Gene CG17528 (Fruit Fly)

CG17528

Species: Fruit Fly
Alias: CAMK-like, CG17528, SFO221
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 41F2,

Classification

Group: CAMK
Family: DCAMKL

Sequence

Name Sequence Type Origin Length Description Download
CG17528.AA Protein Various 725 None Fasta, JSON
CG17528.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON
CG17528.NA RNA None 2861 None Fasta, JSON

Protein domain

Protein domains of CG17528.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DCX CG17528.AA DCX 153-244 42 1.9e-48 168.19 SMART 1-96 (96) Show / Hide 
Range on Protein: 153-244
Range on HMM: 1-96/96
Sequence Identity: 42% (41 aa)

PTRKALRIKFYRNGDRFYPGITIPVSNER-YRSFERLFEDLTR-LLEENVKIPGAVRTIYNLCG-KKITSLDELEDG-QSYVCSCNNENFKKVEYN
...|..||.||||||.|..|... ..... ..||..|..|.|. .|......|..||.||...| ...|||||.||| ..|||.|.||.||.|.|.
HHWKPKRICFYRNGDPFFKGVRLVINRKWQFKSFDHLLQDVTQTKLHVKMDCPHGVRHIYTTDGRHRVTSLDEFEDGDDFYVCCCTNEKFKPVDYD
DCX CG17528.AA DCX 175-239 44 8.5e-31 111.04 Pfam 1-68 (68) Show / Hide 
Range on Protein: 175-239
Range on HMM: 1-68/68
Sequence Identity: 44% (30 aa)

IPVSNERYRSFERLFEDLTRLLEENVKIPGA-VRTIYNLCG-KKITSLDE-LEDGQSYVCSCNNENFK
..|...|...|. | .|.|..|...|. | . ||.|| ..| ...||||| |.||..|||.| || ||
MVVNRRRFKTFDALLDDITESLHDKVQLPFGAVRKIYTPDGGHRVTSLDEFLQDGGCYVCCCGNERFK
DCX CG17528.AA DCX 285-373 26 4.1e-37 130.55 SMART 1-96 (96) Show / Hide 
Range on Protein: 285-373
Range on HMM: 1-96/96
Sequence Identity: 26% (25 aa)

TVVHPRIVTLIRSGTKPRRIMRLLLNKRN-SPSFDHVLTAITQ---VVRLDTG-YVRKVFTLSG-IPVVRLSDFFGSDDVFFAYGTE-RINTAEDF
. ..|......|.| ......||..|... ..||||.|...||   .|..|.. .||...|..| ..| .|..|...||......|. ........
HHWKPKRICFYRNGDPFFKGVRLVINRKWQFKSFDHLLQDVTQTKLHVKMDCPHGVRHIYTTDGRHRVTSLDEFEDGDDFYVCCCTNEKFKPVDYD
DCX CG17528.AA DCX 307-368 30 2.5e-20 74.37 Pfam 1-68 (68) Show / Hide 
Range on Protein: 307-368
Range on HMM: 1-68/68
Sequence Identity: 30% (21 aa)

LLLNKRNSPSFDHVLTAITQ----VVRLDTGYVRKVFTLSG-IPVVRLSDFFGSDDVFFAY-GTERIN
...|.|....||..|. ||.    .| |..|.|||..|..|  .|  | .|. ........ | ||..
MVVNRRRFKTFDALLDDITESLHDKVQLPFGAVRKIYTPDGGHRVTSLDEFLQDGGCYVCCCGNERFK
Kinase CG17528.AA DCAMKL 454-712 59 7.4e-206 647.13 In-house 1-279 (279) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-279/279
Sequence Identity: 59% (166 aa)

YSLGRIIGDGNFAIVFKIKHRQTG-HSYALKI-----------------IDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGG
|..||||||||||.|....||.|| |.||.||                 |||.|||||||.||.||..|.|..|||||.|. ..|..|..|||.|||.||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

DLFDAITQVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVND---LLYAVCGTPTYVAPEILLEVGYGLK
|||||||..|.|.|....||...|..|..|||.|.|||||||||||||. .|.| ...|||.||||||.||.   .||.||||||||||||| |.|||.|
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSLKLCDFGLACHVNGDFGPLYTVCGTPTYVAPEILMETGYGCK

IDVWAAGIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWT
.|.||||.||||||||||||..|||.||.|||.|..|..|||.|||..|.|...|||..|||.||..|.|.|.|..|.|.
VDIWAAGVILYILLCGFPPFRSPDNDQEELFDQIMQGKFEFPMPYWDNISDSAKDLISHMLQVDPEKRYTAEQIMQHPWV
Kinase CG17528.AA CAMK 459-712 26 1e-115 374.54 In-house 1-425 (425) Show / Hide 
Range on Protein: 459-712
Range on HMM: 1-425/425
Sequence Identity: 26% (113 aa)

IIGDGNFAIVFKIKHRQTG------------HSYALKIIDKNKCKG---------------------------KEHYIDAEVRVMKK-------LNHPHI
..| |.|..|.. .|..|.            . .| |||||.| |.                           ... .  |...|||       |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLILSVDQ-------------------NTNMYLVL---EYVSGG----DLFDAITQV---------------TRFSENQSRIMIRHLGAAMTYLHSMGI
|.|.   .                    ...||.|.   ||.|||    |||| |..                 ||.| . | ..| .  |. |.||..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDIKPENLLVKLDEHGNV------------LELKLADFGLACEVND--------------------------LLYAVCGTPTYVA-PEILL-------
||||.||||.|.  .. ..               .|..|||.|.....                          ... .|||| |.| ||.|.       
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------EVGYGLKIDVWAAGIILYILLCGFPPFVAPDNQQEP-----------LFDAIISGIYEFPDPY------------WSDIGDG--------VRD
       . .|| |.|.|..|.||||.|||.||| ........           ||  |..| |.||.||            |.|| |         ..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LIANMLQADPDVRFTSEDILDHSWT
|| .||| ||. |.| |..|.| | 
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CG17528.AA CAMK1 454-712 39 9.20000000001e-113 329.13 In-house 1-276 (276) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-276/276
Sequence Identity: 39% (110 aa)

YSLGRIIGDGNFAIVFKIKHRQT---GHSYALKIID-KNKCKGKE----HYIDAEVRVMKK---LNHPHIISLILSVDQNTNMYLVLEYVSGGDLFDAIT
| .| .|| | |..|.. .|..|   |. ||.|.|| |   |.|.     ... |. .|||   ..||.||...   . ..  |||.|.|.||.||| | 
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

QVTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELK--LADFGLACEVN-D--LLYAVCGTPTYVAPEILLE---VGYGLKID
. . ..|.. |  .. .  |  |.||.||||||.||||||  .    .  ..|  .|||||.  .. |  |.. .|||| |||||.|      .|. ..|
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLL--YYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACD

VWAAGIILYILLCGFPPFVAPD-NQQEPLFDAIISGIYEFPDPYWSDIGDG-VRDLIANMLQADPDVRFTSEDILDHSWT
.| .|.|.||||||.||| . . ...  ||. |... |||| |.| .| |. . |.| .||  ||  |.| |..|.| | 
MWSIGVITYILLCGYPPFYDENVDNE--LFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI
Kinase CG17528.AA RAD53 454-712 34 1.7e-105 315.22 In-house 1-305 (305) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-305/305
Sequence Identity: 34% (106 aa)

YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDK-------NKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQ-NTNMYLVLEYVSGGDLFDAIT-QV
|......| |||..| . . . |.  .| |||||       ..  .|.  .  ||...|||||| ||... ..|   .. |.|||...||.||. |  . 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILKKLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIVSNK

TR---FSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGN-------------VLELKLADFGLACEVNDL--LYAVCGTPTYVAPEILLE
..   |.|....   . .  |  |||..||.|||.|||| | . .....              . .|..||||.  | .   .   ||||.|||||... 
RCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEVITS

---------------VGYGLKIDVWAAGIILYILLCGFPPFVAPDNQ---QEPLFDAIIS-GIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDIL
               |||. | |.| .| ||||.|||.|||  .. |     .||. |.. | |.|| |||..| . ..||| .||. ||. |.| ...|
KGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPFSDDYTQEMHCMQLFEQIKNQGKYHFPHPYWDRISEEAKDLIKWMLCVDPEKRYTIDEAL

DHSWT
 |.| 
NHPWM
Kinase CG17528.AA S_TKc 454-712 35 7.3e-94 319.06 SMART 1-231 (231) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-231/231
Sequence Identity: 35% (97 aa)

YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSG--GDLFDAITQVTR-----
| ..|.|| | |. |.| .|. ||. .|.|||.          |  |....|| .||.|. |. . .  ...|.|.||..|  ||||| | .  |     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDLLYAVCGTPTYVAPEILLEVGYGL-KIDVWAAGIILYI
 |.| . | ... .  |. |.||.||.|||.||||.|.         ..|..|||||...    . .|||| |.|||.|   |||  |.|.|. |.|||.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILD-------HSWT
.||| |||     |.. .|. |                . ..|.| ..|| ||. | |  ..|        | | 
MLCGYPPFP----QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG17528.AA CAMKL 454-712 35 2.2e-92 295.14 In-house 1-297 (297) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-297/297
Sequence Identity: 35% (108 aa)

YSLGRIIGDGNFAIVFKIKH-RQTGHSYALKIIDKNKCKGKEHYIDA--------------EVRVMKKLN---HPHIISLILSVDQNTN------MYLVL
| .|. .| |.|. |   .| | ||. .| |||||.|.. ...  .               |.. ||.||   ||.||.|   ..  ..      .|||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYVSGGD--LFDAITQV----TRFSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACE---V----NDLLYAVCGTP
||.|||.  ||| | .      |..|.. | . | . .|. |.||.|||||||||||.|  |||.||   .|..|||.. .   .    ...|   ||.|
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENIL--LDENGNN-NIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

TYVAPEILLE--V-GYGLKIDVWAAGIILYILLCGFPPFVAPDN------QQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDIL
 | ||||..      .| |.|.|..|.||| ..||  || ....       .  |.  |..| |..| .|  ..   .||||  ||| .|. |.| ..|.
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWY--HVS-DCRDLIRKMLQVNPEKRPTIHQIM

DHSWT
 | | 
NHPWM
Kinase CG17528.AA Pkinase 454-712 34 1.8e-89 308.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-293/293
Sequence Identity: 34% (103 aa)

YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDA---EVRVMKKLNHPHIISLILSVDQNTNMYLVLEYVSGG----DLFDAIT--QV
| .||.|| |.|. |.| .|. ||. .|.|||.| . | .......   |...||.||||.|. |. ..  ....|.|.||. ||    |||| |.  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TRF--SENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLAC---EVNDLLYAVCGTPTYVAPEILL-EVGYGLKIDVWAA
..|  ||.. . ... .  .. |.|||||.|||.||||.|.. ..  .   .|..|||||.   . |. .. .|||| |.|||...   .|| |.|.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIILYILLCGFPPFVAP----DNQQEPLFDAIISGIYEFPDPYWSDIG-----------------DGVRDLIANMLQADPDVRFTSEDILDHSWT
|.|||..||| |||       .. |  ... | .....|. |.|..|                  .  .|.| ..|. ||  | | |.|| | | 
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CG17528.AA CAMK-Unique 454-712 26 1.6e-88 292.33 In-house 1-363 (363) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-363/363
Sequence Identity: 26% (96 aa)

YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYI-------------------DAEVRVMKKLNHPHIISLILS-----VDQNT------
| ..||||.||| .|.. . | ||  .| |.. | . . |  ..                   . |....|...||.|| |        .| .       
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------NMYLVLEYVSGGDLFDAITQ--------------------VTRFSE--NQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHG----
        .||.|.||. ||||||.| .                     ..|||  ....  .. |  |  |.|| .|||||.|.||..|.  .      
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH

-------NVLELKLADFGLACEVN----D-LLYAVCGTPTYVAP--------------EILLEVGYGLKI----DVWAAGIILYILLCGFPPFVAPDNQQ
       . . .||.||||.|..|    . .. ..|||| |.||              |.. ...|. .     | |. | |.|..||| ||| ....  
RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDR

------EPLFDAIISGIY-EFPDPYWSD---IGDGVRDLIANMLQADPDVRFTSEDILDHSWT
        .|..| .| | .|. ..|..   |...  |.. . .. |||.| ... .|.|.| 
DYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase CG17528.AA CDPK 454-712 36 2.8e-88 270.89 In-house 1-271 (271) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-271/271
Sequence Identity: 36% (99 aa)

YSLGRIIGDGNFAIVFKIKHR-QTGHSY-ALKIIDKNKCKGKEH-YI-DAEVRVMKKLNHPHIISLILSVDQNTNMYLVLE--YVSGGDLFDAITQVTRF
| .....| |.|  |.|.||. .|. .  | ||| |...| ||  ..   |. ..|.| ||.|| .      . | |.|.|  |..||.||| |..  .|
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

SENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGN--VLELKLADFGLACEVN-------DLLYAVCGTPTYVAPEILLEVGYGLKIDVWAA
.| ...  .| .  |  | || .|||||.||||.| . .. ..    ..|. |.|.... .       . ..  ||||.|.|||.|    |  | |.| .
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKK-YNEKCDIWSC

GIILYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWT
|.|||||||| ||| .   |.   ....  | |.| .| |..| |  .||| .||. ||. |......|.| | 
GVILYILLCGYPPFYGKNDQE--IMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF
Kinase CG17528.AA MARK 454-712 36 2.8e-80 262.14 In-house 1-262 (262) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-262/262
Sequence Identity: 36% (99 aa)

YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKG-KE-HYIDAEVRVMKKLNHPHIISLILSVD--QNTN-MYLVLEYVSGGDLFDAITQV--TR
| ... || |..| | .  |. ||  .|.||..|.|    ..   .  |...||||.||.||.|   ..   ...  ||..||.|||.|.| | ..   |
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHG--NVLELKLADFGLACEV--NDLLYAVCGTPTYVAPEILLEVGYG-LKIDVWAAGII
 .|.  | . | .  |. |.||..||||||||||.|  .||.|  |.   |..|||.. ..  . .|   |||| | ||||.|   |   |.|.|. |..
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENIL--IDENGNHNI---KIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVV

LYILLCGFPPFVAPDNQQEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFTSEDILDHSWT
||...||  || . .. .. |.  | .| |..|.     . .. |.||  .|...|. | | |.|. |.| 
LYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase CG17528.AA RSK 456-712 29 5.7e-73 248.74 In-house 1-278 (278) Show / Hide 
Range on Protein: 456-712
Range on HMM: 1-278/278
Sequence Identity: 29% (82 aa)

LGRI--IGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEH---YIDAEVRVMKKLN-HPHIISLILSVDQNTNMYLVLEYVSGGDLFDAITQVTR---
|     .| | . .. |. |..||. || |...|.| . ..    .  .|.....  . || |..|  . . ..  ||..||..||.||. . .  .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACE-VND---LLYAVCGTPTYVAPEILL----EVGYGLKIDVWAA
|||.  .. .. .  |. .||. ||.|||.|||| |   ..  |  ..|| |||.... ..|   ...  |.|  |.|||.|     ..|..   |.|  
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES--NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSL

GIILYILLCGFPPFVAPDNQ--QEPLFDAIISGIYEFPDPYWSDIGDGVRDLIANMLQADPDVRFT-----SEDILDHSWT
|...| .| |.||| . .|.  .. ... | .| . .. | |. . .  .|||  ||. ||  | .      |.|..|.| 
GVLMYEMLTGCPPFQG-PNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CG17528.AA Ciliate-E2 454-712 27 7.7e-73 248.3 In-house 1-365 (365) Show / Hide 
Range on Protein: 454-712
Range on HMM: 1-365/365
Sequence Identity: 27% (108 aa)

YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNK---------CKGKE-----------HYIDAEVRVMK----------------KLNHPHIISLIL
| . ..|| |||..|.| |...... .|.|||| .|         .|.|.            .|  | ..|.                .||||.|| .. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SVD--QNTNMYLVLEYVSGGDLFDAIT------------QVTRFSENQSR-IMIRHL-GA-------------AMTYLHSMG-IVHRDIKPENLLVKLDE
.    ...|.|||.||..|||||| |             .  .|.|.. . ||   | |              |. |||| . |.||||||||.|.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

HGNVLELKLADFGLACEVN----------------------------------DLLYAVCGTPTYVAPEILLEVG---------YGLKIDVWAAGIILYI
      .|..||||. ...                                  .. . .|||| |.|||||   .         |. |.|.|..|.|||.
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

LLCGFPPFVAPDNQQEPLFDAIISGIYEFPDP--------------YWSDIGDGVRDLIAN----MLQADPDVRFT-SEDILDHSWT
.|.| |||          .. |. . ..|| |               | .. . . ||| .    ||| ||. |.|  |.||.| | 
MLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CG17528.AA TyrKc 454-710 22 6.7e-15 18.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 454-710
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

YSLGRIIGDGNFAIVFKIKHRQTGHSYALKIIDKNKCKGKEHYIDAEVRVMKKL--NHPHIISLILSVDQN-------TNMYLVLEYVSGGDLFDAITQV
 .||...| |.| .|.| . .      | | . ...    .  .  | |.|.||  .||.|. |.  . |          ...|.||...||| | .   
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

TR-FSENQSRIMIRHLGAAMTYLHSMGIVHRDIKPENLLVKLDEHGNVLELKLADFGLACEVNDL--------LYAV----CGTP----TYVAPEILLEV
 . ..  .   .     . | ||||....|||.   | ||. .        | .||||. .. |          | .    .|         ||| . . 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GYGLKIDVWAAGIILY-ILLCGFPPFVA-----PDNQQEPLFDAIISG-IYEFPDPYWSD-----IGDGVRDLIANMLQADPDVRFTSEDILDHS
 .  | |||. |. .. |.  | .|         .||.  ..  . .|   . |. .          | . ...    ..||. | | ..| .  
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQE--VIEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CG17528.AA Pkinase_Tyr 454-576 26 2e-11 39.35 Pfam 1-137 (270) Show / Hide 
Range on Protein: 454-576
Range on HMM: 1-137/270
Sequence Identity: 26% (36 aa)

YSLGRIIGDGNFAIVFKIKHR----QTGHSYALKIIDKNKCKGKE---HYIDAEVRVMKKL-NHPHIISLI-LSVDQNTN--MYLVLEYVSGGDLFDAIT
 ..|. .| |.|  |.| . .    .|.   | |.. |...  ..       .|...||.| .||.|..|.   .||     .|.|.||. .||| |   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----VTRFSENQSRIMIRHLGAAMTYLHSMGIVHRDI
.      ...  .   | .   ..| ||.|....|||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL