PKCdelta

Species: Fruit Fly
Alias: PKCdelta, CG10524, SFO074, PKCd, Protein kinase C delta
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 11A10--11,

Classification

Group: AGC
Family: PKC
Subfamily: PKCd

Sequence

Name Sequence Type Origin Length Description Download
PKCdelta.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 259 Kinase domain by global Sugen HMM Fasta, JSON
PKCdelta.AA Protein Various 515 None Fasta, JSON
PKCdelta.NA RNA None 1548 None Fasta, JSON

Protein domain

Protein domains of PKCdelta.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
C1_1 PKCdelta.AA C1_1 17-69 40 1e-18 72.38 Pfam 1-55 (55) Show / Hide
Range on Protein: 17-69
Range on HMM: 1-55/55
Sequence Identity: 40% (22 aa)

HRFVAK-FFRQPTFCAFCNLFLWG-FGKQGYQCIICQTVVHKKCHDKLLGKCSGS
|..|.. .|.|||||. |. |.|| .|.||..|  |. ..|..|| |.  .| ..
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN

C1 PKCdelta.AA C1 17-66 35 7.9e-16 59.82 SMART 1-61 (61) Show / Hide
Range on Protein: 17-66
Range on HMM: 1-61/61
Sequence Identity: 35% (22 aa)

HRFVAKFFRQPTFCAFCNLFLWGFGKQ-----GYQCIICQTVVHKKCHDKLLG-------KC
|..... | .||.|. |. ..||. ||     ||.|. |. ..|||||||..         |
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC

C1_1 PKCdelta.AA C1_1 89-141 41 9.8e-21 79.77 Pfam 1-55 (55) Show / Hide
Range on Protein: 89-141
Range on HMM: 1-55/55
Sequence Identity: 41% (23 aa)

HRFKPH-TFMSPTFCDHCGSLM-GGFFIQGLKCEECDVNCHKKCERLTANLCGVN
|....| .| .||||.|||... |... ||.||..| .|||..| .. ...|| |
HHWVHHWNFKQPTFCCHCGEFCWGWLGHQGWKCQWCHYNCHHRCHMKVPPECGCN

C1 PKCdelta.AA C1 89-138 30 8.6e-18 66.35 SMART 1-61 (61) Show / Hide
Range on Protein: 89-138
Range on HMM: 1-61/61
Sequence Identity: 30% (19 aa)

HRFKPHTFMSPTFCDHCGSLMGGFF-----IQGLKCEECDVNCHKKCERLTAN-------LC
|... ..| .||.|.||.....|.|     .||..|..|...||||| .  ..        |
HHWHWWRF-KPTYCCHCRKMIWGMFKQHWKMQGYRCSWCKYKCHKKCHDKVPQQSHQDGWMC

Kinase PKCdelta.AA PKC 187-445 61 1.4e-200 656.06 In-house 1-262 (262) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-262/262
Sequence Identity: 61% (162 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE
|.|| ||||||||||.|||...|..|||||.|||||...||||..|..|..||||..|||.|.||.|.|||...|||||||.||||||||||...||.||
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF
.||||.||||..|.|||.||||||||||||||||.|||..|||||||| ... ..|...|||||||.||||.....|...||||.||||.|||..|||||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSP---AGDIADHIFF
.|.||||||.||... |..|...| ||..|.||...|...||.|.....   ..|| .| ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF

Kinase PKCdelta.AA Delta 187-445 72 6.1e-186 624.01 In-house 1-259 (259) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-259/259
Sequence Identity: 72% (189 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE
|||..||||||||||.||||.....||||||||||||||||||..|..||.||||...||.||||||||||..|||||||||||||||.|||...||.|.
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLALAWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFDEK

RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF
|||||..|||.||.||||||||||||||||||||..||..|||||||| ..|..|.|..|||||||.|||||||.|||..|||||||||.||||||||||
RARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF

SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF
.|.|||||||||||..||.|..|..||...||.|.|.|..||.|.||.|.|||..|.||
HGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF

Kinase PKCdelta.AA AGC 187-445 31 1e-173 453.65 In-house 1-395 (395) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-395/395
Sequence Identity: 31% (125 aa)

FHFLAVLGKGSFGKVLLAELR------DTTYYYAIKCLKKDV-VLEDD--DVDSTLIE------------RKVLALGTK---------HPYLCH-LFCTF
|.|| |.|||||||| |.. .      ||  |||.|.|||.. .....  .|. |..|            |..|..  .         ||.... |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTESH--LFFVMEYLN---------GG-DLMFHIQ---ESGRFSEERARFYGAE-------IISGLKFLHK-KGIIYRD-LKLDNVLLDYEGHVRIADFG
|...|  |.|||||..         || .|..|.|    .|||.||||||| ||       |...| .||. .|||.|| ||..|.||| .||....|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

MCKLQIYLD--------------------------------------------------KTADSFCG--TPDYMAPEIIKGEKYNQNVDWWS--FGVLLY
.||  .  .                                                  ... .|||  ||.||||||.    |.. .||||  .|.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLIGQSPFSGC----------DEDELFWSIC------NEIPWFP----------VYISAEATGILKGLLEKDYTKRIGSQYSP-----AGDIADHIFF
|||.|..||.|           ...|.| .|.      |. . ||          ...| ||  ..|.||.|| .||.|.. .      | .| .| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase PKCdelta.AA Alpha 187-445 59 6.7e-139 467.74 In-house 1-259 (259) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-259/259
Sequence Identity: 59% (153 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE
| || ||||||||||.||| . |   |||| |||||.  ||||. |..|..||||. | |.|  .  .|||   |.||||| ||||||.|||  |.| | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF
 | || |||  || |||.|||||||||||||.|| |||..|||||||| ..  |.|   |||||||.|||||  . |   ||||.||||||||. || ||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF
 | |||||| .| .  . .|  .| ||  | ||.| |   || |.  .   ||  | ||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF

Kinase PKCdelta.AA Eta 187-445 55 3.2e-132 445.56 In-house 1-261 (261) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-261/261
Sequence Identity: 55% (144 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE
|.|. ||||||||||.|||...|   |||| |||||.. ||||. |. |...|.|  |||.|  |.|.|||.  ||||||| |||||||.|| . .| | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF
||||| ||... |.|||..|.|||||||||.||| ||| ..|||||||  |  ..|   |||||||.||||..  .|   |||| .|||.|||. ||.||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

SGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGD--IADHIFF
    ||.|| || ..   .||... ||..|||. . |  .||.|.  .  |.  |  | ||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF

Kinase PKCdelta.AA Akt 187-445 46 2.6e-119 383.05 In-house 1-264 (264) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-264/264
Sequence Identity: 46% (122 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYY-AIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSE
| || ||||||||||.|..  ||  .| |.| ||||. .. . |  |. ||..|   ..||..  |   |||. .|.|||.| |||.| .|.|  .||||
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQ-HCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

ERARFYGAEIISGLKFLHKKGIIYRD-LKLDNVLLDYEGHVRIADFGMCKLQ-IYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWS-FGVLLYEMLIG
.|||||.||||... .||.|.||||| ||. |.|.|..||....|||.||   |  . ....||||| |.||||..|  . . ||||. .|...|||. |
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

QSPFSGCDEDELFWSICNEIPWFP--VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF
. ||   | ...|  | |.   ||   .|| |.  ...|||.||..|| |. .. | .| .| .|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF

Kinase PKCdelta.AA SGK 187-445 38 6e-113 350.23 In-house 1-283 (283) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-283/283
Sequence Identity: 38% (109 aa)

FHFLAVLGKGSFGKVLLAELRDT------------------TYYYAIKCLKKDVVL-------EDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHL
|.|| |.||||||||....  |.                     ||.| |.|. ..           .  ...||.|.    ||| .  |   |||.  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGE
.|||.|.|||.. .|.|  ..|.| ||||| |||.. |  ||.. ||||||| .|.||| .||... ||| ||..|   .|  .||||| |.|||.....
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

KYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF
 .   ||||. | .||||..|  ||   .  ...  | |.   .| ..|..|  ...|||.|| .|| |.    ...| .|.||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF

Kinase PKCdelta.AA PKN 187-445 50 8.49999999999e-106 357.79 In-house 1-260 (260) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-260/260
Sequence Identity: 50% (131 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALG--TKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFS
|...||||.| ||||||.... |  ||||| |||  ..  |.|.| ..|.....    ..||.|  ||  ||||.| .|||||. ||||| || |   ||
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHED-VFS

EERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQI-YLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQ
| ||.|| | .. ||..||.. ||||||||||.||| ||.|.|||||.||  . | |.|.  |||||...|||..  . |   ||||  |||.||||.| 
EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTS-TFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGE

SPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF
.||.| ||.|.| .| |.   .| ..|.||  |.. || |   .|.|.    | ||  . ||
CPFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF

Kinase PKCdelta.AA Iota 187-445 47 7.69999999999e-103 343.43 In-house 1-271 (271) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-271/271
Sequence Identity: 47% (129 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEE
|. . |.|.||. |||..|.. |   ||.| .||..| .|.|.|    |..|      ||.|  |   ||||| ||||.|. ||||||||.|   .  ||
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLPEE

RARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPF
 |||| |||.  |.|||..||||||||||||||| |||... |.||||  |    |   ||||| |.||||..|| |.  ||||  |||..||. | |||
HARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPF

SGCD---------EDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSP---AGDIADHIFF
             || ||  |       |  .|  |...||| | || . |.| .        || .| ||
DIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF

Kinase PKCdelta.AA RSK 190-445 38 7e-102 344.78 In-house 1-278 (278) Show / Hide
Range on Protein: 190-445
Range on HMM: 1-278/278
Sequence Identity: 38% (107 aa)

LAVLGKGSFGKVLLAELR---DTTYYYAIKCLKKDVVLEDD-DVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGR---
| |||.|..||| |       ||  .|| | ||| ..   . |.  |. ||..|.. ..|| ...|. .||||..|. .|||..||.|  |.|. ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDY---EGHVRIADFGMCKL-QIYLDKTADSFCGTPDYMAPEIIK---GEK-YNQNVDWWSFGV
|||..|.|| |||.. ...||..|||.||||..|.|.|    |||... ||| ||.  .   . ...||.| .|||||..|   ... .....||||.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYEMLIGQSPFSG---CDEDELFWSICNEI--PWFP--VYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF
|.|||| |..|| |    . .|..  |..    . .|   |.|.||  .....|..|  ||.|.  . | .| .| .|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase PKCdelta.AA S_TKc 187-445 35 2e-96 327.6 SMART 1-231 (231) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-231/231
Sequence Identity: 35% (96 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNG--GDLMFHIQESGR--
...| ..|||.|||| ..  ..|  ..|||..|          .... |...|    .||....|. .||. .||..||||..|  |||. .|.. ||  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----FSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQ-NVDWWSFGVLLY
    |.| .|||| ..|...|...|..|||.|||| .|.|||   |. |.|||....        ..|||||.|||||..   .|.   .||||.|..||
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPA--GDIADHIFF
||| |. ||.  .....|  |.          | ||  .....|.|| .||..     .   ||. | .|
EMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase PKCdelta.AA Pkinase 187-445 32 4.3e-85 293.81 Pfam 1-293 (293) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-293/293
Sequence Identity: 32% (97 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTL-IERKVLALGTKHPYLCHLFCTFQTESHLFFVMEYLNGG----DLMFHIQ--E
.|.. ..|.||||.| ..  ..|   .|.|..||.   .. |.  ..  | ....   .||. . |...|....|. .||||..||    ||. .|.  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

SGRF--SEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHV----RIADFGMCKLQ-IYLDKTADSFCGTPDYMAPEIIK-GEKYNQNVDWWS
.|.|  ||. ..||  .|..||...|..|||.||||..|.|.| .||.    .|.||| .|.  .  .  ...|||||.|||||.|. |..| . ||.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

FGVLLYEMLIGQSPFSGC----DEDELFWSICNEIP-------WFPVYIS-----------------AEATGILKGLLEKDYTKRIGSQYSPAGDIADHI
.|..||||| |. ||.|.    . ..  . ||.  .       . .  ||                  |.  ..|..|.|| .||..     | .|  | 
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHP

FF
.|
WF

Kinase PKCdelta.AA S_TK_X 446-509 41 7.5e-24 86.48 SMART 1-79 (79) Show / Hide
Range on Protein: 446-509
Range on HMM: 1-79/79
Sequence Identity: 41% (33 aa)

RPIDWGLLEK--RQIEPPFKPQVK----HPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQ---------FHGFTYTN
| |||  |..  ..|||||||..|    .| || .||  ||.| ..|||.|. ...||.|..         | |||| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF

Kinase PKCdelta.AA Pkinase_C 465-511 51 8.9e-20 72.8 Pfam 1-46 (46) Show / Hide
Range on Protein: 465-511
Range on HMM: 1-46/46
Sequence Identity: 51% (24 aa)

QVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGFTYTNPH
|||.|.||..||  ||.|....|| |.. . |.|| .|.||||.|| 
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD

Kinase PKCdelta.AA TyrKc 187-445 24 7.6e-15 17.3 SMART 1-280 (280) Show / Hide
Range on Protein: 187-445
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

FHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALG-TKHPYLCHLF--CTFQTE-----SHLFFVMEYLNGGDLMFHIQ
 ... .|| | ||.| .....   .  |.|.||.|       .   . | ...     .|| .  |.  || | .       |. ||||  .|||  ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

ESGR-FSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLD----KTADSFC-----GTPD-----YMAPEIIKGEKY
.... .. .    .   | .|  .||.|..| |||   |.|.. ...|.|.|||...  || |       |        |. .      |||| |.  |.
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRD-IYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

NQNVDWWSFGVLLYEML-IGQSPFSG-----CDEDELFWSICNE-IPWFPVY--------ISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFF
.   | |||||...|..  ||.| .|     .. .|..  . .   .  | .         ..|   | |   . |  .|   .         | .|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-------HECF

Kinase PKCdelta.AA Pkinase_Tyr 353-398 39 5.8e-07 24.21 Pfam 181-228 (270) Show / Hide
Range on Protein: 353-398
Range on HMM: 181-228/270
Sequence Identity: 39% (19 aa)

MAPEIIKGEKYNQNVDWWSFGVLLYEMLI-GQSP-FSGCDEDELFWSI
|||| |.  |..   | ||||||..|..  |..| . |..  |..  |
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI

Kinase PKCdelta.AA Pkinase_Tyr 253-335 29 9.4e-07 23.5 Pfam 73-160 (270) Show / Hide
Range on Protein: 253-335
Range on HMM: 73-160/270
Sequence Identity: 29% (26 aa)

CTFQTES-HLFFVMEYLNGGDLMFHIQE----SGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKL
|| | |. ... ||||  .|||  . ..     .... ..   . ..| .|. .|. |..| |||   |.|.. ...|.|.|||....
CTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARD

Kinase PKCdelta.AA Pkinase_Tyr 187-221 30 4.4e-05 17.85 Pfam 1-39 (270) Show / Hide
Range on Protein: 187-221
Range on HMM: 1-39/270
Sequence Identity: 30% (12 aa)

FHFLAVLGKGSFGKVLLAELR----DTTYYYAIKCLKKD
 .|. .||.|.||.| .....    .|..  |.|.|| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEG