELASSKSLFPADKAPTVAIKEVPPISLPGFSPLLAEFISSMVVINPEARHSAKQLLK-------HLQN
|..||. ||... . .||    . . .| .        || . .||. . . .|| | .| ..|.       |   
WSCGCILYEMLCGYPPFP---QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase GL50803_6731.AA Pkinase 54-315 28 8.8e-72 249.58 Pfam 1-293 (293) Show / Hide 
Range on Protein: 54-315
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEIDYANFSEAKHKLVTF--ETELLSTLHHPAIAGLVELYDDTERDVLYIIMELFERG----DLKNFIK-N
|... |||.|.||.||| .....| |.| |.|.. . .. |..  .   | ...  |.|| |  | . . |  .| .|..||. | |    ||. .|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

LRIQLLCVSEAQVWFFLEQILAALCYMHDNQTDPQRPKKIIHRDIKPENIVITQDGRV----KLIDFGICKE--LVDCSVTHTRCGTSQYAAPEVFVKKP
 .  ..  || .. |.. ||| .| |.|..        .|||||.||||| | ..| .    |..|||..|   .   | ..|.|||. |.||||  . .
RHGCFY-FSEWECKFYMYQILRGLEYCHSM--------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQ

SYDERIDIWALGCVAYELASSKSLFPAD-----KAPTVAIKEVPPISLPGFS------------------------PLLAEFISSMVVINPEARHSAKQL
 |. ..|.|..||. ||... . .|| .       . . |... .  |.  .                        . . .||...   .|. | .|.|.
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

LKH--L
|.|  .
LQHPWF
Kinase GL50803_6731.AA Ciliate-E2 54-314 24 4.9e-62 211.73 In-house 1-362 (365) Show / Hide 
Range on Protein: 54-314
Range on HMM: 1-362/365
Sequence Identity: 24% (92 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEIDYAN---------------------------FSEAKHKL---------VTFETELLSTLHHPAIAGLV
|..| |||||.||||||.......  || | ||  .                           ..  .| .            | ..|..| || |  ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMY

ELYDDTERDVLYIIMELFERGDLKNFIKNLRIQLLCV-------SEAQVWFFLEQILA---------------ALCYMHDNQTDPQRPKKIIHRDIKPEN
| . .. .. .|..||... |||. .||| ... ..        .| .. .. .|||                || |.| .        .||||||||||
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN-------NIIHRDIKPEN

IVITQDGRVKLIDFGICKELVDC--------------------------------SVTHTRCGTSQYAAPEVFVKKPS--------YDERIDIWALGCVA
|..     .|.||||..|.. |.                                 ...| |||  | |||.. .|.         ||. .|||.||.. 
ILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

YELASSKSLFPADKAPTVAIKEVPPISLP-------------------GFSPLLAEFISS----MVVINPEARHS-AKQLLKH
||. . |  |         ...  .|..|                     |.    .|.     | . .|| | . ..|.|.|
YEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNH
Kinase GL50803_6731.AA AGC 54-305 21 5.1e-60 152.84 In-house 1-373 (395) Show / Hide 
Range on Protein: 54-305
Range on HMM: 1-373/395
Sequence Identity: 21% (82 aa)

YELIDKIGQGGFGSVYKVRRR------SDGAIFASKEIDYAN-FS-----EAKHKLVTF----------ETELLSTLH----------HPAIAG-LVELY
.|..  ||.|.|| || ||..      . | ..| | .. .         . .| .. .          | . |....          || |   |   .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

DDTERDVLYIIMEL---FER-----GDLKNFIKNLRI-QLLCVSEAQVWFFLEQ-------ILAALCYMHDNQTDPQRPKKIIHRD-IKPENIVITQDGR
 | ... ||..||.   . .     |..  |. .    .  . .| .. |.. .       |. || |.|..       ..||||| .|||||....|| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSH-------MGIIHRDYLKPENILLDEDGH

VKLIDFGICKELV-DC--------------------------------------------------SVTHTRCG--TSQYAAPEVFVKKPSYDERIDIWA
.|| ||| |||.. |.                                                    |.| ||  | .| |||..     |.   |.|.
IKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWS

--LGCVAYELASSKSLFPAD-----------KAPTVAIKE------VPPISLP-----------GFSPLLAEFISSMVVINPEAR
  |||. ||. . .. | .|           .. .    .        .. .|            ||| .  .|. . . .|| |
FGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKR
Kinase GL50803_6731.AA NEK 54-317 37 2.1e-59 203.64 In-house 1-286 (286) Show / Hide 
Range on Protein: 54-317
Range on HMM: 1-286/286
Sequence Identity: 37% (108 aa)

YELIDKIGQGGFGSVYKVRRRSDGAI-----FASKEIDYANFSEAKHKLVT-FETELLSTLHHPAIAGLVELYDDTERDVLYIIMELFE-RGDLKNF---
||.| ||||| ||.||||||.||| .     .. |.|.. | || . .     |  .|. |.|| | .  . . . . . |.|.||  |  ||| ..   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

IKNLRIQLLCVSEAQVWFFLEQILAALCYMHDNQTDPQRPKKIIHRDIKPENIVITQDGR----VKLIDFGICKELV-DCSVTHT-RCGTSQYAAPEVFV
||. . .    .| |.| .. |.. || ||||.   |||  ||.|||||| || .| ...    ||. |||| |.|  ...  .|   ||  |..|||. 
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GPQR--KILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQ

KKPSYDERIDIWALGCVAYELASSKS--LFPAD--KAPTVA--IKEV-PPISLP-G--FSPLLAEFISSMVVINPEARHSAKQLLKHLQN
 || |... |||.|||| ||... |.   | |.    |  .  |..   .  .|    .|. | ..||.|   .|| | |..|.|.. . 
NKP-YNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_6731.AA STE 54-314 24 4.7e-58 199.18 In-house 1-356 (359) Show / Hide 
Range on Protein: 54-314
Range on HMM: 1-356/359
Sequence Identity: 24% (91 aa)

YELIDKIGQGGFGSVYKVRRR------SDGAI---------FASKEIDYANFS---------------EAKHKLVTFETELLSTLH--HPAIAGLVELYD
.|.|.|||.|.||.||| ...      . | .         .| |.... | .               . ... .  | .... ..  || |      | 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DTERDVLYIIMELFERGDLKNFIK-NLRIQL---------LCVSEAQVWFFLEQILAA-LCYMHDNQTDPQRPKKIIHRDIKPENIVITQDGRVK
     . ..| |.|.||. . | |  .|| .  ..           ...| |. ... ||| . | | |...        |||||||| || .     ||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--------IIHRDIKPANILL-----VK

LIDFGICKELVD-----------------CSVTHTRCGTSQYAAPEVFVK-----KPSYDERIDIWALGCVAYELASSKSLF---PADKAPTVAIKE---
|.|||.|. |.|                  . . | .||  . ||||  .     .. ||.. ||| |||.. |.|  |  .   .  .|   ....   
LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHM

-----------VPPISLPG--------------------FSPLLAEFISSMVVINPEARHSAKQLLK--H
            || .||                     .|| . .||.   ...|. | .|.||||  |
QQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEH
Kinase GL50803_6731.AA Ciliate-E2-Unclassified 54-314 24 5.8e-56 192.23 In-house 1-349 (352) Show / Hide 
Range on Protein: 54-314
Range on HMM: 1-349/352
Sequence Identity: 24% (89 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIF-----ASKEIDYA-NFSEAKHKLVTFETELLSTLH-----------------HPAIAGLVELYDDTERDVLYI
|..| .|||||||.|||.......  .     ..| ..|. .  . |.    .| . .  .                  || .  ....| .. .. .||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IMELFERGDLKNFIKN----------LRIQLLC---VSEAQVW-----FFLEQILAALCYMHDNQTDPQRPKKIIHRDIKPENIVITQDG---RVKLIDF
.||..| |||...||.          |  ....   ..| |.      |.. ||| .|.|.| .       ..|||||||||||.....|   ..|.|||
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHK-------NNIIHRDIKPENILFDNNGKNYYIKIIDF

GICKELVDC----------------SVTHTRCGTSQYA----APEVFVKKPSYD---ERIDIWALGCVAYELASSKSLFPADK-----------------
||.|.. ..                  ..|.||| .|     ||||. ..  ..   . .|||.||...||.   .  |.. .                 
GISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

-APTVAIKE----VPPISL----PGFSPLLAEFIS----SMVVINPEARHSAKQLLKH
      ||.    .|. .      . ||  ..||.    .| . ||. | ...|.|.|
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNH
Kinase GL50803_6731.AA CAMK 59-314 19 1.1e-51 164.42 In-house 1-422 (425) Show / Hide 
Range on Protein: 59-314
Range on HMM: 1-422/425
Sequence Identity: 19% (83 aa)

KIGQGGFGSVYKVRRRSDG------------AIFASKEIDYA----------------NFSEAKH----------KLVTFETELLST-------LHHPAI
..|.|.|| |.........              .| | ||                  ..|..||          | |  | |....       |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

AGLVELYDD-----------TERD-------VLYIIM---ELFERG----DLKNFIKNL-----------RIQLL-CVSEAQVWFFLEQILAALCYMHDN
  | | |.|           | ..        .|..|   |. . |    || ..|.              .    ...|... ..  ||. |. |.|..
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

QTDPQRPKKIIHRDIKPENIVITQD-----------------GRVKLIDFGICKELVD------------------------CSVTHTRCGTSQYAA-PE
        .|.|||.||||| ....                 . .|.||||  ... .                            .|.|||  |.| ||
--------NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPE

VFVK-------------KPSYDERIDIWALGCVAYELASSKSLFPAD---------------KAPTVAIKEVPPI-SLPGFSP-----------------
|. .             || |.. .|.|..|.. | . . .. | .|               .     |..       | |||                 
VLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEF

------LLAEFISSMVVINPEARHSAKQLLKH
          .|..| . .|| | ...| |.|
HHFVSQECKDLIRKMLQVDPEKRMTIEQCLNH
Kinase GL50803_6731.AA NEK2 54-260 31 2.9e-47 157.15 In-house 1-259 (319) Show / Hide 
Range on Protein: 54-260
Range on HMM: 1-259/319
Sequence Identity: 31% (84 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEIDYANFSEAKHKLVTFETELLSTLHHPAIAGLVELYD---DTERDVLYIIMELFERGDLKNFIKNLRIQ
||    ||.| ||...|||| ||| |...|||.| .  |..  .   |  .|. | || |   |. ||   | .  .|||.||  |.|||   ||  | .
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNI---VRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKE

LLCVSEAQVWFFLEQILAALCYMHD-----------NQTDPQRPK--KIIHRDIKPENIVITQDGR----------------------------------
     |  .|  . |.. ||   |                |  .    |.|||||| ||   .|.                                   
RQYMEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMD

-----VKLIDFGICKELV-DCSVTHTRCGTSQYAAPEVFVKKPSYDERIDIWALGCVAYELAS
     ||| |||  . |  | |  ||  ||  |  ||. ..  .|.|. |||..||. ||...
YSQVVVKLGDFGLARMLNHDTSFAHTFVGTPYYMSPEQ-MHGQKYNEKSDIWSVGCLIYEMCA
Kinase GL50803_6731.AA Ciliate-E2a 54-267 30 1.4e-46 135.11 In-house 1-218 (275) Show / Hide 
Range on Protein: 54-267
Range on HMM: 1-218/275
Sequence Identity: 30% (70 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEIDYANFSEAK--HKLVTFETELLSTLHHPAIAGLVELYDDTERDVLYIIMELFERGDLK-NFIKNLRIQ
|..|.|||.| |||||..... .|  || | ..   ... |   . .. |  ....| || |  | | | |     .|..||..| |.|.  .... |..
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENN--YYLVMEYCEGGELYDKIKQCKRFF

LLCVSEAQVWFFLEQIL-AALCYMHDNQTDPQRPKKIIHRDIKPENIVIT---QDG----RVKLIDFGICKEL--VDCSVTHTRCGTSQYAAPEVFVKKP
     . ..  .. |.|  .| |||         ..|.|||.||||| ..   ...     .|.||||  .     .  . ...|||  | ||||.  | 
EE---IQEICDIMQQLLWQGLHYMHQ--------RNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKE

-----SYDERIDIWALGCVAYELASSKSLFPA
     .||.  |.| .|.. | | . |..|..
VLKHKQYDTKCDMWSCGVIFYILLCGKPPFKG
Kinase GL50803_6731.AA NEK1 54-313 33 4.2e-43 147.36 In-house 1-272 (276) Show / Hide 
Range on Protein: 54-313
Range on HMM: 1-272/276
Sequence Identity: 33% (94 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEIDYANFSEAKHKLVTFETELLSTLHHPAIAGLVELYDDTERDVLYIIMELFERGDLKNFIKNLRIQLLC
|. | .||.| || ...|....||  .. |||   . .|     .  |  .|. . || | .. |      . .|||.||  . |||   |.. . .   
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKL

VSEAQVWFFLEQILAALCYMHDNQTDPQRPKKIIHRDIKPENIVIT--QDG---------------RVKLIDFGICKELVD-CSVTHTRCGTSQYAAPEV
 || |   .  ||  || ..||        .||.|||||. ||. |  ..|                ||| |||| . | .  .   |  || .|  || 
FSEDQIMHWFCQICLALNHIHD--------RKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTMEYACTCIGTPYYLSPEI

FVKKPSYDERIDIWALGCVAYELASSKSLFPADKAPTVAIK----EVPPISLPGFSPLLAEFISSMVVINPEARHSAKQLLK
  .|| |.   |||.|||| |||   |  | | . ..   |     .|||. | .|  | . .|.|  .||. | |. |.|.
CQNKP-YNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIP-PHYSYELQSLVSQMFKRNPRHRPSVNQILE
Kinase GL50803_6731.AA NEK4 54-317 33 1.3e-41 144.57 In-house 1-257 (257) Show / Hide 
Range on Protein: 54-317
Range on HMM: 1-257/257
Sequence Identity: 33% (91 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEIDYANFSEAKHKLVTFETELLSTLHHPAIAGLVELYDDTERDVLYIIMELFERGDLKNFIKNLRIQLLC
|. .  .|.| .| |. || | |.  .  | ..  | |  . |    | .||| | || |    | ..  .   |||.|   | ||| .  |  . |.| 
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQKNQFL-

VSEAQV--WFFLEQILAALCYMHDNQTDPQRPKKIIHRDIKPENIVITQDGRVKLIDFGICKELV-DCSVTHTRCGTSQYAAPEVFVKKPSYDERIDIWA
 .| ||  ||   ||  || |||.        |.|.||| |  || .|.   .|. |||| . |   | .  |  ||  |  ||.|  .| || . |||.
-EEYQVVEWFV--QIAMALQYMHE--------KHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRP-YDYKSDIWS

LGCVAYELASSKSLFPADKAPTVAIK----EVPPISLPGFSPLLAEFISSMVVINPEARHSAKQLLKHLQN
|||  ||..  |  | |   .    .      ||.. | .|. |.. .  |    |. | |  ....    
LGCCVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMP-PNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase GL50803_6731.AA TyrKc 54-315 19 4.2e-14 5.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 54-315
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

YELIDKIGQGGFGSVYKVRRRSDGAIFASKEID-YANFSEAKHKLVTFETELLSTL--HHPAIAGLVELYDDTER--------DVLYIIMELFERGDLKN
 .|..|.| | || ||| . .      | | .  .|      ..    | .... |  ||| |   | ||             . |.|.||. . ||||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNI---VRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

FIKNLRIQLLCVSEAQVWFFLEQILAALCYMHDNQTDPQRPKKIIHRDIKPENIVITQDGRVKLIDFGICKELVDC-------SVTHTR---CGTS----
.... | .   .. ..   |  || .   | |..        ..||||.   |. .. ...||  ||| .... |        .. ...   .| .    
YLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK--------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

QYAAPEVFVKKPSYDERIDIWALGCVAYELASSKSLFPAD-----KAPTVAIKEVPPISLPGFSPL------------LAEFISSMVVINPEARHSAKQL
   |||.. ..  . .  |.|. | . .|. .     . .     . .. .|. |     .   |             . . ...    .|| | . ...
RWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

LKHL
 . .
HECF
Kinase GL50803_6731.AA Ciliate-E2a 293-314 31 0.00029 8.48 In-house 251-272 (275) Show / Hide 
Range on Protein: 293-314
Range on HMM: 251-272/275
Sequence Identity: 31% (7 aa)

FISSMVVINPEARHSAKQLLKH
... |.. .|. | .|.|.|.|
LMKKMLEKDPKKRITAQQALNH
Kinase GL50803_6731.AA NEK2 290-317 32 0.131873 1.04 In-house 292-319 (319) Show / Hide 
Range on Protein: 290-317
Range on HMM: 292-319/319
Sequence Identity: 32% (9 aa)

LAEFISSMVVINPEARHSAKQLLKHLQN
| | |..|  .... | |   .|.| | 
LNEIIHFMINVDHYHRPSIEEILQHPQI
Ank GL50803_6731.AA Ank 385-406 40 0.005893 14.92 Pfam 1-22 (33) Show / Hide 
Range on Protein: 385-406
Range on HMM: 1-22/33
Sequence Identity: 40% (9 aa)

EGKTALHLAAKANKKFVAKTLI
.| |.||||.. . . |.| |.
DGFTPLHLACRCGHTEVVKMLL
Ank GL50803_6731.AA Ank 416-436 38 0.123048 10.16 Pfam 1-21 (33) Show / Hide 
Range on Protein: 416-436
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

AGSTAFSIAVKMGHTDIAEML
 | |.  .|...|||....||
DGFTPLHLACRCGHTEVVKML
Ank GL50803_6731.AA Ank 490-520 36 8.8e-07 28.72 Pfam 1-33 (33) Show / Hide 
Range on Protein: 490-520
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

DGMTALMHAAQNGNTDCCKMLLE--AESGVANR
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DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_6731.AA Ank 457-489 33 0.000559 18.61 Pfam 1-33 (33) Show / Hide 
Range on Protein: 457-489
Range on HMM: 1-33/33
Sequence Identity: 33% (11 aa)

FGMTPLMWAAITNDVGSVSVCLAKGLYVGLQDH
 |.|||..|.. ...  |.  | .|  | .|| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_6731.AA Ank 521-553 21 0.00751 14.54 Pfam 1-33 (33) Show / Hide 
Range on Protein: 521-553
Range on HMM: 1-33/33
Sequence Identity: 21% (7 aa)

RGETALFFAVAADHVDIIDLLFEKEATISVRAA
 |.|.|  |.  .|.... .| .. | . ..  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_6731.AA Ank 556-577 31 34.269788 1.34 Pfam 1-22 (33) Show / Hide 
Range on Protein: 556-577
Range on HMM: 1-22/33
Sequence Identity: 31% (7 aa)

GHRTILEAASFVGNMDVISRLL
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DGFTPLHLACRCGHTEVVKMLL