Gene PKA-C3 (Fruit Fly)

PKA-C3

Species: Fruit Fly
Alias: 5-23, PKA-C3, Dpck, CG6117, PKA C3, Pk72A: Protein-kinase-like-72A, SFO190, PKA, Protein-kinase-like-72A, Pk?5, DC2
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 72B1--2,

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
PKA-C3.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 255 Kinase domain by global Sugen HMM Fasta, JSON
PKA-C3.AA Protein Various 500 None Fasta, JSON

Protein domain

Protein domains of PKA-C3.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase PKA-C3.AA PKA 191-445 63 2.3e-204 685.24 In-house 1-263 (263) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-263/263
Sequence Identity: 63% (168 aa)

YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVI-SLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQ
..||.|.|||.||||.|||...|..|.|||.| ..|..||||.|||.||.|||..|.|||.. ...|...||..|||...||.|||.|.|||. |.|...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TSNFYAA-EIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSK-GHNKAVDWWALGVLIYEMLVGYPPFY
...|||| .||.|||||||..|.||||||||.||...||.||||||||||..||||||||||||.|||||||| ||.|.|||||||.||||||.||||||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

DE--QPFGIYEKILSGKIEWERHMDPIA---KDLIKKLLVNDRTKRLGNMKNGADDVKRHRWF
|.  .|..|||||..|||...||.|. |   ||||||||..|.|||.||||||..|.|.|.||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase PKA-C3.AA AGC 191-445 32 3e-183 478.87 In-house 1-395 (395) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-395/395
Sequence Identity: 32% (131 aa)

YQIIKTVGTGTFGRVCLCRDR------ISEKYCAMKILAMTE-VIRLK--QIEHVKNE------------RNILREIR----------HPFVIS-LEWST
....|..|.|.||.|.|.|..       ..||.|||.|   . ....|  ..||...|            |||| ...          |||... |  | 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDDSN--LYMIFDYVC---------GG-ELFTYLR---NAGKFTSQTSNFYAAE-------IVSALEYLHS-LQIVYRD-LKPENLLINRDGHLKITDFG
.|...  ||.. .|..         || |||..|.   . |.|. ... |||||       ||.||||||| . |..|| |||||.|...|||.|.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKKLR-----------------------------------------------------DRTWTLCG--TPEYIAPEIIQSKGHNKAVDWWA--LGVLIY
..|...                                                     |||||.||  ||||.||||.    ..||.|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLVGYPPFYDE----------QPFGIYEKIL------SGKIEWE----------RHMDPIAKDLIKKLLVNDRTKRLGNMKN-----GADDVKRHRWF
|||.||||||..          .|. ...||.      . |...           |...| |||||||||. |..||||...|     ||...|.| ||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase PKA-C3.AA Akt 191-445 44 1.1e-122 393.98 In-house 1-264 (264) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-264/264
Sequence Identity: 44% (118 aa)

YQIIKTVGTGTFGRVCLCRDRISEKYC-AMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQ
 ...|  | |.||.| |...  ..|.  |||.|     |  .|.||.| |||||  ..|||...|  |  .  .||.. ||. |||||..|. ...|. .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

TSNFYAAEIVSALEYLHSLQIVYRD-LKPENLLINRDGHLKITDFGFAKKL---R-DRTWTLCGTPEYIAPEIIQSKGHNKAVDWWA-LGVLIYEMLVGY
.  ||.|||..|.|.|||  |.||| |||||.|. .|||...|||| .|.    . |.| |.||||||.||||.. .|| ||||||. ||...|||. | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYDEQPFGIYEKILSGKIEWE--RHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWF
||||...    ..||......    .  .| .||||..||  |..||||. .|.|...||| ||
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase PKA-C3.AA SGK 191-445 38 9.69999999999e-118 365.3 In-house 1-283 (283) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-283/283
Sequence Identity: 38% (110 aa)

YQIIKTVGTGTFGRVCLCRDRIS------------------EKYCAMKILAMTEVI-------RLKQIEHVKNER-NILREIRHPFVISLEWSTKDDSNL
 ...|..| | ||.| . .                      .|  |||.|    .|       . |.  |.. || .||  ..||| ..|  .   .  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAK---KLRDRTWTLCGTPEYIAPEIIQSK
|.  ||| |||.| .|. ...|    . |||||||.|||||||. |.||||||||.|   .||...|||| .|   |  | | | |||||| |||... .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWF
.| ..|||| || . |||..| ||||.      |..|.....   . | . |.|||. ||  |..||||  |... ..|.| .|
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLG-TKRDFMEIKNHPFF
Kinase PKA-C3.AA AktR 191-445 41 3.2e-116 392.41 In-house 1-268 (268) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-268/268
Sequence Identity: 41% (112 aa)

YQIIKTVGTGTFGRVCLCRDR-ISEKYCAMKILAMTEVIRLKQIEHVKNERNILR-EIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTS
....|  | |.||.| |....  . |. |||..  .. |...|..|. .||||.  ...||| . |. . .....|. | .|..|||||..|.. .||. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

QTSNFYAAEIVSALEYLHSL-QIVYRDLKPENLLINRDGHLKITDFGFAK--KL---RDRTWTLCGTPEYIAPEIIQS-KGHNKAVDWWALGVLIYEMLV
... ||.|.|. ||||||.   |.||||||||.|.  |||.|||||| .|  .    .... ..||||||.|||.|.  |||||.|||||.|..||||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GYPPFYDEQPFGIYEKILSGK-IEWERHMDP--IAKDLIK-KLLVNDRTKRLGNMKNGADDVKRHRWF
|.||||...   ...||..   .. . ....   .||||. ||| .. .||||  .||....|.| ||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase PKA-C3.AA S_TKc 191-445 37 1e-104 355.13 SMART 1-231 (231) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-231/231
Sequence Identity: 37% (100 aa)

YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCG--GELFTYLRNAGK---
|.|....| |.||.|..||.. . ...|.||.           ||...|..||.. .||... |  .  | ..|||...|. |  |.||.|... |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNK-AVDWWALGVLIYEMLV
   |.  .  ||...|..||||.||..|..|||||||.|...  |.||.|||.|..|     |.||||.|.|||..   |..| ..|||..|...||||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGA--DDVKRHRWF
|||||.  |.. ...||.          .| |||.|.|.|. | .||..  .  .   |.| | ||
GYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase PKA-C3.AA RSK 194-445 39 5.6e-102 345.1 In-house 1-278 (278) Show / Hide 
Range on Protein: 194-445
Range on HMM: 1-278/278
Sequence Identity: 39% (111 aa)

IKTVGTGTFGRVCLCRDRI---SEKYCAMKILAMTEVIRLKQ-IEHVKNERNILREIR-HPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGK---
.|  |.| .| | |||  .   .... |||.|   .... .  ..|.. ||||| ... |||...|  . .... ||.| .|. |||||| |.. .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINR---DGHLKITDFGFAKKL----RDRTWTLCGTPEYIAPEIIQ----SKGHNKAVDWWALGV
|.  .  ||.||||.|.|.||...|..||||||| | .    .||.|.|||||.|..      .| | |.| ||.|||..      .||.||.||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LIYEMLVGYPPFYD---EQPFGIYEKILSGK--IEWE--RHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWF
|.||||.|.|||.    ...  | ..|..||   . .    . . |||||.|.|  |  ||||  ...|...|.| ||
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase PKA-C3.AA PKG 191-445 44 1.8e-99 336.75 In-house 1-260 (260) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-260/260
Sequence Identity: 44% (116 aa)

YQIIKTVGTGTFGRVCLCRDRISE-KYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQ
 .|| | | | |||| | .    . .  |.|..   ...  .|.||. .|.||. | | .|.. |    .|.  .||      |||| | ||  |.|  .
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

TSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLR--DRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFY
|. ||.| .| |..|||.  |.|||||||||. ...| .|. |||||||..   .||| ||||||.|||||  |||  .||.||||.|..| |.| ||| 
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

DEQPFGIYEKILSG--KIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWF
   |  .|  ||.|  ..|. |.    |...||||     | |||. |||  |.|.|.||
GSDPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase PKA-C3.AA Ciliate-E2 191-445 26 3.4e-91 309.29 In-house 1-365 (365) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-365/365
Sequence Identity: 26% (103 aa)

YQIIKTVGTGTFGRVCLCRDRISEK------------------YCAMKILAMTEV-----IRLKQIEHVK----------NERNILREIRHPFVISLEWS
| .||  |.|.|| |..|...   |                  ....|| ||  .     . .||..|.           ||.|||... ||..| . ..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TK--DDSNLYMIFDYVCGGELFTYLR-------------------NAGKFTSQTSN-------FYAAEIVSALEYLHSLQ-IVYRDLKPENLLINRDGHL
 .  ||.|.|....|. ||.|| |..                    ..... |  .       ||.|.|..|||||||   |..||.||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGFAKKLR----------------------------------DRTWTLCGTPEYIAPEIIQSKG---------HNKAVDWWALGVLIYEMLVGYPP
||.|||..||.                                   . ..|.||||.| ||||...|.         .....|.|.|||..|||| |.||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FYDEQPFGIYEKILSGKIEWE------------------RHMDPIAKDLIKK----LLVNDRTKRLGNMKNGADDVKRHRWF
|        ...|. .||.                     . .. .||||||    .|. |  ||..    |..... | ||
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF
Kinase PKA-C3.AA Pkinase 191-445 30 5.4e-88 303.44 Pfam 1-293 (293) Show / Hide 
Range on Protein: 191-445
Range on HMM: 1-293/293
Sequence Identity: 30% (92 aa)

YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVK-NERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGG----ELFTYLR--NA
|.|....| |.||.|..|... ..|  |.||.   .    |...|.. .|  |.....||... |  .  |....||...|. ||    .||.|..  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GKF--TSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHL----KITDFGFAK---KLRDRTWTLCGTPEYIAPEIIQ-SKGHNKAVDWWALG
|.|  . ..  ||. .|...|||.||  |..|||||||.||...||.    ||.|||.||     .....|.||||.|.|||.|. .... ..||.|..|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

VLIYEMLVGYPPFYDE------QPFGIYEKILSGKIEWERHMD---------------------PIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWF
...|||| |.|||...       .  ....|.........  .                     . .||.||..|  | .||..     |.... | ||
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase PKA-C3.AA NDR 191-334 39 1.9e-57 175.43 In-house 1-149 (350) Show / Hide 
Range on Protein: 191-334
Range on HMM: 1-149/350
Sequence Identity: 39% (59 aa)

YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIR--HPFVISLEWSTKDDSNLYMIFDYVCGGELFT---YLRNAGK
..|||..| | ||.|.|.| . .....||||.  .|...  |. ||..|| |. | .  .|.| .|  |  |...|| . .|..|| . |    | . . 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFG
|| .   || ||.| |.|..|.. .. ||.||.|.||..|||.| ||||
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFG
Kinase PKA-C3.AA MAST 191-343 37 6.5e-50 158.9 In-house 1-154 (334) Show / Hide 
Range on Protein: 191-343
Range on HMM: 1-154/334
Sequence Identity: 37% (57 aa)

YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQT
. .|| .. | .|.|.| . . . .  |||..   . |. .....|. ||||| ... ||| ..  |   ...|.|. .|. || ... |.. | |   .
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

SNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKK-LRDRT
  .| ||.| .||||||  || |||||.|.||  .|| |.||||..|. ..|..
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDL
Kinase PKA-C3.AA MAST 346-445 50 6.9e-48 152.26 In-house 224-334 (334) Show / Hide 
Range on Protein: 346-445
Range on HMM: 224-334/334
Sequence Identity: 50% (56 aa)

LCGTPEYIAPEIIQSKG-HNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGK---IEW--------ERHMDPIAKDLIKKLLVNDRTKRLGNMK
.||||.|||||.|  .| |.|.||||..|. .|| |||.||| |. |  |...||. .   |||        .  | | |.|||.|||  |  ||||  .
CCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLG-AN

NGADDVKRHRWF
||||.||.|. |
NGADEVKQHPFF
Kinase PKA-C3.AA NDR 348-445 41 1.3e-45 138.21 In-house 243-350 (350) Show / Hide 
Range on Protein: 348-445
Range on HMM: 243-350/350
Sequence Identity: 41% (45 aa)

GTPEYIAPEIIQS-KGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEW-----ERH----MDPIAKDLIKKLLVNDRTKRLGNMKNGAD
|||.|.|||..|  .|.|...||| ||.  ||||||||||... |  ...||.. |. |     .      . | |.|||..|.  |. .|||.  .|.|
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVD

DVKRHRWF
..| | .|
EIKSHPFF
Kinase PKA-C3.AA S_TK_X 446-500 17 1e-16 62.8 SMART 1-79 (79) Show / Hide 
Range on Protein: 446-500
Range on HMM: 1-79/79
Sequence Identity: 17% (14 aa)

KHLNWNDVYS--KKLKPPILPDVH----HDGDTKNFD-DYPEKDWKPAKAVDQ------------------RDLQYFNDF
....|...|.  |...||. |...    ...||.||| ...|.... .. .|.                    .... .|
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase PKA-C3.AA TyrKc 191-439 19 4.7e-15 20.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 191-439
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

YQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREI--RHPFVISLEWSTKDD-------SNLYMIFDYVCGGELFTYLR
 . .|. | | ||.|.... .     .| | |          .|   .| .|....  .|| .. |     ..         |.... |...| |  |||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NAGK-FTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDR-------TWTLC----GTPE-----YIAPEIIQSKGHN
. .. .. ..   ..  | .  ||||| ... |||   | |...... ||.||| .... |                 |.         ||| |. .  .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWALGVLIYEML-VGYPPFYD-----EQPFGIYEKILSGKIEWERHM----------DPIAKDLIKKLLVNDRTKRLGNMKNGADDV
 . | |. ||...|..  | .| ..       .. ..|.. .|.     .           | . . ..|.    |  .|  ....  .. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRP-TFSEIHECF
Kinase PKA-C3.AA Pkinase_Tyr 191-401 25 3.8e-12 41.76 Pfam 1-232 (270) Show / Hide 
Range on Protein: 191-401
Range on HMM: 1-232/270
Sequence Identity: 25% (61 aa)

YQIIKTVGTGTFGRVCLCRDR----ISEKYCAMKILAMTEVIRLKQ--IEHVKNERNILREI-RHPFVISLE-WSTKDDSN--LYMIFDYVCGGELFTYL
 ...|. | | ||.|.... .      .  .| |.|   |    .|  .|   .| .|.... .|| ...|    |...    .|... |...| | .||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RN----AGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKL-------RDRT-------WTLCGTPEYIAPEIIQSKG
|.     ...| ..   ....| ...|||.| ... |||   | |...... ||.||| |. .       | |.       |.        ||| |. . 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM--------APECINYGK

HNKAVDWWALGVLIYEMLV-GYPP-FYDEQPFGIYEKI-LSG
 . . | |. |||..|..  |  | ...  .. .||.|  .|
FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG