Gene Nak (Fruit Fly)

Nak

Species: Fruit Fly
Alias: Nak, SFO113, CG10637, Numb-associated kinase, nak
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 37B7,

Classification

Group: Other
Family: NAK
Subfamily: BIKE

Sequence

Name Sequence Type Origin Length Description Download
Nak.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 270 Kinase domain by global Sugen HMM Fasta, JSON
Nak.AA Protein Various 1460 None Fasta, JSON

Protein domain

Protein domains of Nak.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Nak.AA BIKE 46-313 70 2.2e-210 705.19 In-house 1-267 (267) Show / Hide 
Range on Protein: 46-313
Range on HMM: 1-267/267
Sequence Identity: 70% (192 aa)

VTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKHHMLAMMNARL
||||..|||||||||||.|...|     .|.|||||||||||||||..||.||....||||||.||||..|...||||.|...||.||.|....|||.||
VTVEEQLAEGGFAMVFLVRDHKG-----NKCALKRMYVNNEHDLNVCCREHQIMKQCSGHKNIVGYVDCYINCIGNGVWECMILMEYCRHQVVNMMNQRL

HVG--FTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAG--NFVLCDFGSATAKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLYGGKS
..|  |||.|||.||||..|||||||.||||||||||||||||..|.|  ..|||||||||.|.||||.|||..|..||.||||..||||||||||.||.
QQGQYFTEQEVLQIFCDVCEAVSRLHHCQTPIIHRDLKVENILLHDHGPPHYVLCDFGSATNKFLNPQKHGVNYVKDEIEKYTTMCYRAPEMIDLYSGKE

ITTKADIWALGCMLYKLCFFSLPFGESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEV
||||||||||||||||||||.||||||.|||..|.|.|||.||||..||.||.|||||||||||.|.||..|
ITTKADIWALGCMLYKLCFFCLPFGESQLAICDGNFTIPDNSKYSREMHCLIRYMLEPDMEKRPDIYQVSHV
Kinase Nak.AA NAK 46-314 49 9.69999999999e-170 570.19 In-house 1-299 (299) Show / Hide 
Range on Protein: 46-314
Range on HMM: 1-299/299
Sequence Identity: 49% (148 aa)

VTVEDVLAEGGFAMVFLARGN-----GGGSSSATKYALKRMYVN-NEHDLNVAKREIQIASNLSGHKNIIGYVDSSIT-PT-GNGVCEVLLLMPYCKH-H
.||| .||||||..|.|...|     ....|...|||||||... .|.|||..||||..  .|..|.||..|.||.|. .  .||..||.|||.||.| .
YTVEKYLAEGGFSYVYLVQDNYINHPDNPNSNGEKYALKRMICHSDEQDLNACKREIEMMKKLQHHNNIVQYIDSHINERDDSNGTWEVFLLMEYCCHGS

MLAMMNARLH-VG--FTEPEVLNIFCDIAEAVSRLHYCQT--PIIHRDLKVENILQTD---AGNFVLCDFGSATAKTLNPQQ-HGVTV---VQEEIQKYT
.. .||.||.  |  ||| |.|.||||..|.|...|.||.  ||||||.|.||||. .    ||..||||||.| ....|.. ...     ||..|.|||
LWDLMNKRLMDKGTCFTEDEILQIFCDVCEGVQAMHQCQPPKPIIHRDIKIENILLSESHHDGNYKLCDFGSMTTAIIQPENRWEAQYRSMVQDWINKYT

TLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPFG-------ESTLAIQNGQFS--IPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVA
|..||||||.||| .. |..|.|||||||||||.||. .||.       .|.||||||...  |||.|.||..||.||.|||.||.|.||||.||....
TPMYRAPEMCDLYSNCPIDEKVDIWALGCMLYKMCFYTHPFEDCYQRHDSSKLAIQNGNYKYSIPDNSRYSQQMHDLIRYMLTPDPEQRPNIYQVLNQL
Kinase Nak.AA NAK-Unclassified 46-316 28 7.7e-88 298.13 In-house 1-405 (405) Show / Hide 
Range on Protein: 46-316
Range on HMM: 1-405/405
Sequence Identity: 28% (114 aa)

VTVEDVLAEGGFAMVFLAR--------GN--GGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSIT--PTGNGVCEVLLLMPYC
.|.   ||||||. |.|..         |    ..| . .|.|||| .  |  || .|||| .   . .|.||. | |..|     .|.  ||..||.||
YTIVRYLAEGGFSFVYLVKFSKYINPPDNTASVPHSNSNMYCLKRMICQDEESLNTMKREIDVMKRFRNHPNIVKYIDHHIMRENHNNQSYEVFMLMEYC

KH-HMLAMMN------ARL--HVGFTEPEVLNIFCDIAEAVSRLHYCQT--------------------------------------------PIIHRDL
.  . .  ||      .||     |.| |.| |. |...... .|. |                                             |.||||.
SRGSLQDFMNNQRTIYQRLTEQTRFHEQECLQIMSDVCQGIQCMHQHQPRQDNATSRVNVDAVSMTYSDETAMLLEDTPLEMDMLSSNSAGSIPLIHRDI

KVENILQT---------------------------------------------------------DAG-NFVLCDFGSAT--AKTLNPQQHGVTVVQEEI
|.||.|                                                           . . ...||||||..   .| .  |     .|..|
KIENVLFCNLRRPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSEDSEHNGIYKLCDFGSCCECIITIENRQE-MQYLQDWI

QKYTTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPFG-ESTLA-------IQN--GQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQV
 ..||. |||||||||| .  |  | ||||||| |||.||.  ||  .  |.       | .  | ...|. ..|| . |.||| || .|   |||| ||
NMHTTPQYRAPEMIDLYRCCPIDEKIDIWALGCFLYKMCFYTTPFEMCGQLHNASVTYKILHGLGKYEFPSNHNYSNQLHNLIKIMLNEDPIQRPNIYQV

CEVAFR
 .   .
LNHICQ
Kinase Nak.AA GAK 48-314 36 7.5e-62 204.29 In-house 3-277 (277) Show / Hide 
Range on Protein: 48-314
Range on HMM: 3-277/277
Sequence Identity: 36% (104 aa)

VEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPT---GNGVCEVLLLMPYCKH----HMLAM
|. |.|||||| |..|   . |    . ||||||  . .        || .   |.|| ||.  .|.| .       .. | |||| |||      .|  
VRCVIAEGGFAFVYVAQDVQTG----REYALKRMLSHDMQANRAIINEICMMKKLQGHENIVQFCDASYISREESNQSQAEYLLLMEYCKFSQLVDCLKR

MNARLHVGFTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQ----HGVTVVQEEIQKYTTLSYRAPEMIDL
|  .  .  .   || ||   . ||  .|    ||||||.|.|| |    .   |||||||| | . |           |..|. ..||  || |||.||
MECYKPFSCD--CVLRIFYQMCRAVQHMHSQKPPIIHRDIKIENFLIGNQKTIKLCDFGSATTKSHYPDYSWSAQKRSMVEDEMFRHTTPMYRSPEMCDL

YGGKSITTKADIWALGCMLYKLCFFSLPF-GESTLAIQNGQFS--IPD-SSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVA
|    |  | ||||.||||| .|.   ||   . |.| ||  .  ||    .|.   | ||  .| .. . |. | .| |  
YSNWPIGHKQDIWAMGCMLYFMCYRQHPFEDGAKLRIINGNYMKPIPPQDNQYMC-FHDLIRACLQVNPDERLDIAMVVEYM
Kinase Nak.AA S_TKc 46-315 22 2.3e-42 147.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 46-315
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

VTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKH---HMLAMMN
 .. ... .|.|. |...| ..    .  ..|.|..        . ..||||| ..  .|.||. . |.  .       .. . | || .    .. .. 
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK-------EHIRREIQILKK--HHPNIVKLYDVFQD------DHLYMVMEYCDGDLGDLFDYIK

ARLHVG----FTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLYG
 | . |    |.| ..  ... |..|.  .|     ||||||| |||| ..  .  .||||.|.                      |. |.|||..    
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL---------------TTFCGTPWYMAPEVL----

GKSITT-KADIWALGCMLYKLCFFSLPFGESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCE--------VAF
  . .. |.|.|..||.|| ..    ||     .. .           |. . ..|. .|. | |||| . .. .          |
--GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Nak.AA Pkinase 46-312 22 1.3e-37 134.13 Pfam 1-289 (293) Show / Hide 
Range on Protein: 46-312
Range on HMM: 1-289/293
Sequence Identity: 22% (71 aa)

VTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNV--AKR--EIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKH-----H
 ... .. .|.|. |....  | |     ..|.|.. . .|..     . |  ||||  .| .|.||. . |.  .       .. . |.|| .      
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED-----KDHIYMVMEYCEGGLYVMD

MLAMMNARLHVGF--TEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNF----VLCDFGSATAKTLNPQQHGVTVVQEEIQKYT-TLSYR
  ... .. | .|  .| |. ...  |....  .| .   ||||||| ||||  . |.      .||||.|  .         .  ..  . .. |. |.
LFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------Y-NNS-MTTFCGTPWYM

APEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPFGES-----------TLAIQNGQFSIPDSSKYS-------------------KGMHQLIKYMLEP
||| |   ||. ...|.|.|..||.|| ...  .|| ..              |  .... . . ..|                   . . ..||..|..
APEVIR--GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCK

DMEKRPNIWQVCE
|..|||.. |...
DPKKRPTAEQILQ
Kinase Nak.AA MPSK 47-314 32 2.1e-35 123.97 In-house 2-281 (281) Show / Hide 
Range on Protein: 47-314
Range on HMM: 2-281/281
Sequence Identity: 32% (93 aa)

TVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDS-SITPTG----NGVCEVLLLMPYCKHHMLAMM
..   |.|||| .| |    . . .   .|||||       | | |.||.     .  |.|||. ||  ..   .    |.. |..|. || ||  |.  
YFMQRLGEGGFSYVDL----VENLHDGHFYALKRIQCHEQQDQNQAQREAEMHCQFD-HPNIIRLVDWGCLKGREDIVINTKHEIWLVLPYFKHGTLWDH

NARLHVG---FTEPEVLNIFCDIAEAVSRLH-YCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQ-QHGVTVVQEEIQKYTTLSYRAPEMIDL
  |.       ||  .. ||  . | .  .|     |  |||.|  ||.  | .  |. |.|| .   .  . |      | .     ...|||||    
LQRMKDKGDCMTEDQIWWIFLGVCEGLKAIHEAMPKPYAHRDMKPTNICLGDDFQPVIMDLGSMNEACIQVKGQRQACALQDWAAERCSMVYRAPELFHV

YGGKSITTKADIWALGCMLYKLCFFSLPF------GES-TLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVA
     |  . ||| ||| ||  |.|  |.      | |  ||.||..|.||..| || .|||||.||.  |   ||.|  |    
QSHCVIDERTDIWSLGCVLYAMCYFHSPYDMIYQRGDSVHLAVQNRNFNIPENSRYSQDMHQLISYMMRVDPMERPHIFWVLNQT
Kinase Nak.AA TKL-ciliate1 160-314 26 2.9e-32 107.72 In-house 111-279 (279) Show / Hide 
Range on Protein: 160-314
Range on HMM: 111-279/279
Sequence Identity: 26% (46 aa)

DIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATA----KTLNPQQHGVTVVQEEIQKYTTLSYRAPEMID--LYGGKSITTKADIWALGC
|||  .. ||  | |.||||||..|||     ..  |.|.. .     ..   .      .|.|.|. ||  ..||| .|  .. .. |..|.||.|.| 
DIAQGMQYLHMRQNPLIHRDLKMQNILYDEPYQYKICNFPHVKIADFHRI---RNCSFQDMQNEMQRNTTFHWMAPEQMDPHIFPNYPINEKIDIYAYGI

MLYKLCFFSLPFGESTLAIQNGQFSIPDSS------------KYSKGMHQLIKYMLEPDMEKRPNIWQVCEVA
 .| |||   || .. .   |..  ...              ...  .|.|.. ... .  ||||  .. .. 
VMYILCFRKTPF-QQKMSVINIMCYWCEFPGRPNLGPQFIHFDCPQNFHNLMMRCWCQNPNKRPNFNEIIQIL
Kinase Nak.AA CAMK 51-307 18 2.1e-31 97.9 In-house 1-416 (425) Show / Hide 
Range on Protein: 51-307
Range on HMM: 1-416/425
Sequence Identity: 18% (77 aa)

VLAEGGFAMVFLARGN-GGGSSSA-------TKYALKRMYVN----------------------------NEHDLNVAKREIQIASNLSG------HKNI
.| .|.|. |.|..    .|   .       .|.| | .  .                            ...|.   .|||.| ..|.|      |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IGYVDSSITP----------TGNG--VCE----VLLLM---PYCKH-----HMLAMMNARLH-------------VGFTEPEVLNIFCDIAEAVSRLHYC
|   .   .|          | .   . .    . . |    ||        .. .  .. .               ||| |.  .|  |..||  .| .
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

QTPIIHRDLKVENILQTDA-----------------GNFVLCDFGSATAKTLNPQQHGVTVVQEEIQ---------------KYTTLSYRA-PEMIDLYG
   |.||||| |||| .|                  .|  ..||| |. .. . ...  . .... .                  |..| | ||..   |
N--IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

-----------GKSITTKADIWALGCMLYKLCFFSLPFGESTL------------------AIQNGQFS-IPD-------------SSKYSKG-------
            . .. |.|.|..|..|| .    .|| ...                    |..|... .|.              .. |.        
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQ

-MHQLIKYMLEPDMEKRPNI
   .||. ||..| |||..|
ECKDLIRKMLQVDPEKRMTI
Kinase Nak.AA Ciliate-E2-Unclassified 149-312 22 7.2e-28 93.76 In-house 135-348 (352) Show / Hide 
Range on Protein: 149-312
Range on HMM: 135-348/352
Sequence Identity: 22% (48 aa)

FTEPEVL-----NIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAG---NFVLCDFGSATAKTLNPQQHGVT------VVQEEIQKYT--TLSYR---
||| ...     ..|  | .. . ||. .  |||||.| |||| .. |   .  ..|||..     |...   .      . ...... .  |..|    
FTEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQY

-APEMI--DLYGGKSITTKADIWALGCMLYKLCFFSLPFG---------------------ESTLAIQNGQFSIPDSSK--YSKGMH--------QLIKY
 |||..    |....   |.|||.||. || ..|  .||.                     .    |.......| ...   .|. .        .|.. 
TAPEVLQGQNYDHSKA-YKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQK

MLEPDMEKRPNIWQVCE
||. ...||....|...
MLKKNPNKRITFEQILN
Kinase Nak.AA Ciliate-E2 168-310 23 2.1e-27 91.14 In-house 173-359 (365) Show / Hide 
Range on Protein: 168-310
Range on HMM: 173-359/365
Sequence Identity: 23% (47 aa)

LHYCQT-P-IIHRDLKVENILQTDAGNFVLCDFGSAT-AKTLNPQQHGVTVVQEEIQKYT------------------------TLSYRAPEMIDLYG--
|.|.     |||||.| ||||        ..||| .. ... | .. .  . .....                           |. | |||..   .  
LEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYD

----GKSITTKADIWALGCMLYKLCFFSLPFGESTLAIQNGQFSIP----------------DSSKYSKGMHQLIKY----MLEPDMEKRPN-IWQV
    .|  ..|.|||.||..|| ..|  .||      |.......|                .  | |. . .|||     ||. | |||.. ..|.
NQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase Nak.AA CAMKL 46-312 25 3e-25 77.39 In-house 1-293 (297) Show / Hide 
Range on Protein: 46-312
Range on HMM: 1-293/297
Sequence Identity: 25% (79 aa)

VTVEDVLAEGGFAMVFLARG---NGGGSSSATKYALKRMYVNNEH-DLNVAKR--------------EIQIASNLS--GHKNIIGYVDSSITPTG--NGV
 .....| .|.|. | ||.    .       .|.| | .  .    | .. |.              |||| . |.  .|.|||   .   ||.      
YRIGKTLGKGSFGKVKLATHIRTT------GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIET-

CEVLLLMPYCKHH---MLAMMNARLHVG--FTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAG--NFVLCDFGSATA---KTLNPQQHGV
 .. | | ||      .. .  .. |..  ..|.|   .|. | .||. .| .   |.|||.| |||| .. |  |  ..||| ..    .         
KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG--IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC---------

TVVQEEIQKYT---TLSYRAPEMIDLYG--GKSITTKADIWALGCMLYKLCFFSLPFGESTL------------AIQNGQFSIPDSSKYSKGMHQLIKYM
 .....    |   ...| |||..   |   . .  |.|||..| .|| . .  ||| . |.             |  | . .|  .. |   ..||. |
-IFGPGQKLKTFCGSPPYMAPEIF--QGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKM

LEPDMEKRPNIWQVCE
|... ||||.| |. .
LQVNPEKRPTIHQIMN
Kinase Nak.AA TyrKc 46-314 19 2.9e-08 -89.06 SMART 1-280 (280) Show / Hide 
Range on Protein: 46-314
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

VTVEDVLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNL-SGHKNIIGYVDSSITPTG-----NGVCEVLLLMPY--CKHHM
.| ...| || |  |.... .       .. | | .  .    .    ||..| ..|   |.||.  .   ... .       .. |. .||.  .|.. 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

LAMMNARLHVGFTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQ-----QHGVTVVQEEIQKYTTLSYR--A
 .  .      .. .. |..  .||.  . ||    ..|||||   |.| .. .    .|||   .. .         . . ...|. .. | | .|  |
RKHRPK-----LCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFG--LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEMIDLYGGKSITTKADIWALGCMLYKLCFF-SLPFGE--------STLAIQNGQFSIPDSSKY---------SKGMHQLIKYMLEPDMEKRPNIWQVCE
|| |  ||    ||| |.|. | ... .. .   |  .        . .  .  |   ..  ..         .. |.|..|   . | |.||. ....|
PECI-NYG--KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHE

VA
  
CF