Gene CG12069 (Fruit Fly)

CG12069

Species: Fruit Fly
Alias: CG12069, SFO212, PKA-like
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 100A2,

Classification

Group: AGC
Family: PKA

Sequence

Name Sequence Type Origin Length Description Download
CG12069.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 257 Kinase domain by global Sugen HMM Fasta, JSON
CG12069.AA Protein Various 356 None Fasta, JSON

Protein domain

Protein domains of CG12069.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG12069.AA PKA 47-303 54 7.29999999999e-187 627.08 In-house 1-263 (263) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-263/263
Sequence Identity: 54% (144 aa)

YEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVN-LIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEK
.||..|||.||||.|.|.|...|| |||.|.|.|..||..||| ||..|||.|.....|. |. ......|.. ||.|.....|||.|.|.||...|...
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

QARFYAA-QVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQSK-PYGTSVDWWAFGVLVFEFVAGHSPFS
.|.|||| |..|||||||.. . |||||||||..||||..|.|||||||||..||.|||||||||.||||||| ..| ||||||.|.|..|..||..||.
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFY

AHNRDVMSMYNKICEADYKMPSYFSGAL---RHLVDHLLQVDLSKRFGNLINGNRDIKEHEWF
.||||.|..|.|||....|.|..|. ..   ..|...||||||.||.||. ||..|||.|.||
DHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase CG12069.AA AGC 47-303 30 1.4e-157 410.99 In-house 1-395 (395) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-395/395
Sequence Identity: 30% (120 aa)

YEIKATLGSGSFGKVQLVRER------ESGVYYASKQLSKDQ-IVKTK--QVSHVMSE------------KNVLRSMT----------FPNTVN-LIASY
.|.. ..| |||||| |||..       .| ||| | |.|.  ||..|  .| |.|.|            .|.|  .            |. |. |  |.
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

KDFDS--LYLVLPL---------IGGG-ELFTYHR---KVRKFTEKQARFYAAQ-------VFLALEYLHH-CSLLYRD-LKPENIMMDKNGYLKVTDFG
.| |   ||.|. .         .||| |||.. .   | ..|.|..||||||.       . |||||||      .|| ||||||..|..|..| ||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

FAKKVET-----------------------------------------------------RTMTLCG--TPEYLPPEIIQSKPYGTSVDWWA--FGVLVF
..|.. .                                                     || |.||  ||||..|||.    || ..|||.  .|.| .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFVAGHSPFSAHNRD--------VMSMYNKIC------EADYKMP----------SYFSGALRHLVDHLLQVDLSKRFGNLIN-----GNRDIKEHEWF
|...|..||...|..         | |..||.      . . |.|          ..||  ...|. .||..| .|| |.. |     |  .||.|.||
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CG12069.AA Akt 47-303 41 1.2e-106 341.94 In-house 1-264 (264) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-264/264
Sequence Identity: 41% (110 aa)

YEIKATLGSGSFGKVQLVRERESGVYY-ASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEK
 ...  ||.|||||| ||..  .. .| | | |.||.|.. .|| |.. |.|.|  . .|  |||  |  . | ||.|.  ..|||||.. .. |.|.|.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QARFYAAQVFLALEYLHHCSLLYRD-LKPENIMMDKNGYLKVTDFGFAKKV---E-TRTMTLCGTPEYLPPEIIQSKPYGTSVDWWA-FGVLVFEFVAGH
.||||.|...||.|.||...  ||| ||||||.|||.|....|||| .|.    .  .|.|.|||||||.|||.. . .. .||||. .|.. .|.  | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

SPFSAHNRDVMSMYNKICEADYKMP--SYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWF
 ||  .|.|.  |. || ....|.|  ...| . . |.  ||. | .|| |. .|. ..||.|.||
PPF--YNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase CG12069.AA AktR 47-303 39 1e-97 330.97 In-house 1-268 (268) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-268/268
Sequence Identity: 39% (107 aa)

YEIKATLGSGSFGKVQLVRER-ESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLR-SMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTE
... . ||.| |||| ||... ... .|| | ..|  |.. .| .|.  |.|..   . .|  |.|  . .. . |....  . |||||....| .||.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

KQARFYAAQVFLALEYLHHC-SLLYRDLKPENIMMDKNGYLKVTDFGFAK--KV---ETRTMTLCGTPEYLPPEIIQS-KPYGTSVDWWAFGVLVFEFVA
.|||||.||. |||||||      |||||||||..|..|..| |||| .|  ..   . .. ..||||||..||.|.  |... ||||||||....| |.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GHSPFSAHNRDVMSMYNKICE-ADYKMPSYFSGALRHLVD-HLLQVDLSKRFGNLINGNRDIKEHEWF
|. || ..|.  |  . ||..    . ||||| ... |.   ||. .  || |   ||  .||.| ||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase CG12069.AA SGK 47-303 35 2.1e-97 301.37 In-house 1-283 (283) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-283/283
Sequence Identity: 35% (102 aa)

YEIKATLGSGSFGKVQLVRERES------------------GVYYASKQLSKDQIV-------KTKQVSHVMSEK-NVLRSMTFPNTVNLIASYKDFDSL
 ... ..| |||||| .|.  .                   .  ||.| |.|..|.       | |.. |.|.|. ..|  |  |  |||  .    . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLVLPLIGGGELFTYHRKVRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAK---KVETRTMTLCGTPEYLPPEIIQSK
|.|.  . |||.| . .. ..| | .||||||.. .||||||     |||||||||. |  |... |||| .|   | .. | | ||||||| ||... .
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYGTSVDWWAFGVLVFEFVAGHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWF
|.. .||||  | . .|.  |  ||   .|..  || .|   . ..| ..| . ..|   ||| | .|| |   .. ..||.| .|
PHDRTVDWWCLGCVLYEMMYGLPPF--YSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase CG12069.AA S_TKc 47-303 33 1.6e-91 311.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-231/231
Sequence Identity: 33% (90 aa)

YEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGG--GELFTYHRKVRK---
|||  ..|.|.|||| ..|....| ..| |...           |...| ..|..   || |.|. .. | |.||.|. ...|  |.||.| .| ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETRTMTLCGTPEYLPPEIIQSKPYGT-SVDWWAFGVLVFEFVA
   |.| .||||..|...||||.|    ..||||||||..|.   .|..|||.|...    .|.||||.|..||..   .||. ..|||..|....|...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GHSPFSAHNRDVMSMYNKICEADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGN--RDIKEHEWF
|  ||.    ... |..||.          |  ........||.| .|| .     .  .||| |.||
GYPPFP----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG12069.AA Ciliate-E2b 47-303 36 1.2e-89 272.59 In-house 2-272 (272) Show / Hide 
Range on Protein: 47-303
Range on HMM: 2-272/272
Sequence Identity: 36% (101 aa)

YEIKATLGSGSFGKVQLVRE-RESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVR--KFT
 .||  ||.| || | ||..  ..  ||| |. || ||...    | ..|||||. . .|. ...| |.|| ...|... .. |.|||.. | .    . 
IYIKK-LGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

EKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAK----KVE--TRTMTLCGTPEYLPPEIIQ-----SKPYGTSVDWWAFGVLV
.....|| |.. |.|||||. . .|||.|||||| |..||.|  |.| ||    | |  ||| |..|||.|. |||||      |.|...|| |..|.  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

FEFVAGHSPFSAHNRDVMSMYNKICEA--DYKMPSYFSGALR--HLVDHLLQVDLSKRFGNLINGNRDIKEHEWF
.||  |  |.    .|    | .| .   . . |||.. ..    |.. .||     | |  ..     | |.||
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYS---WLKSHPWF
Kinase CG12069.AA RSK 50-303 35 1.5e-82 280.55 In-house 1-278 (278) Show / Hide 
Range on Protein: 50-303
Range on HMM: 1-278/278
Sequence Identity: 35% (99 aa)

KATLGSGSFGKVQLVRER---ESGVYYASKQLSKDQIVKTKQ-VSHVMSEKNVLRSMT-FPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRK---
   || |..||| |.|.     .| .|| |.|.|  ||...  . |.| | |.|   .  |. |.|  .... . |||.. .. ||||||  .| .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDK---NGYLKVTDFGFAKK--VE--TRTMTLCGTPEYLPPEIIQ---SKP-YGTSVDWWAFGV
|.|. |.||.|.. ||.|.||     .||||||||. |    .| .|.|||||.|.   .   .||| |.| ||..||..     .  .. ..||| .||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LVFEFVAGHSPFSA---HNRDVMSMYNKICEAD--YKMP--SYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWF
| .|  .|..|| .    ||.. .  ..|....   .||  .| | . ..|. ..|..| .|| |   ..  .||.|.||
LMYEMLTGCPPFQGPNDNNRKEIM--KRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase CG12069.AA Pkinase 47-303 29 2.6e-79 274.57 Pfam 1-293 (293) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

YEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVM-SEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGG----ELFTYHR--KV
|.|. ..||||||.| . ... .|  .| |...|. . . |...|.  ||  .....  || | |. .. | |..|.|... .||    .||.| .  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKF--TEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYL----KVTDFGFA----KKVETRTMTLCGTPEYLPPEIIQ-SKPYGTSVDWWAF
..|  .|....||. |.. .|||.| .. ..||||||||..|.||..    |..|||.|        . ..|.||||.|..||.|. ...||..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLVFEFVAGHSPFSAH----NRDVMSMYNKICEADYKMPSYFS---------------------GALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWF
|....|.. |. ||. |    |.| | |...| ..... ... .                      ....... .|..| .|| .      ..|..|.||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase CG12069.AA PKG 47-303 40 3.6e-77 262.68 In-house 1-260 (260) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-260/260
Sequence Identity: 40% (107 aa)

YEIKATLGSGSFGKVQLVRERE-SGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSMTFPNTVNLIASYKDFDSLYLVLPLIGGGELFTYHRKVRKFTEK
 .| |||| | || | ||.  . . . .| |.. | .||.|.| .|.|||||.. .   .  | |   ..|   .|. .    |||| |  |.  .| .|
LKIIATLGVGGFGRVELVQYNHQKSRTFALKCMKKRHIVDTRQQEHIMSEKNIMMECRCDFIVRLYRTFRDQKYVYMLMEACMGGELWTILRDRGHFDDK

QARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVET--RTMTLCGTPEYLPPEIIQSKPYGTSVDWWAFGVLVFEFVAGHSPFS
 .|||.| |  |..|||   . ||||||||.| |..||.|  |||||||...  .| | ||||||  ||||  |    |||.|| |.|..|   |  |||
TTRFYCACVVEAFDYLHRKNIIYRDLKPENLMLDNRGYCKLVDFGFAKKIGQGRKTWTFCGTPEYVAPEIILNKGHDRSVDYWALGILMCELLTGNPPFS

AHNRDVMSMYNKICE--ADYKMPSYFSGALRHLVDHLLQVDLSKRFGNLINGNRDIKEHEWF
.   | |  || |        .|.  .    ... .|     . | |.. ||  ||| | ||
GS--DPMKTYNIILKGIDMWEFPRKITRWAQNMIKKLCRDNPTERLGYQKNGINDIKKHKWF
Kinase CG12069.AA Ciliate-E2 47-303 22 6e-75 255.3 In-house 1-365 (365) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YEIKATLGSGSFGKVQLVRERESGV-----------------------YYASKQLSKDQIVKTKQVSHVM----------SEKNVLRSMTFPNTVNLIAS
|..   .|.|.||.| ... .. .                        .|| |...|.||  .||. |.|           |||.|... .|| .... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YK--DFDSLYLVLPLIGGGELFTYHR-------------------KVRKFTEKQAR-------FYAAQVFLALEYLHHCS-LLYRDLKPENIMMDKNGYL
..  | ...|||. .. ||.|| | .                   ...........       ||.|.. |||||||     ..||.|||||..     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KVTDFGFAKKVET----------------------------------RTMTLCGTPEYLPPEIIQSKP---------YGTSVDWWAFGVLVFEFVAGHSP
|..|||..||. .                                   . |.||||.|..|||...|.         |....|.|..||. .|.. |  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FSAHNRDVMSMYNKICEADYKMP------------------SYFSGALRHLVDH----LLQVDLSKRFGNLINGNRDIKEHEWF
|          ...|.. ... |                   . |    .|       .||.| .||..    |  .|..|.||
F----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT----GWEQILNHPWF
Kinase CG12069.AA Ciliate-E2-Unclassified 47-303 26 1.4e-73 250.72 In-house 1-352 (352) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

YEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHV---------MSEKN-------------VLRSMTFPNTVNLIASYKDFDSLYLVL
|.|  ..|.|.||||....... . ||| |...| ||.| ||. ..         | .|.              |...  |. |...   .| . .|.|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

PLIGGGELFTYHRKVRK-----------------FTEKQAR-----FYAAQVFLALEYLHHCS-LLYRDLKPENIMMDKNG---YLKVTDFGFAKKVETR
 .. ||.|. |..|  |                 |||.||.     ||.||. ..||||||    ..||.|||||..|.||   |.|..|||..|| .. 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

------------------TMTLCGTPEYL----PPEIIQSKPYGTS----VDWWAFGVLVFEFVAGHSPFSAHNRDV--------------MSMYNKICE
                  . | ||||.|.    .||..|.. |..|    .|.|..||. .|.. |  ||.. |..               . .|..|..
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

ADYK--------MPSYFSGALRHLVD----HLLQVDLSKRFGNLINGNRDIKEHEWF
 ...         |   |    ...      .|.....||      .  .|..| ||
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-----TFEQILNHPWF
Kinase CG12069.AA TyrKc 47-303 21 3.8e-13 -10.16 SMART 1-280 (280) Show / Hide 
Range on Protein: 47-303
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YEIKATLGSGSFGKVQLVRERESGVYYASKQLSKDQIVKTKQVSHVMSEKNVLRSM--TFPNTVNLIASYKDF-------DSLYLVLPLIGGGELFTYHR
 . . .||.| ||.| . . .   .  | | | .|       .   |.| .....     || |.|..   .        . |..|. .  .| |  | |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KVRK-FTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKVETR-------TMTLC----GTPE-----YLPPEIIQSKPYG
| |. .. |.   .. |.    ||||.  .  |||   |.. ..|.  |..||| .....          .       |.        ..|| |. . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

TSVDWWAFGVLVFEFVA-GHSPFSA------HNRDVMSMYNKICEADYKMPSY-------FSGALRHLVDHLLQVDLSKR--FGNLINGNRDIKEHEWF
|  | |.|||. .|    | .| .        |..|.  | |  .   ..|..        . ..  .     . | ..|  | ..         || |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE-YVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---------HECF
Kinase CG12069.AA S_TK_X 304-356 18 2e-06 28.62 SMART 1-79 (79) Show / Hide 
Range on Protein: 304-356
Range on HMM: 1-79/79
Sequence Identity: 18% (15 aa)

KDVEWIPLLN--QTVNAPYVPNIS----NPEDISNFDKVSDKPRPKAKTMR---------------------HEEAFADF
... |  |.|  ... .|..|.|.    .|.|.||||.  ..  |.  |.                       .. ...|
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase CG12069.AA Pkinase_Tyr 47-264 24 1.4e-05 19.57 Pfam 1-236 (270) Show / Hide 
Range on Protein: 47-264
Range on HMM: 1-236/270
Sequence Identity: 24% (60 aa)

YEIKATLGSGSFGKVQLVRER----ESGVYYASKQLSKDQIVKTKQ--VSHVMSEKNVLRSM-TFPNTVNLIASYK-DFDS--LYLVLPLIGGGELFTYH
 ..  .||.|.||.| . . .    . ..  | | | |.     .|      |.| ......   || |.|..    . ..  .|.|...  .| | .| 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

RK----VRKFTEKQARFYAAQVFLALEYLHHCSLLYRDLKPENIMMDKNGYLKVTDFGFAKKV-------ETRTMTLCGTPEYLPPEIIQSKPYGTSVDW
||     ...| |.   ...|.  ..|||.   .  |||   |.. ..|.  |..||| |. .        .|. .       ..|| |. . . |  | 
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDV

WAFGVLVFEFVA-GHSP-FSAHNRDVMSMYNKICEADYKMP
|.|||| .| .  | .| .     .   .|..| |  | ||
WSFGVLMWEIFTYGEQPTYPGM--SNEEVYEYIYEDGYRMP