Gene png (Fruit Fly)

png

Species: Fruit Fly
Alias: png, EG:8D8.5, fs(1)M2, pan-gnu, Png, CG11420, PNG, SFO056
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 1F4,

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
png.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
png.AA Protein Various 291 None Fasta, JSON

Protein domain

Protein domains of png.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc png.AA S_TKc 8-282 25 1.1e-63 218.8 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-282
Range on HMM: 1-231/231
Sequence Identity: 25% (72 aa)

LRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTELGLIKEEVYIISQLRHPHIVEFLRSFSHAGTVNIVMEYVPN--GTLRDVIQQLPSG
 . .|..|.|.||.|..|. ..      |.| .|.|           |. |. | .. .||.|| .. .| . . . .||||...  |.|.|.|.. ...
YEILRKIGKGAFGKVYKCRHKK----TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

TGG--VNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMSSQGKVDF-KSDVWSLGLVL
 ..   .  .   |.. .. .|||.| . .||||.|||| |||   ..||.|||.| .           ||| ||||| .    . .. |.|.||.| .|
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

YELCLGRSPFAAFLDKNATPALLHTVVQALVRPRLDCQLIRRLYDPVWAQVCELMVVYEQERRICLPDIFH--LDAGMTVTL
||.. |. ||        .....  ..                 .|   .  . . ... |.|.   ....  .|. .   .
YEMLCGYPPFP-------QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase png.AA Pkinase 8-212 33 3.4e-57 201.12 Pfam 1-212 (293) Show / Hide 
Range on Protein: 8-212
Range on HMM: 1-212/293
Sequence Identity: 33% (75 aa)

LRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTELG--LIK-EEVYIISQLRHPHIVEFLRSFSHAGTVNIVMEYVPNG----TLRDVIQ
.. .|..|.|.||.|..||    .     .|.||.| .|. | .    ...  |..|   |.||.||.....|   . . .||||...|     | |.|.
YHIGRKIGSGSFGCVYKCHHKGTGK----IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

QLPSGTGGVN--QERLMG-YFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRV----KIADFGIANV--HAPSTQLQAGMGTPMYMAPEAMSSQGKVDF
      .|.   .|.    |.. .. ||||.| . .||||.|||| |.| |. .    ||.|||.| .  . ... ..   ||| |||||   .. . . 
T---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDVWSLGLVLYELCLGRSPF
|.|.||.|..|||...|| ||
KVDMWSCGCILYEMLCGRPPF
Kinase png.AA CAMK 13-212 21 3e-52 166.29 In-house 1-334 (425) Show / Hide 
Range on Protein: 13-212
Range on HMM: 1-334/425
Sequence Identity: 21% (71 aa)

VLGQGTFGRVFLCHQNEVRGQPE--------RKVCVKRII-----------------VRNPKTE----------LGLIKEEVYIISQ-------LRHPHI
.||.|.|| |.|| . .  |. .        .|| .| |                  ... |.           .  .. |. | ..       |.||.|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VEFLRSFS------------HAGT--------VNIVM---EYVPNG----TLRDVIQQLPSGT-----------GGVNQERLMGYFRDMVVGLEYLHIRC
. ..  .                .        . .||   ||...|     | | |.. ....           | .. .    ||| .. ...|.| . 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIHRDIKPENMLLDAND-----------------RVKIADFGIANVHAP------------------------STQLQAGMGTPMYMA-PEAMSS-----
..|||.|||| ||| |.                  .||.||| ||.  |                           ..   ||| ||| ||  ..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QGKVDFKSDVWSLGLVLYELCLGRSPF
        .  ...|.|.||.| .|| .  |..||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPF
Kinase png.AA STE 8-213 24 6.8e-51 175.4 In-house 1-269 (359) Show / Hide 
Range on Protein: 8-213
Range on HMM: 1-269/359
Sequence Identity: 24% (66 aa)

LRAVRVLGQGTFGRVFLCHQNE-----VRGQP------ERKVCVKRIIVRNPK----------------TELGLIKEEVYIISQLR--HPHIVEFLRSFS
.. ....|.|.|| |...  ..       |.        . . .|.. ..| .                .|.  |..|. | ....  ||.||... .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HAG-------TVNIVMEYVPNGTLRDVIQQ--LPSGTGGVNQ-------ERLMGYF-RDMVVG-LEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIAN
. |       ...|.|||...|.|.|.|..   . ..   |.       | . .|. |. . | |.|||   .||||||| | ||     ||..|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

VHAP-----------------STQLQAGMGTPMYMAPEAMSS-----QGKVDFKSDVWSLGLVLYELCLGRSPFA
  ..                 . . .   ||| .|||| ..       .. |.|.|.||||... |.. |. |..
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWH
Kinase png.AA TKL 14-213 21 2.1e-49 170.48 In-house 1-290 (364) Show / Hide 
Range on Protein: 14-213
Range on HMM: 1-290/364
Sequence Identity: 21% (65 aa)

LGQGTFGRVFLCHQNEVRGQPE-----RKVCVKRIIVRN--------------------------PKTELGLIKEEVYIISQLRHPHIVEFLRSFSHAGT
.|.|.|| |.  . .  .|  .     . | ||.. ..|                          .. .   ..||. ..|.||||.|| |. .    . 
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

-------------VNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHI--------RCVIHRDIKPENMLLDANDR-----------
               |||||.|.|.|.....           ....   .|.  |..|||         . .||||.|..| |.| | .           
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---VKIADFGIANVHAPSTQLQAG--------------------MGTPMYMAPEAMSSQ---------------GKVDFKSDVWSLGLVLYELCLGRSPF
   .||.|||.. .. .|.. ...                     ||| .||||..  |               .. . |.||.| |.||.|.. .. |.
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

A
.
Y
Kinase png.AA Ciliate-E2 8-219 21 1.1e-47 161.81 In-house 1-300 (365) Show / Hide 
Range on Protein: 8-219
Range on HMM: 1-300/365
Sequence Identity: 21% (68 aa)

LRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRI----------------IVRNPKTELGLIKEEVYIISQLR----------------HPHIVEFLR
   ....|||.|| |..| . .|. |   |.   ..                . .. | ..  || | .|. ...                ||.|...  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYE

SFS--HAGTVNIVMEYVPNGTLRDVIQQLPS--------GTGGVNQERLMGYFRDMVV---------------GLEYLHIRC-VIHRDIKPENMLLDAND
.|      .. .||||.  |.|.| |.. .         . .  . .    ...  .                .||||| .  .||||||||| |.    
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

RVKIADFGIA-NVHAP----------STQLQAG----------------------MGTPMYMAPEAMSSQGK--------VDFKSDVWSLGLVLYELCLG
 .||.|||.. ... .             .. .                       |||.|||||  ....          |.|.|.|||| .|||.. |
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG

RSPFAAFLDKN
. ||   ....
KPPF---QQQI
Kinase png.AA Ciliate-E2-Unclassified 9-212 27 8.3e-44 149.84 In-house 2-270 (352) Show / Hide 
Range on Protein: 9-212
Range on HMM: 2-270/352
Sequence Identity: 27% (74 aa)

RAVRVLGQGTFGRVFLCHQNEVRGQP------ERKVCVKRIIVRNPKTELGLIKEEVYII----------------SQLRHPHIVEFLRSFSHAGTVNIV
. ....||| || |..| ...   |         .  .|. ...| . |. ....|. ..                ... ||.|| ..  |    .. ||
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYVPNGTLRDVIQQLPS------------GTGGVNQERLM------GYFRDMVVGLEYLHIRC-VIHRDIKPENMLLDAND---RVKIADFGI------
|||...|.|.. |.. ..             ..   .|. .       ||.  ..||||||    .||||||||| |.| |    ..||.||||      
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------ANVHAPSTQLQAGM-GTPMYM----APEAMSSQGKVD---FKSDVWSLGLVLYELCLGRSPF
         ..   .. |..  . |||.||    ||| . .|.  .   .|.|.|||| .|||.. |. ||
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPF
Kinase png.AA CAMKL 8-203 29 2.6e-43 135.96 In-house 1-227 (297) Show / Hide 
Range on Protein: 8-203
Range on HMM: 1-227/297
Sequence Identity: 29% (68 aa)

LRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPK-TELGL-------------IKEEVYIISQLR---HPHIVEFLRSFSHAGT------VN
 | ...||.|.|| | |..        ..|| .| |  .  .  .  .             |. |. | ..|.   ||.|. ..  .    .      ..
YRIGKTLGKGSFGKVKLATHIRTT---GEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIY

IVMEYVPNGT--LRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDAND--RVKIADFGIANVHAP-----STQLQAGMGTP
.||||...|   | | |.. . . |    .    ||| .| ...|.| ....|||||||| ||| |.   .||.||| .| . |        |    |.|
LVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSP

MYMAPEAMSS--QGKVDFKSDVWSLGLVLY
 |||||  ..  .    .| |.||.| .||
PYMAPEIFQGNNKPYDGPKVDIWSCGVILY
Kinase png.AA MARK 9-219 31 1.6e-41 133.62 In-house 2-215 (262) Show / Hide 
Range on Protein: 9-219
Range on HMM: 2-215/262
Sequence Identity: 31% (69 aa)

RAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTE---LGLIKEEVYIISQLRHPHIVEFLRSFS--HAGT-VNIVMEYVPNGTLRDVIQQL
. ....|.|... | |..    .    |||..| |. .. ...   .  .. |. | ..| ||.|....  .   . .. ....|||...| |.| |.. 
KMLKTIGHGSYAKVKLACHKHTG----RKVAIK-IYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAH

PSGTGGVNQERL-MGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDAND--RVKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMSSQGKVDFKSDVWSLG
|   .|  .|..   .|| .| ...|.| . ..|||||||| |.|.|    .||.||| ..   | . |    ||| ||||| ....    .| |.||||
P---NGRLHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLG

LVLYELCLGRSPFAAFL--DKN
 ||| .  |. || .    .|.
VVLYFMVCGYFPFDGDTQDYKE
Kinase png.AA ULK 8-214 26 4.1e-41 141.29 In-house 1-258 (329) Show / Hide 
Range on Protein: 8-214
Range on HMM: 1-258/329
Sequence Identity: 26% (70 aa)

LRAVRVLGQGTFGRVFLC--HQNEVRGQPERKVCVKRII---VRNPKTE------LGLIKEEVYIISQLR--------HPHIVEFLRSFSHA--GTVNIV
    ..||.|.||.|.    .... . .   || .| |     .. . |      . |.| |. |. .|         ||.||...  |  .    . |.
YCLNHCLGKGSFGKVYKGRNKKTK-D-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYII

MEYVPNGTLRDVIQQLPS------GTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDAND------------RVKIADFGIANV-HAP--S
||| . |.|.. |..           .  ...    .|.. . |. .|| . .|||||||.| |.. ..            ..|||||| | .   .  .
MEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

TQ-LQAGM------GTPMYMAPEAMSSQG---KVD-FKSDVWSLGLVLYELCLGRSPFAA
 | ...        |||.||||.  ..||   . . .|.|.|||| ..||.  |. || |
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYA
Kinase png.AA NEK 9-206 33 4.9e-41 142.38 In-house 2-218 (286) Show / Hide 
Range on Protein: 9-206
Range on HMM: 2-218/286
Sequence Identity: 33% (74 aa)

RAVRVLGQGTFGRVFLCHQ---NEVRGQPERKVCVKRIIVRN-PKTELGLIK-EEVYIISQLRHPHIVEFLRSFSHAG--TVNIVMEYVP-NGTLRDVIQ
. ....||| ||.|...     . . .  | ... |.| . |    |      .|| | .||.||.||..  || . .  . .|||||   .|.| . |.
EIIKKIGQGSFGKVYKVRRKSDGKHLV--EKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIK

QLPSGTG---GVNQERLMGYFRDMVVGLEYLHIR-----CVIHRDIKPENMLLDANDR----VKIADFGIANVHAPST-QLQA-GMGTPMYMAPEAMSSQ
..  ...       |  . .|  |. .| |.| |      ..|||||| |  |..|..    ||| ||||. |   .|  ..    ||| ||.|| ....
SIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTTDMAYTTQVGTPYYMSPEVCQNK

GKVDFKSDVWSLGLVLYELC
 . ..|||.|||| ||||.|
-PYNNKSDIWSLGCVLYEMC
Kinase png.AA ULK 8-212 28 4.5e-38 132.69 In-house 1-252 (324) Show / Hide 
Range on Protein: 8-212
Range on HMM: 1-252/324
Sequence Identity: 28% (72 aa)

LRAVRVLGQGTFG-RVFLC--HQNEVRGQPERKVCVKRII---VRNPKTE------LGLIKEEVYIISQLR---HPH--IVEFLRSFSHA--GTVNIVME
    ..||.|.||  |.    ....       .| .| |     .. | |      . |.| |. |. .|    ||.  ||...  |  .    . |.||
YCLNHCLGKGSFGVKVYKGRNKKTNT---QNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIME

YVPNGTLRDVIQ---QLPSGT---GGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDAND------------RVKIADFGIANV-HAPSTQLQ
| . |.|.. |.    ||  |   .  ...   ..|.. . |. .|| . .|||||||.| |.  ..            ..|||||| | .   .. . |
YCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQ

AGM---------GTPMYMAPEAMSSQG---KVD-FKSDVWSLGLVLYELCLGRSPF
  .         |||.||||.  ..||   . . .|.|.|||| ..||.  |. ||
MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPF
Kinase png.AA Pkinase_Tyr 8-213 27 5.1e-27 92.13 Pfam 1-217 (270) Show / Hide 
Range on Protein: 8-213
Range on HMM: 1-217/270
Sequence Identity: 27% (60 aa)

LRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTE--LGLIKEEVYIISQL-RHPHIVEFLRSFS-HAGT--VNIVMEYVPNGTLRDVIQQ
..  ..||.| ||.|.... .   .... .| || .     . .  .    .|. | .|| .||.|| ..   . . .   . |||||.|.| |.|  ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

LPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANVH-----APSTQLQAGMGTPMYMAPEAMSSQGKVDFKSDVW
  .. . .. ..| .. ..   |.|||. .  ||||.   | |.. |  |||.||| |  .       ... . |.     ||||...       |||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

SLGLVLYELCL-GRSP-FA
| | ...|..  |..| ..
SFGVLMWEIFTYGEQPTYP
Kinase png.AA TyrKc 8-257 22 9.7e-17 47.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-257
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

LRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTELGLIKEEVYIISQL--RHPHIVEFLRSFSHA-------GTVNIVMEYVPNGTLRDV
..  ..|| | ||.|.... .       ..| || .        .  . .|  | ..|  .||.|| ..   ..        . . |||||.|.| |.| 
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY

IQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIANVHAPS--------TQLQAG--MGTPM----YMAPEAMS
..        .. . |  .  .   | |||| ...||||.   | |...| .|||.||| .  .           .  ...   |  |     ||||.. 
LRKHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

SQGKVDFKSDVWSLGLVLYELC-LGRSPFAA--FLDKNATPALLHTVVQALVRPRLDC----------QLIRRLYDPVWAQ----------VCELM
  ||  .|||||| | ...|.. .| .|     .  .     ... | |   .|. .           . . ..    |.           ..|..
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF