Gene drl (Fruit Fly)
drl
Sequence
Protein domains of drl.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| WIF | drl.AA | WIF | 21-157 | 50 | 2.6e-88 | 300.61 | SMART | 1-146 (146) | Show / Hide |
Range on Protein: 21-157 Range on HMM: 1-146/146 Sequence Identity: 50% (74 aa) HLNIFLNLHEVLRLIGVSAELYYVREGAINDYALNF------AVPVPANISDVTFTWQSLVD-HPLPYSINIATSDTEVLPRPILNISRIGDVPVEPQTW |.|...| ||..|||||.|||||||||.||.||.|| ..||||||....||||.... |...|.||....|.||.|.||.||...|.||...|.| HVNMWINKHEMRRLIGVDAELYYVREGHINHYAHNFRKAQQRMYPVPANIHYMHFTWQAVGQAHYVHYFINVQSDDQEVMPMPIVNIPHQGTVPHTLQVW GIALKCSGTRN--AEVTVTINVEVILDRATNNNTNLIFKRKKICLR ....||||.|. ||..||..|.|...|.|.|.|.|.|.|||||.. QVEYKCSGHRDGVAEFMVTMYVMVKYNRSTKNFTHLNFRRKKICYQ |
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| WIF | drl.AA | WIF | 24-155 | 45 | 3.8e-76 | 261.56 | Pfam | 1-145 (145) | Show / Hide |
Range on Protein: 24-155 Range on HMM: 1-145/145 Sequence Identity: 45% (66 aa) IFLNLHEVLRLIGVSAELYYVREGAINDYALN-----F------AVPVPANISDVTFTWQSLVDHPLPYSINI-ATSDTEVLPRPILNISRIGDVPVEPQ ...| |.| .|||||||.||...|..|.||.. | ..|||.|...|.||||||..|...|.... ..||.....||.||||..|.|| |.. MWINEHQVMMLIGVSAEIYYIHNGHVNHYAHDPNFSHFRKAQQRMPPVPSNVHYVNFTWQSLGKHKYHYNFQVLYSSDQQIMKRPTLNISHQGRVPHEAK TWGIALKCSGTRNAEVTVTINVEVILDRAT-NNNTNLIFKRKKIC .. |.|.|||.|....|.|.|.||...|.. ||||.|.||||||| EFSIDLPCSGNRSGQATFTVNLEVMHRRSKPNNNTPLRFKRKKIC |
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| Kinase | drl.AA | Ryk | 343-599 | 56 | 2.1e-218 | 697.63 | In-house | 1-292 (292) | Show / Hide |
Range on Protein: 343-599 Range on HMM: 1-292/292 Sequence Identity: 56% (164 aa) VRLSCLVQEGNFGRIYRGTYN------------------DCQEVLVKTVAQHASQLQVNLLLQESMMLYEAS-HPNVLSVLGIS--------IEDYATPF ...|||||||.|||||.|..| |||.|.||||..||||.||...||||..||..| |.|.|.||... |||...|| IQYSCLVQEGTFGRIYHGIWNQVDDVNNGDVDDEEDTFCDCQDVFVKTVKDHASQMQVHCMLQESCLLYGISPHQNILPVLHVCSFGRFDRPIEDHDPPF VLYAATGSVRNLKSFLQD-----PSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQ---LRVKLTDSALSRDLFPGDYNSLGDGEYR |.|.......|||.|||| |.......|.|.|.|..|..|.|.|||.|...|||||.||||||.| |.||..||||||||||.||..|||.|.| VCYPHMNNWGNLKQFLQDCRHDKPKCHQAISTHQLVHMAIQITMGMMHLHKHRIVHKDIATRNCVIDEQNGRLQVKICDSALSRDLFPMDYHCLGDNENR PIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICL |.||.|||.||..||...||||||||.|||..|||..||.||||.||.|||||||||.|||||||||||.||.||..||.|||.|.||..|| PVKWMSLESLQHKHYSHASDVWSFGVTMWELMTLGQMPYMEIDPFEMYHYLKDGYRLQQPFNCPDELFTVMACCWHCMPEERPTFQQLVQCL |
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| Kinase | drl.AA | TyrKc | 343-599 | 30 | 1.1e-96 | 328.45 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 343-599
Range on HMM: 1-280/280
Sequence Identity: 30% (88 aa)
VRLSCLVQEGNFGRIYRGTYNDCQEVLVKTVAQHASQLQVNLLLQESMMLYEA--SHPNVLSVLGISIED-----YATPFVLYAATGSVRNLKSFLQDPS
..| ||.||..|.||.. ..| ||.. .| . ...| .. . .|||.. .|. ... |. | . . .||..|...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR
YARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPG-------DYNSLG---DGEY-RPIKWLSLEALQKSHYNE
... . . . | | ||.|| ...|| |.||||| ......|| .| ||||. . || . .| . ||.|...|..... ...
PK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT
GSDVWSFGVLMWEMCTLGKLPYAE-----IDPYEMEHYLKDGYRLAQPFN--------CPDELFTIMAYCWASMPAERPSFSQLQICL
||||||||.|||..|.|. || . ....|. .|.|.|||. || | ||||...|| ||. |..||.||.. |.
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
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| Kinase | drl.AA | Pkinase_Tyr | 343-599 | 31 | 4.2e-96 | 326.11 | Pfam | 1-270 (270) | Show / Hide |
Range on Protein: 343-599 Range on HMM: 1-270/270 Sequence Identity: 31% (87 aa) VRLSCLVQEGNFGRIYRGTYN-----DCQEVLVKTVAQHASQLQ--VNLLLQESMMLYEA-SHPNVLSVLGISIEDYAT--PFVL--YAATGSVRNLKSF ... ||.||..|.||.. ....| ||.. ..|.. | ...| .. . .|||... .|. ... ... |.. | .|... ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG---DLLDY LQDP-SYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYN-SLGDGEYRPIKWLSLEALQKSHYNEGSDV |... . ...|. . . | | |..||.|.... || |.||||| ..... || .| |.||... || ..| ||||...|... . ... ||| LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDV WSFGVLMWEMCTLGKLP-YAEIDPYEMEHYL-KDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICL |||||||||..|.|. | |......|. .|. .||||...| |||||. ..| ||. |..||.||... .| WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | drl.AA | TK | 343-599 | 17 | 1.1e-74 | 249.64 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 343-599
Range on HMM: 1-486/486
Sequence Identity: 17% (85 aa)
VRLSCLVQEGNFG---RIYRGTYND--------------------------CQEVLVKTVAQ--HASQLQVNL--------------LLQESMMLYE--A
..| ||.|| ..|.|.... ...| ||.. ..|| . . ...| .|. .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
SHPNVLSVLG-ISIEDYATPFV-------LYAATGSVRN------LKSFLQDPSYARS------------------------------------------
|||... .| .. .. ..| .. . . . |...|.. . ..
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY
-------------------------------VTTIQTVLMGSQLAMAMEHLHNH------GVIHKDIAARNCVIDDQLR-----------VKLTDSA---
.|. | . | |.| .||.|| . ...| |.||||| ...... .|..|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR
-----LSRDLFPGDYNSLGD------------------------GEYRPIKWLSLEALQKSH---------YNEGSDVWSFGVLMWEMCTLG-KLPYAEI
|.||. ..|. . | ||.|.. |.|.. . . . ||||||||||||..|.| . .| ..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM
DP---------YEMEHYLKDG--------------YRLAQPFNCP--------------DELFTIMAYCWASMPAERPSFSQLQICL
. |. ||..| .|..|| .|| .|.. .| ||. |..||.||||. .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
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| Kinase | drl.AA | Met | 344-593 | 31 | 8.5e-61 | 197.94 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 344-593 Range on HMM: 1-271/271 Sequence Identity: 31% (86 aa) RLSCLVQEGNFGRIYRGTYND----CQEVLVKTVA--QHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYA-TPFVL--YAATGSVRNLKSFLQDP . . | || .|.|.| | . .|. .. | | .| . .|||||| .||.... | |. | . | ||.| .| HFDDVIGQGHFGCVYHGMYHDNDGNEHHCACKSLHGERITDIQHISQFLREGIMMKHFDHPNVLSLIGICLDPEGHMPWVVLPYMKHG---DLKTFIRNP SYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDL-FPGDYNSLGDGEY---RPIKWLSLEALQ--------KSH- . . . . . . | | |. .. .| | |.||| .| ..|| | |.||. | | . |.||. .| || . Q--NNPCVRDLIEFCHQVAKGMMYMASQKFVHRDLACRNCMLDEHFTVKVADFGLCRDMDYDKEYYSQMHHTHPARLPVKWMAPECLQQGVCLGCPTYRQ YNEGSDVWSFGVLMWEMCTLGKLPYAEIDP-YEMEHYLKDG--YRLAQPFNCPDELF-TIMAYCWASMPAERPSFS .. ||||||||.||| | | || ..|. |.|. | || || ||| | .| || . |..||.|| FTTKSDVWSFGVVMWELMTRGAPPYPHVDNWFDITHWLHQGETRRLPQPEYCPDHLYTDVMLCCWHANPEDRPQFS |
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| Kinase | drl.AA | TK-Unique | 451-599 | 37 | 6.9e-59 | 201.66 | In-house | 139-294 (294) | Show / Hide |
Range on Protein: 451-599 Range on HMM: 139-294/294 Sequence Identity: 37% (58 aa) QLAMAMEHLHN--HGVIHKDIAARNCVIDDQLRVKLTDSALSRDLF-PGDYNSLGDGEYRPIKWLSLEALQ--KSHY-NEGSDVWSFGVLMWEMCTLGKL |.|..||.|. ....|.|..|||. . . ...|..| ..||. .|.|.. . . ||.|...|.|. . .| .. ||||||||||||..|||. QIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGAC PYAEIDPYEMEHYLKDGYRLAQPFNC-PDELFTIMAYCWASMPAERPSFSQLQICL || .... ... ..||||. || .| ..|.. .| .|| . | |||||.|. | PYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL |
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| Kinase | drl.AA | UTK | 343-599 | 27 | 3.9e-52 | 176.66 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 343-599 Range on HMM: 1-296/296 Sequence Identity: 27% (82 aa) VRLSCLVQEGNFGRIYRGTYNDCQ------EVLVKTVAQHASQLQVNL----LLQESM---MLYEAS-HPNVLSVLGISIEDYATPFVLYAATGSVRNLK |.|. . .|.|| ........| | ||. ||. | .. |. |. . ||||| ..|. . . |. . .. .| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENG--DLR SFLQDPSYARS-----VTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQ-------LRVKLTDSA---LSRDLFP--------GDYNSLGDGE |.|.. . . .| | . | .. | .|..||..|..| |.||||| .... . .|. | .||.. ..| . .. SYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQ YR-PIKWLSLEALQKS-HYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDG--YRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICL | ||.| . ||| . .. . ||||||||..||..| |.|||... . | . .| ||...| ||......| ||.. |.|||.| .| . DRWPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM |
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| Kinase | drl.AA | KIN6 | 456-599 | 40 | 6.3e-49 | 159.73 | In-house | 157-305 (305) | Show / Hide |
Range on Protein: 456-599 Range on HMM: 157-305/305 Sequence Identity: 40% (61 aa) MEHLHNHGVIHKDIAARNCVIDDQLR---VKLTDSALSR--DLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEID || ||. . || |.|||| .. ..| | | | | . |.|.| | | ||||...|.|.. . ||||||||||.|| .|| ||.|. MEYLHSKNCIHRDLAARNVLVTEGCRMKTCKISDFGLCRYPYMDQFQYTSKG-GRYLPIKWMAPECLKHYEFSYKSDVWSFGVLMFEMFSLGDVPYPEMQ -PYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICL | || .. | |...| .||.| . || ||.. | .|| |... . RPTEMIEHHRSGRRPKHPKWCPEEIYDIMQSCWQEKPDDRPEFNEMRMQF |
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| Kinase | drl.AA | Axl | 452-597 | 43 | 2e-48 | 167.21 | In-house | 122-267 (267) | Show / Hide |
Range on Protein: 452-597 Range on HMM: 122-267/267 Sequence Identity: 43% (64 aa) LAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDP .|. || | |. ||.|.|||||.. ... | | ||. .. ||| | |.||. .|.| | ||||.||| |||. | |. ||. .. IACGMEYLSNRNFIHRDLAARNCMLREDMTVCVADFGLSKKIYSGDYYRQGCIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIMTRGQTPYPGVEN YEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQI || || .| || || .| |||. .| || | .|||||.|. HEMYDYLIHGHRLKQPEDCMDELYDLMYQCWEADPKDRPSFSVLRE |
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| Kinase | drl.AA | Abl | 343-599 | 30 | 4.7e-47 | 154.75 | In-house | 1-252 (252) | Show / Hide |
Range on Protein: 343-599 Range on HMM: 1-252/252 Sequence Identity: 30% (79 aa) VRLSCLVQEGNFGRIYRGTYNDCQE-VLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGSVRNLKSFLQDPSYARSVT . . . | .| .| | . . | |||. . ..|. |.| .. | |||. .||. . || . . || .| . . .... IMMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDT--MEVHEFLKEAAIMKEMKHPNLVQLLGVCTRE--PPFYIITEFMCYGNLLDYLRE-CDREELP TIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTL . . | .|.| .|. | .. ||.|.|||||.. .. ||. | |.| . .| | |||| |.| .. |||| ||||.||. | AVVLLYMATQIASGMSYLEKRHFIHRDLAARNCLVGEHHIVKVADFGLAR-MMKDDTYTAHAGAKFPIKWTAPESLAYNKFSSKSDVWAFGVLLWEIATY GKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICL | || || .. | | .|||. .| ||.. . .| || ...|||| .. . GMSPYPGIDLSHVYHKLEKGYRMERPEGCPPKVYELMRQCWQWSHTDRPSFKEIHHAM |
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| Kinase | drl.AA | Frk | 343-603 | 30 | 1.9e-46 | 158.88 | In-house | 1-260 (260) | Show / Hide |
Range on Protein: 343-603 Range on HMM: 1-260/260 Sequence Identity: 30% (81 aa) VRLSCLVQEGNFGRIYRGTYNDCQEVLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGSVRNLKSFLQ-DPSYARSVT ..| . | || .. | .| | |||. . . | .|.| .. . || .... . . | . . |. .|| |.. IQLIRRLGSGQFGEVWEGLWNNTTPVAVKTL--KPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVE--EPIYIITELMRHGSLQEYLQAINDKGRQCQ TIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDY--NSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMC | | | |.| | | .. ||.|.|||| ...... .|. | | | | . | |||| || . ... |||||||.|. |. MQQLVDMAAQVAAGMAYLESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEII TLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSEFH | |..||. . |. . .. |||. || ||| .|. || || | | .|| | || | .. TYGRMPYPGMTNAEVLQMVDHGYRMPQPPNCPQQLYEIMLECWHSDPMKRPTFETLQWKLEDYF |
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| Kinase | drl.AA | Src | 426-599 | 36 | 7.4e-42 | 139.97 | In-house | 80-255 (255) | Show / Hide |
Range on Protein: 426-599 Range on HMM: 80-255/255 Sequence Identity: 36% (64 aa) NLKSFLQDPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFP--GDYNSLGDGEYRPIKWLSLEALQKSHYN .| .|.. . |.. | . |. | | |. | .|| | |||| ..... .| | | | |. | . | |||| ||.. ... SLLDYLKKDGEGRHLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFT EGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFT-IMAYCWASMPAERPSFSQLQICL |||||||.|..|. | |. || . | .. |||. .| ||||||. || || . | .|| | || | IKSDVWSFGILLTEIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL |
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| Kinase | drl.AA | S_TKc | 343-606 | 17 | 3.1e-16 | 61.07 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 343-606 Range on HMM: 1-231/231 Sequence Identity: 17% (48 aa) VRLSCLVQEGNFGRIYRGTYND-CQEVLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGSVRNLKSFLQDPSYARS-- .. .. .| ||. |... .. ..| .| . . ...| .| . |||. ... . .|. . |.. .|...... . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -VTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNE-GSDVWSFGVLMWE . .. . |.. |.|..|.||.|| |. | .|. ..|..| |.| | . ... | | .|. .|.||.|....| PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE MCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQI--CLSEFHTQI |.. |. |. ....| . .. ..|. .. |. |..||. .. . | . MLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | drl.AA | TK-Unique | 343-410 | 23 | 2.3e-10 | 32.04 | In-house | 1-76 (294) | Show / Hide |
Range on Protein: 343-410 Range on HMM: 1-76/294 Sequence Identity: 23% (18 aa) VRLSCLVQEGNFGRIYRGTYND-------CQEVLVKTVAQHASQL-QVNLLLQESMMLYEASHPNVLSVLGISIED ... ...||.|| ..||.. . |.||.. .|... . ..| .|| . |||... ||..... LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKS |
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| Kinase | drl.AA | Pkinase | 515-595 | 16 | 1.1e-07 | 28.21 | Pfam | 181-287 (293) | Show / Hide |
Range on Protein: 515-595 Range on HMM: 181-287/293 Sequence Identity: 16% (18 aa) EALQ-KSHYNEGSDVWSFGVLMWEMCTLGKLPYAEI----DPYEMEHYLKDGYRLAQPFNCP-----------------------DELFTIMAYCWASMP | .. ..| .|.||.|....||.. |..|. . . ... . .. . .|..| .|. .. .|.. | EVIRGGQYYGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP AERPSFSQL ..||.. |. KKRPTAEQI |
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| Kinase | drl.AA | Pkinase | 343-486 | 17 | 6.3e-07 | 25.58 | Pfam | 1-155 (293) | Show / Hide |
Range on Protein: 343-486 Range on HMM: 1-155/293 Sequence Identity: 17% (28 aa) VRLSCLVQEGNFGRIYRGTYNDCQE-VLVKTVAQHASQLQV---NLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGS--VRNLKSFLQDPSY .. . .|.||. |... . .. | ||.. . .. ...|.| .. . .|||.. ... .. .|. . | | |..... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WR ARSV--TTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRV----KLTD ... . . . |.. ..|..|..|.|| |. |. ||.. . |..| HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICD |
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| Kinase | drl.AA | Axl | 343-409 | 27 | 0.000196 | 11.36 | In-house | 1-72 (267) | Show / Hide |
Range on Protein: 343-409 Range on HMM: 1-72/267 Sequence Identity: 27% (20 aa) VRLSCLVQEGNFGRIYRGTYN--D--CQEVLVKTV-AQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIE . | .. || || . | . | . | ||.. .. .| .. |.| . | .||||. ..|..|. FVLGKMLGEGEFGSVMEGQLKQEDGSFVKVAVKMMKIDICTQSEIEEFLSEAACMKEFDHPNVMRLIGVCIQ |
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| Kinase | drl.AA | Src | 343-406 | 21 | 0.0011 | 8.34 | In-house | 1-62 (255) | Show / Hide |
Range on Protein: 343-406 Range on HMM: 1-62/255 Sequence Identity: 21% (14 aa) VRLSCLVQEGNFGRIYRGTYNDCQEVLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGI ..| .|.|| . |..|. .| ||| . .... .||| . . .|..... . . IKLCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAV |
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