Gene GL50803_8152 (G.lamblia)

GL50803_8152

Species: G.lamblia
Alias: GL50803_8152, GK165
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_8152.AA Protein None 581 None Fasta, JSON
GL50803_8152.kin_dom Protein Kinase Domain None 265 None Fasta, JSON

Protein domain

Protein domains of GL50803_8152.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_8152.AA NEK 13-277 35 6.3e-85 288.46 In-house 1-286 (286) Show / Hide 
Range on Protein: 13-277
Range on HMM: 1-286/286
Sequence Identity: 35% (104 aa)

YEIIGFLGQGQFGAVHKVKSKTSGQI-----YACKIMRYENMSRKEKQLLH-SEINLHKKLSHKNIVQYYRTILGEESKEIYLLTEYCG-KGDLLKF---
||||  .|||.|| |.||..|  |..     |. | . ..|||.|||| .  .|... |.| | ||| ||  .. |..  ..   |||  .||| ..   
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

VKEYP--QKIIPEATIWNIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDGC----IKLCDFGFSKSCGLN-EVAVT-ILGSPMYTAPELF
 |..    | ..| .||... |.. ||.|.|.    .      |.||||||.|. . ....    .|. ||| ||  . . . | |   | | | .||..
IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRK-GP---QRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVC

KRQPYNEKADIWSLGCVMHHVCTRAV--PFIAT--TKEGLTKQILED-QRTPLPSQ--YSKELVKFLQSMITQDPDKRPSASELLLCPKF
. .|||.|.||||||||  . ||     || |.    ..| ..| .  |  |.||.  ||..| .....|.. ||..|||....|  |  
QNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI
Kinase GL50803_8152.AA S_TKc 13-278 31 1.1e-76 262.02 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-278
Range on HMM: 1-231/231
Sequence Identity: 31% (87 aa)

YEIIGFLGQGQFGAVHKVKSKTSGQIYACKIMRYENMSRKEKQLLHSEINLHKKLSHKNIVQYYRTILGEESKEIYLLTEYCGK--GDLLKFVKEYPQ--
|||.  .|.| || |.|.. | .|.|.|.||..         . . .||...||  |.|||..| ..     ...|. .|||.   |||... |...   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

--KIIPEATIWNIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDGCIKLCDFGFSKSCGLNEVAVTILGSPMYTAPELFKRQPYNE-KADI
  . .|| ... .| |...||.||||  .        |||||.||.|.|. .  .||.||||...         |. |.| | |||..   .|.  |.|.
LRFPFPE-HARFYMYQICCALEYCHSH-G--------IIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDW

WSLGCVMHHVCTRAVPFIATTKEGLTKQILEDQRTPLPSQYSKELVKFLQSMITQDPDKRPSASELLL------CPKFK
||.||..   ...  ||   . . . |.|.           |.|.  |.. . . ||.|||.| |.|       |  . 
WSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_8152.AA NEK2 13-277 34 1.1e-75 254.37 In-house 1-319 (319) Show / Hide 
Range on Protein: 13-277
Range on HMM: 1-319/319
Sequence Identity: 34% (110 aa)

YEIIGFLGQGQFGAVHKVKSKTSGQIYACKIMRYENMSRKEKQLLHSEINLHKKLSHKNIVQYYRTILGEESKEIYLLTEYCGKGDLLKFVKEYPQ--KI
||. . .|.| || . ||. |  | | . | . |..|  ||.|.| ||.|. ..| | |||.||  |  .... .|.  |||  |||   .| . .  . 
YEVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQY

IPEATIWNIMGQLLQALQYCHS----PT--------KPGFDYGTVIIHRDIKPANVLIRDDGC-------------------------------------
..|  || || ||. ||| ||     ||        ||  | . .|.||||||||.    |.                                      
MEEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHTILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQ

--IKLCDFGFSKSCGLN---EVAVTILGSPMYTAPELFKRQPYNEKADIWSLGCVMHHVCTRAVPFIATTKEGLTKQILEDQRTPLPSQYSKELVKFLQS
  .|| |||  ..  ||     | |  | | |  ||. ..|.|||| ||||.||.    |.   || ||    |.  | .    ..|.|||..| .   .
VVVKLGDFGLARM--LNHDTSFAHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEIIHF

MITQDPDKRPSASELLLCPKF
||  |. .|||  |.|  |  
MINVDHYHRPSIEEILQHPQI
Kinase GL50803_8152.AA STE 13-277 25 9.5e-70 238.03 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-277
Range on HMM: 1-359/359
Sequence Identity: 25% (95 aa)

YEIIGFLGQGQFGAVHKVKSKT---------------SGQIYACKIMRYENMS---------------RKEKQLLHSEINLHKKLS--HKNIVQYYRTIL
.|.|...|.| || |.| . .                .|.|.| |.|..|| .                .|.| .  ||...||..  |.|||.|| . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

GE---ESK--EIYLLTEYCGKGDLLKFVK---EYPQ---------KIIPEATIWNIMGQLLQA-LQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDGCI
 |   ..   |...  ||.. | | ...|   . ..         . .||  |  |  |.|.. |.| ||        .  ||||||||||.|.     .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS-------HH--IIHRDIKPANILL-----V

KLCDFGFSKSCGLN-----------------EVAVTILGSPMYTAPELFKR------QPYNEKADIWSLGCVMHHVCTRAVPF---IATTKEGLTK----
||||||....   .                 .   |. |.| . |||  ..      ..|..|.|||||||.. . .|  .|.     .    ..     
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

--------QILEDQRTPLPS-------------------QYSKELVKFLQSMITQDPDKRPSASELLL--CPKF
        .|....  |||.                   ..|.|.  |..   . ||.|||.||.||    | .
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_8152.AA Pkinase 13-277 29 1.8e-68 238.55 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-277
Range on HMM: 1-293/293
Sequence Identity: 29% (91 aa)

YEIIGFLGQGQFGAVHKVKSKTSGQIYACKIMRYENMSRKEKQLLHS--EINLHKKLSHKNIVQYYRTILGEESKEIYLLTEYCGKG----DLLKFVKEY
|.|.. .|.| || | | . | .|.|.|.||..... . ...| .    || ..|.|.|.|||..|..     ...||. .|||..|    ||  ...  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTW

PQKII--PEATIWNIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDGCI----KLCDFGFSKS--CGLNEVAVTILGSPMYTAPELFK-RQ
 .. .  .| .. ..| |.|..|.||||           |||||.||.|.|| ..| |    |.||||..|      |. . |. |.| | |||. . .|
RHGCFYFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQ

PYNEKADIWSLGCVMHHVCTRAVPFIAT----TKEGLTKQILEDQRTPLPSQYS-----------------------KELVKFLQSMITQDPDKRPSASE
.|  |.|.||.||... ....  ||       .     . | .. ..||.....                       .|. .|. .....|| |||.| .
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

LLLCPKF
.|  | |
ILQHPWF
Kinase GL50803_8152.AA ULK 13-265 27 2.7e-63 216.6 In-house 1-317 (329) Show / Hide 
Range on Protein: 13-265
Range on HMM: 1-317/329
Sequence Identity: 27% (91 aa)

YEIIGFLGQGQFGAVHKVK-SKTS---GQIYACKIMRYENMSRKEKQ--------LLHSEINLHKKLS----HKN----IVQYYRTILGEESKE--IYLL
|...  ||.|.|| |.| .  ||    ....|||..  . |..|...        || .|| . |||     |||    ||..|     |.|..  ||. 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYD--WFETSNHNNIYII

TEYCGKGDLLKFVKEYPQ--------KIIPEATIWNIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDD------------GCIKLCDFGFS
.|||  ||| .. |..          |...|  . ... |.|..... |.           ||||||||.|.|| ..            |..|..||||.
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHK---------HNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA

KSCGLN----EVAVTIL------GSPMYTAPELFK----RQPYN-EKADIWSLGCVMHHVCTRAVPFIATTKEGLTKQILEDQ------------RTPLP
|..  .    ....| .      |.|.| ||....    ..||.  |.|||||||...   .  .|| |  .. . .||...              .|| 
KHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQ

-------SQYSKELVKFLQSMITQDPDKR
        | |.|.  ... |.. |...|
FPKDGNDPQISPECKDLIRRMLQYDEKDR
Kinase GL50803_8152.AA Ciliate-E2 13-277 24 1.7e-61 209.85 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-277
Range on HMM: 1-365/365
Sequence Identity: 24% (95 aa)

YEIIGFLGQGQFGAVHKVKS-----------------------KTSGQIYACKIMRYE--NMSRKEKQLLH---------SEINLHKKLSHKNIVQYYRT
|..|  .|||.|| | |.|                        |. ..||| |||.    ..  .|....           | |. ..|.|.||...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

ILGEESKEIYLLTEYCGKGDLLKFVKEYPQKI---------IPEATIWNIMGQLLQ---------------ALQYCHSPTKPGFDYGTVIIHRDIKPANV
   .  . ||| .|||  |||... |. ..|          . |  | .|| |.||               ||.|.||        .  |||||||| |.
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHS-------KNN-IIHRDIKPENI

LIRDDGCIKLCDFGFSKSCGLN--------------------------------EVAVTILGSPMYTAPELFKRQP---------YNEKADIWSLGCVMH
|.     ||..|||.|| .  .                                ... ||.|.|.| ||| .....         |..|.||||||....
LF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILY

HVCTRAVPFIATTKEGLTKQILEDQRTPLP------------------SQYSKELVKFLQS----MITQDPDKRPS-ASELLLCPKF
  ..   ||          |. ...   .|                   . |.|   ...     |.  ||.||.. ....|  | |
EMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_8152.AA CAMKL 13-272 28 2.8e-60 191.01 In-house 1-292 (297) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-292/297
Sequence Identity: 28% (86 aa)

YEIIGFLGQGQFGAVHKVKS-KTSGQIYACKIMRYENMSRKEKQL-------------LHSEINLHKKLS---HKNIVQYYRTILGEES----KEIYLLT
|.|.  ||.| || |   .  .| |. .| ||.  . .. ... .             .  ||...|.|.   |.||.. | .|  .|     |.||| .
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYCGKGD--LLKFVKEYPQKI--IPEATIWNIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDG--CIKLCDFGFSKSCG-L----NEVAV
|||. |.  |. .... . .   .||     .  |.. |..||||           |.|||||| |.|. ..|   ||..|||||  .       ..   
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHS---------HGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLK

TILGSPMYTAPELFKR--QPYN-EKADIWSLGCVMHHVCTRAVPFIATT--------KEGLTKQILEDQRTP-LPSQYSKELVKFLQSMITQDPDKRPSA
|  ||| | |||.|..  .||.  |.||||.| ..    . ..|| . |        .  | ..| ..   |  ... | ..  ....| . .|.|||..
TFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI

SELL
 ...
HQIM
Kinase GL50803_8152.AA Ciliate-E2-Unclassified 13-277 24 4.4e-59 202.61 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-277
Range on HMM: 1-352/352
Sequence Identity: 24% (89 aa)

YEIIGFLGQGQFGAVHKVKSKTSGQI----YACKIMRYE--NMSRKEKQLLHSEINLHKK----------------LSHKNIVQYYRTILGEESKEIYLL
|.||  .|||.|| |.|.. |  .|.    |..||. |   .. .|. ... ... . .|                |.|.... ..     .  . ||. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TEYCGKGDLLKFVKEYPQ---------------KIIPEATIW-----NIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDG---CIKLCDF
.|||  |||... |....               ||..|  .      ... |.||.|.|.|.  .        |||||||| |.|. ..|   .||..||
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNN--------IIHRDIKPENILFDNNGKNYYIKIIDF

GFSKSCGLN----------------EVAVTILGSPMYT----APELFKRQPYN----EKADIWSLGCVMHHVCTRAVPFIATTKEG--------------
|.||  . |                . . |. |.|.|     |||....| |.    .|.||||||....  ..   || ....|               
GISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

--LTKQILEDQRTPLP----------SQYSKELVK-FLQSMITQDPDKRPSASELLLCPKF
  | ..|.. .    .          |.  |.... .||.|.  .|.||......|  | |
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_8152.AA MARK 13-272 32 8.8e-58 187.52 In-house 1-257 (262) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-257/262
Sequence Identity: 32% (88 aa)

YEIIGFLGQGQFGAVHKVKSKTSGQIYACKIMRYENMSR-KEKQLLHSEINLHKKLSHKNIVQYYRTILGEESKE-IYLLTEYCGKGDLLKFVKEYPQKI
|...  .|.| .. | .. .| .|. .| ||.  ..... .... . .||...|||.|.||.... .|  ....  |||  ||...|.|. ..|. |   
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

IPEATIWNIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDG--CIKLCDFGFSKSCGLNEVAVTILGSPMYTAPELFKRQPYN-EKADIWS
..|     |  |.. |..||||           |.|||||| |.|| ..|   ||..|||||  .  ..   |  |.| | |||.|...||.  |.||||
LHEEEARRIFRQIVSAVNYCHS---------KNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWS

LGCVMHHVCTRAVPFIATT--KEGLTKQILEDQRTPLPSQYSKELVKFLQSMITQDPDKRPSASELL
|| |.    .  .|| ..|   . | |.||  . .  |.  |||. ...|...| .|..||...|..
LGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIM
Kinase GL50803_8152.AA ULK 144-265 26 2.4e-36 126.51 In-house 147-312 (324) Show / Hide 
Range on Protein: 144-265
Range on HMM: 147-312/324
Sequence Identity: 26% (44 aa)

IIHRDIKPANVLIRDD------------GCIKLCDFGFSKSCGLN----EVAVTIL------GSPMYTAPELFK----RQPYN-EKADIWSLGCVMHHVC
||||||||.| || ..            |..|..||||.|..  |     .  |..      |.|.| ||....    ..||.  |.|||||||...   
IIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEML

TRAVPFIATTKEGLT-------------KQILEDQRTPLP-----SQYSKELVKFLQSMITQDPDKR
.  .|| .  .. .              . . ..|  . |      . |.|.  ... |.. |...|
YGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDR
Kinase GL50803_8152.AA CAMK 144-277 18 3.4e-35 110.33 In-house 200-425 (425) Show / Hide 
Range on Protein: 144-277
Range on HMM: 200-425/425
Sequence Identity: 18% (42 aa)

IIHRDIKPANVLIRDD-----------------GCIKLCDFGFSKSCGL------------------------NEVAVTILGSPMYTA-PELFKR-----
|.|||.|| |.|. |.                 . ||..||||.. .                          ..   |  |.| | | ||....     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QPYNEKADIWSLGCVMHHVCTRAVPFIAT-------------TKEGLTKQILEDQRTPLPSQYSK-----------------------ELV
         ..|..|.|.||.|...    .   || .              . . | ..|.. . .  |.. |.                       |  
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

KFLQSMITQDPDKRPSASELLLCPKF
 ....| . ||.||..... |  | .
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase GL50803_8152.AA CAMK 18-132 19 8.3e-27 82.81 In-house 1-197 (425) Show / Hide 
Range on Protein: 18-132
Range on HMM: 1-197/425
Sequence Identity: 19% (39 aa)

FLGQGQFGAVHKVKSK-TSG-----------QIYACKIMRYENMS--------------------------RKEKQLLHSEINLHKKLS-------HKNI
 ||.|.|| |.... | | |           | .|.||.  . ..                           | .. . .||...|||.       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYYRTILGEE-----------------SKEIYLLT---EYCGKG----DLLKFVKEYPQ-------------KIIPEATIWNIMGQLLQALQYCHS
.. | ..  ..                  |..|. .   |||  |    ||. ...| ..             . ..|.    .. |...|..||||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS
Kinase GL50803_8152.AA ULK 13-129 29 5.7e-24 81.97 In-house 1-141 (324) Show / Hide 
Range on Protein: 13-129
Range on HMM: 1-141/324
Sequence Identity: 29% (42 aa)

YEIIGFLGQGQFG-AVHKVK-SKTS--GQIYACKIMRYENMSRKEKQ--------LLHSEINLHKKLS---HKN--IVQYYRTILGEES--KEIYLLTEY
|...  ||.|.||  |.| .  ||   .|..|||..   .|. |...        || .||.. |||    |.|  ||..|     |.|  . ||. .||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYD--WFETSNHNNIYIIMEY

CGKGDLLKFVKEYPQ-------KIIPEATIWNIMGQLLQALQY
|  ||| .. |..         |...|  . ... |.......
CNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKE
Kinase GL50803_8152.AA TyrKc 13-277 20 3.8e-17 54.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-277
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

YEIIGFLGQGQFGAVHKVKSKTSGQIYACKIMRYENMSRKEKQLLHSEINLHKKL--SHKNIVQYYRTILGE-----ESKEIYLLTEYCGKGDLLKFVKE
 . .  || |.|| |.| . |   .  | | .. .      .. ...|... .||  .|.|||. |  .. .     ... .....||. .|||... ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YPQKIIPEATIWNIMGQLLQALQYCHSPTKPGFDYGTVIIHRDIKPANVLIRDDGCIKLCDFGFSKSCGLN------EVAVTILG--SPM------YTAP
.  | .. ..  ... |  .  .| ||           .||||.   |.|. .....| .||| |.  .        .   .  .  .         .||
HRPK-LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

ELFKRQPYNEKADIWSLGCVMHHVCTR-AVPFIA-----TTKEGLTKQILEDQRTPLPSQ--------YSKELVKFLQSMITQDPDKRPSASELLLCPKF
| ..   ...| |.|| | .|  ..|. . |         . . . ... .  | | |           ..|. .  ..    ||..||. ||.  . .|
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_8152.AA Pkinase_Tyr 13-110 26 4e-10 34.91 Pfam 1-108 (270) Show / Hide 
Range on Protein: 13-110
Range on HMM: 1-108/270
Sequence Identity: 26% (29 aa)

YEIIGFLGQGQFGAVHKVKSK----TSGQIYACKIMRYENMSRKE--KQLLHSEINLHKKL-SHKNIVQYYRTIL-GEESKEIYLLTEYCGKGDLLKFVK
 ...  ||.|.|| |.| . |      ..  | |..  |. . ..  .. . .|... |.| .|.|||..|  ..  .|...||. .||. .||||.. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EY---PQKI
.    .|..
KHREDKQPL
Kinase GL50803_8152.AA Pkinase_Tyr 144-168 44 0.045156 7.64 Pfam 132-156 (270) Show / Hide 
Range on Protein: 144-168
Range on HMM: 132-156/270
Sequence Identity: 44% (11 aa)

IIHRDIKPANVLIRDDGCIKLCDFG
.||||.   |.|. .....| ||||
CIHRDLAARNCLVTENNVVKICDFG
Kinase GL50803_8152.AA Pkinase_Tyr 189-277 25 0.089121 6.64 Pfam 181-270 (270) Show / Hide 
Range on Protein: 189-277
Range on HMM: 181-270/270
Sequence Identity: 25% (23 aa)

TAPELFKRQPYNEKADIWSLGCVMHHVCTRA-VP-FIATTKEGLTKQI-LEDQRTPLPSQYSKELVKFLQSMITQDPDKRPSASELLLCPKF
.||| ..   ...| |.|| | .|  ..|.   | .   . | . ..|  . .| | |   ..|. . ...   .||..||. ||.    ..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL
Ank GL50803_8152.AA Ank 432-462 30 0.000414 19.08 Pfam 1-33 (33) Show / Hide 
Range on Protein: 432-462
Range on HMM: 1-33/33
Sequence Identity: 30% (10 aa)

KGETALMFAAANGYDACVKLLIE--DEAGIQDK
 |.|.|. |. .|.  .||.|..   .  .||.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_8152.AA Ank 401-431 42 0.000464 18.9 Pfam 1-33 (33) Show / Hide 
Range on Protein: 401-431
Range on HMM: 1-33/33
Sequence Identity: 42% (14 aa)

HGMTGLHIAARGGDTDQVKKLLS--ADAGKKTS
.|.| ||.|.| |.|. || ||.  ||   .. 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank GL50803_8152.AA Ank 463-483 38 0.015158 13.44 Pfam 1-21 (33) Show / Hide 
Range on Protein: 463-483
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

YGGTALMRAAMNGHLGAVRLL
.| |.|. |...||.  |..|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_8152.AA Ank 494-514 38 0.002636 16.18 Pfam 1-21 (33) Show / Hide 
Range on Protein: 494-514
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

RGETAMMYAAYYGHLTIVKEL
 |.|. ..|...||. .||.|
DGFTPLHLACRCGHTEVVKML
Ank GL50803_8152.AA Ank 525-547 34 0.005389 15.06 Pfam 1-23 (33) Show / Hide 
Range on Protein: 525-547
Range on HMM: 1-23/33
Sequence Identity: 34% (8 aa)

DGTTALMMAIAGNSQSCVDFLLK
|| |.|..|.  .. ..| .||.
DGFTPLHLACRCGHTEVVKMLLQ
Ank GL50803_8152.AA Ank 556-576 38 2.756114 5.29 Pfam 1-21 (33) Show / Hide 
Range on Protein: 556-576
Range on HMM: 1-21/33
Sequence Identity: 38% (8 aa)

SGETPLQLARAMGNQHLADLL
 |.||| ||  .|.   . .|
DGFTPLHLACRCGHTEVVKML