Gene CaMKI (Fruit Fly)

CaMKI

Species: Fruit Fly
Alias: calmodulin-dependent kinase, SFO052, camKI, CaMKI, CG1495, dCKI
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 102B7,

Classification

Group: CAMK
Family: CAMK1

Sequence

Name Sequence Type Origin Length Description Download
CaMKI.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 272 Kinase domain by global Sugen HMM Fasta, JSON
CaMKI.AA Protein Various 405 None Fasta, JSON

Protein domain

Protein domains of CaMKI.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CaMKI.AA CAMK1 31-302 57 2.2e-217 638.57 In-house 1-276 (276) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-276/276
Sequence Identity: 57% (165 aa)

YNLHGLLGTGAFSEVRLAESKDSP--GEHFAVKIID-KKALKGKE----ESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVME
|...  .|.||||||.|.. |...  |...|.|.|| ||..|.|.    |.||||| .....|            .. ||||... | ||.....|||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVS------------KIDHPNIIKFYEWYESDNHFYLVME

LVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIM--ISDFGLSKMEDSG--IMATACGTPGYVAPEVLAQ-
|||||||||||||||.||||||.|...|||.|| |||..|.|||||||||||||..|.||||.  |.||||||..|..  .| ||||||||||||||.. 
LVTGGELFDRIVEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECK

--KPYGKAVDVWSIGVISYILLCGYPPFYDEN-DANLFAQILKGDFEFDSPYWDEISES-AKHFIKNLMCVTVEKRYTCKQALGHAWI
  |||.||.|.||||||.|||||||||||||| |..||..|.|...||.||.||.||.. ||.|||....|  .|||||.|.| | ||
KDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CaMKI.AA CAMK 36-302 29 3.5e-142 461.34 In-house 1-425 (425) Show / Hide 
Range on Protein: 36-302
Range on HMM: 1-425/425
Sequence Identity: 29% (128 aa)

LLGTGAFSEVRLAESKDSPG-----------EHFAVKIIDKKALKG---------------------------KEESLENEIRVLRRFSANHFDGKCLNG
 ||.|.|..|.|.. | ..|           ...|.|||||| ||.                           .......||..... ....        
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN-------

TRLTHPNIVQLLETYED-------------------KSKVYLVM---ELVTGGEL----FDRIVEKGS---------------YTEKDASHLIRQILEAV
 .| ||||..|.|.|||                   ....|.||   |...||||    ||.|||.|.               .||..|....|||..||
-KLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAV

DYMHEQGVVHRDLKPENLLYYSPDDDS--------------KIMISDFGLSKMEDSGI-------------------------MATACGTPGYVA-PEVL
.|.|....|||||||||.|. . .|||              .| |.|||.... |.|                          | | ||||.|.| ||||
HYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL

AQ--------------KPYGKAVDVWSIGVISYILLCGYPPFYDE-------------NDANLFAQILKGDFEFDSPY------------WDEISES---
 .              ..||...|.||.||| ||.||||||||..             || .|| .|.||...|..||            ||.||..   
NGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH

-----AKHFIKNLMCVTVEKRYTCKQALGHAWI
     .|..|.....|  |||.|..|.| | |.
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CaMKI.AA RAD53 31-302 38 6.6e-128 383.25 In-house 1-305 (305) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-305/305
Sequence Identity: 38% (122 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALK-------GKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDK-SKVYLVM
| . . ||.|.|..|.||  |.  .. .|.|||||| .        .|.....||...|.               .| ||.|..... ....   .|.|.
YYMSKELGSGNFGTVKLAYEKKT-CQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILK---------------KLNHPCIIRIYDIFDTPQKYYYMVL

ELVTGGELFDRIV-EKGS---YTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDS---------------KIMISDFGLSKMEDSG-IMA
||.||||||..||  |.    ..| ..  . .|...|| | |..| .|||||||| |. ..|..                .| |.||||||  . |  | 
ELMTGGELFNKIVSNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMK

TACGTPGYVAPEVLAQK---------------PYGKAVDVWSIGVISYILLCGYPPFYDEND-----ANLFAQILK-GDFEFDSPYWDEISESAKHFIKN
| |||| ||||||.. |                |.|.||.||.|.| ||.||||||| |. .      .|| ||.. | ..|..||||.|||.||..||.
TMCGTPQYVAPEVITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKW

LMCVTVEKRYTCKQALGHAWI
. || .|||||...|| | |.
MLCVDPEKRYTIDEALNHPWM
Kinase CaMKI.AA CDPK 31-302 43 2.2e-125 386.44 In-house 1-271 (271) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-271/271
Sequence Identity: 43% (126 aa)

YNLHGLLGTGAFSEVRLAESK-DSPGEHFAVKIIDKKALKGKE--ESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVME--LV
| ... ||.|.|..||..  |  .  | .|.||| |. .| ||  ... ||| .|. .                ||||... |.|.|.  .|.|||  ..
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQL---------------DHPNIIKIYEFYQDEKNYYIVMETEYC

TGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDS----KIMISDFGLSKMEDS------GIMATACGTPGYVAPEV
|||||||.|.|||..|||.|.  .|||| || |.|....|||||||||.|. | .|||     | . |.|.||  |.        | . |||| |.||||
TGGELFDYIIEKGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEV

LAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI
| .| | . .|.||.||| ||||||||||| .||   .... || ..|. | ||.||..||  |... |.  .||... ||| | |.
LQKK-YNEKCDIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CaMKI.AA Ciliate-E2a 31-302 37 6.6e-117 345.64 In-house 1-275 (275) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-275/275
Sequence Identity: 37% (110 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGK--EESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGG
| .. ..|.|.|  |.||. |.  |..||.|...||.   |  .|...|||  .|.                 |||| .| |.|||..  |||||.. ||
YKFIKKIGKGNFGSVYLAQHKQ-TGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQL---------------DHPNIIKLYEVYEDENNYYLVMEYCEGG

ELFDRIVEKGSYTEK--DASHLIRQIL-EAVDYMHEQGVVHRDLKPENLLYY--SPDDD--SKIMISDFGLSKME--DSG-IMATACGTPGYVAPEVLAQ
||.|.|.......|.  .......|.| ... ||| ....||||||||.|.   |....  |.|.|.||||..    |..  | . ||||||||||||. 
ELYDKIKQCKRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNN

KP------YGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPY-WDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI
|       |.. .|.||.||| ||||||.|||. .. .  . |. |  . |..|  | ..| ..|...| .  .  .||.|..||| | | 
KEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase CaMKI.AA DCAMKL 31-302 39 4.90000000001e-113 353.11 In-house 1-279 (279) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-279/279
Sequence Identity: 39% (115 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKI-----------------IDKKALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYE
| .  . | | |. | ..  .    . .| ||                 |||...||||   .||.....               .. ||.|.|| | ..
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQ---------------KIKHPHIIQLYEHWD

DKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYS-PDDDSKIMISDFGLSKMEDS--GIMATACGTPGY
 . . |||||.|.|| ||| |.| . .||.||. ..... .|  |.|| ..||||.|||||| .  .|    .   |||| .  .   | . | |||| |
TETHYYLVMEYVQGGDLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDGEKSLKLCDFGLACHVNGDFGPLYTVCGTPTY

VAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDE--NDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI
||||.|. . ||  ||.|..||| ||||||.|||  .  .   || ||. |.|||..||||.|| |||  |.... |..||||| .| . | |.
VAPEILMETGYGCKVDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CaMKI.AA S_TKc 31-302 34 2.6e-104 353.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-231/231
Sequence Identity: 34% (99 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTG--G
| .. ..| |||..|...  |.  |...|.|||.        |....||..|..                 |||||.|.....| ...|.|||.. |  |
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK----------------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLG

ELFDRIVEKGS------YTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQKPYG
.|||.|...|.      ..| .| ....||..|..|.|..|..||||||||.|  .      |.|.||||..        | |||| |.|||||   .||
DLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYG

K-AVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALG-------HAWI
| ..|.||.|.| |..|||||||.  ... .| .|.              |..||.||......  |||.|. .||        | |.
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CaMKI.AA PSK 31-302 42 2.6e-104 334.3 In-house 1-258 (258) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-258/258
Sequence Identity: 42% (117 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGEL
|.   | |.| || |   | . .    .|.|....|   |. |  ||| ..||| .               ||.|.||.| .| ...||.|||. ||||.
YDIKALIGKGSFSRVVRVEHR-VTRQPYAIKMVETKCREGR-EFCENELNILRRVR---------------HPYIIQLMEVFETQDRVYMVMEMATGGEM

FDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGL---SKMEDSGIMATACGTPGYVAPEVLAQKPYGKAVDV
||||| ||..||.||    . .|... |.|  .. |||||||||||| | ..||||| ||||    |  .  .| | |||| |.|||||  ||| ..|| 
FDRIVAKGRFTERDATRVLQMVLDGMRYLHALRITHRDLKPENLLYYHPGNESKIMITDFGLAYQRKKSNDWMMKTTCGTPEYIAPEVLLRKPYTQSVDM

WSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI
| .||| |||. |  || |..   |. .||.| . .   .| ..|. || ||  |. .   .| |  ||. | |.
WAVGVIAYILMSGIMPFDDDCRTRLYRHILTGKYNYYGQPWPSVSHLAKDFIDKLLEINQGERMTASQAMKHPWV
Kinase CaMKI.AA CAMK-Unique 31-302 27 6.6e-101 333.87 In-house 1-363 (363) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-363/363
Sequence Identity: 27% (103 aa)

YNLHGLLGTGAFSEVRLAESKD-SPGEHFAVKIIDK---KALKGKE----------------ESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLE
| .| ..|.|.|..|. .  .| . |  .|.|.. |   .  |.|.                 .|..|.....               .. ||||..|..
YKMHRIIGHGNFGHVYEC--MDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWK---------------MVDHPNIIKLYD

T----YEDKS---------------KVYLVMELVTGGELFDRIVE--------------------KGSYTE--KDASHLIRQILEAVDYMHEQGVVHRDL
.    ..|.                . |.|||...||.||| |..                    .|...|   |.. .....|.|| |||.|..|||||
WNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDL

KPENLLYYSP-DD------------DSKIMISDFGLSKMEDSGIMA----TACGTPGYVAP--------------EVLAQKPYGKAV----DVWSIGVIS
|.||...... .|            ...| ..||||.. ... .|     | |||| |.||              ||... .|.  .    | ||.||| 
KLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIM

YILLCGYPPFYDENDA--------NLFAQILKGDF-EFDSPYWDE---ISESAKHFIKNLMCVTVEKRYTCKQALGHAWI
|..|||.|||. |...        ..|. |.|||. .||...|.    ||..|| |.|..| | . .| ..|..| | ||
YYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CaMKI.AA Pkinase 31-302 33 6e-99 339.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-293/293
Sequence Identity: 33% (105 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKE-ESLEN--EIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTG
| ... .| |.|..|...  |...   .|||||.|.  | .. ... .  ||....|..               |||||.|....|||...|.|||.. |
YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---------------HPNIVRLYDWFEDKDHIYMVMEYCEG

G----ELFDRIV--EKGSY--TEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYY-SPDDDSKIMISDFGLSK---MEDSGIMATACGTPGYVAPEV
|    .|||.|   ..|..  .|... . ..|||....|.|..|..||||||||.|.   .. |... |.||||.|      .. | | ||||.|.||||
GLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV

LA-QKPYGKAVDVWSIGVISYILLCGYPPFYDE------NDANLFAQILKGDFEFDSPYWDEIS-----------------ESAKHFIKNLMCVTVEKRY
.  ...||..||.||.|.| |..|||.|||...      ..  ....|......||.|.|..||                 |..|.|||.. |.  .||.
IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

TCKQALGHAWI
|..|.| | |.
TAEQILQHPWF
Kinase CaMKI.AA RSK 31-302 29 3.8e-93 315.74 In-house 1-278 (278) Show / Hide 
Range on Protein: 31-302
Range on HMM: 1-278/278
Sequence Identity: 29% (87 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKE---ESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTG
  . | .| |... .|  . .|. | ..|.|...|. .. ..   .    |...| |                 ||.||.| .......|.||.||.. |
LKVLGQGGYGKVFLCRKCTHHDT-GQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQ--------------HPFIVTLHYAFQTEGKLYLIMEYCRG

GELFDRIVEKGS---YTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDD-SKIMISDFGLSKM---EDSGIMATACGTPGYVAPEVLA---
||||... ....    .|..|.  ...|  ||...|.||..|||||||| || . . .   |...|||..|    .... . | |.|  |.|||.|.   
GELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRAN

QKP-YGKAVDVWSIGVISYILLCGYPPFYD---ENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYT-----CKQALGHAWI
|.  ..||.|.|| ||. | .| |.|||.    .| . ....|.||.| ...| |...|. ||..|. ....  .||..      .. . |.|.
QQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CaMKI.AA CAMKL 99-302 37 6.4e-83 264.44 In-house 68-297 (297) Show / Hide 
Range on Protein: 99-302
Range on HMM: 68-297/297
Sequence Identity: 37% (88 aa)

RLT---HPNIVQLLETYEDKSK------VYLVMELVTGGE--LFDRIVEK----GSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDS
.|    ||||..|.|..|....      .|||||.. |||  |||.||..    |. .|..| .. |||..||.|.|..|.||||.||||.|  . ..  
MLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-

KIMISDFGLSKM-ED-----SGIMATACGTPGYVAPEVLAQ--KPYG-KAVDVWSIGVISYILLCGYPPFYDENDA-------NLFAQILKGDFEFDSPY
.| |.|||.| | ..        . | ||.| | |||...   |||  ..||.||.||| | ..||| || |....       .|. .| .| ...  | 
NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYP--PI

WDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI
| ..| .....|. .. |  |||.|..| . | | 
WYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase CaMKI.AA CAMKL 31-86 28 2.5e-15 45.24 In-house 1-70 (297) Show / Hide 
Range on Protein: 31-86
Range on HMM: 1-70/297
Sequence Identity: 28% (20 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLEN--------------EIRVLRRFS
|..   ||.|.|..|.||. .  .||. |.|||||| .. .. .. |              ||. .....
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN
Kinase CaMKI.AA TyrKc 31-283 21 2.7e-14 8.31 SMART 1-280 (280) Show / Hide 
Range on Protein: 31-283
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

YNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRF--SANHFDGKCLNGTRLTHPNIVQLLETYEDK-------SKVYLV
  |   || ||| ||.... |    .  ||| . . |    .| . .|.|.....  .               |||||.|.    ..         ...|
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA----REDFMREARIMCKLGGH---------------HPNIVRLYGVCTQQGRNFMYIEPLMIV

MELVTGGELFDRIVEKGS-YTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSG--------IMATAC--GTPG-
||.. .| | |.. ...   . ||  .   || .  .| |.....||||   | |. ..     . |||||||.  ...           ..   |. . 
MEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

----YVAPEVLAQKPYGKAVDVWSIGVISY-ILLCGYPPFYD-----ENDANLFAQILKGDFEFDSPY--------------------WDEISES--AKH
      |||..  . .  . |||| ||  . |.  | .| ..      ... ..... .|.     |.                    |.|  |.     
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

FIKNLM
 |. ..
EIHECF
Kinase CaMKI.AA Pkinase_Tyr 98-169 31 1.2e-07 26.56 Pfam 58-137 (270) Show / Hide 
Range on Protein: 98-169
Range on HMM: 58-137/270
Sequence Identity: 31% (25 aa)

TRL-THPNIVQLLETYE-DKSK--VYLVMELVTGGELFDRIVE----KGSYTEKDASHLIRQILEAVDYMHEQGVVHRDL
. |  |||||.|.     ..    .|.|||.. .| | |   .    |.. | ||  .  .|| .. .| .... .||||
KQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase CaMKI.AA Pkinase_Tyr 31-86 23 0.029624 8.26 Pfam 1-62 (270) Show / Hide 
Range on Protein: 31-86
Range on HMM: 1-62/270
Sequence Identity: 23% (15 aa)

YNLHGLLGTGAFSEVRLAESK---DSPGEHFAVKIIDKKALKGKE---ESLENEIRVLRRF-S
  .   || ||| ||.... |   |... . |||.. |     ..   |.. .|..... . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGH