Gene Lk6 (Fruit Fly)

Lk6

Species: Fruit Fly
Alias: CG6929, SFO043, CG17342, LK6, Lk6, MNK/LK6, MESR8
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 86F6,

Classification

Group: CAMK
Family: MAPKAPK
Subfamily: MNK

Sequence

Name Sequence Type Origin Length Description Download
Lk6.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 287 Kinase domain by global Sugen HMM Fasta, JSON
Lk6.AA Protein Various 1142 None Fasta, JSON

Protein domain

Protein domains of Lk6.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Lk6.AA MNK 118-403 72 6.5e-232 776.74 In-house 1-292 (292) Show / Hide 
Range on Protein: 118-403
Range on HMM: 1-292/292
Sequence Identity: 72% (213 aa)

KLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKI-PGHARARVFREVETFHHCQGHLGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHICFSEHEA
|||.|.|||||||||||||||....|||||.|||. |||.|.|||||||||.||||| .||||||.||||..|||||||..|||||..||....|.||||
KLTDEHLGEGAYASVQTCVNIQSGKEYAVKIIDKQGPGHSRKRVFREVETFYHCQGHRNILQLIEWFEDDDRFYLVFEKMRGGPLLQHIQQRKHFTEHEA

SQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSG---IKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVG-EAHYYDKRCD
||.||.|||.|||.|.|||||||||||||||......||.||||||||||   |....|.|.|..||.||||.||||||||||||.||. ||||||||||
SQVIKDIASALDFMHNKGIAHRDLKPENILCEHPNHVCPVKICDFDLGSGRPPIHLNHDCSQPITTPELLTPCGSAEFMAPEVVDAFVYDEAHYYDKRCD

LWSLGVIAYILLCGYPPFSGNCG-EDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWI
|||||||.||.|||||||.|.|| |||||.|||.||.||..||..|||||..|||.|||..|.|||||||||||..|..||||..||||||.
LWSLGVILYIMLCGYPPFVGHCGDEDCGWDRGEACRDCQNMLFHCIQEGHYEFPEKEWHHISEEAKDLISNLLVRDAKQRLSAAQVLNHPWV
Kinase Lk6.AA MAPKAPK 118-403 55 5.3e-216 675.89 In-house 1-292 (292) Show / Hide 
Range on Protein: 118-403
Range on HMM: 1-292/292
Sequence Identity: 55% (162 aa)

KLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKIPGHARARVFREVETFHHCQGHLGILQLIEFFED----DEKFYLVFEKINGGPLLSRIQE--HICF
||..|.||||.|..|||||...|. |||||.... |||.|....||||...|||||  |.|.|..||.    |..||||.|...||.|...||.  |..|
KLWKEVLGEGIYGKVQTCVHKRTGQEYAVKILEDQPGHSRQKARREVELHWHCQGHPNIVQIIDWFENMYQFDKCFYLVMECMEGGELFQHIQQRGHKHF

SEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDKRC
.|.|||||.|.|.|..||||...|||||||||||||..|.. ||.|.|||.....|....|...|..||.|.||......||||||. |. |||.|||.|
TEREASQIMKDICSAVDFLHSMNIAHRDLKPENILCTDTNHNCPVKLCDFGFAKEIHLNHDCTTPITTPELMTPCYTPYYMAPEVVGAFK-EAHTYDKSC

DLWSLGVIAYILLCGYPPFSGNCG-EDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWI
|.|||||| ||.|||||||..||| |||.|.|||.||.||...|..||||...||..||...|.||||||..||......||..|.|.|||||
DMWSLGVIMYIMLCGYPPFYSNCGDEDCSWDRGEACRDCQNMMFHRIQEGQYEFPDEEWSHISEEAKDLIRKLLRRDPTQRLTIEQVMNHPWI
Kinase Lk6.AA CAMK 123-403 26 1.2e-109 354.64 In-house 1-425 (425) Show / Hide 
Range on Protein: 123-403
Range on HMM: 1-425/425
Sequence Identity: 26% (114 aa)

ILGEGAYASVQTCVNIYTD------------LEYAVKVIDKI----------------------------PGHARARVFREVETFHHCQG------HLGI
.||.|... |  |... |              ..|.|.|||                              .. |..|.||.|   ..||      |  |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LQLIEFFED-------------------DEKFYLVF---EKINGG----PLLSRIQEH---------------ICFSEHEASQIIKEIASGLDFLHKKGI
..|.|..||                   |...|.|.   | . ||     |...|.||                .|.|.||..... |.|.....|...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

AHRDLKPENILCVKTDSL--------------CPIKICDFDLGSGIKFTTD---------------ISSPAATPQLLTPVGSAEFMA-PEVVDLFV----
.||||||||||... ..               ..|||.|| .   ..   .               ...|. .. . |..|. |.|| |||.        
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-----GEAHYYDKRCDLWSLGVIAYILLCGYPPFSGNCG-EDCGWNRGENCR--TCQELLFESIQEGHFSFPEAE------------WHDVSDE------
     .|  ||.. || ||.||| ||.||||||| | |. |.|. .  |  .  .... ||| |..| ..||. .            |.|.|||      
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D--E--WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

--AKDLISNLLVKKASNRLSAEAVLNHPWI
  .||||...|..  ..|...| .|||||.
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase Lk6.AA CAMK1 117-403 35 1.7e-95 278.1 In-house 1-276 (276) Show / Hide 
Range on Protein: 117-403
Range on HMM: 1-276/276
Sequence Identity: 35% (106 aa)

YKLTGEILGEGAYASVQTCVNIYT---DLEYAVKVIDK---IPGHAR---ARVFREVETFHHCQ--GHLGILQLIEFFEDDEKFYLVFEKINGGPLLSRI
|.. |...|.|| . |  |... |   . .||.|.|||   . .. .   ... .|.|  . .    |  | ...|..|.|..|||| | ..|| |. ||
YEF-GKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRI

QEHICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIK--ICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGE
 |  ...| .|. |.|.|.| . ..|.|||.||||||||.|..  |   .||  |.|| |   ..   .         . |..|. ...||||.      
VEKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDSKIKRSIADFGLSKIFDHDEN--------LMKTACGTPGYVAPEVLECKK--

AHYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDE-AKDLISNLLVKKASNRLSAEAVLNHPW
.  ||| ||.|| ||| |||||||||| .. .              .. ||| | .. . ||. .|...||. |||.|...|..  ..|...| .|||||
DKPYDKACDMWSIGVITYILLCGYPPFYDENV--------------DNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPW

I
|
I
Kinase Lk6.AA S_TKc 118-403 28 1.4e-92 314.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 118-403
Range on HMM: 1-231/231
Sequence Identity: 28% (87 aa)

KLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKIPGHARARVFREVETFHHCQGHLGILQLIEFFEDDEKFYLVFEKING--GPLLSRIQEHIC-----
   ....|.||...|  |... |. ..|.|.|.        .. ||..  ..  .|  | .|...|.| ...|.|.| ..|  | |...|... .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDK
 |.| .|  ....|...|...|..|| ||||||||||. .      |||||| |   .                | .|. ..|||||.         |.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------------TTFCGTPWYMAPEVL--------GYGK

-RCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLN-------HP
 .|| ||.|.| |..|||||||.                  ....|. |               |.||||.|...|.|  ..|..|  .|.       ||
CKCDWWSCGCILYEMLCGYPPFP-----------------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

WI
|.
WF
Kinase Lk6.AA RSK 120-403 32 3.6e-74 252.7 In-house 1-278 (278) Show / Hide 
Range on Protein: 120-403
Range on HMM: 1-278/278
Sequence Identity: 32% (96 aa)

TGEI--LGEGAYASVQTCVNIYTDLEYAVKVIDK--IPGHAR--ARVFREVETFHHCQGHLGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQ--EHI-C
  .   .| |..  .. |..  |. .||.||..|  |  ...  .....|..   .||.|  | .| . |....|.||. | ..|| |. ..|  .|  |
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSL-CPIKICDFDLGSGIKFTTDISSPAA-TPQLLTPVGSAEFMAPEVVDLFVGEAHYYD
|||.||.... ||.. ...||..|| ||||||||||    .     ||..||..            ..  . .. |.....|.||||..         .|
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES-NEGHIKLTDFGFCKQF--------RCDHNQWTMTFCYTIEYMAPEMLKRAN-QQGGHD

KRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLS-----AEAVLNHPWI
| ||.|||||. | .| |.||| |  ..|            .. ... ||.|.||..  .|. .|.||||||. .| .  ..||.     || ...|||.
KACDWWSLGVLMYEMLTGCPPFQG--PND----------NNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase Lk6.AA Pkinase 118-403 30 1.1e-73 255.93 Pfam 1-293 (293) Show / Hide 
Range on Protein: 118-403
Range on HMM: 1-293/293
Sequence Identity: 30% (95 aa)

KLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKIPGHA--RARVFR--EVETFHHCQGHLGILQLIEFFEDDEKFYLVFEKINGG----PLLSRIQ--E
  .|...|.|....|  |... |  ..|||.|.|   .   . . .|  |..  ... .|  |..|...|||. . |.|.|  .||     | ..|.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HICF--SEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLC-PIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEA
| ||  ||.|.  ....|..||...|..|| ||||||||||..... .. ..||||| |   ..           . . |..|. ..|||||    . ..
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------Y-NNS-MTTFCGTPWYMAPEV----IRGG

HYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVS-----------------DEAKDLISNLLVKK
 ||....| ||.|.| |..|||.|||.| |  . . .       .|  ... | .. ..|.. .|...|                 .|.||.|...| |.
QYYGPKVDMWSCGCILYEMLCGRPPFPGHC-WHDN-H-------DQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD

ASNRLSAEAVLNHPWI
 . |..|| .|.|||.
PKKRPTAEQILQHPWF
Kinase Lk6.AA Ciliate-E2 117-403 23 5.7e-69 235.45 In-house 1-365 (365) Show / Hide 
Range on Protein: 117-403
Range on HMM: 1-365/365
Sequence Identity: 23% (96 aa)

YKLTGEILGEGAYASVQTCVNIYTD-----------------------LEYAVKVIDKIPGHARAR---VFREVETFHHCQG--------------HLGI
||.  ...|.|...||  | .. ..                        .||.|.. |    .  .   ..||..    | .              |  |
YKF-IKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREIN----C-FYKKINEKNILEQLNHPNI

LQLIEFFE--DDEKFYLVFEKINGGPLLSRIQEHI-----------CFSEHEASQIIKEIAS---------------GLDFLHKKG-IAHRDLKPENILC
....|.|.  ||...|||.| ..|| |...|...            .|.| |...|.|.|..               .| .||.|. | |||.|||||| 
IKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF

VKTDSLCPIKICDFDL----------------------GSGIKFTTDISSPAATPQLLTPV-----------GSAEFMAPEVVD-LFVG---EAHYYDKR
        |||.|| |                      .. .. |. ...                      |....||||..     .   . ..||. 
--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD----------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK

CDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAE--------------WHDVSDEAKDLISN----LLVKKASNRL
||.|||||| |..|.|.|||                       .. |... ..||..|              |...|.|.||||..    .|.|. ..|.
CDIWSLGVILYEMLFGKPPF-----------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRI

S-AEAVLNHPWI
. .| .|||||.
TGWEQILNHPWF
Kinase Lk6.AA CAMKL 117-403 28 3e-64 203.88 In-house 1-297 (297) Show / Hide 
Range on Protein: 117-403
Range on HMM: 1-297/297
Sequence Identity: 28% (92 aa)

YKLTGEILGEGAYASVQTCVN-IYTDLEYAVKVID--KIP--GHARAR-----------VFREVETFHHCQ--GHLGILQLIEFFEDDEK------FYLV
|..    ||.|... |. ... ..|  ..|.|.||  ||    .....           ..||..   . .  .|  | .| | .|..|.      .|||
YRIGK-TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

FEKINGGP--LLSRIQEHIC----FSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIK---FTTDISSPAATPQLL
 | . ||   |. .|..| .    ..|||| .. . | |.....|..||.|||.||||||  . ..   |||.|| ..  ..   |...         | 
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN-NIKIIDFGFSNMYRPCIFGPGQ-------KLK

TPVGSAEFMAPEVVDLFVG-EAHYYDKRCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISN
|  || ..||||.   | | . .|. .  | ||.||| | ..||| || . . .        .  ... .|.. | .| . .|   | .|| ...|||. 
TFCGSPPYMAPEI---FQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN-K------QGKDNI-YLYWKIMCG-YYPP--IWYHVS-DCRDLIRK

LLVKKASNRLSAEAVLNHPWI
.|... . | ... ..|||| 
MLQVNPEKRPTIHQIMNHPWM
Kinase Lk6.AA CAMK-Unique 120-403 24 1.7e-63 208.42 In-house 3-363 (363) Show / Hide 
Range on Protein: 120-403
Range on HMM: 3-363/363
Sequence Identity: 24% (92 aa)

TGEILGEGAYASVQTCVNIYTDLEYAVKVIDK-IPGHARARV------------------FREVETFHHCQGHLGILQLIEF----FEDDE---------
...|.|.|..  |  | .. |  ..|.|.. |  .|  .  .                  ... .     ..|  |..| ..    |.|..         
MHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLIIK

------KFYLVFEKINGGPLLSRIQE--------------------HICFSE--HEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKT--D------
      ..|.| | ..|| |.. ||.                     . |||   ....|. ...| . ..|...| |||||.|||.  .   |      
TPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRD

-----SLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDL---------FVGEAHYYDKRC----DLWSLGVIAYILLCGYPPFSGN
     |   ||.|||.|       .....  . . . | .|. ..||||.|            |.... ||  |    |.||||||.|..|||.||| ..
FPYDWSNWHIKLCDFGL------CCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCE

CGEDCGWNRGENCRTCQELLFESIQEGHF-SFPEAEWHD---VSDEAKDLISNLLVKKASNRLSAEAVLNHPWI
| ..   |           .||.|  | . .|..  ||.   .|.||||.. .... . . |.||.  | |.||
CEDRDYEN-------HDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI
Kinase Lk6.AA MSK 119-403 32 1.7e-62 210.03 In-house 1-277 (277) Show / Hide 
Range on Protein: 119-403
Range on HMM: 1-277/277
Sequence Identity: 32% (95 aa)

LTGE-ILGEGAYASVQTCVNIYTDLEYAVKVID--------KIPGHARARVFREVETFHHCQGHLGILQLIEFFEDDEKFYLVFEKINGGPLLSRIQEHI
|     .|.|..  .  ||.  |...||.|..         | . |..    .|. .  .||.|  | .| . | |. ..||| | .||| |. .|    
LKVLGTGGYGKFFICRKCVHHDTGKLYAMKILSKATVVQKRKTAEHTQ----TERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKRE

CFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAHYYDK
 |.|.|...|. |. . .|..|.||| ||||||||||    ..  ..|. ||  |.   |..| . .. .     | .. ..||||...    .   ||.
HFDESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDF--GFARLFPQDEEWRMKS-----PCFTLHYMAPEMLRRGYAQDGGYDE

RCDLWSLGVIAYILLCGYPPFSGNCGEDCGWNRGEN-CRTCQELLFESIQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWI
 ||.|||||| | .| |  ||  |        ...    . .  .   |..| ||||  .|  .| .|||||. || |. . ||...  . | |.
ACDWWSLGVILYTMLTGQVPFQQN-------EDDRQHSCNSHHEIMKRICKGEFSFPGMAWQNMSPDAKDLIQWLLTKDPKKRLGMNDLRAHEWK
Kinase Lk6.AA MAPKAPK 118-330 37 4.6e-52 173.55 In-house 1-206 (268) Show / Hide 
Range on Protein: 118-330
Range on HMM: 1-206/268
Sequence Identity: 37% (85 aa)

KLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKIPGHARARVFREVETFHHCQGHLGILQLIEFFEDDEKF----------YLVFEKINGGPLLSRIQE
... ..|| |    |  |..  |.  .| ||    |   .||  ||||    | ||  | | |. .|   .|            | | ..|| |..||||
QIWKQVLGIGINGKVMQCYHKRTQQKFALKVLRDSP---KAR--REVELHWMCSGHPHIVQIIDVYENMYQFPHEPSPRKCLLIVMECMEGGELFHRIQE

H--ICFSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDFDLGSGIKFTTDISSPAATPQLLTPVGSAEFMAPEVVDLFVGEAH
.  . | | ||.||.|.|.. ....|.  ||||||||||.|.. | . |..| .||      . .... .|  ||    |    | . ||          
RGDQHFTEREAAQIMKQICQAVQHCHSMNIAHRDLKPENLLYKDTQPNCVLKLTDFGFAKETTRHNTLMTPCYTPYYVAP----EVLGPEK---------

YYDKRCDLWSLGVIAYILLCGYPPF
 ||| ||.|||||| ||.|||||||
-YDKSCDMWSLGVIMYIMLCGYPPF
Kinase Lk6.AA MAPKAPK 357-403 48 2.3e-17 54.94 In-house 222-268 (268) Show / Hide 
Range on Protein: 357-403
Range on HMM: 222-268/268
Sequence Identity: 48% (23 aa)

IQEGHFSFPEAEWHDVSDEAKDLISNLLVKKASNRLSAEAVLNHPWI
|. | ..||. || .||..||||| .||  . . ||. | ..|||||
IMNGQYEFPHPEWSCVSEDAKDLIRKLLRTDPTERLTIEEFMNHPWI
Kinase Lk6.AA TyrKc 118-403 18 5e-10 -60.51 SMART 1-280 (280) Show / Hide 
Range on Protein: 118-403
Range on HMM: 1-280/280
Sequence Identity: 18% (58 aa)

KLTGEILGEGAYASVQTCVNIYTDLEYAVKVIDKIPGHARARVFREVETFHHC-QGHLGILQLIEFFEDD-------EKFYLVFEKINGGPLLSRIQEHI
   |..|||||.  |  .. .   .. |||.. .     |.   || .  ..    |  |..|.    ..       |  ..|.|   .| |......| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

C-FSEHEASQIIKEIASGLDFLHKKGIAHRDLKPENILCVKTDSLCPIKICDF----DLGSG-IKFTTDISSPAATPQLLTPVG--SAEF------MAPE
  ..  .  ..   ||.| ..||.|.. ||||   |.|  .      .||.||    |....  .         .  .  .. .  .. .      ||||
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQG--------ESKDYYRKKEHKGGKTMLPIRWMAPE

VVDLFVGEAHYYDKRCDLWSLGVIAY-ILLCGYPPFSG---NCGEDCGWNRGENCRTCQELLFESIQEGHFSFPEAE-----WHDVSDEAKDLISNLLVK
.        . .    | || ||  . |.  | .| .|   .   .. . .          ..| ...|.   . ..         .||  ....     
CI-----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQE----------VIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHE

KASNRLSAEAVLNHPWI
....| . ...  |  .
DPEDRPTFSEI--HECF
Kinase Lk6.AA Pkinase_Tyr 117-240 25 4e-06 21.34 Pfam 1-137 (270) Show / Hide 
Range on Protein: 117-240
Range on HMM: 1-137/270
Sequence Identity: 25% (35 aa)

YKLTGEILGEGAYASVQTCVNI----YTDLEYAVKVIDKIPGHA---RARVFREVETFHHCQGHLGILQLIEFFE-DDEK--FYLVFEKINGGPLLSRIQ
 ..  . |||||. .|  ..       |... |||..     |    |.  .||... ..   |  |..|.     ..|    |.|.|   .| ||.  .
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EH----ICFSEHEASQIIKEIASGLDFLHKKGIAHRDL
.|      .. ..  |.  .||.|...|. |.. ||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL