Gene GL50803_8587 (G.lamblia)

GL50803_8587

Species: G.lamblia
Alias: GK003, GL50803_8587
External Links: GiardiaDB ,
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_8587.AA Protein None 482 None Fasta, JSON
GL50803_8587.kin_dom Protein Kinase Domain None 318 None Fasta, JSON

Protein domain

Protein domains of GL50803_8587.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_8587.AA AGC 74-391 26 1.5e-140 365.88 In-house 1-395 (395) Show / Hide 
Range on Protein: 74-391
Range on HMM: 1-395/395
Sequence Identity: 26% (116 aa)

FEKIKMLGKGAFGSVWLVREK------STQKYFAMKQLCKDE---MIRRGQVEHCITE------------KEIMASSV----------SDWIIR-LYYSF
|| .|..|||.|| |.|||.|      .|.||.||| | |..   .... .||| .||            ..|..             ...|.. |.|||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDDLY--LYLVMEFAI---------GG-DLMGLLI---RVDLFPEPVARFYMSQ-------CCACINEIHK-NNSFYRD-AKPDNFLISESGHVKLSDFS
||. .  ||.|||...         || .|.  |    .   |.|..||||...        . ..  .|. ..  .||  ||.| |. | ||.||.|| 
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKDFKSRPGT---------------------MEVTTMSDEHLGTGSINPLASPTLSPGLSGTASSLRSEATGSITAPSMTVPDNVGIMHNR--------
|.| ......                      |. | .                                          .  ..  ...|.        
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMD-T-N------------------------------------------K-CNPNNWQRNNMSQEDDTT

------AYSTVG--TLDYSAVEIVRKDPGGYGHKVDWWS--MGAILYECVFGYPPFGSDNPR----------DSVKKIVKY----KQYLKFP--------
      ... .|  | .| | ||.      ||. .||||  .|...|| ..||||| .|||           .  .|| ..    .. .|||        
RKKRDRTWTFCGPCTPEYMAPEIL------YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFP

ADPKVSPECIDLIKHLIC-EPEERYD----------FEQIKAHPWF
.|...|||. ||||.|.| .||.|            .|.||.||||
EDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase GL50803_8587.AA NDR 74-391 38 6.6e-124 384.25 In-house 1-350 (350) Show / Hide 
Range on Protein: 74-391
Range on HMM: 1-350/350
Sequence Identity: 38% (137 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSV--SDWIIRLYYSFQDDLYLYLVMEFAIGGDLMG---LLIRVDL
||.|| .|||||| |||||.|.|....||| . | ||... || |  .|..|||..   ..|. .|||||||. |||||||. .|||.|    ||.. | 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FPEPVARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDFSLAKD------FKSRPGTMEVTTMSDEHLGTGSINPLASPTLSPGLSGTASS
|.| .||||.. .  .|. .||..   || |||||||   ||.||.|| |..        |.   . ..|| |     |  .    .  ....... . .
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYS-----T--FHWTHNSWYYQNMKEHRPQ

LRSEATGSITAPSMT---------VPDNVGIMHNR---------AYSTVGTLDYSAVEIVRKDPGGYGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVK
 ..... |   .. .         .  || . .||         ||||||| || |.|.. .  .||.. .|||| |.|.||...||||| ||.|..  .
DFMDNWNSNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQ-KTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCM

KIVKYKQYL-----KFPADPKVSPECIDLIKHLIC-EPEERYD-----FEQIKAHPWF
|| ..||..      ||.. ..|||. |||. |.| .|..|       ...||.||.|
KIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase GL50803_8587.AA AktR 74-391 33 4.2e-82 279.06 In-house 1-268 (268) Show / Hide 
Range on Protein: 74-391
Range on HMM: 1-268/268
Sequence Identity: 33% (110 aa)

FEKIKMLGKGAFGSVWLVREK-STQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSVSD-WIIRLYYSFQDDLYLYLVMEFAIGGDLMGLLIRVDLFPE
|. .|.||||||| | ||..|  .||..||| . | ..|.| | .|.|||. ||.. ..   |..|.|.||.. .|...||.  ||.|   | .   | |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PVARFYMSQCCACINEIHKN-NSFYRDAKPDNFLISESGHVKLSDFSLAKDFKSRPGTMEVTTMSDEHLGTGSINPLASPTLSPGLSGTASSLRSEATGS
 .||||..| . ..   |.. |  ||| ||.| |. | ||||..|| |.|                                                  
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------------------------------------------

ITAPSMTVPDNVGIMHN--RAYSTVGTLDYSAVEIVRKDPGGYGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKYKQYLKFPADPKVSPECIDL
            ..||.  .||| .||  | | |...|   |..  ||||. |. .|| |.|.||| ..| .. ..|| ..   .|||  ...|..| ||
----------LQFMMHYDEKAYSFCGTPEYMAPEMITKK-KGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDL

IKH--LICEPEERY-----DFEQIKAHPWF
|.   |   |..|      ..|.|| ||||
IQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase GL50803_8587.AA S_TKc 74-391 28 1.4e-81 278.22 SMART 1-231 (231) Show / Hide 
Range on Protein: 74-391
Range on HMM: 1-231/231
Sequence Identity: 28% (94 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSVSDWIIRLYYSFQDDLYLYLVMEFAIG--GDLMGLLIRVDL---
.|... .||||||.|...|.|.|....|.|..           || . | .|. .   ..|..||..|||  .||.|||.. |  |||. .. .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPEPVARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDFSLAKDFKSRPGTMEVTTMSDEHLGTGSINPLASPTLSPGLSGTASSLRS
   ||| .||||| | |  .. .|...  .|| ||.| |..|  |.|..|| ||. .                                           
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------------------

EATGSITAPSMTVPDNVGIMHNRAYSTVGTLDYSAVEIVRKDPGGYGH-KVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKYKQYLKFPADPKVSPE
                        .. .||..| | |..     |||. |.|||| | ||||.. |||||   ..    |||.              |||
------------------------TTFCGTPWYMAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPE

CIDLIKHLIC-EPEERYDFEQIKA-------HPWF
..|.|... . .||.|.   .. .       ||||
AKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_8587.AA RSK 77-391 27 8.5e-75 254.81 In-house 1-278 (278) Show / Hide 
Range on Protein: 77-391
Range on HMM: 1-278/278
Sequence Identity: 27% (92 aa)

IKMLGKGAFGSVWLVREK---STQKYFAMKQLCKDEMIRRGQ-VEHCITEKEIMASSV-SDWIIRLYYSFQDDLYLYLVMEFAIGGDLMGLLIRVDL---
.|.||.|..|.| |.|..    |....|||.| | ....|   ..|. || .|.. .  .  |..|.|.||....|||.||.  ||.|   | .      
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPEPVARFYMSQCCACINEIHKNNSFYRDAKPDNFLISE---SGHVKLSDFSLAKDFKSRPGTMEVTTMSDEHLGTGSINPLASPTLSPGLSGTASSLRS
| |  |.|||..    .  .|.    .|| ||.| |  .   .||.||.|| ..| |                                           
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-------------------------------------------

EATGSITAPSMTVPDNVGIMHNRAYSTVGTLDYSAVEIVRK--DPGGYGHKVDWWSMGAILYECVFGYPPFGS---DNPRDSVKKIVKYKQYLKFPADPK
                .  . ..... ..|..| | |....   .||... .|||| |...||  .|.||| .   .|. .  |.| | |  |..|....
----------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQY

VSPECIDLIKHLIC-EPEERYD-----FEQIKAHPWF
.|.|. |||... . .|. |.       |.||.||||
LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase GL50803_8587.AA Ciliate-E2 74-391 23 9.1e-72 244.74 In-house 1-365 (365) Show / Hide 
Range on Protein: 74-391
Range on HMM: 1-365/365
Sequence Identity: 23% (100 aa)

FEKIKMLGKGAFG-----SVWLVRE------------------KSTQKYFAMKQLCKDEMIRRGQVEHCI----------TEKEIMASSVSDWIIRLYYS
...||..|.|.||     .||.|..                  | ..|..|||.. |.. .   |..| .           ||.|. .  .. ||..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DDLYLYLVMEFAIGGDLMGLLIRVDLFP-----------EPVARFYMSQCCA---------------CINEIHKNN-SFYRDAKPDNFLISESGHV
||  || ..|||||.. ||||. ...  ...            |  ....| | .                .....|..|  ..|| ||.| |.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLSDFSLAKDFKSR----------------------PGTMEVTTMSDEHLGTGSINPLASPTLSPGLSGTASSLRSEATGSITAPSMTVPDNVGIMHNRA
|..|| |.|...                        || |.        .                                            |  | .
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD--------Q-------------------------------------------IIQQNMF

YSTVGTLDYSAVEIVR-KDPGG------YGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKYKQYLKFP----------------ADPKVSPECI
....||. | | ||.. |. ..      |..|.|.||.| ||||..||.|||           . . .. ..||                   |.|.||.
NTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECK

DLIKH-----LICEPEERYD-FEQIKAHPWF
||||      | ..||.|.. .|||. ||||
DLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase GL50803_8587.AA DMPK 74-216 44 6.4e-71 174.13 In-house 1-144 (270) Show / Hide 
Range on Protein: 74-216
Range on HMM: 1-144/270
Sequence Identity: 44% (64 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSVSDWIIRLYYSFQDDLYLYLVMEFAIGGDLMGLLIRVD-LFPEP
|| .|  |.|.|| | .||.|.|.. .||| . |.||. | ..     |. ||. . | ||..|.| |||. |||.|||. .||||  |. | .  .|| 
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

VARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDF
 ||||     . |. ||.     || |||| |.. .||.|| ||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADF
Kinase GL50803_8587.AA RSK-Unclassified 74-221 43 4.5e-57 177.57 In-house 1-150 (283) Show / Hide 
Range on Protein: 74-221
Range on HMM: 1-150/283
Sequence Identity: 43% (65 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSVSDWIIRLYYSFQDDLYLYLVMEFAIGGDLMGLLI--RVDLFPE
|.|....|.| || |.|||.| ||. .||| | |..|||.  .   .||..||| .    |..||.|||   ||||.||.  |||.   |   .   | |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

PVARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDFSLAKD
  .|||.|   |     ||    ||| |||| .   .|||.|.|| | ..
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQ
Kinase GL50803_8587.AA MAST 74-220 40 5.1e-55 175.65 In-house 1-147 (334) Show / Hide 
Range on Protein: 74-220
Range on HMM: 1-147/334
Sequence Identity: 40% (60 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSVSDWIIRLYYSFQDDLYLYLVMEFAIGGDLMGLLIRVDLFPEPV
|| ||...|||.| |.||. |.| . |||| ..|..||.. .|.. ..|. | | . ....  ..|||| . ||..|||. .|||.  ||  .  |.|. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDFSLAK
|..|...   |.  .|.     || |||| ||. .||.|| || |.|
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase GL50803_8587.AA ROCK 74-216 48 1.3e-50 170.53 In-house 1-142 (263) Show / Hide 
Range on Protein: 74-216
Range on HMM: 1-142/263
Sequence Identity: 48% (69 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSVSDWIIRLYYSFQDDLYLYLVMEFAIGGDLMGLLIRVDLFPEPV
|. ||..|.|||| | |||.||..| .||| | |.|||.|        |..|||   |.||..|.| |||| |||.||..  ||||. |.   |. ||  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNYDV-PEKW

ARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDF
||||       .. ||      || |||| |....||.|| ||
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADF
Kinase GL50803_8587.AA GEK 74-216 42 8.5e-46 151.49 In-house 1-144 (269) Show / Hide 
Range on Protein: 74-216
Range on HMM: 1-144/269
Sequence Identity: 42% (61 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASSVSDWIIRLYYSFQDDLYLYLVMEFAIGGDLMGLLIR-VDLFPEP
|| .|..|.|||| |  |. |.|.. .||| | | ||..|. .     |....    . || .| | |||. ||||||.. .||||. || .  |  || 
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

VARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDF
.||||..     |. .|. .   || |||| |. . ||..| ||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADF
Kinase GL50803_8587.AA DMPK 293-391 40 2.3e-41 99.37 In-house 162-270 (270) Show / Hide 
Range on Protein: 293-391
Range on HMM: 162-270/270
Sequence Identity: 40% (44 aa)

VGTLDYSAVEIVRKDPGG----YGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKY-KQYLKFPADPK--VSPECIDLIKHLICEPEERYD---F
||| || . |. .   ..    ||  .||||.| ..|| ..|  ||  |.  .   ||. . |  |.||.|||  ||.|  |||. |.|..|||     .
VGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGY

EQIKAHPWF
|..|.||.|
EDFKCHPFF
Kinase GL50803_8587.AA Pkinase 74-229 31 1.8e-31 112.4 Pfam 1-168 (293) Show / Hide 
Range on Protein: 74-229
Range on HMM: 1-168/293
Sequence Identity: 31% (54 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCI-TEKEIMASSVSDWIIRLYYSFQDDLYLYLVMEFAIGG----DLMGLLI--RV
..... .|.|.||.|.. ..|.|.| .|.|...|..     ...|   .| .||..  .. |.|||..|.|. ..|.|||.. ||    ||. ..   | 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DLF--PEPVARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHV----KLSDFSLAKDF-KSRPGTM
  |  .| ...||| | .  .. .|...  .|| ||.|.||.. ||.    |..|| ||| |   . . |
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-M
Kinase GL50803_8587.AA GEK 293-391 37 2.3e-23 74.9 In-house 162-269 (269) Show / Hide 
Range on Protein: 293-391
Range on HMM: 162-269/269
Sequence Identity: 37% (40 aa)

VGTLDYSAVEIVR---KDPGGYGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKYKQYLKFPADPK---VSPECIDLIKHLICEPEERY---DFE
||| || . ||..      | || . ||||.| ..|| ..|  || ..   .   ||...|. ..||.. .   || |  |||..|||..|.|      .
VGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQ

QIKAHPWF
  | ||.|
DFKKHPFF
Kinase GL50803_8587.AA Pkinase 293-391 32 2.2e-22 80.26 Pfam 172-293 (293) Show / Hide 
Range on Protein: 293-391
Range on HMM: 172-293/293
Sequence Identity: 32% (40 aa)

VGTLDYSAVEIVRKDPGGYGHKVDWWSMGAILYECVFGYPPFGSD------NPRDSVKKIVKYKQYLKFPADPKVS-----------------PECIDLI
.||..| | |..| .  .||.|||.||.| |||| ..|.||| ..      ...  ...| . .    .| .  .|                 .||.|.|
CGTPWYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

KHLIC-EPEERYDFEQIKAHPWF
| ..|  |..|. .|||. ||||
KWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_8587.AA RSK-Unclassified 288-391 36 3.4e-20 59.65 In-house 178-283 (283) Show / Hide 
Range on Protein: 288-391
Range on HMM: 178-283/283
Sequence Identity: 36% (40 aa)

RAYSTVGTLDYSAVEIVRKDPGGYGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKYKQYLKFPADPKVSPECIDLIKHLICEPEERY------D
|. | .|| .| | |..|    | .  |||| .| ..||  || ||.  .|     . |   |. .||| |  .| .| |||| |    . .       |
RTNSFCGTEEYLAPEMIRR--CGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIE--KNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGD

FEQIKAHPWF
 . ||.|| |
ADDIKRHPFF
Kinase GL50803_8587.AA ROCK 288-391 35 6.2e-20 64.29 In-house 155-263 (263) Show / Hide 
Range on Protein: 288-391
Range on HMM: 155-263/263
Sequence Identity: 35% (39 aa)

RAYSTVGTLDYSAVEIVRKDP--GGYGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKYKQYLKFPADPKVSPECIDLIKHLICEPEER---YDF
|.   ||| || . |...     | ||. .||||.|  .|| ..|  ||  |       ||.  |. |||| |...| .  |||.  . . |.|   .  
RCDTAVGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGV

EQIKAHPWF
..||.|..|
DDIKQHKFF
Kinase GL50803_8587.AA MAST 293-391 34 2.9e-18 55.15 In-house 225-334 (334) Show / Hide 
Range on Protein: 293-391
Range on HMM: 225-334/334
Sequence Identity: 34% (39 aa)

VGTLDYSAVEIVRKDPGG-YGHKVDWWSMGAILYECVFGYPPFGSDNPRDSVKKIVKYKQY-LKFPAD------PKVSPECIDLIKHLICE-PEERYDFE
.||.|| | |.  .   | .|  ||||||| |.||   |.|||  |.|     .|....    ..| .       . ||| .|||. |    |..|  . 
CGTPDYIAPEVILGQ--GTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGAN

----QIKAHPWF
    ..| || |
NGADEVKQHPFF
Kinase GL50803_8587.AA S_TK_X 392-456 26 8.1e-12 46.5 SMART 1-79 (79) Show / Hide 
Range on Protein: 392-456
Range on HMM: 1-79/79
Sequence Identity: 26% (21 aa)

ANVDWNDLHS----YNPPFKPNVS----SEVDLKYFD--FVNEAKDGGPV-EALPECKEQVKWF----SPPTFGNYTYRA
...||..| .    . |||||...    |. |...||  | .|. .  |. ..| ..  | .      .|. |...||..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNE-METEIPPDPFRGFTYVF
Kinase GL50803_8587.AA TyrKc 74-391 21 3e-07 -105.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 74-391
Range on HMM: 1-280/280
Sequence Identity: 21% (73 aa)

FEKIKMLGKGAFGSVWLVREKSTQKYFAMKQLCKDEMIRRGQVEHCITEKEIMASS--VSDWIIRLYYSFQDD-------LYLYLVMEFAIGGDLMGLLI
 ...|.|| |||| |.. . |      | | | .|       .|  . | .|| .     . |.|||    ..         |..|||.. .|||   | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RVDL-FPEPVARFYMSQCCACINEIHKNNSFYRDAKPDNFLISESGHVKLSDFSLAKDFKSR--PGTMEVTTMSDEHLGTGSINPLASPTLSPGLSGTAS
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KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG----------------------------------

SLRSEATGSITA----PSMT-VPDNVGIMHNRAYSTVGTLDYSAVEIVRKDPGGYGHKVDWWSMGAILYE-CVFGYPPFGSD----NPRDSVKKIVKYKQ
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----ESKDYYRKKEHKGGKTMLP----------------IRWMAPECI--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGY

YLKFPAD------PKVSPECIDLIKHLICE-PEERYDFEQIKAHPWF
... |..      .  ..|  ...|    | ||.|  |..|  |  |
RMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_8587.AA Pkinase_Tyr 74-90 47 0.001157 13.03 Pfam 1-17 (270) Show / Hide 
Range on Protein: 74-90
Range on HMM: 1-17/270
Sequence Identity: 47% (8 aa)

FEKIKMLGKGAFGSVWL
 ...|.||.||||.|..
ITFGKKLGEGAFGEVYK
Kinase GL50803_8587.AA Pkinase_Tyr 204-221 50 0.075703 6.88 Pfam 143-160 (270) Show / Hide 
Range on Protein: 204-221
Range on HMM: 143-160/270
Sequence Identity: 50% (9 aa)

LISESGHVKLSDFSLAKD
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LVTENNVVKICDFGLARD