Gene CG2049 (Fruit Fly)

CG2049

Species: Fruit Fly
Alias: CG2055, CG2049, CT6660, PRK2, CT6637, SFO010
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 45C1--5,

Classification

Group: AGC
Family: PKN

Sequence

Name Sequence Type Origin Length Description Download
CG2049.AA Protein Various 1501 None Fasta, JSON
CG2049.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 260 Kinase domain by global Sugen HMM Fasta, JSON

Protein domain

Protein domains of CG2049.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HR1 CG2049.AA HR1 134-201 22 2e-14 54.83 Pfam 1-74 (74) Show / Hide 
Range on Protein: 134-201
Range on HMM: 1-74/74
Sequence Identity: 22% (17 aa)

EIKEAIRREIRKELKIKEGAEKLREV---AKDRRS----LSDVAVLVKKSKSKLAELKSELQELESQILLTSANT
. ....|..|..|.|||||||..|..   ..|...    .....   . |..|...|...|..|...    .  .
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 CG2049.AA HR1 248-318 33 2.1e-16 61.93 Pfam 1-74 (74) Show / Hide 
Range on Protein: 248-318
Range on HMM: 1-74/74
Sequence Identity: 33% (25 aa)

KVLASLEKQLQIEMKVKTGAENMIQSL--GIGCDK--KLLAEAHQMLADSKAKIEFLRLRIIKVKQNREQADRLK
..|..|.|....|||.| |||||.. .    .  |  |......||| .|. |||.|| .. |..|  .. .   
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKHRKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
HR1 CG2049.AA HR1 348-421 27 3.5e-22 82.68 Pfam 1-74 (74) Show / Hide 
Range on Protein: 348-421
Range on HMM: 1-74/74
Sequence Identity: 27% (21 aa)

ERIEELRHRLRIEAAVVDGAKNVIRTL--QTANRAPDKKALQEAHGRLSESSRKLDLLRYSLDLRRQELPADSPAA
.|...||.....| .. .||.|..| .  .|.|... .|..|.....|.||..|...|| .|  ..|...  .|..
QRLQQLRKKIEREMKIKEGAENMRRAYQMTTDNKKH-RKVRQQCQQMLRESNQKIEYLRMQLEKLQQRHQD-HPPN
C2_PKD CG2049.AA C2_PKD 555-646 20 1.9e-08 26.32 In-house 67-181 (183) Show / Hide 
Range on Protein: 555-646
Range on HMM: 67-181/183
Sequence Identity: 20% (24 aa)

WDQRFSIDLDRSRELEIGVYWRDW---RSLCAVKVLRLEEFID-----DVRHGMALQLEPQGLLFAEVKFLNPMISQKPKL---------------RRQR
|.. |  .....|...| .. ..    .. .|    .||. |      .   .. . ||||| ... .| .|.  . |...                |||
WNKCFDHHVYEGRHIQIVCMHNAIMPPNKMVAECTMKLEDCIEMCKTNSGITHIWINLEPQGKVHVQIKWFNEDTDHKHHCDMIHPVPVLKMMKEFKRQR

MIFNRQQAKNISRAK
  ||| ..  . .||
PGFNRRRGNAMRHAK
C2 CG2049.AA C2 473-601 8 2e-06 28.67 SMART 1-92 (92) Show / Hide 
Range on Protein: 473-601
Range on HMM: 1-92/92
Sequence Identity: 8% (12 aa)

KLEVRLLGCQDLLEDVPGRSRRDKDNNSSPGDLRSFVKGVTSRSSSKSYSVKDETSIEIMAVIKLDNITVGQTSWKQCS----QQAWDQ---RFSIDLDR
.|.|... ...|                                                ....       .|......       |..    | .|...
TLTVHIIEARNLP--------------------------------------------DPYVKVY-------KTKVVKNTLSGFNPVWNEWMETFYFDVHP

SRELEIGVYWRDWRSLCAVKVLR-------------LEEFIDDVRHGMA
 . |.. |. .  . .  . . .             |.. .   || . 
-Q-LRFEVWDH--DFIGHCCIPPNNPHWHQWDGCIHLSDIL-GYRH-WW
Kinase CG2049.AA PKN 1174-1433 85 1.2e-205 689.5 In-house 1-260 (260) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-260/260
Sequence Identity: 85% (222 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFLE
||...||||||||||.|||......|||||||||.||.||||||||..|||||||.|.|||||||||..|||||.|||||||||.|||||||||.||| |
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHEDVFSE

PRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESP
|||.|||||||||||||||.|||||||||||||||||||||||||||||||||.||||.|||||||||||||||.||||||||||||||||.||||||.|
PRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGECP

FPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFF
|||||||||||.||||.||||||||.||||.||||||||||||||..||||||.|.|.||
FPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF
Kinase CG2049.AA AGC 1174-1433 32 8.60000000001e-177 461.77 In-house 1-395 (395) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-395/395
Sequence Identity: 32% (130 aa)

FRLLSVLGRGHFGKVILSQLR------SNNQYYAIKALKKGD-IIARD--EVESLLSE------------KRIFEVANAMR-------HPFLVN-LYSCF
|..| |.|.|.||||.| . .      ....|||.| ||| . |. ..  .||  ..|            ..|.| .|  .       |||.|. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTEQH--VCFVMEYAA---------GG-DLMMHIHTD----VFLEPRAVFYAAC-------VVLGLQYLHE-NKIIYRD-LKLDNLLLDTEGYVKIADFG
|...|  ..|||||.          || .|..|.. .    .| |.|| ||||.       .||.|.|||. ..||.|| ||..|.||| .|..|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKEGMGFG--------------------------------------------------DRTGTFCG--TPEFLAPEVLTETSYTRAVDWWG--LGVLIF
||||||. |                                                  ||| ||||  |||..|||.|    |..|.|||.  ||.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLVGESPFPGD----------DEEEVFDSIV------NDEVRYP----------RFLSLEAIAVMRRLLRKNPERRLGSSERD-----AEDVKKQAFF
|||.| .|| ||          ...|.|..|       |..|..|          |..| ||   ...|| |.||.|||. ..|     ||..|.  .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase CG2049.AA PKC 1174-1433 52 1.3e-148 484.99 In-house 1-262 (262) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-262/262
Sequence Identity: 52% (138 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTD-VFL
|..| |||.| ||||.|. .. ...|||||.|||  ||  | ||. . |||... |.   ||||..|..||||. .  |||||  ||||| ||     | 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWK--HPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFK

EPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGES
|..|.|||| ....||.|||. |||||||||| ||| || .||||||.|||.|  ||.| ||||||...|||.| .  |. .|||| .||| .||..| |
EEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQS

PFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERD---AEDVKKQAFF
|| |.||.|.|.|| .|...||| || || ...  .. ||||.|||. ...   ..|... .||
PFHGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase CG2049.AA Akt 1174-1433 43 5.4e-116 372.29 In-house 1-264 (264) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-264/264
Sequence Identity: 43% (116 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYY-AIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTD-VF
|..| |||.| ||||.| .  .....| |.|.|||  ||....||  . |..| .  |   |||.|||.  |||... .|||.|. ||.|  |.. . .|
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN---HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRF

LEPRAVFYAACVVLGLQYLHENKIIYRD-LKLDNLLLDTEGYVKIADFGLCKEG-MGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWG-LGVLIFEML
 |.|| ||.| ..|....||.. ||||| ||. |.|.| .|.....|||||||. .  .|.| ||||||| ||||.|  . .|.|||||| ||....||.
SEDRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMM

VGESPFPGDDEEEVFDSIVNDEVRYP--RFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFF
 |  ||  .| .. |. | | .|..|  ...| |.    ..|| |.|..|||. . ||...|   .|
CGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase CG2049.AA Alpha 1174-1433 49 7.29999999999e-116 391.23 In-house 1-259 (259) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-259/259
Sequence Identity: 49% (130 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHI-HTDVFL
|  |.|||.| ||||.|.  .  .  |||| |||  ||  | ||  . |||.   |   . |||| . |||||     |||||  ||||| ||     | 
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRV--LALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFK

EPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGES
|| |||||| .  || .|||  |||||||||| .|| || .||||||.|||.|  .. | ||||||...|||.     | ..||||  ||| .||..|  
EPHAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQP

PFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFF
|| |.||.|.| .| . .| ||. .| ||... . .| |.| .|||.   . .|... .||
PFDGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase CG2049.AA Delta 1174-1433 49 9.20000000001e-115 387.57 In-house 1-259 (259) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-259/259
Sequence Identity: 49% (130 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHI-HTDVFL
| .. |||.| ||||.|. |.  |.|||||.|||  ..  |.||. . |.|.  .  |..||||  |.  |||..|. |||||  ||||| || ..  | 
FHFHKVLGKGSFGKVMLAELKGKNKYYAIKCLKKDVVLEDDDVECTMVERRVLAL--AWEHPFLCHLFCTFQTKEHLFFVMEYLNGGDLMYHIQQCHRFD

EPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGES
| || |||. ...|||.||.. ||||||||||.||| .| .||||||.||| |    .. ||||||...|||..    |...||||  |||..|||.| |
EKRARFYACEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMCKENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQS

PFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFF
|| |.||.|.|.||.||.  |||... ||  ....|. ..||.|||. .  . |...  ||
PFHGEDEDELFWSICNDRPWYPRWITKEAKDCLKKLFERDPEKRLGVQYCPKGDIRQHCFF
Kinase CG2049.AA Eta 1174-1433 49 3.1e-114 385.83 In-house 1-261 (261) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-261/261
Sequence Identity: 49% (129 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHI-HTDVFL
|  . |||.| ||||.| ...  .. |||| |||  ||  |.||  . ||||  .|.  .|||| .|..||||.  . |||||  ||||| .| ..  | 
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLAR--KHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFD

EPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGES
|||| |||| |.. |..||.. .|||||||||.||| ||  |.||||.||||.  |  | ||||||...|||.| |  |  .|||| .|||..||. |..
EPRARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQP

PFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSE--RDAEDVKKQAFF
||  | |...|.||..|.| || .|. ||.....  . |||..|||. .   . ..... .||
PFEADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase CG2049.AA SGK 1174-1433 39 1.1e-104 324.29 In-house 1-283 (283) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-283/283
Sequence Identity: 39% (114 aa)

FRLLSVLGRGHFGKVILSQLRSN------------------NQYYAIKALKKGDII-------ARDEVESLLSEK-RIFEVANAMRHPFLVNLYSCFQTE
|..|.|.| | |||| . .  .                    . ||.| |.|  ||       .. |.   ..|.  |    . |.|||.|||   |||.
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVIL---KNMKHPFIVNLHYAFQTK

QHVCFVMEYAAGGDLMMHIH-TDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVL
.   |||.|. ||..  |.     |.|.|| |||| .|. | |||. .||||||| .|.||| .|.... ||||||||.   | | ||||||| ||||||
WKLYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVL

TETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAFF
    . |.|||| || . .||..|  ||   . .. .| | | . . |.. | .|   .  || |.|. ||| . ||....|.  ||
RKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLG-TKRDFMEIKNHPFF
Kinase CG2049.AA S_TKc 1174-1433 34 2.2e-96 327.42 SMART 1-231 (231) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-231/231
Sequence Identity: 34% (93 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAG--GDLMMHIHTDV-
...| ..|.| |||| . . .. ....||| .|          |....| .| .     .||..|.|| .||. .|...||||. |  |||. .|.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------FLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTR-AVDWWGLGVL
      | | .| ||.. ....|.|.|...||.|||| .|.|||.   .||.||||...         ||||||...|||||   .|.. ..||| .|..
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

IFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERDA--EDVKKQAFF
..|||.|. |||  .....|. |.          | ||.  .|..|.|.||.|..  |  .  .|.|.  .|
LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG2049.AA AktR 1174-1433 40 1.1e-95 324.23 In-house 1-268 (268) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-268/268
Sequence Identity: 40% (108 aa)

FRLLSVLGRGHFGKVILSQLR-SNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIH-TDVF
|... .||.| ||||.| | .  |...||.| .|| .|| |   . .. |. | |  . ..|||.|.|. ||||. .  |.||| .||.|  |.     |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIME--MCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKF

LEPRAVFYAACVVLGLQYLHEN-KIIYRDLKLDNLLLDTEGYVKIADFGLCK-EGMG-FGDRTGTFCGTPEFLAPEVLTE-TSYTRAVDWWGLGVLIFEM
 | .| ||.| ..|.|.|||.. .||||||| .|.||| .|.|||.|||| | ..|    ... .|||||| .|||..|.   ....|||| .|..|.||
SEEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

LVGESPFPGDDEEEVFDSIVNDE---VRYPRFLSLEAIAVMR-RLLRKNPERRLGSSERDAEDVKKQAFF
..|  ||  .. .. |..| . .   . ||  .| ..      .|| |||. |||..  ..|..|.  .|
VTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase CG2049.AA Iota 1174-1433 44 1.8e-93 311.67 In-house 1-271 (271) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-271/271
Sequence Identity: 44% (122 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHIHTDVFL-
|.|. |.||| . ||.. ....... ||.| .||  .   ....    || .|| |    ||||| | ||||||  . ||.|.  ||||| |.     | 
FELIRVIGRGSYAKVLMVEHKKTRRIYAMKVIKKEMVNDDEDIDWVQTEKHVFEQASN--HPFLVGLHSCFQTESRLFFVIEFVNGGDLMFHMQRQRKLP

EPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGES
|  | ||.| ..| |..|||  |||||||||| ||| || .|. |.|.||||.  || | |||||| ..|||.|    |  .|||| ||||.|||. | |
EEHARFYSAEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRS

PFP--G-------DDEEEVFDSIVNDEVRYPRFLSLEAIAVMRRLLRKNPERRLGSSERD---AEDVKKQAFF
||   |         |. .|  |.  ..| ||.||  |  |..  | |.|. |||         .|.|. .||
PFDIVGNMDNPDQNTEDYLFQVILEKQIRIPRSLSVRAAHVLKGFLNKDPKERLGCHPQTNEGFMDIKEHPFF
Kinase CG2049.AA Pkinase 1174-1433 28 3.1e-82 284.3 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1174-1433
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLL-SEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGG----DLMMHIH-
.......|.| ||.| . . ..... .|.| .|| ..    ... .. || .|    |   ||. | || .|....|...||||. ||    ||. .|. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

--TDVF--LEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYV----KIADFGLCKEG-MGFGDRTGTFCGTPEFLAPEVLT-ETSYTRAVDW
    .|   |  . ||.  .. ||.|.|...||.||||..|.|.| .|..    ||.||||.|      .  . ||||||...||||.   . |...||.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WGLGVLIFEMLVGESPFPGD------DEEEVFDSIVNDEVRYPRFLS---------------------LEAIAVMRRLLRKNPERRLGSSERDAEDVKKQ
|..|....||| |. ||||.      |. .... |   ....... .                      |.. .....|.|.|..|..     ||.... 
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQH

AFF
 .|
PWF
Kinase CG2049.AA S_TK_X 1434-1498 32 2.4e-19 71.5 SMART 1-79 (79) Show / Hide 
Range on Protein: 1434-1498
Range on HMM: 1-79/79
Sequence Identity: 32% (26 aa)

RSIVWDDLLL--RKVKPPFVPTIN----HLEDVSNFDEEFTSEKAQLTPPKE---PRHLTEE-----EQLLFQDFSYTA
|.| ||.|.   ....|||.|.|.    . .|.||||.|||.|.. |||. .   ...  .|     . . | .|.| .
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase CG2049.AA Pkinase_Tyr 1174-1322 26 2.7e-17 59.21 Pfam 1-159 (270) Show / Hide 
Range on Protein: 1174-1322
Range on HMM: 1-159/270
Sequence Identity: 26% (44 aa)

FRLLSVLGRGHFGKVILSQLR----SNNQYYAIKALKKGDIIARDE---VESLLSEKRIFEVANAM-RHPFLVNLYSCFQ-TEQH--VCFVMEYAAGGDL
 ... .||.|.||.| .  ..    ....  |.| ||     | .|    |....| .|      . .|| .|.|| .    ...  .. ||||...|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMK---QLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

--MMHIH---TDVFLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCK
    . |    . .  .. . ... .  |..||.....| |||   | |.. .. |||.||||..
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase CG2049.AA Pkinase_C 1453-1500 33 3.1e-17 63.87 Pfam 1-46 (46) Show / Hide 
Range on Protein: 1453-1500
Range on HMM: 1-46/46
Sequence Identity: 33% (16 aa)

TINHLEDVSNFDEEFTSEKAQLTPPKEPRHLTEEEQLLFQDFSYTAEW
.... .|.||||.|||.|....||  ..| .....|..|..|.|....
QVKSPTDTSNFDPEFTDEPPMDTP-PDWR-MSSGDQEPFRGFTYVNPD
Kinase CG2049.AA TyrKc 1174-1432 22 5.7e-17 51.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 1174-1432
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

FRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGDIIARDEVESLLSEKRIFEVANAM--RHPFLVNLYSCFQTE-------QHVCFVMEYAAGGDLMM
 .|. .||.|.||.| . ...   .  |.| ||..       .| ...| ||         .|| .|.|| .  ..       . .. ||||...|||  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMC---KLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

HIHTDV--FLEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGF---GDRTGTFCG----TPEF------LAPEVLTET
...     .  .  . ..  .  | .|||....| |||   | |.. .. |||.||||....      | .. .          .      .|||.. . 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

SYTRAVDWWGLGVLIFEML-VGESPFPG-----DDEEEVFDSIVNDEVRYPRFL---------SLEAIAVMRRLLRKNPERRLGSSERDAEDVKKQAF
 .| . | |  ||...|..  |..| ||      . .||.  . . . . .            . |   .|..  . .|| |   ||       .. |
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI------HECF
Kinase CG2049.AA Pkinase_Tyr 1341-1376 39 0.003364 11.46 Pfam 181-218 (270) Show / Hide 
Range on Protein: 1341-1376
Range on HMM: 181-218/270
Sequence Identity: 39% (15 aa)

LAPEVLTETSYTRAVDWWGLGVLIFEMLV-GESP-FPG
.|||.. .  .| . | |  |||..|..  ||.| .||
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPG