Gene CG14163 (Fruit Fly)
CG14163
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| CG14163.kin_dom | Protein Kinase Domain | Sugen global kinase HMM prediction | 306 | Kinase domain by global Sugen HMM | Fasta, JSON |
| CG14163.AA | Protein | Various | 693 | None | Fasta, JSON |
Protein domains of CG14163.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | CG14163.AA | SCY1 | 49-352 | 33 | 1.6e-151 | 509.7 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 49-352 Range on HMM: 1-337/337 Sequence Identity: 33% (116 aa) WRIHDAYRKSDNKECSVFIFEKKIAEKLHKPRRKETITELLKSSVKTLERFRHPRILQIYHTVEESADTLAFASEPIFASLSNVLAFHESKTYEATNVAP |.||....|....|||||.|.||..||.||....|.|.|.||...|.|.|.|||.|||..|..||| |....|.|.||..|.|||.....|....|.... WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQ AAGGAAASQAQAAANTLPQRPAHAKEYNFLDMELKYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLAG---------MEYVER-MNENDLNS ..... .||.||||.|.|.... ..|...|..|...|| .||...|..|.|.||.||...|.| ||..| |..| . .|.|. .. DVDFG--------QNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMP SIPCPPW-------------SNRVSKMAQPNLDFMAPETQST-------------SKCSLLSDMFSLGMVICAVFNNGRPLIQAGNS-TSNYAKQMETLD ..||..| .|......|||.|..|||.... .||. |||||||..|..|.|...|.|..... .|.....||... WFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWN DLVHKLMPRLPIALQEA----TSRMASRDATARPTAQLLQLIKYF ...|......| |||. .... ..|.| ||..|......|| AMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF |
|||||||||
| S_TKc | CG14163.AA | S_TKc | 34-352 | 14 | 2.4e-07 | -69.12 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 34-352 Range on HMM: 1-231/231 Sequence Identity: 14% (48 aa) FEIGKPVACAGPELVWRIHDAYRKSDNKECSVFIFEKKIAEKLHKPRRKETITELLKSSVKTLERFRHPRILQIYHTVEESADTLAFASEPIFA---SLS .||.... . |.. .. .. | | | | ... .. |.. .|| | ..| . .. | | . | . .| YEILRKIGKGAFGKVYKCRHKK------------TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLF NVLAFHESKTYEATNVAPAAGGAAASQAQAAANTLPQRPAHAKEYNFLDMELKYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLAGMEYVER .. . .. . . | . .. . |. .||.|.| ..||| . |. ||... |.. . DYIKKRGRHGLR--------------------------------FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQ MNENDLNSSIPCPPWSNRVSKMAQPNLDFMAPETQSTSKCSL-LSDMFSLGMVICAVFNNGRPLIQAGNSTSNYAKQMETLDDLVHKLMPRLPIALQEAT . . ...|||| . . .|. |.| .| . . |.|. . ... . .|.. . . . L-------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG-CILYEMLCGYPPFP-------------QMQMMFKKIG---SPEAKDFI SRMASRDATARPTAQLLQ------LIKYF ... .| . ||||..|| . .| RKCLQKDPEKRPTAEALQDEWDIKCHPWF |
|||||||||
| Kinase | CG14163.AA | Ciliate-E2 | 186-283 | 17 | 2.7e-07 | 21.05 | In-house | 151-286 (365) | Show / Hide |
Range on Protein: 186-283
Range on HMM: 151-286/365
Sequence Identity: 17% (25 aa)
FLQLTE---------------ALAYLHYSGHVIHRNVCPSSILITKRGIWKLAGMEYVERMNENDLNSS-----IPCPPWSNRVSKMAQP----------
. |... || ||| ...|||. |. ||. |.. . . . ... | . .. .|. |..
MKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMF
-----NLDFMAPETQSTSK---------CSLLSDMFSLGMVI
.. .|||| . | . .|..|||...
NTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
|
|||||||||
| Kinase | CG14163.AA | LKB | 186-222 | 35 | 1e-06 | 15.57 | In-house | 110-145 (265) | Show / Hide |
Range on Protein: 186-222 Range on HMM: 110-145/265 Sequence Identity: 35% (13 aa) FLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKL | || ... ||| | .|.|. . |. .|.| .. |. FCQLCDGCEYLH-SQRVVHKDIKPGNLLLTHDNTLKI |
|||||||||
| Kinase | CG14163.AA | NKF4 | 187-215 | 44 | 1e-06 | 16.97 | In-house | 143-170 (336) | Show / Hide |
Range on Protein: 187-215 Range on HMM: 143-170/336 Sequence Identity: 44% (13 aa) LQLTEALAYLHYSGHVIHRNVCPSSILIT .||. |.|.|| . |.||| | .|.|. MQLAQAMAHLH-KNHIIHRDLKPYNIIIV |
|||||||||
| Kinase | CG14163.AA | Ciliate-E2-Unclassified | 177-224 | 28 | 7e-06 | 16.35 | In-house | 135-190 (352) | Show / Hide |
Range on Protein: 177-224 Range on HMM: 135-190/352 Sequence Identity: 28% (16 aa) FLDMELK-----YGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRG---IWKLAG | . . | . | |. ..| |||.....|||. |. ||... | |... FTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIID |
|||||||||
| Kinase | CG14163.AA | ERK7 | 183-223 | 41 | 8e-06 | 15.51 | In-house | 103-142 (292) | Show / Hide |
Range on Protein: 183-223 Range on HMM: 103-142/292 Sequence Identity: 41% (17 aa) KYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLA .| . || |. |.| ||.|||| . || ||. |.. QYIMYQLLRAIKYMH-SGNVIHRDLKPSNILLDSECMVKVC |
|||||||||
| Kinase | CG14163.AA | NEK6 | 183-222 | 47 | 2.2e-05 | 13.43 | In-house | 107-144 (252) | Show / Hide |
Range on Protein: 183-222 Range on HMM: 107-144/252 Sequence Identity: 47% (19 aa) KYGFLQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKL || | ||. ||. .| | |.|| . | . || || || KY-FVQLCSALEHMH-SKRVMHRDIKPANVFITANGIVKL |
|||||||||
| Kinase | CG14163.AA | Dicty3 | 188-222 | 19 | 3.5e-05 | 12.84 | In-house | 119-179 (351) | Show / Hide |
Range on Protein: 188-222 Range on HMM: 119-179/351 Sequence Identity: 19% (12 aa) QLTEALAYLHYSGHVIHRNVCPSSILITKRG--------------------------IWKL .|...|.|.| ..|.|||. . |.. .. .||| DLVKTLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKL |
|||||||||
| Kinase | CG14163.AA | MEK3 | 191-218 | 50 | 4.7e-05 | 13.14 | In-house | 113-140 (264) | Show / Hide |
Range on Protein: 191-218 Range on HMM: 113-140/264 Sequence Identity: 50% (14 aa) EALAYLHYSGHVIHRNVCPSSILITKRG .|| |.| |||| | || .|| . | SALHYMHEQLKVIHRDVKPSNVLINHHG |
|||||||||
| Kinase | CG14163.AA | CDKL | 188-222 | 41 | 0.000103 | 12.04 | In-house | 106-140 (286) | Show / Hide |
Range on Protein: 188-222 Range on HMM: 106-140/286 Sequence Identity: 41% (15 aa) QLTEALAYLHYSGHVIHRNVCPSSILIT-KRGIWKL |. .|....| . .|||.. | |||| | |. || QILKAINFCH-KHNCIHRDIKPENILITPKNGQVKL |
|||||||||
| Kinase | CG14163.AA | TyrKc | 66-352 | 15 | 0.000253 | -152.73 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 66-352
Range on HMM: 1-280/280
Sequence Identity: 15% (52 aa)
FIFEKKIAE------------------KLHKPRRKETITELLKSSVKTLERF--RHPRILQIYHTVEESADTLAF-ASEPIFA--------SLSNVLAFH
..||. | .|.. | . . . . .. .|| |...| . .. | .||.. .| . | |
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKH
ESKTYEATNVAPAAGGAAASQAQAAANTLPQRPAHAKEYNFLDMELKYGF-LQLTEALAYLHYSGHVIHRNVCPSSILITKRGIWKLAGMEYVERMNEND
. | | |. . | .| . .||| | ..||| .|...... | . . |
RPK--------------------------------------LCMKDLLSFCWQIACGMEYLH-SKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDD
LNSSIPCPPWSNRVSKMAQ-PNLDF------MAPETQSTSKCSLLSDMFSLGMVICAVFNNGRPLI-------QAGNSTSNYAKQMETLDDLVHKLMPRL
. | . .... . .. ||||. ..|.. || .| | .. .| .| . .| || . .. . . | .
QQG------ESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-M
-----PIALQEATSRMASRDATARPTAQLLQLIKYF
| .. . .. .|. ||| . . ...|
SFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
|
|||||||||