Gene CG11228 (Fruit Fly)

CG11228

Species: Fruit Fly
Alias: SFO034, CG11228, MST2
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 56E1

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
CG11228.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 252 Kinase domain by global Sugen HMM Fasta, JSON
CG11228.AA Protein Various 596 None Fasta, JSON

Protein domain

Protein domains of CG11228.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG11228.AA MST 42-293 72 3.8e-226 725.95 In-house 1-254 (254) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-254/254
Sequence Identity: 72% (184 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEIIKEISIMQQCDSPYVVRYYGSYF--KQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIA
|||..|||.|||||||||.||....|||||.|||..||.||||||||||||.|.|.|.||||||  |....||.|||||.|||.|||.....||.|..||
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQQIA

TILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEI
.||.|||||| ||| ..||||||||.|||||.||..|||||||.|||||||||||||||||.|||||||.||.|||.||||||||||.|||||.|||..|
CILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPYSDI

HPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
|||||.|||||||||.|..|..||.||.|||.|||.|.|..|.||..||.|.||
HPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase CG11228.AA STE20 42-293 52 3.9e-167 561.56 In-house 1-288 (288) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-288/288
Sequence Identity: 52% (151 aa)

FDIMYKLGEGSYGSVYKAVHKESSSI----VAIKLVPVESD------LHEIIKEISIMQQCDSPYVVRYYGSYFKQ----YDLWICMEYCGAGSVSDIMR
.... |.|.||||.|||| ||..  .    |||| ...|..      ...|.||||||.||..|..|.|||||.|      .|||.|||||.||..|||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---LRKK-----TLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTD----TMA-KRNTVIGTPFWMAPEVIEE----
    ..|     ...|..||.|. ..|||| ||| ...|||||||.||||...| .|||||||..|||.    ||. ||||..|||.|||||||..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-IGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIP--QKPPPSFRE--PDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
  |||. .|||||||||.|||||.||| ..|||||.||||  |.||| ...  |..||.|| |||.|||.|.|..|.||..||.|.||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase CG11228.AA YSK 42-293 52 1.7e-140 425.92 In-house 1-257 (257) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-257/257
Sequence Identity: 52% (136 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEI---IKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRL-RKKTLTEDE
| .  . | ||.| |||.. .    .|||| .  |..  ||    .|| .  ||||||. .||||| |   ||| ||||| ||..| |.      . |  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

IATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEE--IGYDCVADIWSLGITALEMAEGKPP
||.||   |.|| |||  |||||||||||.||. .|  ||.|||||||.|||. |||| .|||.||||||| .   .||  ||||||||||.||| | ||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

YGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
| . ||||. | || ..||.      .|. |..||  ||.|.| .| .| ||| |.||
YCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase CG11228.AA STE 42-293 37 1.8e-139 469.63 In-house 1-359 (359) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-359/359
Sequence Identity: 37% (137 aa)

FDIMYKLGEGSYGSVYKAVHK------ESSSI---------VAIKLVPVESD-------------------LHEIIKEISIMQQCD--SPYVVRYYGSYF
.... |.|.|..|.||||...      ..  .         .||| ...|..                   . .|.|||.||..|.  .|..|.|||.||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KQY-------DLWICMEYCGAGSVSDIMR---LRKKTLT----------EDEIATILSDTLQG-LVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAG
|         .|||||||...||..||..    ..|.|.          |..||.|. ..|.| | |||  ..||||||.|||||     .||.||||.|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLTDTMA----------------KRNTVIGTPFWMAPEVIEE------IGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQK-----------
||||.||                ||||..||| |||||||.        |||. .||||||.|..|||.||||. . |||||.||||..           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPSFRE-----------------PDRWSTEFIDFVSKCLVKEPDDRATATELLE--HEFI
    |||.. .                 |..|| ||.||..|||.|.|..|.||..||.  |.||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CG11228.AA PAKL 42-293 50 8.99999999999e-126 424.14 In-house 1-256 (256) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-256/256
Sequence Identity: 50% (130 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPV-ES-DLHEIIKEISIMQQCDSPYVVRYYGSYFKQ-YDLWICMEYCGAGSVSDIMRLRKKTLTEDEI
| .  |||.|||||||||.||..    |||  .. || .  .| |||.|   | .|..| |.||       .|| |.|| .||. |.| .  |||.| .|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNEKQI

ATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMA-KRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYG
. ||  || ||.||| .  |||||||||||||  .  |.|||||  || |.     |  ||||.|||||.|    |.  .||||||||| |||.| ||  
SVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADGFPPHY

EIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
.. ||||  ||| .||| | .|  || .| ||. .|.|| |  |. . .|| | ||
DMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase CG11228.AA PAKA 42-293 42 7.6e-102 344.66 In-house 1-260 (260) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-260/260
Sequence Identity: 42% (111 aa)

FDIMYKLGEGSYGSVYKAVHKESSSI--VAIKLVPVESDLHE--IIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKK----TL
.. | |.|.|. |.||.|  ..  .   ||||   .. .     || ||..| .|  . .|.|. ||  . .||. ||| ..|.  |.     .    ..
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNYM

TEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGK
.|. || ..  .|||| ..| .  ||||||  ||||...|  |..||| . |||.   ||||. ||| |||||||    ||   ||||||| |.||.|| 
DEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEGE

PPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
||| .  | ||.. | ..  | ...||.|| || ||..||| ...|.||.|.|||.|.|.
PPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase CG11228.AA Ste20-DD1 42-293 45 9.40000000001e-101 341.02 In-house 1-268 (268) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-268/268
Sequence Identity: 45% (122 aa)

FDIMYKLGEGSYGSVYKA-------VHKESSSIVAIKLVPVES----DLHEIIKEISIMQQC-DSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLR
| |.   | ||.| |                 ..|.| | ..     .     ||| |.    | ||.|.| | | |   | | ||||  ||. ||| . 
FQIVEVIGQGSFGVVCTCRWMKKKDRNTNNNRVIACKFVEMNADDVEENSNLKKEIDILKNTMDCPYIVKYHGCYIKENMLMIVMEYCDGGSILDIMQMC

KKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEE----IGYDCVADIWSLGIT
 |.|.|..|| |.    .|||||| .| .|||||| |.|.| || .|||||||   .  .  | ||||| |.||.||.|       |||  |||||||||
SKRLIEEQIAAICYQIVKGLVYLHSNRITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIMPPKGSQGYDQKADIWSLGIT

ALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
| |||| |||  .. | | || || ..||. . |  || || ||.. || ..|| |  | .|| | ||
AIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase CG11228.AA KHS 42-293 46 1.6e-99 335.46 In-house 1-258 (258) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-258/258
Sequence Identity: 46% (121 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVES--DLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIA
.... ..| | || |||| ...|....|.|.. .|   |.  | .|| .|..|  | .| |.|||...  |||||||||.||. || ..  . |.|  ||
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP-LSELQIA

TILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI---EEIGYDCVADIWSLGITALEMAEGKPPY
 .  .||||| ||| . |.||||| |||||. .|  |||||||..|.| |.|||   ||||.||||||     . ||.   |||..||||.|.|| .|| 
YVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQPPM

GEIHPMRAIFMIPQKP--PPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
 ..|||||.|.. .    ||  .. ..||  | .||  .|.|.|  | ||. ||.|.|.
FDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase CG11228.AA S_TKc 42-293 32 9.6e-99 335.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGA--GSVSDIMRLRKK-----TLT
..|. |.|.|..|.|||..||..  ||||| ..       |..||.|... . |..|..|...    .|...||||.   |.. |... |..      ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

EDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGYDC-VADIWSLGITALEMAEGK
| ... ..  ....| |.| .. ||||.| .||||..    |..|||.| ||       .|..|||..|||||.   ||..  .|.||.|..  ||. |.
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

PPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLE-------HEFI
||.     | ..| .              | |..||..|||.|.|..| || |.|.       |...
PPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG11228.AA NinaC 42-293 44 4.9e-94 318.7 In-house 1-267 (267) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-267/267
Sequence Identity: 44% (119 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIK-LVPVESDLHEIIKEISIMQQ-CDSPYVVRYYGSYFKQY-----DLWICMEYCGAGSVSDIMR---LRKK
. |.   | | || |.|.  |.. .|.|.| . ...    ||  |  |... || | |||.|| |.|.       ||. ||||  ||| |. .    . .
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMYYKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCGR

TLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-----EEIGYDCVADIWSLGITA
 . |. || || ... ||  ||  . ||||.|  |||| |||  || ||||  ||. |  .||| .|||.|||||||      .  ||  .|.|||||||
RMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITA

LEMAEGKPPYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
 |.. |.||  ..|||||.| ||  |||  . |. |. || ||.|.|| |.   | . ...||| ||
IELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase CG11228.AA SLK 42-293 42 3.9e-91 307.7 In-house 1-259 (259) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-259/259
Sequence Identity: 42% (110 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVES--DLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIA
..|.  ||.| .| ||||.||| . . | | . ...  .| . . || |. .|. |..|. |..|. . .||. .|.|. | |  ||   ...|||| |.
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQ

TILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI-----EEIGYDCVADIWSLGITALEMAEGKP
 .   ....| .|| .. ||||.|| |||.  .|  .||||||. ... || || | ||||.||||||.      .  ||. ||||||||| .|||.. |
YVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PYGEIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
|. |. ||| .. | .  ||   .| .|| || ||. |||||.|. | |. .|..|...
PHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase CG11228.AA Pkinase 42-293 29 4.6e-87 300.34 Pfam 1-293 (293) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-293/293
Sequence Identity: 29% (88 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEIIK------EISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAG----SVSDIMR-LRK
. |  |.|.||.|.|||..|| .. |||.| ...... ..  .      ||.||. ...|..||.|...    .....||||. |    . .|...  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KTL--TEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYA----KLADFGVAGQL-TDTMAKRNTVIGTPFWMAPEVIE-EIGYDCVADIWSL
...  .|.|.  ..  .|.|| |.| .. ||||.| .|||.. .|.     |..|||.| |. .      .|. |||..||||||    .|.  .|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GITALEMAEGKPPYGEI----HPMRAIFMIPQKPPPSFREPDRWS---------------------TEFIDFVSKCLVKEPDDRATATELLEHEFI
|..  ||. |.||. .     . .. ..|| .. .| ....  |.                      |..||...|| | | .| ||...|.|...
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase CG11228.AA Pkinase_Tyr 42-248 28 8.8e-31 104.87 Pfam 1-228 (270) Show / Hide 
Range on Protein: 42-248
Range on HMM: 1-228/270
Sequence Identity: 28% (65 aa)

FDIMYKLGEGSYGSVYKAVHK----ESSSIVAIKLV--PVESD---LHEIIKEISIMQQC-DSPYVVRYYGSYF-KQYD--LWICMEYCGAGSVSDIMRL
  .. |||||..|.|||.. |    .    ||.| .     ..   . . ..|..|| |  . | .||.||    ..    ..| |||.  |.  |  | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---KKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQL--TDTM-AKRNTVIGTPFWMAPEVIEEIGYDCVADIWSL
.   |. ||  ..  .  .  .|. ||. .. ||||. | |.|.. .. .| .||| |  .  .|.   ||       .|||||.| .  .    |.|| 
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSF

GITALEMAE-GKPP-YGEIHPMRAIFMI
|..  |.   |. | | .. . . . .|
GVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase CG11228.AA TyrKc 42-293 26 3.6e-24 87.53 SMART 1-280 (280) Show / Hide 
Range on Protein: 42-293
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

FDIMYKLGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEIIKEISIMQQC--DSPYVVRYYGSYFKQ-------YDLWICMEYCGAGSVSDIMRLRKKT
     ||||| .| |||.. |     ||.| .  .. . ....|..|| .   . | .|| ||   .|         |.| |||.  |.  |  | ....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDT----MAKRNTVI----GTP-----FWMAPEVIEEIGYDCVADI
|. ..   .  .  .|  ||| .. ||||. | |.|.. .. .| .||| .  ..|      .|   .     |.       |||||.| .  .    |.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSLGITALEMAE-GKPPYGE-----IHPMRAIFMIPQK----PPPS-----FREPDRWSTEFIDFVSKCLVKEPDDRATATELLEHEFI
|| |..  |.   |..|| .     . . ..|  . |     .||.     |    . ..|  .  ..|   .|.|| | .|.  ||..
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Mst1_SARAH CG11228.AA Mst1_SARAH 534-582 57 3.3e-33 109.69 Pfam 1-49 (49) Show / Hide 
Range on Protein: 534-582
Range on HMM: 1-49/49
Sequence Identity: 57% (28 aa)

EFEFLKFLTFDDLNQRLCNIDHEMELEIEQLNKKYNAKRQPIVDAMNAK
.|||||......|.||| ..|..|| |||.|...|.||||||.|||.||
DFEFLKSWSYEELQQRLASLDPMMEQEIEELRQRYQAKRQPILDAMEAK