Gene CG10967 (Fruit Fly)

CG10967

Species: Fruit Fly
Alias: CG10967, UNC 51-like, ATG1, SFO185
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 69E2--4,

Classification

Group: Other
Family: ULK
Subfamily: ULK

Sequence

Name Sequence Type Origin Length Description Download
CG10967.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 266 Kinase domain by global Sugen HMM Fasta, JSON
CG10967.AA Protein Various 835 None Fasta, JSON

Protein domain

Protein domains of CG10967.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CG10967.AA ULK 9-274 34 1.1e-126 427.15 In-house 1-324 (324) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-324/324
Sequence Identity: 34% (112 aa)

YSSKDMLGHGAFA-VVYKGRHRKKH---MPVAIKCITKKGQLKTQN---------LLGKEIKILKELTELHHEN--VVALLDCKESQDC--VSLVMEYCN
|. ...||.|.|. .|||||. |..     ||.|.| ||.. | .|         || .||.|.|.| ||.|.|  .| |.|..|....  . ..|||||
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGDLADYLSVKGTLSEDT----------VRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKT----LPAPSKITLKIADFGFARFLNEGAMAATL
|||| .|.  ...|.| |          .. |. |.. ..|.|. ..|.|||.||||||.... .||    . .| ...|||||||||...... |....
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNNNMEQQM

C----------GSPMYMAPEVIMSL----QYD-SKADLWSLGTIVYQCLTGKAPFYAQTPNELK-------------SYYEQNANLAPKIPS---GVSPD
|          |.|.||||......    .|. .|.|.||||.| |..|.|| ||... .|...              .|..| .. ...|.    .||.
CQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPE

LRDLLLCLLRRNSKDRISYESFFVHRFL
..||. ..| .. ||||| | .| | ..
CKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase CG10967.AA ULK 9-274 34 9.20000000001e-121 407.49 In-house 1-329 (329) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-329/329
Sequence Identity: 34% (114 aa)

YSSKDMLGHGAFAVVYKGRHRKKH----MPVAIKCITKKGQLKTQNL---------LGKEIKILKELTEL-----HHENVVALLDCKESQ--DCVSLVME
|. ...||.|.|..|||||. |..      ||.| | |. . . .|.         | .||||.|.|        ||.|.| |.|..|..  ... ..||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YCNGGDLADYLSVKGTLSEDT----------VRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKT----LPAPSKITLKIADFGFARFLNEG---
||||||| .|.. ...|.|||          .. |. |.. ..|.|. ..|.|||.||||||.. . .||    . .| ...|||||||||......   
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKV-HP-NGVLKIADFGFAKHVDNDNME

---AMAAT----LCGSPMYMAPEVIMSL----QYD-SKADLWSLGTIVYQCLTGKAPFYAQTPNELK-SYYEQNANLAPKIP------------SG----
   .|...    |||.|.||||......    .|. .|.|.||||.| |..|.|| ||||. .|...  ..... |. |..|            .|    
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

VSPDLRDLLLCLLRRNSKDRISYESFFVHRFL
.||...||. ..| .. ||||| | .| | ..
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase CG10967.AA S_TKc 9-274 32 1e-90 308.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-231/231
Sequence Identity: 32% (92 aa)

YSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTELHHENVVALLDCKESQDCVSLVMEYCNG--GDLADYLSVKGT--
|   . .|.|||..|||.||.| .  ||||.|         . . .||.|||.    ||.|.| |.|. .. |.. .|||||.|  ||| ||.  .|.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----LSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFLNEGAMAATLCGSPMYMAPEVIMSLQYDS-KAD
    ..| ..| .. |.. |.. .  .||.||||||.||||..            ..||.|||.||.|       |.||.| ||||||.   .|.  |.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCD

LWSLGTIVYQCLTGKAPFYAQTPNELKSYYEQNANLAPKIPSGVSPDLRDLLLCLLRRNSKDRISYESFFV-------HRFL
 ||.| |.| .|.|. ||.     ...  ...            ||...|..  .|... ..|..    .        | ..
WWSCGCILYEMLCGYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG10967.AA CAMK 14-274 22 2.8e-78 251.69 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-274
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

MLGHGAFAVVYKGRHRKKH------------MPVAIKCITKKGQLK---------------------------TQNLLGKEIKILKELTE----LHHENV
 ||.|.|..|....|..                |||| | ||   .                           ..  . .||.|.| | .    |.|.|.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VALLDCKES-------------------QDCVSLVM---EYCNGG----DLADYLSVK---------------GTLSEDTVRLFLVQLAGAMKALYTKGI
. |..  |.                   .... .||   ||| ||    || ||.  .               | ..|. .| .  |.. |.. .  ..|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHRDLKPQNILLSHNYGKTLPAP--------SKITLKIADFGFARFLNE------------------------GAMAATLCGSPMYMA-PEVIMS-----
||||||| ||||..|.. . | .        .. ..||.|||||.....                        | .  | ||.| ||| |||. .     
VHRDLKPENILLDDNNDDSDP-VEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------LQYDSKADLWSLGTIVYQCLTGKAPFYAQTPN----------ELKSYYEQNANLAPK-IPSG-----------------------VSPDLR
           |. |.| ||.| | | .|.|. |||. . |          ...  .|.  .     .|.                        ||.. .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLLLCLLRRNSKDRISYESFFVHRFL
||. ..|... ..|.. |    | ..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase CG10967.AA Pkinase 9-274 28 3.8e-78 270.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

YSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQN-----LLGKEIKILKELTELHHENVVALLDCKESQDCVSLVMEYCNGG----DLADYL
|  .  .| |.|..|||..|..    ||.|.| |... . ..     |   ||.|.|.|    |.|.| |.|. |. | . .|||||.||    ||.||.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

S--VKGTL--SEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGK-TLPAPSKITLKIADFGFARF--LNEGAMAATLCGSPMYMAPEVIM-S
|   .|..  ||.... .. |.. ... .. .||.||||||.|||...|.   .       ..||.|||.|..  .  .  . |.||.| |||||||. .
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGG

LQYDSKADLWSLGTIVYQCLTGKAPFYAQ----TPNELKSYYEQNANLAPKIPSGVS---------------------PDLRDLLLCLLRRNSKDRISYE
  |..|.| ||.| |.|. |.|. ||. .    . .. .  ....    .. ..  .                     ....|.. ..|... |.|.. |
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

SFFVHRFL
  . | ..
QILQHPWF
Kinase CG10967.AA AGC 9-274 20 6.8e-78 200.14 In-house 1-395 (395) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-395/395
Sequence Identity: 20% (83 aa)

YSSKDMLGHGAFAVVYKGRHRKKH------MPVAIKCITKKG---QLK--TQNLLGKE------------IKILKELTELH-------HENVVA-LLDCK
.  . ..| |.|  ||  |.....         |.|.. ||    ..|  ..     |             .||...   |       | ..|  |  . 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ESQDC--VSLVMEYCN---------GG-DLADYLS---VKGTLSEDTVRLFLVQ-------LAGAMKALYT-KGIVHRD-LKPQNILLSHNYGKTLPAPS
...|   . .||||..         || .|  .|     .|...|...| .. .       .. |.  |   .||.||| ||| |||| ..         
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDED---------

KITLKIADFGFARFLN---------------------------------------------------EGAMAATLCG--SPMYMAPEVIMSLQYDSKADL
   .|..|||..  ..                                                   ..... |.||  .| |||||..    |.  .| 
-GHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDW

WS--LGTIVYQCLTGKAPFYAQTPN-------ELKSYYEQNA------NLAPKIP----------SGVSPDLRDLLLCLLRRNSKDRIS----------Y
||  || . |. |||. |||...|.         .  ...        |  .|.|          . .||...||.  || .. ..|.           .
WSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGA

ESFFVHRFL
|    | . 
EEIKNHPWF
Kinase CG10967.AA CAMKL 9-274 30 2.9e-72 229.89 In-house 1-297 (297) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-297/297
Sequence Identity: 30% (95 aa)

YSSKDMLGHGAFAVVYKGRHRKK-HMPVAIKCITKKGQLKTQNLLGK--------------EIKILKELTELH-HENVVALLDCKESQDC------VSLV
|   . ||.|.|..|  ..|..     |||| | ||.  . .. . .              ||.|.| |     |.|.. |... | ...      . ||
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLN-IGKHPNIIKLYEVIETPEHDIETKKIYLV

MEYCNGGD--LADYLSVK----GTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFLNE-----GAMAA
|||| ||.  | ||.  .    | ..|.  | .  |.  |.. .  .||||||.|| ||||..|           ..||.||||. .  .     | .  
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN--------NIKIIDFGFSNMYRPCIFGPGQKLK

TLCGSPMYMAPEVIMS--LQYD-SKADLWSLGTIVYQCLTGKAPFYAQTPN-----ELKSYYEQNANLAPKIP--SGVSPDLRDLLLCLLRRNSKDRISY
| |||| |||||.. .   .||  |.| ||.| | |  ..|. || ..| |         .|...  .  ..|  . || |.|||.  .| .| ..|.. 
TFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI

ESFFVHRFL
.    |...
HQIMNHPWM
Kinase CG10967.AA Ciliate-E2 9-274 21 2.4e-69 236.72 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-365/365
Sequence Identity: 21% (85 aa)

YSSKDMLGHGAFAVVYKGRH-RKKHMP-----------------VAIKCITKKGQLKTQ-NLLGKEIKILKELT-------------ELHHENVVALLDC
|    ..| |.|..|||... .....                  |.|| . .| . | | . . .||.|..|.              .| | |.. . .|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

KE--SQDCVSLVMEYCNGGDLADYLSVKGTLS-----------EDTVRLFLVQLAG---------------AMKALYTKG-IVHRDLKPQNILLSHNYGK
 .  ..... ||||||.|||| ||.  . . .           |  .. .  |..                |.. |  |. |.|||.||.|||.      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

TLPAPSKITLKIADFGFARFLNEG--------------------------------AMAATLCGSPMYMAPEVIMSLQ---------YDSKADLWSLGTI
         .||.|||.......                                  |. |.||.|.|||||.... .         || |.|.|||| |
---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

VYQCLTGKAPFYAQTPNELKSYYEQNANLAPK--------------IPSGVSPDLRDLLLC----LLRRNSKDRIS-YESFFVHRFL
 |..|.|| ||       ..   ... .. ..              ..  .|..  ||.      .| .. . ||. .|  . | ..
LYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase CG10967.AA CAMK1 9-225 35 2.6e-65 188.78 In-house 1-225 (276) Show / Hide 
Range on Protein: 9-225
Range on HMM: 1-225/276
Sequence Identity: 35% (83 aa)

YSSKDMLGHGAFAVVYKGRHRKK---HMPVAIKCITKKGQLKT-----QNLLGKEIKILKELTELHHENVVALLDCKESQDCVSLVMEYCNGGDLADYLS
|  ....| |||..||.. |...     ..||||| || ..|.     |..| .|| |.| . ...|.|.... .  || . . ||||...||.| |   
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV

VKGTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLK--IADFGFARFLNEGA-MAATLCGSPMYMAPEVIMS---LQY
 ||  .|.  |.   |...| . .  ||||||||||.|.|.. ..          ..|  ||||| .......  .  | ||.| |.||||.       |
EKGNYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLLYYDKDEDS-------KIKRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPY

DSKADLWSLGTIVYQCLTGKAPFYAQT-PNEL
| . |.|| | | |  |.|  |||. .  |||
DKACDMWSIGVITYILLCGYPPFYDENVDNEL
Kinase CG10967.AA Ciliate-E2-Unclassified 9-274 24 3.1e-63 216.41 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-352/352
Sequence Identity: 24% (87 aa)

YSSKDMLGHGAFAVVYKGRHRKKHMPV-----AIKCITKKGQLKTQN----LLGKEIKILK-------------ELTELHHENVVALLDCKESQDCVSLV
|     .|.|.|..||| .|.|.   .     ..| . .| ... ..    .  ||....|             .|  . |...| ...|....... .|
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEYCNGGDLADYLSVKGT-----------------LSEDTVR-----LFLVQLAGAMKALYTKG-IVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFG
||||.|||| .|.. ...                 ..|  ..      .. |.  . . |  |. |.|||.||.|||.. | .       .  .||.|||
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-------NYYIKIIDFG

FARFLNEG----------------AMAATLCGSPMYM----APEVIMSLQYD----SKADLWSLGTIVYQCLTGKAPFYAQTPNE-------------LK
.......                  |. | ||.|.||    ||||... .||     |.| |||| | |..|.|. |||... ..              |
ISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRK

SYYEQNANL------APK--IPSGVSPDLRDLLL----CLLRRNSKDRISYESFFVHRFL
 .|..  .       .|.  || ..||   |..     ..|  | . ||..|  . | ..
QLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase CG10967.AA STE 9-274 21 3.2e-61 209.69 In-house 1-359 (359) Show / Hide 
Range on Protein: 9-274
Range on HMM: 1-359/359
Sequence Identity: 21% (81 aa)

YSSKDMLGHGAFAVVYKGRHRK---------------KHMPVAIKCITKKGQL----------------KTQNLLGKEIKILKELTELHHENVVALLDCK
.   ...|.||| .|||....|               ..  .||| . .. .                 . .. . |||||.|..    |.|.|  ..| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

ESQ-------DCVSLVMEYCNGGDLADYLS-VKGTLS-------------EDTVRLFLVQLAGA-MKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKI
.         | . ..|||..|| | | .  ..|..              |. .. ...|.  . .. |  ..|.|||.||.||||              
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------------

TLKIADFGFARFLNE-GA----------------MAATLCGSPMYMAPEVIMS------LQYDSKADLWSLGTIVYQCLTGKAPFYAQTPNELKSYYEQN
  |..|||..  |.. .|                .  |..|.| .||||||.        .|| |.| ||||  .   .||| |.   .| .   .  .|
-VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFN

A-------------NLAPKIPS-------------------GVSPDLRDLLLCLLRRNSKDRISYESFFV--HRFL
              .  |..|.                    .||...| .   |... ..| ...      | |.
YHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase CG10967.AA RAD53 9-217 32 3.8e-61 180.66 In-house 1-241 (305) Show / Hide 
Range on Protein: 9-217
Range on HMM: 1-241/305
Sequence Identity: 32% (80 aa)

YSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITK-------KGQLKTQNLLGKEIKILKELTELHHENVVALLDCKES-QDCVSLVMEYCNGGDLADYL-
|.   .|| |.|..|...  .|    |||| | |         . |.   . .|..|||    |.|.......|. .. |. ...|.|. .||.| . . 
YYMSKELGSGNFGTVKLAYEKKTCQKVAIKIIDKKKFFIRCMHTIKKMDQVMNEVEILK---KLNHPCIIRIYDIFDTPQKYYYMVLELMTGGELFNKIV

SVKGT---LSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKT--------LPAPSKITLKIADFGFARFLNEGAMAATLCGSPMYMAPEV
| |.    ..||| .... |.  | | |  .||.|||||| |||..|.   .              . .||.||| ..|. || .. |.||.| | ||||
SNKRCQMGFDEDTCKYYFYQMCDAVKYLHDNGICHRDLKPENILCNHQDEECPQVQLGPWDEDEISFLIKITDFGLSKFVGEGSFMKTMCGTPQYVAPEV

IMSL---------------QYDSKADLWSLGTIVYQCLTGKAPF
| |                 | .| |.||.| |.| ||.|  ||
ITSKGHNCYHENEERQVQVGYTKKVDCWSMGCILYICLCGYPPF
Kinase CG10967.AA Pkinase_Tyr 9-204 30 7.4e-28 94.96 Pfam 1-201 (270) Show / Hide 
Range on Protein: 9-204
Range on HMM: 1-201/270
Sequence Identity: 30% (65 aa)

YSSKDMLGHGAFAVVYKGRHR----KKHMPVAIKCITKKGQLK---TQNLLGKEIKILKELTEL-HHENVVALLDCKE-SQDC--VSLVMEYCNGGDLAD
 .   .||.||| .||||. .    ....|||.|..  .   .    . ..  |.||.|   .| ||.|.| |. .    ..   . .||||. .||| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMK---QLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YLSV----KGTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFL-NEGAM--AATLCGSPM-YMAPEVI
||      |. |.  .   . .| | .|  |  |...||||   |.|...          . . ||.||| || . |..    ... .  |   ||||.|
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----------NNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECI

MSLQYDSKADLWSLG
.   . .| | || |
NYGKFTTKSDVWSFG
Kinase CG10967.AA TyrKc 9-273 23 2.7e-21 77.97 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-273
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

YSSKDMLGHGAFAVVYKGRHRKKHMPVAIKCITKKGQLKTQNLLGKEIKILKELTEL--HHENVVALLDCKESQ-------DCVSLVMEYCNGGDLADYL
 . ...||.||| .||||. .   ..||.|.. .      .  . .|..|..   .|  ||.|.|.|. .  .|       . . .||||. .||| |||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMC---KLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

-SVKGTLSEDTVRLFLVQLAGAMKALYTKGIVHRDLKPQNILLSHNYGKTLPAPSKITLKIADFGFARFLNEG--------AMAATLCGSPM------YM
 . ...|. ..   | .| |  |  |  |...||||   |.|...|.          | ||.||| .|.. ..           ..  ..         |
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APEVIMSLQYDSKADLWSLGTIVYQCLTGKAPFYAQ-----TPNELKSYYEQNANLAPKIPSG-------VSPDLRDLLLCLLRRNSKDRISYESFFVHR
|||.|.   . .| | || |   .  .|  .. |        .|.    | .. .  |. |..        .... .. ..  ... .|| . .   ...
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HEC

F
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F
Kinase CG10967.AA CAMK1 249-274 23 0.00837 3.91 In-house 251-276 (276) Show / Hide 
Range on Protein: 249-274
Range on HMM: 251-276/276
Sequence Identity: 23% (6 aa)

DLLLCLLRRNSKDRISYESFFVHRFL
|.. ..|  . | |...| .  |...
DFIKHMLEVDPKKRYTCEQCLNHPWI
DUF3543 CG10967.AA DUF3543 614-827 22 2.1e-82 284.87 Pfam 1-275 (275) Show / Hide 
Range on Protein: 614-827
Range on HMM: 1-275/275
Sequence Identity: 22% (63 aa)

ETLMDREHNETLSKLNFVLALTDCIQEVADSRCAPLSTFM--VAGSQSAAQAA------SADAQQIPPHAPEHCKRAERLVLLVRGLQLLSSGMNLASQQ
.|.||.||..|..||.......||. ..|......|.  |  | .........      ... ....|.|....|..|.||| |. |.||...|..||..
QTSMDDEHTRTVQKLEECATRSDCVYGFAEVKYKQLIPLMPSVSTYGLGDANVQGRDDSMHQDDGLTPDAIVTWKSEEALVLYVKALSLLAKSMDIASAW

LSN--------------GQLKP-SSNVKNALLTMNAKYRSMLFESKRLNGSG-----LLQKAN----------------------AFNITADKILYDYAL
 ..              .||.| |. ..... ........ | ... ..  .     .|....                      . ..||.|..|| ||
WYRKNRGEDFNMTRDSSNQLCPTSNRINQVVQWIRERFNECLEKCEFVRLKLQEAQKRLPEDHPSHPKNHSNESSSSGSSNDVVVSSGVTAEKLMYDRAL

DMCQAAALDELLK-NTKNCFERYNTAHILLHSLVQKC----------NHPQDKMMLNKYRDAVEKRLSILQQHGY
.|...||..|| . ....|. .| ||...|..| ...          ....||.|..|| ....||||.|....|
EMSRTAAINELFGEDLPGCEIAYHTAIWMLEALLENDEDEDKDENDGLDDEDKQMVEKYIVSIRKRLSVLRKKMY